When consuming food, the blood sugar levels rise, the pancreas responds by releasing insulin to reduce blood sugar to normal levels, however when diets are high in carbs, the pancreas becomes less sensitive to blood sugar fluctuations, in other words it becomes resistant to sugar spikes in the blood, leading to sustained high blood sugar levels which because of this leads to insulin resistance. Fructose itself has added significance because of its role in the brain that evolved to facilitate survival over millenia. Back then fructose was scarce, today it is in abundance.
@@happyhabitpodcast It´s just a weird thing to state, given that frustose is way less interacting with insulin than every other carb. High fructose consumption might be a high risc factor in getting a fatty liver but there´s a reason why its used as a saccharose substitute for diabetes patients: very low interaction with insulin.
Fructose stimulates insulin secretion less than does glucose and glucose-containing carbohydrates , there's no argument there, but fructose will still have an impact on insulin secretion especially if you're consuming a modern western diet. Remember the key point made in the video is fructose triggers a foraging response, this is an ancient survival mechanism that has been exploited by modern makers of processed foods.
There are 2 pathways: 1st fructose (like alcohol) is just metabolized in the liver and not in any other organ of the body unlike fats and glucose. So it particularly affects the liver, leading to fatty liver disease and fatty liver has serious consequences in the rest of the body including insulin resistance. Fructose also affects ATP production in mitochondria, making the brain think that the body is depleted of energy, making the brain turn on hunger signals. Experiments in which obese children just had a diet in which fructose was substituted by glucose, resulted in improved metabolic markers. But Dr Johnson warns us not to eat highly processed starchy food, because it is digested quickly and activates the polyol pathway in which glucose is converted to fructose
Why does fructose cause insulin resistance? Fructose does not use insulin.
When consuming food, the blood sugar levels rise, the pancreas responds by releasing insulin to reduce blood sugar to normal levels, however when diets are high in carbs, the pancreas becomes less sensitive to blood sugar fluctuations, in other words it becomes resistant to sugar spikes in the blood, leading to sustained high blood sugar levels which because of this leads to insulin resistance. Fructose itself has added significance because of its role in the brain that evolved to facilitate survival over millenia. Back then fructose was scarce, today it is in abundance.
@@happyhabitpodcast It´s just a weird thing to state, given that frustose is way less interacting with insulin than every other carb. High fructose consumption might be a high risc factor in getting a fatty liver but there´s a reason why its used as a saccharose substitute for diabetes patients: very low interaction with insulin.
Fructose stimulates insulin secretion less than does glucose and glucose-containing carbohydrates , there's no argument there, but fructose will still have an impact on insulin secretion especially if you're consuming a modern western diet. Remember the key point made in the video is fructose triggers a foraging response, this is an ancient survival mechanism that has been exploited by modern makers of processed foods.
There are 2 pathways: 1st fructose (like alcohol) is just metabolized in the liver and not in any other organ of the body unlike fats and glucose. So it particularly affects the liver, leading to fatty liver disease and fatty liver has serious consequences in the rest of the body including insulin resistance. Fructose also affects ATP production in mitochondria, making the brain think that the body is depleted of energy, making the brain turn on hunger signals. Experiments in which obese children just had a diet in which fructose was substituted by glucose, resulted in improved metabolic markers. But Dr Johnson warns us not to eat highly processed starchy food, because it is digested quickly and activates the polyol pathway in which glucose is converted to fructose
@@nataliajimenez1870 you know science, thanks for watching
Why all the keto/fasting guys are so old? Is it because they no longer need high energy and high libido which require sugar?