Clonal selection | Immune system physiology | NCLEX-RN | Khan Academy

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  • เผยแพร่เมื่อ 20 ม.ค. 2025

ความคิดเห็น • 87

  • @EhabAhmed-to1ol
    @EhabAhmed-to1ol 8 ปีที่แล้ว +195

    Both t and b cells are formed in bone marrow but t cells are matured in thymus

    • @paulhetherington3854
      @paulhetherington3854 4 ปีที่แล้ว

      Funny chest, is so wide-- and guts area-- T U B-- influence of bones-- positions. You know nothin-- about infusion-- osmosis. Head-- flows blood down-- first. Ancient Alpha Beta-- First 2-- which means-- grids.

    • @birajbanker
      @birajbanker 3 ปีที่แล้ว +2

      Tyvm for the additional info bro

    • @arshiatalebi3217
      @arshiatalebi3217 3 ปีที่แล้ว

      Dont lie u learned that from the previous video XD

  • @NLaw-uo5uk
    @NLaw-uo5uk 9 ปีที่แล้ว +59

    I love Khan Academy Videos...You guys are the best at explaining things I need to know in a refreshing and comprehensive manner; without all the extra music, mumbling and distracting qualities that can be in other videos...Can't say enough how much you guys help me. THANK YOU :)

    • @nilupadushanthi
      @nilupadushanthi 4 ปีที่แล้ว +1

      I learned statistics from Khan academy videos more than I learned from my uni lecturers! Thank you so much.💐

  • @jared394
    @jared394 10 ปีที่แล้ว +53

    T cells mature in the Thymus and originate from the bone marrow, according to my test. This is probably not too important though, thank you for the review.

  • @AriesHolmes
    @AriesHolmes 7 ปีที่แล้ว +7

    This explanation helped me so much. Its clear, step by step and emphasizes the areas where people might get confused. I used to mix up the replication wherein they will get different receptors (for diversity) with the replication wherein they will have the same receptor (for actually responding to the infection) all cleared up now. thanks

  • @poova06
    @poova06 3 ปีที่แล้ว

    wow i literally did not understood what my lecturer said, but this changed all. thank you for this video, life saver!

  • @bengavagan
    @bengavagan 6 ปีที่แล้ว +3

    You are literally a life saver, missed a bit of class and this has brought me right up to date!

  • @lilymoore3955
    @lilymoore3955 9 ปีที่แล้ว +9

    perfectly explained. thank you!

  • @lissyyy6865
    @lissyyy6865 3 ปีที่แล้ว

    I just want to thank you for using easy english in the explanation haha. I’m german but somehow there is no video in german that explains this topic as good as you guys. I’m so thankful that i could understand anything you said cuz you didn’t use many complicated expressions

  • @AuggieX1
    @AuggieX1 6 ปีที่แล้ว +2

    Thank you… Very simple way of explaining a complex concepts.

  • @dudedude9528
    @dudedude9528 3 ปีที่แล้ว

    Thanks so much I was feeling very depressed because I was not understanding my textbook but now there’s hope

  • @Johndoe3786.
    @Johndoe3786. 5 ปีที่แล้ว +1

    These videos are really helping me through my degree, thank you Khan Academy 👍🏻👍🏻

  • @NikkiPea12
    @NikkiPea12 9 ปีที่แล้ว +3

    Wonderfully done! I finally understand this a lot better now as it put all the little pieces together! =D Thanks.

  • @ilimselyardm9698
    @ilimselyardm9698 3 ปีที่แล้ว

    SubhanAllah , thank you sir may Allah bless you :)

  • @lauranewman1091
    @lauranewman1091 4 ปีที่แล้ว

    best video, been trying to learn this for weeks

  • @ordinarymind1804
    @ordinarymind1804 10 ปีที่แล้ว +3

    Thanks for making this video. It's awesome!

  • @rockmamabaker8370
    @rockmamabaker8370 4 ปีที่แล้ว

    Amazing video! Made everything clear for me! Thank you!!! 😀👍

  • @crystallane4671
    @crystallane4671 3 ปีที่แล้ว

    This helped me tremendously!! Thank you!

  • @nicorogervonlohengramm
    @nicorogervonlohengramm 2 ปีที่แล้ว

    Wow, thank you so much, Mr.

  • @emmawright663
    @emmawright663 ปีที่แล้ว

    wow this is the best video ever

  • @SaraSiraj
    @SaraSiraj 7 ปีที่แล้ว +1

    Best explanation ever !

  • @sejalsiddha1879
    @sejalsiddha1879 4 ปีที่แล้ว

    I needed this so much... really nice video 👍👍

  • @JustPiichi
    @JustPiichi 10 ปีที่แล้ว +3

    Thanks, I really needed this.

  • @Samira-khudiya
    @Samira-khudiya 8 ปีที่แล้ว +1

    I found it useful and easy..thanks

  • @sciencenerd7639
    @sciencenerd7639 2 ปีที่แล้ว

    Wow, thanks, this is very well explained!

  • @blossomenoragbon6642
    @blossomenoragbon6642 ปีที่แล้ว

    Thanks!!! This was so helpful

  • @zainabsuleyman621
    @zainabsuleyman621 2 ปีที่แล้ว

    Even after 8 years...thank you

  • @simrankashyap5299
    @simrankashyap5299 5 ปีที่แล้ว +1

    Thanks sir 😊

  • @Jessedaps
    @Jessedaps 9 ปีที่แล้ว +7

    perfect explanation

  • @goddesswithinme9
    @goddesswithinme9 3 ปีที่แล้ว

    Awesome😊😊👏👏👏👏

  • @backstreetfan2887
    @backstreetfan2887 4 ปีที่แล้ว

    thank you khan academy

  • @MasterDisaster95
    @MasterDisaster95 9 ปีที่แล้ว +5

    Thanx for making my life easier LOL

  • @soumyanr2442
    @soumyanr2442 2 ปีที่แล้ว

    And they starting replicating like crazy😄

  • @Ray-jg1bw
    @Ray-jg1bw 7 ปีที่แล้ว +1

    Wow that cleared things up. Thank you! :)

  • @srirambhardwaj2343
    @srirambhardwaj2343 5 ปีที่แล้ว +1

    Thank.you.very.much.sir .

  • @zainabbatool1832
    @zainabbatool1832 7 หลายเดือนก่อน

    very informative

  • @hamadalayyaf5361
    @hamadalayyaf5361 7 ปีที่แล้ว +2

    very clear.. Thanks ♡

  • @VasupradhaS.H
    @VasupradhaS.H 11 หลายเดือนก่อน

    best explanation

  • @unknown-fz7nn
    @unknown-fz7nn 7 หลายเดือนก่อน

    thank you thank you thank you

  • @saraanicole9
    @saraanicole9 8 ปีที่แล้ว +1

    You didn't talk about the co-stimulatory stimulus needed for T cell activation

  • @forzamilan1924
    @forzamilan1924 8 ปีที่แล้ว

    an excellent video to resum Immunology .

  • @bismanaeem6684
    @bismanaeem6684 9 หลายเดือนก่อน

    Havent seen anything better yet simpler than this ❤

  • @khaledfrihat1496
    @khaledfrihat1496 5 ปีที่แล้ว

    such a great job,thank you

  • @ashleyhuber1610
    @ashleyhuber1610 9 ปีที่แล้ว +3

    Hi there. My understanding is that with B-cells (and thus, humoral immunity), APC's do not play a role. Yet in your presentation, you reference APC's presenting bacteria to B-cells. Could you clarify?

    • @shehreeze1022
      @shehreeze1022 5 ปีที่แล้ว

      No, in this video, his drawing shows that APC's are presenting the antigen to the T-cells. Also, this is probably way overdue, but B-cells can be APC's themselves.

  • @yazhiniram5443
    @yazhiniram5443 4 ปีที่แล้ว

    This is amazing

  • @lydiamwasu7646
    @lydiamwasu7646 7 ปีที่แล้ว

    Thanks alot,the info is really helpful

  • @notsilentobserver5064
    @notsilentobserver5064 4 ปีที่แล้ว

    Is it possible that we don't have a receptor for a particular pathogen?

  • @ss-nu8xx
    @ss-nu8xx ปีที่แล้ว

    You are great

  • @sarahward5974
    @sarahward5974 4 ปีที่แล้ว

    Really great, thank you :)

  • @Silverxlife
    @Silverxlife 6 ปีที่แล้ว

    Amazing !!

  • @genesisperalta5963
    @genesisperalta5963 10 ปีที่แล้ว

    Amazing! Thanks a lot!

  • @farbodniazi6504
    @farbodniazi6504 6 ปีที่แล้ว

    You didn't actually talk about the clonal selection theory which talks about the diversity of antibodies and how their constant portion is made from a different gene than the variable segment.

  • @mohammadalzoabi3888
    @mohammadalzoabi3888 7 ปีที่แล้ว

    thank you very much

  • @nahmlj3540
    @nahmlj3540 4 ปีที่แล้ว

    thank u

  • @PistonsFanFourEver
    @PistonsFanFourEver 9 ปีที่แล้ว

    Thank You!

  • @mawabomawabo5507
    @mawabomawabo5507 9 ปีที่แล้ว

    thank you

  • @arlsffa
    @arlsffa 6 ปีที่แล้ว

    perfect...

  • @CrazycruxGaming
    @CrazycruxGaming 7 ปีที่แล้ว +1

    You forgot T-dependent B-cells and T independent. T independent B cells are the only ones that can bind to the antigens on the bacterium's surface (epitopes like LPS and proteins. Other B-cells have to have the T-helper cells that differentiated out present antigens and stimulate them. Other than that, great video! You guys seriously help so many people!

  • @helhkr
    @helhkr 10 ปีที่แล้ว +1

    thank you very much for all this valuable material. In this video you explain clonal selection and clonal expansion, right?

  • @anteater2536
    @anteater2536 6 ปีที่แล้ว

    thanks

  • @faridsaid9180
    @faridsaid9180 3 ปีที่แล้ว

    How about NK-CELLS?

  • @medicalstudy2931
    @medicalstudy2931 5 ปีที่แล้ว

    Hey you first tell that the dendritic cells present the bacterial pieces to B and T cells and later you tell that the B cells don't actually need the antigen presenting cells they are able to react to the bacteria directly. Is there any mistake in the first statement? BTW the video is really nice.

    • @shehreeze1022
      @shehreeze1022 5 ปีที่แล้ว

      same confusion here

    • @nicodasm
      @nicodasm 5 ปีที่แล้ว

      Dendritics do present to Bcs, but Bcs don`t really need that. However, it helps!

  • @sabirsheikh7426
    @sabirsheikh7426 7 ปีที่แล้ว

    When army of same B cells or T cells are produced....then as they are same bcz they r produced by colonial section......but the antibodies produced by them or the activated T cells produced by them same?????.....and if they are same it means they require only one type of antigen so one gene codes for them???????.....r they produce different kind of antibodies????I am getting confuse about this point....plzzz tell me??????

  • @phutijulia1067
    @phutijulia1067 2 ปีที่แล้ว

    What happens after a B-cell kills an antigen?

  • @yourfriends
    @yourfriends 3 ปีที่แล้ว

    Clonal expansion & selection are two separate processes!

  • @hermanfourie66
    @hermanfourie66 4 ปีที่แล้ว +1

    If i understand the video correctly, you are saying that antibody production is just a matter of luck? And if you were not lucky enough to have a B-cell that has the correct antibody for a specific antigen, then you just die? Would you please explain this? I am super confused because this video ( th-cam.com/video/Bl6vWLqL2D0/w-d-xo.html ) kind of suggests that antibody production is not a matter of luck, but rather a matter of the body creating a specific antibody for a specific antigen, rather than having an antigen just fitting an antibody by a chance of luck.

  • @femi9000
    @femi9000 4 ปีที่แล้ว

    6:33

  • @alessiamartina
    @alessiamartina 5 ปีที่แล้ว

    why is that clonal selection, I'd rather call that selective cloning... Btw thank you Patrick!! I love Khan academy

  • @Friendy54792
    @Friendy54792 5 ปีที่แล้ว

    Thought 7:28 and after was so funny lol esp at 2x speed

  • @melissas4079
    @melissas4079 ปีที่แล้ว

    the way he is drawinggg

  • @tiktokhub4298
    @tiktokhub4298 2 ปีที่แล้ว

    yo the thymus is found around the neck not the sternum

  • @aprilrussano3433
    @aprilrussano3433 5 ปีที่แล้ว

    Don’t B cells get activated by T cells (cd4)

  • @marcthongvilu1676
    @marcthongvilu1676 4 ปีที่แล้ว

    I guess T-helper cells don’t exist anymore

  • @paulhetherington3854
    @paulhetherington3854 4 ปีที่แล้ว

    Im-- gay, or of with! Kaldean and Koine Egyptian languages. No BDZKL-- this is, two celled! DNA-- > DZNA-- This is, not internal medicine! You should learn, language, before speak? MEDZ TDZKL-- This is,
    me, and my-- chest cells or, T-cells. Shoulders are, attached as the, T- branches of, arms -- lungs.

  • @LetsGettosubscribersWithOnlyVi
    @LetsGettosubscribersWithOnlyVi 6 ปีที่แล้ว

    You are a life saver check out mmbone.com

  • @erikarvidsson1360
    @erikarvidsson1360 5 ปีที่แล้ว

    I am quite offended, was this all that the author had to know in his med school? If this video is intended for schoolkids, please dont pretend it is medicine. You simplified it so much that many things are just wrong, you also forgot to mention almost everything. Its like putting the entire bible in a sticky note: Some dude died for other peoples sins and got resurrected by his father who lives in fluffy clouds and murders the whole world from time to time.
    I think Christians would not like my short version of the bible, and that is how I feel about this video.

  • @poojakashyap6713
    @poojakashyap6713 2 ปีที่แล้ว

    Thankyou so much 🙏

  • @abdal-rahmansalous6032
    @abdal-rahmansalous6032 2 ปีที่แล้ว

    thanks

  • @rheageorge2902
    @rheageorge2902 3 ปีที่แล้ว

    Thankyou so much

  • @sunnyoh3927
    @sunnyoh3927 2 ปีที่แล้ว

    thanks a lot