Virology Lectures 2024 #4: Structure of viruses

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  • เผยแพร่เมื่อ 29 ม.ค. 2024
  • Viral particles must not only protect the genome in its journey among hosts, but also come apart under the right conditions to release the genome into cells, a property called metastability. In this lecture we describe the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss how to make small and large viruses, the triangulation number, quasiequivalence, and other components of virus particles such as spike glycoproteins and a lipid membrane.
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ความคิดเห็น • 9

  • @zhansayabauyrzhanova2492
    @zhansayabauyrzhanova2492 วันที่ผ่านมา

    i did nt get this part: how pentamers in 60 subunit proteins made of only 5 subunits. pentamer 5x VP1, while T=3, 180 subunits 5x 3 = 15 subunits (VP1x5, VP2x5, VP3x5), right? if hexamer then, 18 subunits, right? can u elaborate on this, please?

  • @zhansayabauyrzhanova2492
    @zhansayabauyrzhanova2492 วันที่ผ่านมา

    51:00

  • @climjames1677
    @climjames1677 4 หลายเดือนก่อน +1

    20:00 the freezing method, I'm thinking they very slowly froze the virus and photographed the physical changes as it froze and from those snap shots they built a possible image. Am I close or far away? (Not a med student just interested.)

    • @zhansayabauyrzhanova2492
      @zhansayabauyrzhanova2492 วันที่ผ่านมา

      i did nt get this part: how pentamers in 60 subunit proteins made of only 5 subunits. pentamer 5x VP1, while T=3, 180 subunits 5x 3 = 15 subunits (VP1x5, VP2x5, VP3x5), right? if hexamer then, 18 subunits, right? can u elaborate on this, please?

  • @WillNewcomb
    @WillNewcomb 4 หลายเดือนก่อน +1

    Mmm? Not sure if I'll listen. #2 & #3 were way beyond me! But I don't want to miss out on some gems!

    • @climjames1677
      @climjames1677 4 หลายเดือนก่อน +4

      never let your lack of current understanding keep you from dipping in, lest ye never learn.

    • @WillNewcomb
      @WillNewcomb 4 หลายเดือนก่อน +3

      @@climjames1677 Perhaps I'll listen tonight! Thanks!

    • @WillNewcomb
      @WillNewcomb 4 หลายเดือนก่อน +2

      Pretty pictures! That about sums up my comprehension of this lecture haha!!!

    • @zhansayabauyrzhanova2492
      @zhansayabauyrzhanova2492 วันที่ผ่านมา

      i did nt get this part: how pentamers in 60 subunit proteins made of only 5 subunits. pentamer 5x VP1, while T=8, 180 subunits 5x 3 = 15 subunits (VP1x5, VP2x5, VP3x5), right? if hexamer then, 18 subunits, right? can u elaborate on this, please?