Are you Feeling Lucky? Fructose vs Glucose & Sucrose
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- เผยแพร่เมื่อ 20 ก.ย. 2024
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ABOUT THIS VIDEO:
Does fructose really have a significant metabolic impact compared to glucose and sucrose? This article compared immediate impact of 50g Fructose to 50g of Glucose and 50g of sucrose. The immediate results were very different and very interesting.
www.ncbi.nlm.n...
Fructose didn't raise blood glucose, insulin or triglyceride level.Glucose and Sucrose did. On the other hand, Fructose caused an immediate rise in CV inflammation as measure by C Reactive Protein. Fructose also caused immediate rises in cholesterol values.
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Dr. Brewer started as an Emergency Doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, he went on the run the post-graduate training program (residency) in Preventive Medicine. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, and stroke prevention clinic.
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Another video that demonstrates that we should not listen to anyone. :-) Excellent balanced video.
Thanks
Lustig said that the reason fructose doesn't spike blood glucose is because it must first be processed in the liver. The reason that it's so bad, and acts like alcohol - is because it's hard on the liver. That would explain the spike in CRP, too.
Thanks.
Yes I was also thinking same thing..any thing our body can't process after absorbing puts a load on our liver and after that on our kidney
all i wanted to know in watching this video is whether or not i could eat an apple, banana and oranges for dessert without harming my arteries, not when fructose is added to a drink.
"Feeling lucky"? Great title. My life is significantly better because of your efforts that inform us properly of what the literature is finding in all of the salient studies concerning aging. I can't thank you enough. God Bless you and your family.
Isn't this gratifying when someone says that some of the videos help them. I am a great fan of Dr. B.
Thank you very much!!
Enjoyed this man's presentation. Provided information, gave an opinion but did not seem to have preconcieved paradigm to shill for.
Thankyou!!
Thanks.
Thank you for your presentation. I just had a small sweet potato (I could wrap my hand around it) with almond butter (plain, organic with salt) and a pat of Kerry Gold. Now I gotta use my search engine to see what kind of sugar it is that I ate before I take my afternoon walk. I'll be back to the low carbohydrate high fat for the next week or so. Still learning about this and intermittent fasting. I've been doing my version of High Intensity Intervale Training since I saw your recommendation. It takes me around an hour to get 2 miles. There are 6 park benches where I stop and do pushups on the seat. So I will do between 125 and 150 pushups and 75 to 125 pull-ups on the chest high parallel bar. Actually, they are half pull-ups. Thanks again.
Impressive! Thanks!
Thanks for another great seminar. Probably best to stay away from sugars in general. However, this study does highlight how complex and unknown the workings of the human body actually are.
Thanks.
I think that the relation between fructose and glucose is much more easily understood when one remembers that sucrose is a disaccharide which normally contains one molecule of glucose, and one of fructose. Next to remember that fructose is ver much sweeter than glucose. Starches are entirely composed of glucose, so that splitting starches does not yield much sweetness. Whence high fructose corn syrup. Given that it is easy to understand that high fructose corn syrup is simply a way of yielding the most sweetness from the lowest amount of starch. The snag is that fructose must be entirely processed in the liver where it is converted at least partly into fat. I used to be a beekeeper and know that different honeys yields different levels of sweetness depending upon the ratio of glucose to fructose in them.
Thanks! Very helpful.
Mountain Dew and Dr Pepper are popular in N C, too. Especially among the "I want my caffeine cold in the morning and H*** no I am not drinking one of those frou-frou iced coffee drinks" croud. LOL
Thanks. So true.
Having lived in Lexington, and now just a few hours north, I am well acquainted with the Mountain Dew for breakfast phenomenon!
Thanks for video.
And I’m NOT feeling lucky, either.
Thanks!
Yeah, the evidence seems to be stacking up against refined carbs in general, with the important note that refined fructose and glucose may have different metabolism. Given how widespread glucose metabolism issues are, it seems important to get clarity on the differences.
For example, my favorite restaurant serves agave nectar sweetened sodas. They heavily advertise these sodas as low glycemic index, etc. That kills me 😆. While it seems true, that's because agave is *extremely* high in fructose, not sucrose or glucose, and that doesn't imply that it's all good. People like Lustig argue that this huge dose of liquid fructose is going to inflame the liver and potentially lead to liver insulin resistance.
New study just out last week saw great success in treating fatty liver in adolescents (!!): "In this study of adolescent boys with NAFLD, 8 weeks of provision of a diet low in free sugar content compared with usual diet resulted in significant improvement in hepatic steatosis."
A substantial portion of the boys on the low free sugar diet saw their fatty liver disease clear up within 8 weeks.
jamanetwork.com/journals/jama/article-abstract/2721179
Personally, while I think the case is building against fructose and refined carbs, and I don't avoid many fats (I consume plenty of olive oil, nuts, seeds, flax), I'm not yet jumping on the all fat, anti-carb train. My sense is that, for some, minimizing carbs is clearly the way to go. And also cutting out the sodas, crackers, white bread and pasta is probably advisable for most everyone. But, absent glucose metabolism issues, I'm not too scared of most whole food carb sources, things like whole oat groats, sweet potato, kiwi...
Thanks
Fructose goes directly to the liver, whereas the other sugars circulate in the blood until used or stored.
Thanks.
All three are bad. It's just that one may be less bad than the other two. I agree with you, Dr. Brewer. Avoid all three.
Yes. Thanks.
I always appreciate your work and John’s as well. I have some questions, based on Robert Lustig’s lectures. Number one, in a fasted state, why would fructose elevate glucose and insulin, since it contains no glucose? I would not expect it. There is only one place where we metabolize fructose, the liver with its GLUT5 receptor. It follows a different pathway than glucose, the same one as ethanol. It has a preliminary generation of ROS even before it hits the TGA cycle. And it does not convert to glycogen. It can generate lipids easily.
We do not know the background of the people involved. How much fat was already in their livers? And do we secrete triglycerides within the 120 minutes of the test? An additional category for a follow up study could be adding a cohort with a corresponding amount of ethanol. If that group would have similar elevations in CRP and triglycerides, then we may see that the fructose result is normal.
When we see elevations of glucose and insulin from glucose and sucrose (half glucose), then we would expect a normal response of elevation. But we do not know the general condition of the subjects, fat with IR or skinny with IR.
I have my bias as coming from a successful use of the Starch Solution over the past three years. I have altered that plan to add pulses to my plate once or twice a day when I have a high starch meal. It seems to be okay, but I have no data to share about my blood glucose levels. Perhaps I will add a meter to my growing list of hardware to track it better. I know that John and you have both individually tracked your own levels. My recent Kraft style oral glucose and insulin tolerance gave me a pattern A response, which was welcome news. I have just recently added a time restriction to my eating to fit within the 10 hour window suggested by Satchin Panda. I also have completed my fifth cycle of FMD. Net weight lost to date is 105 pounds down over three years.
Thanks again to you and John for bringing to light a lot of good ideas. I continue to love my potatoes, bread, and oats. And vegetables as well as whole fruit. I have wished my sugar treats a fond farewell. A quote from CS Lewis comes to mind, “A pleasure is not complete until it is remembered.”
Thanks for doing that hard work!
Very interesting observations
actually， I am pro fructose. Why people want add "sugar" to their food, cuz they want the sweetness. Fructose is 1.6 times "sweeter" then cane sugar(Sucrose), Glucose does not taste sweet at all. So to speak you achieve the same level of sweetness with a fraction of total amount of "sugar" with pure fructose. Control the total amount of intake of "sugar" is more important than what type of sugar, fructose, sucrose, are way better than "industry sweetener".
I gave up thinking about it. I don't touch fruit, sugar, bread, rice, pasta, sauces - just meat, fat and vege. At least my HbA1c , Cholesterol figures, BMI are good. not so much the other stuff though lol
Thanks.
Doctor why do I feel my feet getting numb and prickly feeling and owe by the way there is a big sale of Mountain Dew and Pepsi products going on right now!LOL!!!
Ouch! Thanks.
Thank you for your efforts and info.
Thanks for the feedback.
Makes perfect sense if you look at history of early man. Fruits are designed to fatten up humans for the long winter when food is scarce.... for hundreds of thousands of years, perhaps up to 2 million years. Similar to bears that gorge on fruits before hibernation. The liver metabolizes fructose into fat storage rather quickly, unlike glucose.
Thanks
I really like fruit. But, I have to admit that over my life time , the level of sweetness in most of the fruit I eat has gone through the roof.
Clearly, refined carb/sugar are very bad. But, I guess, at the end of the day, sugar is sugar. And should be kept at the lowest levels possible until more research indicates otherwise.
QUESTION. Are whole Apples and Oranges going to give you the bad effects of fructose or does the fiber help protect you from the undesirable effects ?
The fiber does slow it down. But eat them & check your blood sugar. You’ll see that the fiber isn’t an antidote.
Sugars bound to plant fiber release into the blood much more slowly than say sugar from orange juice. However everyone seems to have the idea that fruit is natural and therefore healthy. Undomesticated bananas are hard and fibrous and contain seeds, for instance. For almost all of human history we didn't eat much fructose, now we've cultivated bananas that contain two or three teaspoons of fructose.
outbackslim so true. Thanks!
The Mt Dew Mafia is going to Report this video to TH-cam...
Bad news!
Could it be that because fructose does not go straight into the blood stream and can only be processed in the liver and stored as fat, according to Dr Lustig?
Could be. Lusting is a sharp guy.
Have you reviewed Dr. Luc Tappy's fructose study?
I took a brief look last night. And I’m doing a lot more work on fructose today - a couple of hours. It will be some time before the fructose videos come out.
Better stop eating sweet fruits for now.
Yes thanks