The Horrifying Forgotten Encephalitis Lethargica Pandemic

แชร์
ฝัง
  • เผยแพร่เมื่อ 21 มี.ค. 2020
  • In the video today, we're looking at the relatively modern forgotten pandemic that killed over a million people, left tens of thousands more having lost the will to move or express themselves, and yet was barely newsworthy at the time it was on its murderous rampage for reasons we'll get into today.
    If you'd like the text version or references, you can find those here: www.todayifoundout.com/index.p...

ความคิดเห็น • 803

  • @beagleissleeping5359
    @beagleissleeping5359 4 ปีที่แล้ว +99

    I remember a scene from "Awakenings" where a patient asked where her husband was. They told her he'd filed for a divorce several years previous. She sat in silence a moment then exclaimed, "THANK GOD!"🤣🤣

    • @cbrite
      @cbrite 4 ปีที่แล้ว +5

      I immediately thought about the movie right when he described the disease in the beginning.

    • @randallhesse5011
      @randallhesse5011 ปีที่แล้ว +1

      L-methyl levadopa has such horrible bioavailabiliy. (It's like curcumin in that way). I was thinking that perhaps that might be the real reason as to why those people in the awakenings reverted. I don't know. It's something to ponder about.

  • @BeckyFrame
    @BeckyFrame 4 ปีที่แล้ว +16

    My grandpa had this during the 1920s outbreak. He was in the percentage that mostly recovered but suffered long-lasting effects.

  • @bbutc
    @bbutc 4 ปีที่แล้ว +318

    The fact that victims were able to 'wake up' when treated with certain drugs proves that the part of the brain responsible for consciousness had not been destroyed but somehow disconnected. I think this gives hope that a cure will be found in the future - probably just needs a lot more funding for re-search.

    • @Sentient.A.I.
      @Sentient.A.I. 4 ปีที่แล้ว +25

      Cured by l-dopamine. But they fell back asleep once they became tolerant. I wonder if they tried different things with the L dopa. Like letting tolerance fall off and re awakening them with it again. Or using massive doses to outweigh the tolerance. I thought they used L-dopa for some other syndromes. Surely if L-dopa was effective why not try amphetamines? Or A re-uptake inhibitor for dopamine? I guess the majority of these folks have passed on by now but now we have certain adhd and wakefulness drugs that can be easily tolerated and are effective on the dopamine systems. Seems like it would be an easy treatment these days.

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +36

      Look into locked in syndrome. I was extremely close to someone it happened to and watched him literally loose the will to live and eventually pass after 15-16 years of only being able to move or make a vocal noise from a reaction of something he found extremely funny/painful/arousing. I think his memory and personality being intact made it harder for him to keep hope because you could not bullshit him that everything would eventually be back to normal like the drs would tell you to act like you believed around him to keep his spirits up.

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +26

      He passed almost 4 years ago now. I know they were getting close not to fixing it but at least making communication and sort of controlling the wheelchair, which really would have changed stuff and I think he'd still be alive today with just those extra couple of things. I can't imagine almost 2 decades of having your thoughts ideas and impulses running almost normal but can't speak/move/do anything about any of it.

    • @pierrecurie
      @pierrecurie 4 ปีที่แล้ว +31

      @@CarInMyAss Locked in syndrome is much worse, since as you pointed out, the patient is actively conscious. They want to do things, but can't because the nerves don't work. Here, it's the opposite - the nerves work, but the mind itself has shut down.

    • @thegreyman1575
      @thegreyman1575 4 ปีที่แล้ว +7

      pierrecurie
      I just think it’s insane to see you guys talking about this in such an effective manner. Good job guys! Keep at it with the theorizing, because nobody else’s gonna do it

  • @perrydowd9285
    @perrydowd9285 4 ปีที่แล้ว +50

    Encephalitis Lethagica still affects 3-4 people every year in Australia. The experts are still unable to find a cause beyond some vague association with influenza or streptococcus (strep is a common secondary infection of the flu).
    An excellent book documenting the epidemic is "Asleep", by Molly Caldwell Crosby.

    • @OtakuUnitedStudio
      @OtakuUnitedStudio 4 ปีที่แล้ว +2

      Streptococcus and staphylococcus can cause meningitis if they make it to the nervous system. It's probably cause by damage from infected neurons.

    • @koditv551
      @koditv551 4 ปีที่แล้ว +4

      This sounds similar to CFS/ME which can be triggered by a viral infection, one can have slow onset as well. Evidence is mounting to support an abnormal immune response in the brain causing neuroinflammation, which in turn causes sickness behaviour and perturbs all of the major systems in the brain, CNS, SNS, HPA axis, fight flight freeze response, etc. Severe cases are bed bound. It is like the immune system in the brain turns on but never turns off. Research is finding similarities between CFS/ME and MS, which is caused by neuroinflammation due to an abnormal immune system in the brain. There are treatments that help control the immune system in the brain, unfortunately they don't help everyone and good luck finding a doctor that is willing to help

    • @koditv551
      @koditv551 4 ปีที่แล้ว

      @Barbara MulvaneyCFS - chronic fatigue syndrome , ME - myalgic encephalomyelitis. The US uses CFS and the UK uses ME. Neither one is a good name and they have been trying to merge the two. A better name is SEID - systemic exertion intolerance disease. I have read that CFS is like a cousin to MS. They have very similar symptoms as well. The best place for info on ME/CFS that I have found is healthrising.org , but that won't help you with MS. An interesting drug to look into is LDN - low dose naltreone, a good place for info on it is ldnresearchtrust.org.

  • @SomePeculiarities
    @SomePeculiarities 4 ปีที่แล้ว +11

    The book "Awakenings" is actually a non-fiction collection of case studies by their neurologist. And the outcome of the drug was even more cruel than just developing tolerance - many of the patients improved to the state of near-normalcy within weeks but then started experiencing side-effects so severe and extreme that some willingly decided to stop taking the drug and return to their catatonic states

    • @capricorn8426
      @capricorn8426 2 ปีที่แล้ว

      Actually the movie did show some of the side effects to leonard, he experienced extreme emotions, anger. I'm sure it was way worse

  • @ErdrickHero
    @ErdrickHero 4 ปีที่แล้ว +88

    I've never read/seen/heard of "Awakenings", but that tragedy reminds me of "Flowers for Algernon", about a mentally handicapped man, who, through a new experimental treatment, gained high intelligence for a short time before slowly regressing back to his handicapped state.

    • @pattihawks8514
      @pattihawks8514 4 ปีที่แล้ว +1

      Erdrick The Hero
      Same.

    • @imzadi83fanvids7
      @imzadi83fanvids7 4 ปีที่แล้ว +8

      If I recall the ending was worse then just "regressing" but it's been awhile since I've read that story.

    • @ErdrickHero
      @ErdrickHero 4 ปีที่แล้ว +1

      @@imzadi83fanvids7 He may have died at the end. It's been over a decade since I read the story.

    • @imzadi83fanvids7
      @imzadi83fanvids7 4 ปีที่แล้ว +2

      @@ErdrickHero I think he did but I wasn't sure. I just remember them finding the mouse dead in the box.

    • @dlee645
      @dlee645 4 ปีที่แล้ว +11

      Erdrick The Hero Flowers for Algernon is a wonderful and heartbreaking short story by Daniel Keyes and first published in 1959. It was a Hugo award winner in 1960. It has been adapted for the stage and also into an Academy Award winning movie called “Charly” starring, I believe, Cliff Robertson.
      I’ve never seen the movie, but I highly recommend reading the short story. Be warned, it is a heartbreaker.

  • @MarielaQue
    @MarielaQue 4 ปีที่แล้ว +190

    Finally something positive and heart warming

    • @jenniferryersejones9876
      @jenniferryersejones9876 4 ปีที่แล้ว +4

      Heh, heh!

    • @rustyaxelrod
      @rustyaxelrod 4 ปีที่แล้ว +10

      Sarcasm, one of my favorite forms of coping...

    • @workhardism
      @workhardism 4 ปีที่แล้ว +5

      That comment has that certain, subtle, sarcasm that i like in a good comment. Your a funny one aren't you? LoL.

    • @marionziemke3784
      @marionziemke3784 4 หลายเดือนก่อน

      Hugs 🤗

  • @AnthonyMonaghan
    @AnthonyMonaghan 4 ปีที่แล้ว +246

    The first man to thoroughly document his own impressive facial hair.

    • @rosevelvet4357
      @rosevelvet4357 4 ปีที่แล้ว +18

      Anthony Monaghan he might be the first but not the last. Simon has 5 channels he documents his facial hair on

    • @AngryPieMan
      @AngryPieMan 4 ปีที่แล้ว +4

      Rhett from Good Mythical Morning also has an impressive beard and documentation thereof. He's almost a mountain man now.

  • @stephenwright8824
    @stephenwright8824 4 ปีที่แล้ว +163

    FWIW *AWAKENINGS* was a fantastic movie. RIP Robin Williams.

    • @pattihawks8514
      @pattihawks8514 4 ปีที่แล้ว +2

      Stephen Wright yes!

    • @jancal9285
      @jancal9285 4 ปีที่แล้ว +17

      Equally fantastic is the book’s author, Oliver Sacks, the *brilliant* neurologist who worked with these patients and was inspired to try L-dopa. RIP, Oliver Sacks 💐

    • @jlkraus2
      @jlkraus2 4 ปีที่แล้ว +6

      the man who mistook his hife for a hat

    • @jefferyepstein9210
      @jefferyepstein9210 4 ปีที่แล้ว +3

      Stephen Wright
      It was a great example of his amazing range of talent

    • @ginnyjollykidd
      @ginnyjollykidd 4 ปีที่แล้ว +5

      It was. And it was thoroughly puzzling, triumphant, and tragic in best proportion.

  • @LunaHarp91
    @LunaHarp91 4 ปีที่แล้ว +127

    Sounds like being catatonic, times 1000. When my sister was sick with lupus, she went into a state like that. Twice. It was one of the saddest & most painful things I've ever seen someone else go through. She's gone now, she's free.
    Edit: my comment was made before you actually said "catatonic state".

    • @itsthatsebguy93
      @itsthatsebguy93 4 ปีที่แล้ว +6

      Thats terrible man.

    • @adrianna5378
      @adrianna5378 4 ปีที่แล้ว +7

      Sorry for you loss. I lost my mom a few years ago and she went into a comma.

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +33

      Tl:Dr for this whole thing , mentally aware but locked in and mute regardless of what illness caused it it one of the worst ways to live/die and watch someone live/die while you can't do anything no matter how much you love and care.
      I had my closest friend get what's commonly referred to as "locked in syndrome" which is rare but back in 1999 there wasn't much info on it for a 15 yr old to find. It's hard to watch someone you love locked in like that (hate it for you but glad she's free original commenter) and only rarely something you say or do gets a laugh or cry with some involuntary muscle spasms/movement. He's finally at peace also. Hated to see him go but everyone but me, a couple very close friends, and his family had all given up years ago (so many people faked caring or pretended to care way more either feeling obligated to/virtue signaling/ or thought it made them seem sensitive and sincere) and he had to watch us finish high school, me get married, have kids, get divorced/remarried etc. Basically some of the most defining years of a persons life he was just a spectator for. Had perfect memory of everything, could hear see and think, just no talk and no move. It's hard to watch and it killed me but i think i couldn't live with the guilt if i didn't stick around and remember b days, keep up with the music and stuff we liked, sit and play through games we would have played together to help him feel like he experienced them etc. Always got 2 copies of every album so he could have one, ya know trying to be a good friend like i think I'd want if the roles reversed. Now that I've seen it, any kind of locked in or mental prison type thing where you still have a concept of time and are as aware as you'd normally be has to be one of the worst tortures there is. Even communication was eyes look up for yes down for no with a letter and number chart. Had to be horrible to try and express yourself that way. He brought some attention to the condition though, i think it was scientific American (magazine) had a big article on it in 2004-2006 ish about all the experimental treatment and the different ways his family tried to communicate with him and how we felt like we were so close to getting him to speak again with some of the laughter reaction i could get out of him (i was kinda his jester since that was the first way (almost the only way ever after the accident) he ever vocally and physically responded to anything) blah im rambling and off topic since I'm far from sober and it's almost his bday and that gets me emotional every year since he died or was freed from what may have just been daily mental hell, depending on when i asked him I'd get different answers or amounts of motivation to improve. I was supposed to be in the seat he was in that night but got last minute grounded. Took a long time to not think about if I'd have done one thing different the car wouldn't have been there for the accident from the extra time to pick me up or all the things that could have been different over one little decision. Ok I'm done. Sorry again, this just all reminded me of this and happened to be this time of year and i haven't spoke about in in a long time.

    • @SafetySpooon
      @SafetySpooon 4 ปีที่แล้ว +6

      I pray the memory of your beloved sister is a blessing to you

    • @LunaHarp91
      @LunaHarp91 4 ปีที่แล้ว +4

      Thank you all.

  • @surprisedchar2458
    @surprisedchar2458 4 ปีที่แล้ว +49

    Some guy in 1924: “Man my throat sure does hurt.”
    His body: “We’ve activated the Winter Contingency.”

  • @Pining_for_the_fjords
    @Pining_for_the_fjords 4 ปีที่แล้ว +339

    I heard that a common symptom of this disease was an irrational compulsion to buy toilet roll.

    • @mbgrafix
      @mbgrafix 4 ปีที่แล้ว +3

      😏Hmmmm...yes!...and that one of the _surest_ ways of catching it was to avidly avoid all social contact!

    • @lovelydolltime8006
      @lovelydolltime8006 4 ปีที่แล้ว +3

      I've gotta buy a 6 foot long stick.

    • @virkgale
      @virkgale 4 ปีที่แล้ว +1

      I heard it started in Australia before spreading across the world, and if not the symptom of an irrational compulsion to buy toilet roll was definitely first reported in Australia ...

    • @vantastic9367
      @vantastic9367 4 ปีที่แล้ว

      😂😂 yes

    • @workhardism
      @workhardism 4 ปีที่แล้ว

      Along with a compulsion to socially distance yourself 6 feet from everyone.

  • @CujoHyer
    @CujoHyer 4 ปีที่แล้ว +115

    Quite often this channel has a weird Macabre undertone.
    And I love it.

    • @athenacykes3486
      @athenacykes3486 4 ปีที่แล้ว +6

      @@BenGearig but none of those words are big...or complicated?

    • @ItsXanPan
      @ItsXanPan 4 ปีที่แล้ว +2

      Benjamin Gearig I cant think of a simpler or more commonly used synonym for macabre so I don’t know what you expected them to say instead.

    • @CujoHyer
      @CujoHyer 4 ปีที่แล้ว +2

      @@BenGearig I capitalized it on purpose, becuase it was the point of what I was saying.
      I don't really care if that's common place in writing rules or not, because this is TH-cam's shitty comment section.
      With strangely aggressive people on it, like yourself.

    • @mrsx7944
      @mrsx7944 3 ปีที่แล้ว

      @@BenGearig "macabre" isn't a big boy word. I used that word in high school in a term paper.

    • @mrsx7944
      @mrsx7944 3 ปีที่แล้ว

      @@CujoHyer I don't get it either. I consider "macabre" a pretty basic and common word. But I also read a lot of Stephen King. 🤷‍♀️

  • @bilindalaw-morley161
    @bilindalaw-morley161 4 ปีที่แล้ว +17

    “Thousands of living paperweights”? I had to replay three time to be sure that,yup, you did actually say it

    • @kazbronkitty
      @kazbronkitty 4 ปีที่แล้ว +4

      Bilinda Law-Morley I thought that phrasing was a little insensitive tbh

  • @Serai3
    @Serai3 4 ปีที่แล้ว +28

    And by the way, the patients were NOT all comatose or frozen. If you read the book by Oliver Sacks, you'd see that the symptoms ranged from comatose to ambulatory, silent to loquacious, frozen to hyperkinetic. The connecting factor was in how they'd come to their conditions, and the fact that all their symptoms made normal life impossible.

  • @pedrosmith221
    @pedrosmith221 4 ปีที่แล้ว +199

    "A virus that causes you to lose the will to express yourself".. I thought you were going to talk about youTube demonetization

    • @Barbarossa19
      @Barbarossa19 4 ปีที่แล้ว +4

      @spiro And you're here because...?

    • @RavenMacy
      @RavenMacy 4 ปีที่แล้ว +3

      @spiro I'm with mr redbeard here , why are you here hipster ?

    • @TS_Mind_Swept
      @TS_Mind_Swept 4 ปีที่แล้ว

      I thought he was going to talk about depression or one of those other many psychological afflictions

    • @mybld8969
      @mybld8969 4 ปีที่แล้ว +1

      @spiro whats wrong about what is said though

    • @philbyd
      @philbyd 4 ปีที่แล้ว

      Light House 😂😂😂

  • @bcabmac
    @bcabmac 4 ปีที่แล้ว +14

    My understanding was patients in the 20s and 30s and several documented case in the 40s through 50s presented with the disease. A common link among many of them had also been exposure to polio. What is known is that this form of encephalitis is believed to be associated with more than one pathogenic viruse or infection in susceptible people. It is also similar but not neccessary related to symptomology of prion disease in it's most severe manifestation. What is concerning is that like a volcano, certain acquired pathogenic diseases are cyclical through their evolution of similar or related mutating strains and often change the physiological immuno response to secondary infectious diseases by altering the markers that would normally protect cells from attachment and invasion in the host. If that holds true, we could be facing a similar epidemic of encephalitis lethargica right behind the current corona pandemic. With the possibility that one prior to the other may have created an immunological response in hosts in a given population that allowed the virus to propagate in a unique fashion in susceptible individuals. In other words it may take one to have the other. And we could be on the verge of repeating history.

    • @AmberAmber
      @AmberAmber 4 ปีที่แล้ว +7

      I was thinking that too - (and yeah - like how chicken pox begets shingles, & ocular herpes simplex can beget bell's palsy, & herpetic encephalitis... possibly Pityriasis Rosea)

    • @heide-raquelfuss5580
      @heide-raquelfuss5580 4 ปีที่แล้ว +2

      I think you are right, unfortunately.
      Bless you

  • @doobsdemons
    @doobsdemons 4 ปีที่แล้ว +72

    Awakenings..Robin Williams

    • @thisisavivistanaccount7866
      @thisisavivistanaccount7866 4 ปีที่แล้ว +1

      Matthew Dubea I’ve seen that movie it was good

    • @robertpalumbo9089
      @robertpalumbo9089 4 ปีที่แล้ว

      Yes

    • @marccolten9801
      @marccolten9801 4 ปีที่แล้ว +10

      Read Oliver Sacks book. The movie was almost completely inaccurate and very cleaned up. For example, it was not a mystery that the victims were alert. The character played by DeNiro tapped out messages. Also when he was brought out of his paralysis it was pretty ugly as all of his pent up emotions and sexual frustrations were let loose. Real life is a lot sadder andore horrifying than a Hollywood movie.

    • @Serai3
      @Serai3 4 ปีที่แล้ว +2

      I can't believe Oliver Sacks is not mentioned anywhere in this as the doctor who came up with the medication.

    • @dickJohnsonpeter
      @dickJohnsonpeter 4 ปีที่แล้ว

      6:57 he said that. But he pinned this comment so it looks like even *he* didn't notice he said it.

  • @heatherk841
    @heatherk841 4 ปีที่แล้ว +18

    You guys are awesome at finding the craziest, entertaining, and wonderful TRUTH! Keep on truckin

    • @kaintshine
      @kaintshine 4 ปีที่แล้ว +1

      Make the truth viral. I can look up and confirm the facts, like we all should smh

  • @YouSoRusso
    @YouSoRusso 4 ปีที่แล้ว +14

    I love your humour, makes me smile. Thanks for that in this weirdest of times.

  • @arieldiaz4607
    @arieldiaz4607 4 ปีที่แล้ว +2

    There was a movie about this called “Awakenings.” I’ve never cried so hard at a movie.

  • @jeffreym68
    @jeffreym68 4 ปีที่แล้ว +2

    That sounds like about the worst fate I can imagine and my partner died this weekend. Those poor people and their families must have suffered terribly. It's scary as well that we don't have a solution for this and so many other diseases that don't effect "enough" people to get research funding.

  • @petemagnuson7357
    @petemagnuson7357 4 ปีที่แล้ว +17

    Well, that's an upsetting idea.

  • @PhilBesch
    @PhilBesch 4 ปีที่แล้ว

    The ending of this was hilarious bro! Watching you try to hold it together was hysterical. I will definitely like and share!

  • @PokettoManStar
    @PokettoManStar 4 ปีที่แล้ว +84

    How many plagues were forgotten? This one better not be. We should all make an effort to remember this moment, and teach the next generation.

    • @drshoe8744
      @drshoe8744 4 ปีที่แล้ว +2

      #ChineseVirusesMatter

    • @70mjc
      @70mjc 4 ปีที่แล้ว +1

      Poketto that a bunch of idiots believed rich idiots resulting in the rich idiots taking all of the money?

    • @70mjc
      @70mjc 4 ปีที่แล้ว +5

      Xeno Phon we can’t single out a viral variant until we can determine the major virus itself.....

    • @wrongsalvation8904
      @wrongsalvation8904 4 ปีที่แล้ว +11

      There are many pandemic diseases that we don't talk about. We only remember or talk about the ones that are in our history books. We remember 1918 Spanish flu, we remember the bubonic plague and pneumonic plague and even some of us remember the Justinian plague. People outside the US probably do not remember yellow fever, scarlet fever or any of its like. That is why it is best to educate yourself as much as you can with facts. They don't always teach us everything in school.

    • @BigMobe
      @BigMobe 4 ปีที่แล้ว +2

      That one roll of butt paper I kept in a water tight bag in the back of my Jeep for many years might actually get used.

  • @calisahardy4845
    @calisahardy4845 4 ปีที่แล้ว

    😌 I'm enjoying having more of you, Simon. Even if you are bringing me stories of cheerful outbreaks.

  • @Serai3
    @Serai3 4 ปีที่แล้ว +3

    I can't believe you didn't mention Oliver Sacks, the doctor who came up with L-DOPA, the medication that brought them out of their condition briefly. He wrote a brilliant book, _Awakenings,_ that got made into that movie. Fascinating stuff, a deep dive into the disease and its effects. This is not as forgotten or as misunderstood a disease as this video claims.

  • @jacobhuff3748
    @jacobhuff3748 4 ปีที่แล้ว +32

    This or the Spanish Flu? I'll go with the Spanish Flu;sure my young and potent immune system may over react and kill me but dying as a an immobile and mute invalid is scarier.

    • @carbon1255
      @carbon1255 4 ปีที่แล้ว +3

      Coronavirus also causes the same cytokene response. This is what kills young people that get it.

  • @CalumCarlyle
    @CalumCarlyle 4 ปีที่แล้ว +12

    All readers of Neil Gaiman's Sandman will be familiar with this disease, since it is central to the plot of the first story arc, called "Preludes and Nocturnes".

    • @lissaquon607
      @lissaquon607 4 ปีที่แล้ว

      I was thinking "oh hey this sounds familiar "

  • @racesmith3075
    @racesmith3075 4 ปีที่แล้ว

    Simon! You are one of my favorite happy places! 🥰
    I love your humor., thanks so much

  • @michaelball93
    @michaelball93 4 ปีที่แล้ว +5

    The world outside may be crashing and burning but we'll all still hold on as Mr. Whistler tells his uplifting stories to see us through the apocalypse.

    • @Johnny-tq9no
      @Johnny-tq9no 4 ปีที่แล้ว

      Seems pretty much normal to me

  • @maryperez6808
    @maryperez6808 2 ปีที่แล้ว

    I enjoyed it!! Well done.

  • @joeyr7294
    @joeyr7294 4 ปีที่แล้ว +1

    Lmao the exposure line at the end was great! Keep up the hard work man and stay safe!

  • @dianafossi1295
    @dianafossi1295 4 ปีที่แล้ว +8

    This left me with an unsettling feeling but regardless it was a great video!

  • @kaarlimakela3413
    @kaarlimakela3413 4 ปีที่แล้ว +35

    It would be a dark age indeed that forgets Robin Williams and all his movies ... or DeNiro either!

  • @annamcfadden5485
    @annamcfadden5485 4 ปีที่แล้ว

    Always enjoy ur videos

  • @RBuckminsterFuller
    @RBuckminsterFuller 4 ปีที่แล้ว +4

    Very famous case taught in medical schools. Awakenings is an amazing movie.

  • @TheRealGuywithoutaMustache
    @TheRealGuywithoutaMustache 4 ปีที่แล้ว +157

    If you can't pronounce it, it's probably bad for you

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +3

      Which is why it's no biggie. Just a bunch of mainstream news fluff

    • @zzdesolatezz
      @zzdesolatezz 4 ปีที่แล้ว +6

      But, I can pronounce it... ☹

    • @dafttool
      @dafttool 4 ปีที่แล้ว +8

      Just Some Guy without a Mustache I’ve been told I often mispronounce “birthday,” & those are certainly hazardous for your health

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +2

      I can't pronounce or spell dorctors orface. I hate getting sick 😷

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว

      The emnergenty roam is just as bad.

  • @bxdanny
    @bxdanny 4 ปีที่แล้ว +26

    Lost "the will" to move or express themselves? Wouldn't it be better to say lost the ability? Did the people not try, unsuccessfully, to do so? When the people were temporarily cured (or made less ill) with L-dopa, didn't anyone ask them what they had experienced? Were they aware of their surroundings?

    • @Shuker8964
      @Shuker8964 4 ปีที่แล้ว +10

      Yes, according to the book Awakenings by Oliver Sacks, the patients experienced time differently than others. Some describing it as being under the influence of very strong gravity. They might move but they were extremely slow, think of taking 4 hours for your hand to reach your nose to scratch it

    • @ASmith-jn7kf
      @ASmith-jn7kf 4 ปีที่แล้ว +8

      Losing the will does not mean it is voluntary nor that the person who lost it was happy about it.

    • @rhondabonner9856
      @rhondabonner9856 4 ปีที่แล้ว

      @Mr. & Mrs Smith according to the movie Awakenings patients did catch a ball thrown at them. One of the doctors first diiscoveries.

    • @heide-raquelfuss5580
      @heide-raquelfuss5580 4 ปีที่แล้ว

      @Mr. & Mrs Smith
      You explaned well.
      It is indeed scary as hell.
      But super interresting how biology/ chemistry works.
      But devastating scary.
      Bless you

  • @ladytron9188
    @ladytron9188 4 ปีที่แล้ว

    Great humour ,well written and brilliant narration.Mutch needed laugh .Thanks👏👏👏👏👏👏

  • @CarInMyAss
    @CarInMyAss 4 ปีที่แล้ว

    This is a good one. Information that's helpful/interesting and most people don't know

  • @nico7654321
    @nico7654321 4 ปีที่แล้ว +18

    Encephalitis lethargica... 🤔 I think I have the name for my new melodic symphonic power metal band

    • @randallteagancaudle5308
      @randallteagancaudle5308 4 ปีที่แล้ว +1

      Do it! Write lyrics that are relatable such mental conditions. Of course, be careful that the style and lyrics are not comparable to another popular metal group, else Lars may come after you!

    • @katyungodly
      @katyungodly 4 ปีที่แล้ว +1

      Nicolas Cabrales sounds more like a death metal/slam band name haha

    • @MetalTrabant
      @MetalTrabant 3 ปีที่แล้ว

      It sounds more like a death metal/grindcore name :)

  • @coffeecat086
    @coffeecat086 5 หลายเดือนก่อน

    Dr. Sacks was a gift to humankind. He made those of us with disabilities seem and heard. He was empathetic and what doctors really should try to emulate. He see us as human, and even though he spoke of how neurologically we are different, he didn’t see it as a defect, but just another difference in how we live our lives. He is missed.

  • @loungelizard836
    @loungelizard836 4 ปีที่แล้ว

    Smashed. Absolutely smashing!

  • @Heinskitz
    @Heinskitz 4 ปีที่แล้ว +1

    Absolutely terrifying. Many thanks.

  • @gr8rw8r
    @gr8rw8r 4 ปีที่แล้ว

    I thoroughly enjoyed this video

  • @fortifyjoy
    @fortifyjoy 4 ปีที่แล้ว

    unrelated to the video BUT Simon your beard looks phenomenal, the coloring and everything looks carefully crafted, and it looks very well-kept, very good look for you
    thank you everyone at TIFO for the video as well but I thought I'd also put in a personal note for the host :)

  • @bensalazar4561
    @bensalazar4561 4 ปีที่แล้ว

    Very interesting and scary thanks Simon 😩

  • @gardyloo3093
    @gardyloo3093 4 ปีที่แล้ว

    I am completely onsessing about this now. Thanks.

  • @Kristers_K
    @Kristers_K 4 ปีที่แล้ว +9

    You're really rockin' with that beard :O

  • @brandentempelmeyer4785
    @brandentempelmeyer4785 4 ปีที่แล้ว +3

    Funny part is I shared it to my Facebook just before you mentioned sharing it on social media and going viral

  • @dakotacook4407
    @dakotacook4407 4 ปีที่แล้ว

    The end there made me think I'd somehow switched to a business blaze video lol. Sadly, I've already watched the ones you have out. In a few days. In other words, it's a fantastic channel. Since I came across this channel, I've pretty much only been watching it, geographics, biographics, toptenz, and soon I'll be burning through your politics channel as well.

  • @super_slo
    @super_slo 4 ปีที่แล้ว +2

    🤣🤣🤣😂😂 that plug at the end! Well played sir!

  • @puellanivis
    @puellanivis 4 ปีที่แล้ว +1

    I think I recall reading that with at least one patient, there was a fire, and they were able to get up and out of the fire, but then reverted to “comatose” once safe. Again, pointing to the motivation portion of the brain being interfered with. i.e. given sufficient cause, they could save themselves, but otherwise physiologically cannot get up sufficient motivation to even feed themselves. I think it poses interesting data for people with depression, as it is known that depression affects the part of the brain that accounts for motivation as well. We’re not being “lazy” when we don’t do anything, if that were true, we would still do things that we find fun. But rather we physiologically cannot build up the motivation to do things.

  • @curiousman1672
    @curiousman1672 4 ปีที่แล้ว +1

    Related story. Fifty years ago, my best friend in kindergarten, Billy Jenisson, didn't show up for school anymore. A straight blond haired farm lad, seemed to just disappear. Several years later I saw a new kid, with curly, black hair (something you don't see in Scandinavian children in the Midwest). I was told his name was Billy Jenisson, the same one. He was bitten by an encephalitis carrying mosquito, leaving him mentally about 3 years old. No one could explain the change in his hair. We're approaching 60 years old, and he still lives on the farm, cared for by a sibling.

  • @1701spacecadet
    @1701spacecadet 4 ปีที่แล้ว +1

    And here's Simon to make our weekend even more cheerful! 🤔

  • @ataphelicopter5734
    @ataphelicopter5734 3 ปีที่แล้ว +1

    It’s 40 minutes past midnight, and as he said “suddenly fall asleep” I nearly passed out from tiredness

  • @jasonwojtkiewicz4340
    @jasonwojtkiewicz4340 4 ปีที่แล้ว +1

    Damned if I dont say it... I DID enjoy this video Simon! Keep up the great work, please. 🙃

  • @nin315
    @nin315 4 ปีที่แล้ว +6

    Great, now I have a new thing I can be paranoid about possibly getting later in life when I lay in bed at night. 😂

  • @diyeana
    @diyeana 4 ปีที่แล้ว

    Oh my gaaaaaawd!!!
    Yes, Simon, I enjoyed this very much. I'll enjoy it in my nightmare tonight too. Thank you.

  • @sophierobinson2738
    @sophierobinson2738 4 ปีที่แล้ว

    Very interesting! There was a young patient at the mental hospital where my father worked who had the hyperkinetic form. She had been quite intelligent before the illness, but was reduced to somewhat child-like behavior.

  • @OdinOfficialEmcee
    @OdinOfficialEmcee 4 ปีที่แล้ว +27

    The description of what this illness could do made me think of this:
    "Darkness imprisoning me
    All that I see
    Absolute horror
    I cannot live
    I cannot die
    Trapped in myself
    Body my holding cell" - One, Metallica

    • @plants_before_people5329
      @plants_before_people5329 4 ปีที่แล้ว

      Amazing song

    • @plants_before_people5329
      @plants_before_people5329 4 ปีที่แล้ว +4

      @alan wake it's actually about war since there's sounds of gunshots and helicopters in the song. Plus the instruments are like a gun firing rounds

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +3

      Locked in syndrome really is like that just worse than anyone of us can imagine because once you have it expressing yourself like this is damn near impossible. (My closest friend [damn near brother] passed from this [complications from it not the actual locked in part] several years ago so idk what advances have been made. Hopefully it's different now or soon.)

    • @stikcler
      @stikcler 4 ปีที่แล้ว

      Johnny Got His Gun by Dalton Trumbo
      Check it out
      en.wikipedia.org/wiki/Johnny_Got_His_Gun#Adaptations

    • @katyungodly
      @katyungodly 4 ปีที่แล้ว +1

      alan wake no, it is based on a soldier losing his sight, hearing, arms, and legs to a landmine. This is clearly stated in the lyrics and the fact that the opening sound byte is helicopters, gunshots, and soldiers moving on the battlefield.
      “Landmine has taken my sight
      Taken my speech
      Taken my hearing
      Taken my arms
      Taken my legs
      Taken my soul
      Left me with life in hell”

  • @rachelatwood9555
    @rachelatwood9555 4 ปีที่แล้ว +1

    I binged on a lot of "Business Blaze" videos recently in which Simon lets loose & doesn't DGAF, so his relative professionalism here is striking. I can't be the only one to recognize this...

  • @queencobra1507
    @queencobra1507 4 ปีที่แล้ว

    This was awesome.

  • @adrigl3371
    @adrigl3371 4 ปีที่แล้ว +6

    Kinda reminds me of an SCP, a group of butterfly that makes you lose interest in stuff, if you are exposed enough you lose the will to do anything.

  • @dahlilance6087
    @dahlilance6087 4 ปีที่แล้ว +1

    I watched a documentary about this when I was a child and it terrified me.

  • @stackflow343
    @stackflow343 4 ปีที่แล้ว

    Bro really diggin the beard, it wears you well!

  • @cobalius
    @cobalius 4 ปีที่แล้ว

    I like this video. The tiny music in the background and his speaking skills are really some nice stuff. Oh and the topic is okay xD

  • @skyden24195
    @skyden24195 4 ปีที่แล้ว +3

    Smashing that "like" button because of Simon's uncertainty of how to end this video.

  • @geektome4781
    @geektome4781 4 ปีที่แล้ว +13

    The description in the thumbnail (“virus”) is wrong if, as he states in the video, the condition was caused by a bacteria.

    • @frozenjune83
      @frozenjune83 4 ปีที่แล้ว +6

      I was looking for a comment about this before typing my own.

    • @CarInMyAss
      @CarInMyAss 4 ปีที่แล้ว +1

      Some similar things (extremely similar) can be brought on by strokes and shit after car accidents too.

    • @katyungodly
      @katyungodly 4 ปีที่แล้ว +2

      They’re exploiting the algorithm/clickbaiting due to the pandemic.

  • @raindancer6111
    @raindancer6111 4 ปีที่แล้ว

    My uncle contracted this as a young child in the 20s. He survived until about his late 30s.
    He could move and communicate although with some disability. He would however occasionally freeze. This freezing always took a similar posture. My dad said it looked like he was looking over his shoulder at a corner of the ceiling. He was also prone to temper tantrums and even as a child could throw a grown man across the room. Doctors actually committed him to an asylum but my grandmother wouldn't let him be taken. He lived at home until he died in the late 50s.

  • @JesusLovesYouPerfectly
    @JesusLovesYouPerfectly 4 ปีที่แล้ว +2

    as a suggestion: i think after videos like this, you could say " i hope you found this video educational " i think that would fit much better because whether a person liked it or not, they do still learn something either way.

  • @kudowsstudio
    @kudowsstudio ปีที่แล้ว

    You sir are a LEGEND

  • @80brax04
    @80brax04 4 ปีที่แล้ว +1

    I caught encephalomyelitis when I was 15 and I woke up completely paralyzed and on a ventilator.The only thing I could do for the first two month was blink,cry, and scream in my head. Once they took me off the vent to see if I could cough and breathe on my own all I did was beg them to kill me... non-stop, until they sedated me and I woke back up on the ventilator.It took me almost two years to learn how to crawl,stand,walk, and use my hands again but I made a full recovery. I can tell you from experience that being trapped inside your body and mind is more horrific than you could possibly wrap your mind around. I have horrible PTSD and 26 years later still have weekly nightmares about being completely paralyzed and unable to communicate again. But it made me appreciate the smallest of actions on a ridiculously high level. When the opiates had my balls and nose itching and I couldn't scratch them or tell anyone to scratch them for me and just had to lay there screaming in my head it made me realize how awesome it is just to be able to scratch something that itches whenever you feel like it. It truly is the little things, once you can't do them they'll be the first things you miss, and miss the most!

    • @rhondabonner9856
      @rhondabonner9856 4 ปีที่แล้ว +2

      Like when your hands are dirty you suddenly have to scratch your nose

    • @80brax04
      @80brax04 4 ปีที่แล้ว +1

      @@rhondabonner9856 exactly,but it's infinite, you can't scratch it or tell anyone to scratch it, just lay there stuck in your head. It was a very interesting experience to say the least.

  • @Crugroth
    @Crugroth 4 ปีที่แล้ว

    Your jokes were on funny and on point, I enjoy your style.

  • @TheOriginalJphyper
    @TheOriginalJphyper 4 ปีที่แล้ว

    I just read about this yesterday!

  • @SoniqStylz
    @SoniqStylz 4 ปีที่แล้ว

    Well this is comforting

  • @lovinmzre
    @lovinmzre 4 ปีที่แล้ว +12

    Omg you just kill me with some of your one liners... you hypochondriacs out there LOL

    • @carbon1255
      @carbon1255 4 ปีที่แล้ว

      Don't joke, it is a very serious and communicable disease of the brain.

  • @end-ai-media
    @end-ai-media 4 ปีที่แล้ว +7

    New zealand's just about in lockdown, and this was indeed a very educational and great historic look into how diseases take hold of our society. Please keep up with this great content :)

  • @jaz1551
    @jaz1551 4 ปีที่แล้ว +8

    "Just" a flesh wound! Hahaha 💖 Monty Python

  • @mechasentai
    @mechasentai 4 ปีที่แล้ว

    Facinating.

  • @LuinTathren
    @LuinTathren 4 ปีที่แล้ว

    The neuroscientist who worked on these patients in the 60s and then wrote a book about it was named Dr. Oliver Sacks. An absolutely beautiful writer. He wrote about patients with strange diseases and disorders, patients who had beed discarded or feared by normal society, and allowed us to see the world from their eyes. A different perspective of the world that was beautiful, strange, and funny. My favorite book of his is the short story collection called The Man Who Mistook His Wife for a Hat. The title story is about a man with prosopagnosia aka face blindness, an affliction Dr. Sacks himself suffered from. I also have it so it was especially poignant for me.

  • @xXJIJIPONGXx
    @xXJIJIPONGXx 4 ปีที่แล้ว

    I genuinely had this a couple of years ago. I had multiple bouts of tonsillitis within a very short period of time with antibiotics failing to get rid. After it had looked as though it was easing in my throat, I slowly developed extreme lethargy, and eventually had a couple of fits, hyperthermia, multiple symptoms of an encephalitis-like illness, and was hospitalised with multiple antibiotic and antiviral drips. After a few days, I started to stabilise, and eventually went home. It was suggested I had encephalitis lethargica, and had a violent immune reaction from a very stressed and active immune system. As a result of the infection, I've been diagnosed with fibromyalgia caused by the nerve damage and chronic fatigue! On the upside; not had tonsillitis since!

    • @rhondabonner9856
      @rhondabonner9856 4 ปีที่แล้ว

      They should have taken your tonsils out!! I guess that is not fashionable anymore

    • @xXJIJIPONGXx
      @xXJIJIPONGXx 4 ปีที่แล้ว

      @@rhondabonner9856 apparently due to an NHS wide cut back on minor surgeries, that wasn't an option unless I went private!

  • @echoberson
    @echoberson 4 ปีที่แล้ว +16

    Ouch @ "living paperweights." What a dehumanizing thing to say.

    • @rhov-anion
      @rhov-anion 4 ปีที่แล้ว +5

      You should see the videos where he talks about children as parasitic leeches. That's wry British humour for you.

    • @jhudom
      @jhudom 4 ปีที่แล้ว +2

      "parasitic leeches" is the most appropriate description imo

    • @emilyzachkitchen
      @emilyzachkitchen 4 ปีที่แล้ว +1

      It's terrible but it's true. There's other medical slang for these types of poor souls.

    • @Riwillion
      @Riwillion 4 ปีที่แล้ว

      Lemme call you a WAAAMbulance real quick.

  • @deanbuss1678
    @deanbuss1678 4 ปีที่แล้ว

    Crazy shit man!
    Oh , you know I'll share.

  • @blackblurable
    @blackblurable 4 ปีที่แล้ว

    Of all things I didn’t expect Simon to get hit by the stock market too. I knew there was to be a depression ahead of us after this. Hopefully there will be more talk about what else is going around. One of my first thoughts too, “What other afflictions are on the rise besides the current one?” The other bacteria’s, fungi, viruses and so on don’t take a holiday lol

  • @charlesmartin8454
    @charlesmartin8454 4 ปีที่แล้ว

    Glad you brought up the 1960s experiment with levodopa. Watching the movie concerned with that ("Awakenings"),......one could question the theory that a immune response to a hypothesized virulent coccus was so strong that it killed brain tissue. For these treated patients had memories and skills as before they had become catatonic........therefore the brain cells themselves were intact.
    Therefore the effects of the probable coccus infection must have caused the immune system to terribly alter neural transmission permanently Levadopa only temporarily helped with neural transmissions until the body (as with any drug) built up a tolerance.😔😔😔

  • @brandentempelmeyer4785
    @brandentempelmeyer4785 4 ปีที่แล้ว +1

    I have heard of Encephalitis but I've never heard it referred to by the other name that you mention.

    • @trelligan42
      @trelligan42 4 ปีที่แล้ว +1

      Encephalitis just means 'brain swelling'; the cause can be virus, bacteria, fungi/yeast or parasites. The symptoms vary quite widely, and can even overlap between different causes.
      So there are many kinds with many names. But it's easy to say just 'encephalitis' just as it's easy to say 'flu' for the many varieties of those out there.

  • @sandysani6045
    @sandysani6045 4 ปีที่แล้ว

    For a moment I was wondering if I was watching Business Blase, because of the way Simon was focused on the moustache of Dr. Von Economo! But I'm only in up to the 2:12" minutes mark and had to comment! Guess the relatively new relaxed atmosphere is just creeping in from Business Blase into Simon's other channels?

  • @skn180
    @skn180 4 ปีที่แล้ว +1

    I need the name of that awesome background music, PLEASE!

  • @TheNighthawke502
    @TheNighthawke502 4 ปีที่แล้ว

    Quite interesting, thank you Simon et al. Sounds like this would have made a good episode of House if it were still on. 😏

  • @markslater8861
    @markslater8861 4 ปีที่แล้ว +1

    Thank you. Very interesting. Speaking of virus and pandemics could you please do something on vaccines and antivaxers?

  • @lisascarrott6142
    @lisascarrott6142 3 หลายเดือนก่อน

    thank you for your content interesting i hope i never see this in my life time very scary

  • @snakey934Snakeybakey
    @snakey934Snakeybakey ปีที่แล้ว +1

    Oliver Sacks and Von Economo's research actually made me want to become a psychiatrist/neurologist. Unfortunately it didn't work out.

  • @ChrisSeaB
    @ChrisSeaB 4 ปีที่แล้ว

    How many different types of diseases can develop from STREP THROAT?? When I was a around nine, I developed Rheumatic fever. It affects the joints and can cause problems with your heart. Here's the kicker, I slept for least two weeks, only waking for briefest of moments. Usually when I was in unbearable pain. The doctors didn't know what was wrong with me at first. They thought it was just regular strep throat but after the 4th visit to the hospital and not showing any signs of improvement they finally figured it out.

  • @MoonFairy929
    @MoonFairy929 4 ปีที่แล้ว

    I’d heard of the disease, but had no idea it was so widespread.

  • @NOTSOSLIMJIM
    @NOTSOSLIMJIM 4 ปีที่แล้ว

    Shared

  • @danielsvideography1904
    @danielsvideography1904 4 ปีที่แล้ว +30

    I'm curious how their brain activity has changed as a result. If it is still very similar, in the ability to think about stuff, then does that mean our emerging science tech of reading brain waves could give people like this new life?

    • @WeirdOne19142
      @WeirdOne19142 4 ปีที่แล้ว +2

      Daniel Winfrey probably not yet, but soon. I feel like people don’t give enough consideration to the very real possibility that the children they sire today could be the last of the human species to die of natural causes. Medicine is advancing at an impressive rate. It’s really fantastic. Neuroscience is furthest behind, however, so not “yet.”

    • @belliotrungy9107
      @belliotrungy9107 4 ปีที่แล้ว +1

      Yes they trying all kinds of methods to test consciousness levels and communicate with some locked in patients ongoing now. Both invasive and non- invasive. Getting to the deeper parts of the brain effected in this is harder but definitely possible. You need to turn the computer on before you attach a monitor.

    • @WeirdOne19142
      @WeirdOne19142 4 ปีที่แล้ว +1

      Bellio Trungy yes. Neurolink is doing amazing work. I saw a documentary several years ago where a quadrapoligic had a device imbedded in his motor cortex. He was able to use it to interphase with a computer mouse. Sensational... absolutely breathtaking...
      Edit to note:
      neurolink is an Elon musk company. It was not responsible for the work I witnessed in the documentary. I only added it to show that many people are working on this.

    • @belliotrungy9107
      @belliotrungy9107 4 ปีที่แล้ว +1

      @@WeirdOne19142 besides neurolink there are non invasive techniques based on scanning and magnetic stimulation. Musk is a great engineer but the groundwork was already laid and other academic groups with less funding are making major progress as well.

    • @WeirdOne19142
      @WeirdOne19142 4 ปีที่แล้ว

      Bellio Trungy precisely

  • @tiedyedowl8367
    @tiedyedowl8367 4 ปีที่แล้ว

    I remember that movie. I had no idea it was based on real events. Robin Williams was in it, one of his few serious roles, really well done.

  • @Leifenguard
    @Leifenguard 4 ปีที่แล้ว +3

    Jokes on you I don't need the virus to make me lose the will to move or speak.