Convergent Mechanisms of Longevity | Prof Adam Antebi

In this webinar, Prof Adam Antebi, Director of the Max Planck Institute for the Biology of Ageing in Cologne, Germany, discusses his team's discovery on folate and methionine cycles downregulation in multiple longevity pathways and how this could be used for life extension.
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References:
- Closing video source: • 102-year-old runner ha...
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[@dalebullock810]

Yes do identify convergent pathways so we can whittle down on our supplement interventions!!!

[@yogesh4596]

Great 👏

[@msxisthesystem]

Great job! Hope the research could be done asap on humans

[@monnoo8221]

cannot be transferred to humans.

[@rhyothemisprinceps1617]

What I find really fascinating is relationship between one-carbon metabolism and metal homeostasis - especially iron homeostasis. I think that would be a great webinar topic. Another interesting topic would be Lipocalin 2 and neurodegenerative diseases.

[@kamanashisroy]

Watch out for methyltetrahydrofolate for b9 and methylcobalamin for b12.

[@kamanashisroy]

It seems exercise does not extend life. is it because it burns glycine to produce more gsh ? Can exercise and glycine supplement work synergisticly to increase lifespan ?

[@monnoo8221]

First, the point is that the first goal is extension of health span.
Second, most studies regarding exercise are not properly designed, and simply use the distinction 150 min of activity per week.
Third, the correct type of exercise has clearly been shown to improve mitochondrial health throughout the body. without imposing detrimental oxStress
Fourth, about your questions; no, no.