p53 Tumour Suppressor (2016) by Etsuko Uno wehi.tv

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ความคิดเห็น • 56

  • @tylercriss6435
    @tylercriss6435 3 ปีที่แล้ว +26

    These videos are just splendid. They solidified my fascination with molecular biology!

  • @gelatinocyte6270
    @gelatinocyte6270 3 ปีที่แล้ว +77

    I wish there were more animators like Drew Berry and Etsuko Uno.

    • @sabujsamaddar8489
      @sabujsamaddar8489 3 ปีที่แล้ว +1

      Yeh❤️

    • @soldadito34
      @soldadito34 8 หลายเดือนก่อน

      @gelatinocyte6270 keep watching crap like steven lgbtqia+ unvierse and never ecist good animators like these.

  • @andreabernardini7575
    @andreabernardini7575 3 ปีที่แล้ว +22

    Beautiful rendering! The flavour of transcriptional regulation neatly emerges from this video. Well done.

  • @Andy-rl8dq
    @Andy-rl8dq 3 ปีที่แล้ว +17

    I love this video and this channel, I learnt about p53 at uni two years ago and this animation brings it to life!!

  • @musicspinner
    @musicspinner 3 ปีที่แล้ว +2

    This is incredibly well done. Wow.

  • @floraye453
    @floraye453 3 ปีที่แล้ว +10

    I really like your animations. I think biomedical animations are very important for us to learn more about tiny things happening inside our cells. If you don't mind, I would like to ask your permission to share these videos to the other website in China for the embarrassing reason that TH-cam is blocked from accessing in China. Also because China now has rare beautiful animations about molecular biology. Of course, I will give sources of the original website. Thank you very much!

  • @MouAresounTaPneusta
    @MouAresounTaPneusta 3 ปีที่แล้ว +4

    I felt it when it said that enviromental stresses cause cells to either die, stop growing or repair themselves.
    I am between the latter two.

  • @songthanh896
    @songthanh896 ปีที่แล้ว

    Thanks so much! So informative!

  • @stevemotoq1411
    @stevemotoq1411 4 ปีที่แล้ว +1

    Nice production job well done ,,☑️

  • @xxeclepticxx
    @xxeclepticxx 3 ปีที่แล้ว

    Extremely impressive!

  • @ghadaabdelrazik2239
    @ghadaabdelrazik2239 2 ปีที่แล้ว

    Stunning!

  • @paulodias2172
    @paulodias2172 3 ปีที่แล้ว +1

    É POR ISSO QUE EU VOU SER UM BIOINFORMATA!!! SIMPLESMENTE PERFEITO

  •  2 ปีที่แล้ว +1

    Excellent biochemistry!

  • @rodrigomoreno11
    @rodrigomoreno11 3 ปีที่แล้ว +1

    amazing video!! is there a way we can have the full tetramerized Tp53 in PDB format to 3d print please?

  • @jaminhubner6342
    @jaminhubner6342 3 ปีที่แล้ว

    Seriously need to get some of those scenes into a free screen saver for computers and phones. Would boost your audience.

  • @glz1
    @glz1 3 ปีที่แล้ว

    Wow little machine going to work beautiful

  • @hpsauce1078
    @hpsauce1078 2 ปีที่แล้ว

    Mindblowing

  • @regulate.artificer_g23.mdctlsk
    @regulate.artificer_g23.mdctlsk 2 ปีที่แล้ว

    I'm not sure if I'm seeing this correctly, but it looks like the molecule models here include the hydrogen atoms. Usually these atoms aren't included, so it's nice that they're shown here - if that is the case.

  • @konanko169
    @konanko169 3 ปีที่แล้ว

    awesome !!!!

  • @pandeyistrying
    @pandeyistrying 3 ปีที่แล้ว

    This is great

  • @mayanksangam9205
    @mayanksangam9205 2 ปีที่แล้ว

    Amazing

  • @lucvandermeeren
    @lucvandermeeren 2 ปีที่แล้ว

    Amazing video showing the complex inner workings of the cell. I'd like to know how you make it.

  • @htowngurlL
    @htowngurlL 2 ปีที่แล้ว

    i could not watch because of the buzzing noise :(. i still liked

  • @SeanRhoadesChristopher
    @SeanRhoadesChristopher 3 ปีที่แล้ว +1

    This is amazing but not so easy to understand for the layperson.

  • @LuizRibeiroAcademico
    @LuizRibeiroAcademico ปีที่แล้ว

    Good animator, congrats

  • @spek2554
    @spek2554 3 ปีที่แล้ว +1

    What happens if you eat food containing cancer cells or tumor?

    • @avestator3763
      @avestator3763 3 ปีที่แล้ว +1

      Nothing, our stomach is filled with chlorine acid and a whole range of enzymes which disassemble every Protein and DNA in the cells into their very basic parts to be used again by the body. Even if they wouldn't or you would inject cancerous DNA into your blood system, Cells aren't made to take up any DNA lying around and using it for themselves, they can't. DNA outside of Nuclei or even cells is most likely viral and the Body destroys it and would never integrate it into their own system.

    • @regulate.artificer_g23.mdctlsk
      @regulate.artificer_g23.mdctlsk 2 ปีที่แล้ว +1

      If your food contains cancer cells, that means you're eating raw meat. Nothing will happen, of course, the cancer cell will just get digested.

  • @user-ed7gm7ol8k
    @user-ed7gm7ol8k 3 ปีที่แล้ว

    nice

  • @giantqueermess264
    @giantqueermess264 2 ปีที่แล้ว

    but what if the gene that dicided groth arest, death, or repair is the gene thats broken??

  • @d1dac0
    @d1dac0 6 หลายเดือนก่อน

    DNA must be unique to earth and we must be alone because there is no way something like this could evolve out of nothing in other part of the universe.

    • @user-xh9pu2wj6b
      @user-xh9pu2wj6b 3 หลายเดือนก่อน

      why not? And why do you think Earth is that special?

  • @alwynwatson6119
    @alwynwatson6119 4 ปีที่แล้ว +1

    So why is P53 turned off? Is it because the DNA that tells the cell to produce P53 is damaged by radiation or chance?

    • @danielkron2513
      @danielkron2513 4 ปีที่แล้ว +3

      Yes

    • @oluiolujk1025
      @oluiolujk1025 4 ปีที่แล้ว

      th-cam.com/video/8Mp7D7qWxG4/w-d-xo.html

    • @howtodoit4204
      @howtodoit4204 4 ปีที่แล้ว +1

      Daniel Kron yes what

    • @agata_cz
      @agata_cz 4 ปีที่แล้ว +7

      Because it is mutated to be switched off, and this can occur through damage caused by radiation or chance mutations. Every day, your cells mutate, some mutations are harmless, and few are deleterious/harmful, but radiation and UV light can increase frequency of mutations especially harmful ones. Humans have only 2 copies per genome per cell of p53 and it’s easy for us to loose one and have the other switches off. In contrast elephants have more copies of p53 and are less likely to acquire cancer. p53 is the most important rumour suppressor which causes cancerous cells to die, plays a role in a couple of pathways in the cell life cycle. Cancer is an uncontrolled cell growth, where cells grow out of the organs and in wrong places, and reproduce rapidly without control. You can find more on Google and in biology books, but hope this helps.

    • @alwynwatson6119
      @alwynwatson6119 4 ปีที่แล้ว

      @@agata_cz I was thinking if you had a correction enzyme that specializes in correcting p53 mutations as well as mutations in the DNA that contains the instructions for this enzyme then you would have a better resistance to cancer. Of course if there was some necessary reason for p53 to be turned off then that would explain why this has not evolved.

  • @coreymanago9684
    @coreymanago9684 ปีที่แล้ว

    And with that can you find a cure ?.

  • @MsShigeyuki
    @MsShigeyuki 3 ปีที่แล้ว

    I wish this video should be translated in french :(

    • @WEHImovies
      @WEHImovies  3 ปีที่แล้ว

      Ask Passe-Science Thomas Cabaret to do a French version
      th-cam.com/channels/sz9DiwPtgDvxJ-njWnieZw.html

    • @MsShigeyuki
      @MsShigeyuki 3 ปีที่แล้ว

      @@WEHImovies grand merci :) Thank you indeed have a nice day

  • @mmarquesrj40
    @mmarquesrj40 2 ปีที่แล้ว

    Poxa tnha que têm em português, rs

  • @KucingAhong
    @KucingAhong 2 ปีที่แล้ว

    Maha besar Allah atas ciptaannya yang sempurna

  • @mrmust2780
    @mrmust2780 2 ปีที่แล้ว

    The term WEHI means the message from Allah in Islam. Is your channel name related to the Wehi in islam?

    • @WEHImovies
      @WEHImovies  2 ปีที่แล้ว +2

      No, the name WEHI comes from our longer (former) title, the Walter and Eliza Hall Institute of Medical Research

    • @ichigo_nyanko
      @ichigo_nyanko 2 ปีที่แล้ว

      can you tell me the term in full? how do you pronounce and write it? when I typed 'WEHI' on google it doesn't appear.

    • @mrmust2780
      @mrmust2780 2 ปีที่แล้ว

      @@ichigo_nyanko Vahiy

  • @Zmax15
    @Zmax15 4 ปีที่แล้ว

    Lol whut?

  • @terozak4140
    @terozak4140 2 ปีที่แล้ว

    This is nothing but a program ...