Googles AI response. The drug AP is used to selectively destroy senescent cells in mice. Aubrey de Grey, co-founder of the SENS Research Foundation, has expressed excitement about the use of AP and other drugs to target senescent cells. Senescent cells are abnormal cells that are breaking down but resist dying. They can appear in the human body in a person's 60s, but can arise earlier in people who are obese or have a chronic disease. Some suggest that senescent cells may catalyze the aging process. Other drugs that target senescent cells include: Dasatinib: A leukemia drug that, when combined with quercetin, an extract from apple peel, can make elderly mice live 36% longer Metformin: A diabetes drug that can inhibit senescent cells' secretions Glucocorticoids: A group of steroid hormones that can reduce inflammation by down-regulating NF-κB transcriptional activity Rapamycin: An mTor inhibitor that can interfere with the IL-1α/NF-κB axis
Private businesses don't want to spend on this because of profit margins, but it seems like academia is just as interested in their profit margins. Is nobody just curious anymore? Does anybody study stuff if there is no profit?
Great interview with the man himself!
Excellent interview!
Super cool of in person instead of zoom.
Just testing out a few anagrams for the lelz:
1) Banker Zest, Anally
2) Brazen Alley Stank
3) Sleazy Barn Anklet
4) Zany Skeletal Bran
What was the drug he uses to kill sinecens cells?
Googles AI response.
The drug AP is used to selectively destroy senescent cells in mice. Aubrey de Grey, co-founder of the SENS Research Foundation, has expressed excitement about the use of AP and other drugs to target senescent cells.
Senescent cells are abnormal cells that are breaking down but resist dying. They can appear in the human body in a person's 60s, but can arise earlier in people who are obese or have a chronic disease. Some suggest that senescent cells may catalyze the aging process.
Other drugs that target senescent cells include:
Dasatinib: A leukemia drug that, when combined with quercetin, an extract from apple peel, can make elderly mice live 36% longer
Metformin: A diabetes drug that can inhibit senescent cells' secretions
Glucocorticoids: A group of steroid hormones that can reduce inflammation by down-regulating NF-κB transcriptional activity
Rapamycin: An mTor inhibitor that can interfere with the IL-1α/NF-κB axis
Now to think of it, I have heard Aubrey mention AP before once or twice. Im pretty sure thats the drug.
Private businesses don't want to spend on this because of profit margins, but it seems like academia is just as interested in their profit margins. Is nobody just curious anymore? Does anybody study stuff if there is no profit?
How would they fund their lifestyles with no profit ?
We're not stopping aging 😢
Hurry. I'm 53.