Which Antipsychotics Cause The Most Weight Gain?
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- เผยแพร่เมื่อ 14 ก.ค. 2024
- Antipsychotic medications are powerful drugs that are used to treat more than psychotic conditions like schizophrenia. Many of them are FDA-approved to treat bipolar disorder and depression. Even though they work very well and fast, they have some big side effects like weight gain and insulin resistance, some more than others. A new research study has given us some insight on which ones are better and worse.
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References
Shymko G, Grace T, Jolly N, et al. Weight gain and metabolic screening in young people with early psychosis on long acting injectable antipsychotic medication (aripiprazole vs paliperidone). Early Interv Psychiatry. 2021;15(4):787-793
Højlund M, Lund LC, Andersen K, Correll CU, Hallas J. Association of Low-Dose Quetiapine and Diabetes. JAMA Netw Open. 2021;4(5):e213209. doi:10.1001/jamanetworkopen.2021.3209
Holt RIG. Association Between Antipsychotic Medication Use and Diabetes. Curr Diab Rep. 2019 Sep 2;19(10):96. doi: 10.1007/s11892-019-1220-8. PMID: 31478094; PMCID: PMC6718373.
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Abilify definitely made me gain weight when I was on it.
Yes when the drug first came out the company said it was weight neutral. But I’ve had patients gain weight on it too.
@@DrTraceyMarks it's definitely not much. I fluctuate about 10 pounds on abilify. It's much more barrable than when I was prozac.
@@jespo9034 your lucky then because I gained 70 pounds on Abilify on a 15 milligram dose taking one a day. So it definitely varies from person to person.
@@lucakat9262 sameeee
What meds are for people who hear voices?
I'll take mood swings over weight gain. The fatter I get, the less inclined I am to exercise due to joint pain, which then leads to a downward spiral with meds just accelerating the problem.
Same 😢
Same. I started Latuda and hear mixed things.
Amen I will not continue taking meds that make me gain weight.
It’s truly an unbelievably unfair choice to have to make, either way you choose.
They Rexulti it’s done wonders for the dark depression I had for years , worked day 1. Still working. Only 2 pounds she mentioned. I’m trying to figure out if this med effects blood sugar and other like triglycerides etc.
Seroquel and Abilify destroyed my weight. I gained so much, now I take first generation antipsychotic and stopped gaining weight. I prefer twitches to having my spine suffer. Hope that one day there will be a med that will work well and won't make people gain weight.
im sorry to hear that😢 Im glad youre taking better medication now
@@sunnybee9453 Thank you. I also have double scoliosis, so it was terrible and painful.
What Med are you taking now without weight gain
@@adiosgamer3793 Fluanxol
50mg seroquel caused weight gained?
Abilify for my depression/anxiety made me gain 15 lb in a couple months. It was a huge stress to me, especially since I already have body image issues (including gender dysphoria). But I looked online, and all the official sources said it was weight neutral, so I felt like the weight gain was somehow my fault. Now I'm switching to lamotrigine years later and hoping it'll go back down.
My doctor put me on Abilify and I gained 70 pounds on a 15 milligram dose a day. I asked my doctor about this and all he said was that I needed to exercise more. Finally, I decided to research it and found out that, yes, it can cause weight gain. So I slowly weened myself off of it. After a month of not taking it I lost 16 pounds. I'm continuing to lose. Plus, I found out it can cause you to overspend money and gamble a lot. So I also noticed that not only was I not hungry as much but I quit going on horrible spending sprees. For some reason, I lost my desire to buy things all the time. I was wasting thousands of dollars a month buying things I didn't need. I had to file bankruptcy once and I was behind on my rent and I owed my mother money. So I wouldn't recommend Abilify at all. In my case I changed for the better. Another person online said they had gotten in so much gambling debt that they lost everything. But, when they stopped taking Abilify, they didn't feel the need to gamble anymore.
Personally I think these and other antidepressants need to be researched more. Please, look at the side effects of anything you are taking. Plus, it may also help to further research the drug for any further or worse symptoms it can cause. So definitely be careful.😳
I’m the only one losing on abilify? Olanzapine was a nightmare
@@lubnasalamrahman1556 consider it a blessing. It's hell if it doesn't work for you.
I gained 80 pounds on Abilify. It's NOT your fault.
I love lamotrigine. Been on it for about 6 years now.
Zyprexa was awful for me, almost 100 lbs of weight gain last time I was on it. But it literally saved my life, so I'm not angry about it.
No one can really understand this comment unless they’ve gone through it themselves. I’ve been there. It ruined my body forever and destroyed my health and I’d still do it again.
I say it often but I’d rather be chunky and alive than thin and probably in a casket by now. Schizoaffective doesn’t play around and despite gaining close to 80 pounds in four years, I can’t be mad. I can’t be mad that it’s possible for me to get out of bed and actually go to work without a mental breakdown. I can’t be mad that I can actually clean my house and take care of things and myself.
I am fat but I am fat and alive ✨
thank you so much dr marks!!! your videos have been so so helpful to me! i was diagnosed with bipolar 1 recently and it’s been confusing to navigate but your videos have helped me so much! i was put on seroquel and have been very worried about weight gain. this is a very helpful video
This is great information for my medical studies, thank you doctor!
Very good! Thank you!! You always give the best information!!❤️
Thanks Dr. Tracey for your informative videos.
Hi Dr. Tracey, thanks so much for sharing about mental disorders. I hope that people can find the strength to let go of their past and discover hope for a happier future💌💌.-Nicole
My sister is normally just a little dinky thing, but she was put on Abilify, and OMG she ballooned out in just a couple months. It also turned her into a vegetable.
My aunt was almost anorexic and it made her balloon, too...
Made me balloon in only two months aswell... its criminal..
Good video!
Thank you Dr. Marks! Will you please make a video on adhd drugs. How they work, best way to take them, how to increase effectiveness, drug holiday, etc…
This video was very helpful
Good morning Doc!
I've taken literally all 10 of the medications on this list, and 9 of them caused me to gain a significant amount of weight. (80-100 pounds!) The only one that did not affect my weight, and I was actually able to lose weight while on it, was Latuda. Unfortunately, I eventually developed a sensitivity to the akathisia caused by Latuda and had to stop taking it. Since then, I've regained all the weight I lost, plus 20 more pounds from trying other antipsychotics. After years of this, I am finally OFF antipsychotics for good (with my doctor's approval). I am currently morbidly obese and am seeing a bariatric doctor to help with weight loss. Hopefully I can get back to a healthy weight. I couldn't while on antipsychotics. It's kind of pointless to be on a medication that's supposed to help with depression, only to gain 100 pounds from it and become even more depressed because of your weight.
Thanks for sharing!!!
Yes thank you for sharing. I gained 80lbs in the past year, as a result of severe binge eating and lack of movement, which was triggered by immense workplace/life stress which had my bipolar 2 running amuck. I thought medication was the answer, but I am already 120lbs overweight- I don’t see how going on meds that cause weight gain will help me feel better cause any more weight gain will come with some more serious health problems.
I read somewhere there will be an injection which can help obese ppl lose 25% of their body weight. I think it will be out in 2024 or something.
Honestly these doctors have no clue. Use an ems belt they work!@@KimJilene
I’m so sorry, no one should have to choose between the multiple life-threatening physical conditions that gaining that much weight causes, and having no quality of life due to untreated psychosis.
I experienced the same thing to a lesser degree (“only” gained 50 lbs, only had to try 4 or 5 meds, and I was able to be off the meds in a year so most things weren’t permanent for me), and it really ruined my life, so I have a lot of empathy for what you are going through.
This is a great video. I would love to see a similar one in regards to SSRI’s.
I have been on Trintellix for several years at 20mg (the highest dose) and even though the FDA states it’s the only SSRI that does not cause weight gain, well, that is a myth. I was about 145 lbs. when I started and have creeped to currently 195 lbs. I have a small frame and am 5’ 9”.
I get so angry that most insurance companies (including Medicare) does not cover any weight loss drugs. I also suffer from hypertension and the weight I carry is not good at all.
My doctor attempted to get me on Wegovy but there really aren’t any insurance’s that cover it. The OOP was approx. $3,500 for one month (4 injections).
Even though Ozempic is the same exact drug, and only $10.35 co-pay per month, because I don’t have a diagnosis of diabetes I can’t get it. Phentermine is also out of the question because of my severe GAD anxiety.
There’s just ZERO solutions out there for people who struggle with drug-induced obesity.
🌴☀️🌴
Thank you Dr. Tracy for your informative mental health videos.
your hair always looks so good!! do you have a stylist or do you do it yourself?
My poor sister with severe bipolar has been taking a variety of antipsychotics, etc trying to find one that helps. She has gained an obscene amount of weight because of it. It is so hard for her.
I taken Zoloft/Seroquel and gained 15 lbs as a teen. I’ve taken Zoloft as an adult and gained 30 lbs with no end in sight. I don’t take either anymore and am so thankful Lamictal hasn’t caused weight gain.
Hi Dr. Marks, I am from Brazil and love your videos, could you talk more about rexulti to bipolar disorder? I am taking and has been very effective until now, I wish know better about it.
stopped my meds (due to budget insufficiency) and i felt better than the time i was taking them.
Lucky you. Not all of us are that lucky.
I would love to see a video about your takes on occult themes such as astrology and mysticism!
I’m on olanzapine for 22 years 10 milgrams is my maintenance dose, I also am on fluoxetine for 17 years now. Since I started those medications, I gained around 25 kilograms. I also developed eating disorder (bulimia) 15 years ago because of weight gain and it lasted for around 5 years (I don’t have bulimia anymore). So yea, it’s definitely not easy and consequences of these medications can be really harmful. I also have now high cholesterol, damaged liver, insulin resistance and pcos.
Control carbs and all will fall in place.
I’m also on olanzapine !! I well I also gained weight
@@rainiermoniz828 I am doing a low carb diet and I fast every day and still I didn’t lose much weight. And it’s still very hard because I have cravings for sweets and carbs because of olanzapine. I also try to exercise.
@@rainiermoniz828 and I actually gained around 36 kilograms but I managed to lose 11 kilograms due to calorie restriction in the last 6 years
@@rainiermoniz828 that is not true at all. Please do not spread misinformation!!
Abilify has made me gain weight but only a few lbs. At first I was upset about it because I noticed working out wasn't giving me the same results. But then I reminded myself of how helpful it's been so I'm doing much better mentally (towards the weight).
Happy to hear ur progress!
Risperidone was what ruined me as I gained 120lbs in 9 months. Then I switched to aripiprazole and gained another 20lbs in 6 months. I was then reassessed and prescribed lithium. So far, I've lost 77lbs, and I've not plateaud yet! Also, I'm much more stable than I had been on the other medications, and more awake and alert.
Doctor, please talk about treatment-resistant anxiety
Thanks for this video! But what about clozapine?
I'm 5'8 and used to sit around 190lbs to 200 lbs. My doctor gave me Risperidone and I gained about 80lbs in one year.
Bro my psychiatrist had me on risperidone for 6 months and I gained like 45 pounds
I gained 50lbs on risperidone in 6months
I've just been put on 25mg quetiapine (2months in) and already gaining substantial amounts of weight, dose being upped gradually to 100mg in next few weeks. Absolutely gutted by the weight gain, making me even more depressed and anxious, i cant afford to buy new clothes 😢
You should try keto and be mindful to fight the snacking
Quitiapine made me get high cholesterol. I had low cholesterol until I took it.
@@tyevequepr.tie-a-vec this is so insulting and is misinformation. Keto is extremely dangerous and putting someone who has increased cholesterol and triglycerides on a Keto diet is fatal. You should NOT comment on things you know nothing about.
Also, when I had a similar medication experience on antipsychotics, I would nearly pass out from low blood sugar symptoms if I didn’t eat constantly. You don’t have a choice.
@@fieldofreeds8581 You have issues and one of them is NOT reading. @lilycat5 is free to do what they want but, YOU will not accuse me of doing something because you won't read.
Hi @DrTraceyMarks, thanks for this video, which I find very relevant being on 300mg Quetiapine XR for almost a year and having gained a lot of weight...
My psychiatrist suggested switching to Lithium recently, so although it's not an antipsychotic like the meds in this video, do we know where it places in the weight gaining scale vs. say Quetiapine?
why is there rick and morty weight gain/force feeding fetish content in this video
Such bad choices/weird editing. Makes me very uncomfortable…
fr tho how did they find it without stumbling into other fetish content and understanding like "oh shit, that's nsfw"?
Thanks for this video. Is Clozapine still considered the biggest weight gainer of all the antipsychotics? Thank you 🙏
Seroquel made my best friend gain over 70 pounds in like 6 months.. .... when i quit taking benzos i lost 50 pounds.. i realized i wasnt hungry anymore as much either..
In that case you should curb your appetite and definitely do not eat after 6:00 p.m. and no snacking. You know that going into it must take steps to counter the tendency.
how much was your friend taking? did your friend's doctor not offer up an alternative? im taking 200mg and my doctor was monitoring my weight the first few months, he said we will find an alternative if it started affecting my metabolism
That's the devil in a bottle I remember taking Seroquel once that didn't help no skizoprhina for me my thoughts got louder and the world around me I couldn't hardly hear it ,if anyone even tried to force feed me that medication there's going to be a fight never again good luck to your friend
I gained 50lbs. It put me up to abt 170. It turned out I didn’t need it. Found out I’m autistic! 😮 Im back down to 130. Got most of it off😊
@@JSFGuy I never ate more on Seroquel. I gained 50lbs
I can’t get “Fat” by Weird Al out of my head now. Great video!
Oh yay, I am on vraylar 1.5mg for depression and am happy to see it is the 2nd lowest on the list for weight gain.
How has it been after 11 months? I'm supposed to start vraylar, but I lost 150 lb the healthy way! Whilel not being on any anti- psychotics at all. I'm so afraid that all my hard work is going to go right down the tube taking medication! Have you gained weight significantly over the last 11 months? Has it actually helped you? I would really love to know. I hope you're well.
I never had a weight problem until I was prescribed Abilify. I gained somewhere between 60-70 lbs in less than 6 mos. Needless to say once I finally drew the parallel I asked my doctor to change my medication even though at the time she insisted one had nothing to do with the other. That was 10 yrs ago and I’m still carrying that extra weight bc no matter what I do I can’t get that excess weight to budge.
Use an ems belt it really helps.
Not sure how on top of the autism research/news you are, esp with female adults being diagnosed, but I'd love to see a vid about ASD vs BPD, as it seems to be one of the most misdiagnosed.
Thank you so much for your work. I take Quetiapine before going to bed to sleep well. And I take minimal dose.
@Dr. Tracey Marks do you have any information on escitalopram and weight gain?
What's with the animation at 1:31?? The editor really didn't do a great job at hiding their prejudice with this video....
@@Laurap01 You didn't notice she was being force fed like a farm animal?
That is some weird fetish content. The character is from a tv show called Rick and morty. I think dr Tracy needs the editor to check their source content.
Yeah the weird clips of people gaining weight feel extremely offensive and bizarre… bad choices.
Hello Tracey!👋
Dr. Marks, this might not be something that you can help with, but I'll still ask. My endocrinologist recently found that the reason I black out after every time I eat anything, is because my proinsulin isn't at what Google says is safe (7-9) but 61.
I also don't take any psych meds. But what you've said today makes me wonder if there is a med that'll keep my pancreas from making this much insulin. Can you help? Obviously I'll talk to my PCP before anything else, but I'd like a lead.
I'm on mirtazapine for anxiety (in the UK) I put on around a stone in just a few weeks. I was eatting 3 wraps for lunch and bags of pop corn. I would have dinner, then at night, not long after I took my medication I would pig out on 3-4 bags of crisps. I've reduced my dose and find Im back to my normal eating plan. If it stops me having consent panic attack and helps me sleep then putting on a few stone, well I can live with that.
I’m on seroquel I must admit it does help with my insomnia but the weight gain!!!!
I took quetiapine. This caused noticeable bloating and weight gain, not too much, but enough to make me feel insecure, which affected my mental state and made my depression/hypomania worse, and because of this, my doctor increased the dose of quetiapine. And so on. Now without quetiapine I am trying to lose weight and it is quite difficult. I'm afraid that my body was ruined.
Why would you allow your doctor to INCREASE the dose for something that is already making you gain weight? Speak up. Say no and try a different alt. Closed mouths do not get fed. Idk how people just let their doc call all the shots. Its your body, not theirs.
@@grassfedcharlie and I don't know how people go to assumptions about others without knowing details. But here we are.
I was prescribed Mirtazapine by my local Hospital in February and have since felt really down about how much weight it’s putting in me. I spoke to the psychiatrist at my first review and begged him to change it to something less trouble, but he just doubled the dose on the spot.
So it is with great will power and suffering that I shall walk away from them… very very slowly. I’ll either die by my own hand or find a solution myself. I have been betrayed by those who promised to help on numerous occasions and I just wanted to tell my story before it’s too late.
usually gets better when you completely stop any business with a "specialists" and pills
The weight will come off eventually. I meet a girl in respite who was morbidly obese from this medication and promptly took myself off it. Sounds like you need a third opinion, plenty of alternatives out there unless you are anorexic, I dont see why they have done this to you.
Can you do a video on medicine that doesn't cause weight gain?
You might watch all of this one and see if she mentions that before asking.
@@JSFGuy obviously she did because every medication the doc listed causes weight gain (some more than others but it’s still weight GAIN)
Gained 50 pounds on Risperdal, then lost all the weight in a year after stopping it - doing nothing differently in terms of diet or exercise. Gained 20 pounds on Zyprexa. Note: I was on the smallest dose of each.
I also gained 50 on risperidone after about 4 months and then shed all of the weight immediately when I stopped taking it…no changes to lifestyle,diet,exercise, etc.
Interesting.
Im on 400 mg Seroquel for DID and C-PTSD. I've for sure gained weight, and I'm trying to diet. It's not working well. But it's so worth it, it works so well. Literally changed and saved my life. So I have no choice but to stay on it, even if it makes me hate my body.
Ugh. This is the dilemma I am in now. I have terrible body image issues but olanzipine has been working so well. I’m stuck. I don’t want to end up bulemic.
@@grassfedcharlie I feel you so much, same here. Praying we'll find a solution soon lmao
My son is now on 400mg Seraquel. He has extreme laughter. Would anyone know if that is effects of medicine or psychosis? Thanks
@@Fred-Faizi I don't have psychosis, but im on 400mg of seroquel too with no symptoms like that. So it might be psychosis.
@@user-wv5ue7ny6u hi, Seraquel is anti-psychotic meds. Not sure what DID is. Thanks for your response.
Around two years ago I arrived to my current med cocktail. All of them are weight gain-inducing, and I gained around 30lbs as a result, but since I was incredibly underweight I'm finally at a normal weight for my height and age. It seems to have plateaued as well! I guess I'm very lucky in that respect.
do you mind if i ask what medications you're taking?
@@oopsmybad4607 Hello, sure! I'm taking lamotrigine 100mg, mirtazapine 30mg, and quetiapine 200mg. All at bedtime. :)
Should make a video on Fundamental attribution error
I want a video on ADHD medication and weight gain please!
Can you talk about weight gain and efficacy in anti depressants?
Did you mean "lowest effective dose" instead of "least effective dose"? 7:39 (since "least" describes "effective" while "lowest" describes "dose")
I've struggled with my weight ever since puberty, before my mental illness symptoms presented and way before I ever got on medication. I don't know if my weight gain since 2016 has been from medication, but I'm trying to stabilize my weight into something manageable (and not *painful*). It's going to take me time to figure out if my calorie counting is effective, at least a few months, but hopefully I'll have enough data by my next doctor's appointment that we can assess if the antipsychotics are affecting my weight.
I'm over olanzapine( because of bipolar disorder), my weight is fix, its not increasing, I'm happy 😂
Look, I'm at home laughing and giggling reflecting on memories. My olanzapine was added to my SSRI. I wish I only gained 8 lbs in six weeks. I gained 20 lbs in the first month and peaked at 50 lbs when my new doctor wouldn't prescribe it anymore. It was an adjustment being heavier but it was the best I felt in years. I've lost some of the weight but not because of the med change, but because I inherited thyroid issues and hyperthyroidism had me burning off eve👏🏾ry👏🏾thing
You literally developed thyroid issues. Why are you clapping
Would be interested to know how the older typical medicines compare to the newer ones when it comes to weight gain.
I gained 44 pounds in three years with amisulpride. I tried to walk and work out but still it had no effect. It triggered my prolactine to get 6 times higher than the norm. Took about 1 year to finally get the hormone back to norm. 👌🏻 While using I didn’t mind the weight gain ‘cause I didn’t give a duck but being off it triggered my body dismorphia.
i mentioned to my psych that ive gained nearly 70 lbs over the past 2 years (when i was previously consistently one weight). she said "maybe its your testosterone?" when ive only been on that for a few months
Ansofaxine (The new Antidepressant)
When will it be released , Doc ?? (Hoping to get a video about it)
My son has tried Zyprexa, Lovux, Abilify, flouxitine and now Seraquel. He still appears to be in a state of psychosis but no doctor knows why. For the past month, he has been having frequent laughter throughout the day. Has anyone else experienced this laughter before? Thanks
Abilify made me gain 110 lbs in a year and a half.
OMG 😱
Omg I'm getting off Seroquel to get on abilify Seroquel causes weight gain I didn't like
@@angelorange9334 I'm just starting zyprexa. They say it's bad.
i was on risperdal for a long while but a small dose so nothing major happened but when they increased my dose i literally gained over 50 lbs in a very short time (like a few months)
I gained 38 lbs from risperidone in 4 months. Now I am on ziprasidone and struggling to get the weight off.
Godspeed friend. My boy was put on risperidone and ballooned like nobody's business.
I was so angry when a child psychiatrist stupidly said that he could be overweight and behaved, or skinny and out of control. All I was asking for was weight management. I almost made her cry.
I hope you aren't mistreated by doctors and are managing well. 😎✌🏾
Ziprasidone was life changing for me. It started working very quickly and didn't change my weight at all. Good luck!
@@Gumbier_Than That sounds awful, I hope you found a solution! My psychiatrist is great but we are only managing my illness so-so, unfortunately.
@@miss.ringrose Thank you, and good luck to you, too! So far, the psychotic symptoms seem to be in check.
@@miss.ringrose8:27 I had identical experience to yours. Was a miracle drug that worked immediately and only one that caused no weight gain.
Can you list entire list of more medications and weight gain correlation? Specifically paxil.
I'm on Latuda. I lost weight in the first six months. I'm going up in my dose because of my depression so I will just wait and see what happens. My blood pressure has gone up from around 120/60 to 140/80 and I gained five lbs back. I'm a little concerned but I will just watch what is happening and if anything else changes I will contact my med doc right away. They already know about the blood pressure but I forgot to bring up the slight weight gain.
I don’t understand, you said you lost weight on Latuda, but gained 5 pounds back? How?
My daughter took Abilify and she gained more than 2 pounds in a week . In 5 weeks she was more than 10 pundits heavier. 😢😢
My psychiatrist tried multiple different antipsychotic medications to try and manage my unipolar psychotic depression when I was 18… the only one I could (kind of) tolerate was risperidone. I started on 1/2 of the starting dose because my body is extra sensitive to most medications. On this dose over about 4 months I gained 50 pounds, had elevated triglycerides, and was pre diabetic (no family history or risk factors). I weigh roughly 100 lbs usually, so that was an insane and life changing weight gain for me. It endangered my life. At the fastest period of weight gain I could not even roll into fetal position because my skin was so taut… it hadn’t had time to stretch…. and once it did I got stretch marks from hell.
On risperidone I also had increased prolactin levels, so I was producing breast milk, and it would leak constantly through my clothes.
I felt like I had extreme low blood sugar (faint, light headed, dizzy) if I didn’t eat every 3 hours.
To be honest, even with all of that said, it was better to be on the medication than not, because psychosis was the scariest thing I’ve ever experienced. I did not have any quality of life at all with my psychosis. I was able to get off of risperidone after about a year of managing my psychosis, and I have learned how to manage it with my other meds and monitoring my anxiety… but it no doubt changed my body forever.
My weight gain never plateaued, I kept gaining until I was off of it. When I stopped taking it, my body shed the weight immediately (although of course my skin was still stretched out).
I hope that we can continue to develop more options for people experiencing psychosis so that they don’t have to make the choice that I did. The hell that my body went through on risperidone was actually the better option because I actually had a life.
The scariest thing I can think of is having the psychosis return and having to go back on the risperidone…
What in the Hell is "Psychotic Depression"?
Wow didn't realise the side effect from rispiridone could be so serious
When my Rexulti Rx was increased, I lost 50lbs in 2 years. I wasn’t hungry / didn’t have a compulsion to eat and I was nauseous so I just didn’t eat.
Both of the medications I take are on this list. I take olanzapine and risperidone
Quetiapine and stereoids for asthma. I stop on 90kg but I was all life 60kg.
It is changing my view
I gained 80 pounds on quetiapine. And man is it depressing. I'd been slim my whole life up to this point. My weight stabalized after switching to rispiradone. But I still couldn't make much progress getting it off. I was finally switched to lurasidone. Which has also been more effective at managing my bipolar symptoms with the least sedation. But I'm still struggling to lose this weight. And because of the weight gain and how bad it makes me feel physically, I've started skipping doses of my medication. I know that it can get bad. Bipolar 1 is no joke. But I can't live like this. It hurts to be this heavy. I have a small bone structure. I'm not meant to have so much weight on my body. My back hurts every time I walk for more than 5 minutes now. And that makes exercise so much harder. I'd always been fairly fit. Usually doing about an hour of exercize 4 to 5 times a week. And now it's so hard to get the exercise in that I want to. I feel lucky if I can push for 3 hours a week. And the exercise helps so much with the deoression.
I've been carefully monorting my sleep and mood daily though. And trying to be real mindful of my symptoms. I've been trying to be mindful of when I start to feel more paranoid. (A common symptom when I'm starting to become manic) And I've taken my meds when I do see the symptoms coming on or if I start to sleep less than I should. And I'm focusing on keeping a normal social rythem. I have alarms set for everything I need to do, including my go to bed alarm. And honestly, I think that close monotoring and medicating only when symptomatic could really be a good option for treatment. But I do plan to be on my meds all the time when I'm done getting most of this weight off.
I'm just so afraid of ending up diabetic or with heart disease. I'm in my 30's now. And that's the age when struff starts to catch up with you. I have a family history of diabetes and high blood pressure. And I feel like obesity could also make glaucoma worse. And I'm predisposed to that as well. We gotta start treating the whole person while managing psychiatric illness. I wasn't even warned of the weight gain side effects. How can I combat something when I don't know it is going to be a battle?
I do feel like lurasidone should become one of the first line medications now that there is a generic out of it.
I just want to feel healthy, mind and body.
Bipolar I is horrible. I have many skills to keep myself relatively sane and it still hovers over me. Use of alarms is vital to maintaining a life. I deal with most of your physical challenges as well. I feel for you. I hope things improve. I want to feel healthy mind and body.😎😎
I really feel for you. I am also a small person and had been slim (even underweight naturally) my entire life and I gained another half of my body weight on risperidone. I can relate to the back hurting/bones hurting feeling. I felt like my frame couldn’t take the extra weight! And I did become pre diabetic from the meds (no risk factors) and my triglycerides were very high. The drs had to pull me off the meds at that point for the sake of my physical health.
There is no easy path through this. No one understands accepting such damaging side effects unless they’ve been here. It’s not a real choice.
I hope you can find a solution, and that medicine comes up with more solutions for your disorders soon!
@@tjw9985 yeah. I still deal with symptoms while fully medicated. They're just more manageable. It's just exhausting to deal with for so long. And it never goes away. I've learned a lot of good coping skills with therapy. And I'm rather stubborn. So I'm gonna keep on keeping on. I just want there to be more available for us to get to and stay in good health. I think we deserve as much normality as anybody else.
@@fieldofreeds8581 Thank you for your kind words. A lot of people don't seem to get how painful all the extra weight can be for those of us not built to be thicker. I literally have a tinier frame than a lot of people who tend to be heavier. While it's important for us to have our sanity, we still need to care for our bodies. And the current med loadout and way our psychiatric care is often handled doesn't factor in the whole person. I miss the feeling of being physically healthy. And I feel like I've been floundering trying to figure out this weight. And any time I go off meds I tend to drop a few pounds. So it doesn't make medication very palatable. If it were 5 to 10 pounds, I'd just deal with it. But last time I weighed myself, I was up past 150% of my original starting weight. And I hear this same story over and over again. We deserve better.
Same story with Quetiapine.. I've also always been rather slim/fit or just normal for a guy. I now gained enough weight that i sometimes feel like im pregnant 😅 or like i have a beer belly when i literally never touch alcohol...
It also gave me stretch marks on my belly and thighs which made me even more depressed about it, like i now ruined my body irreversibly and the marks will always be there to remind me.. i know there are worse things but with depression it's hard to brush these things off.. but i do tell myself it's no big deal, and that there's nothing to fix it anyway, and it's not like I'd have surgery for that if it even exists..
I just feel like i tried so hard, finally took the steps to seek medical help, and just got disappointed in the end.. i know it's a journey that can be long, but sometimes it's just too much and life/deadlines etc dont always allow to just spend months or years trying to find the right thing, trying meds that can sedate you so hard you have to stop work/go on sick leave and can't even wake up, end up needing 12h+ of sleep, gain massive weight, AND its ineffective for both my sleep issues and depression in the end... it was initially helpful sometimes but not anymore.. just ugh.
Now my pdoc suggested switching to lithium.. i guess i have to try although im just over it and scared of side effects a this point tbh.. also very scared of agonizing Quetiapine withdrawal that i had the misfortune to experience after i was told by my doctor to reduce from 400mg to 300mg in 1 day..
Its just all too much sometimes, and it feels like it just added shit on top of the depression.
And as a masters student i've had to go on sick leave from my work-study program which just sucks.. especially as a foreign student i might just end up failing and getting sent back.. idk
Sorry ended up rambling 😅 eh what can you do though.. i just have to keep trying and hope to recover just enough to bounce back...
it must be a mixture of metabolism "slow down" side effect...as well as maybe a reduction in physical activity due to low mood lethargy,
adding betahistine can decrease this side effect because its an H1 agonists, but its not available in the US
I have always been underweight but suddenly gained weight and sticked to a certain weight range ever since I took olanzapine. Far from being overweight but still...
I was on Sertraline for over a year and was taking 25mg. My appetite was totally increased and I wanted carbs! I had been eating low card and high protein for years before going on the meds, so the appetite change was strange. I gained 50lbs and am finally off the meds... I’m so tired of the insatiable appetite and weight gain😢 I’ve been off the meds for a little over a mo th and a half and my appetite is slowly returning to normal and I’m finally feeling full again.
Same for me, sertraline and every antipyschotic and antidspressant made it very difficult for me to control my appetite. I gained 100 lbs. I'm now on my journey of losing that weight and coming off of meds forever. 😂
One topic which could be Interesting is what cause antipsicotics to people who doesn't need them. Negligence exist.
I don't Know if already exist a video about that topic 😅.
My worst nightmare is telling my doctor I'm doing better and them taking me off or lowering my dose. Yes they are doctors, I get it. They aren't in my shoes though. Finally getting to a good place and then having the stress of possibly being taken off the medication is super counterproductive to me personally. One size will never fit all with mental health. It's not like the medication is doing all the heavy lifting. Im still in my body experiencing the excruciating pain that is living with MDD and working with the medication to have a morsel of what a regular life could look like, BUT with the notion in the back of my head that my doctor can decide that the protocol is that " you arent supposed to be on it forever." When its keeping you alive, only to offer mediocre group therapy services that make the situation worse.
At the beginning of the year I started taking naltrexone to control my alcohol use. I have lost 20 pounds since from A. Not drinking alcohol. B. The combination of naltrexone and Biupropion is a weight-loss medication that is out on the market under a different name. Contrave.
Advocating for yourself when it comes to mental health can be a struggle when you're side eyed for doing your own research. The google doctor gets a bad reputation but there are things like naltrexone that I found through doing my own research that my docotor would have never been on her radar. If you know too much people think you're faking it. If you know too little you're screwed with the wrong medication for years on end. Advocate for yourself.
I find either way is a worry because the other side of that is the doctor wanting to change dosage or the medicine itself because the doctor thinks you should be doing much better on the med and that has been a reality I've had to fight over in the past to keep them from "adjusting" what has proven works best for me.
@@mythias I know exactly what you mean.
Mini: I recommend that you avoid doctors and just treat yourself since you are doing so well. Avoid medications, since you probably know how tolerance and polypharmacy work with all your research. And if you develop issues, I am sure you can figure out what to do about the drug interactions and effects on your brain. You DO know more than they do!!
@@Cathy-xi8cb You should not tell people not to take their medicine. It could be dangerous.
My primary RX’d me generic Seroquel for insomnia. It’s the first med that’s helped. I was already 15 lbs above my preferred weight. I’ve been really careful about my diet and exercise, but the scale’s not budging, where I was always able to lose extra weight in the past.
I’m giving myself another month before I contact my primary and find another alternative. If necessary I’ll go back to OTC sleep medication, and herbal supplements.
Thank you, Dr! 😊
Olanzapine and quetiapine made me gain a lot of weight. That’s why my doctor prescribed mood stabilizers instead.
I gained 90 pounds in 6 months on mirtazapine without any diet change. Even though I stopped taking it immediately after those 6 months, now it's 7 years later and I'm still trying to lose even a fraction of it (diet, exercise, endoctrynologist - nothing works). It's horrifying
I discovered that you really change your diet, you eat more but you don't really notice until it's too late and even when you notice it you can't change anything.
That medication came straight from hell ! It should be forbidden; I turned into a monster in less than 2 months, it changed me forever
I think the video you used at 1:35 is like fetish content or something. Because the character is from the sci-fi show Rick and morty which is probably why there’s a mechanical machine making her larger. Just letting you know if you didn’t.
Yeah the weird video clips added in it made me really uncomfortable
Maam can SSRI make you gain weight. I have been taking Escitalopram (cipralex) for 10 months and did gain significant amount. (Yes i also do think it can be because of my diet)
Regular AD like Zoloft made me fat AF and helped in no way. I got off them and jumped on Anabolic Steroids. I can't believe that anabolics get a bad rep compared to SSRIs
What! What about Geodon?
How come you're missing some?
And what Haldol? Prescribed by psychotic/sadistic psychiatrists?
Any information for us on the best antidepressants for elderly people? I think I need something, but I also worry about side effects, including weight gain. I am 70. I have dealt with depression and anxiety my whole life but stopped taking meds a couple of years ago because of my age.
I personally never gained weight on Prozac, but I was on a lower dose 🤷 the biggest side effects for me were dry mouth and sexual dysfunction (the former was the reason I came off Prozac, lack of sex was making me more depressed haha)
@@sianmilne4879 Prozac is a great medication. It's the only one I've been happy with.
JLK: you are at a greater risk of many things, including falls, if your dose goes up. Please try to find a therapist that does some of the cutting edge treatments for depression including CBT and DBT, as well as EMDR for trauma. You cannot risk ending up in a nursing home.
@@Cathy-xi8cb Yes, I agree. Have been trying to find a therapist. I’ve gone to therapists on and off my entire life. Never had any of them really help. But I would like to try to find a good one. Very hard to find someone effective.
Prozac made me lose so much weight that people thought I was anorexic.
I take olanzapine and it definitely caused weight gain 😫😫
ncbi ref for a bunch of ssris 2017 australia research is about 3% weight gain per year on average
I was on 500 mg quetitapine from 2020-2024 and I gained A LOT of weight. I went from 120 to 149 but I am a 4'10 female, so picture it.... I started to lose the weight by walking and eating healthier but it didn't really fall away until I got off of it and started Latuda.. if I had known the weight gain was due to that medication I would have stopped a lot sooner I was miserable.
I gained a ton of weight taking Invega but I’m wondering if I can lose weight while taking it, can diet and exercise help or is it pointless?
I gained over 60 pounds on Latuda.
I gained 24 lbs in 6 months on Vraylar
I‘ve been on risperidone and gained 2O kg. It wasn‘t only due to the medication, but it definitely played a role. Aripiprazole didn‘t have any negative effect on me, but it also didn‘t affect my symptoms. I‘ve taken quetiapine in a dosage up to 45O mg and it didn‘t affect my weight at all. I‘m now taking Haloperidol (and 1OO mg Quetiapine for sleeping) and I love it! I don‘t have any side effects. It just works. I don‘t have a schizophrenia spectrum disorder or bipolar disorder, I have C-PTSD and depression.
Do you know if there are any similar studies done on anticonvulsant medication? I am on Depakine (also known as Depakote) for my bipolar type 1 in combination with lithium and I've been gaining weight.
Yes, they are a risk for weight gain as well. But if you seize severely and damage your brain, you won't know it since you will be brain damaged. So it kinda works out.
@@Cathy-xi8cb I've never had a seizure in my life. As I said I take the med because of bipolar type 1.
Hi Dr. Tracey, my question is: Are there meds that help the brain get oxygen?
Bipolar 1 here. I gained considerable weight while taking olanzapine (~40 lbs.) and lost it almost as quickly as I gained it once I stopped that medication. I was first prescribed olanzapine during a lovely stay in a psych ward while I was experiencing acute mania, and two subsequent psychiatrists kept that prescription active for no other reason than that it had already been prescribed to me (even though my mania had subsided -- now I know this was a mistake). Months later I pointed out how it seemed to have a noticeably negative effect on my metabolism. After quitting the olanzapine I did feel slightly increased symptoms of anxiety, but the tradeoff was worth it overall.
I put on 126 pound on quitepine!!
I have a new consultants he put me on Aripazole,the weight gain,scares me so much I refuse to take it
Not from a vain point of view from a health point of view
Everything has a knock on effect…..I had a hospital appointment they took my BP it was so high they refused to let me home.
I now have stage 3 CKD which was caused by having high blood pressure for so long!
Abilify and Rexulti kicked my ass after loosing my dad young and then having post partum a year later it was added to my Zoloft gained 40 lbs in about a year and tried for 2 years spinning for 1 hour 6 days a week and eating healthy and my weight WOULD NOT BUDGE. Finally put it together and the weight melted off literally within a couple months. Blew my mind and was also irked that I was never warned about it or educated about the possibility that I would literally be completely unable to loose a single lb. while on it. It also does something to the H1 (I believe) inhibitors (metabolic) in the brain which makes the body hold onto the weight. Just educate us.
I've been taking Olanzapine 2,5 mg for a year now and haven't had the problem of weight gain... I gained 3-4 kg but as I was too thin it didn't matter