The Key Biomarkers to Measure With a Blood Test | Dr. Casey Means & Dr. Andrew Huberman
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- เผยแพร่เมื่อ 16 ก.ย. 2024
- Dr. Casey Means and Dr. Andrew Huberman discuss the key biomarkers to measure with a blood test.
Dr. Casey Means is a physician trained at Stanford University School of Medicine, an expert on metabolic health and the author of the book, Good Energy. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast.
Watch the full episode: • Dr. Casey Means: Trans...
Show notes: www.hubermanla...
#HubermanLab #Health #Biomarkers
Disclaimer & Disclosures: www.hubermanla...
This clip is from the Huberman Lab episode "Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation". The full episode can be found on TH-cam here: th-cam.com/video/8qaBpM73NSk/w-d-xo.html
How do you spell all those tests she mentioned?
1)Hemoglobin A1C
2)Triglycerides
3)Vitamin D
4)Homocysteine
5) TSH
6) Free T-3
7) Ferritin
Outside a CBC/Differentials
Comprehensive Metabolic panel
The above seven markers provide a picture of Metabolic, Immune, and Inflammation
Thank you!!!!
Inflammation marker is C-reaction protein
That's correct, however if I was only able to use 7 biomarkers, Ferritin not only predict inflammation, but also shows Iron storage in the liver which gives me a picture of Iron status.
Thank you 🙏
@@520cuban Thank you so much! 💕
Thank you, Dr. Means for the explanation, and Dr Huberman for having her elaborate on the biomarkers to understand them better.
Hubes is so good at acknowledging the flaws of a subject it's actually inspiring
11 mins is WAY better than the 2.5 hour vids.
She is a role model to future doctors
Kinda disagree with using waist circumference! Two men (one is 6'3", the other is 5'6") both having 38" waistlines propels you to a whole different universe! Might be better to use a height to waist ratio?
Yes. Much better.
I know right?! I keep saying this!
The best marker is to use a waist to hip ratio. Far more reliable than others.
Brilliant...just need to listen over and over...She got on track around 8 minutes...good stuff
I think so too , sounds clearer from 8 min
The Fasting Insulin levels are critical information. I am surprised that she missed it!
Ditto. And an hs-CRP.
The key biomarkers to measure with a blood test are:
- Fasting glucose
- Fasting triglycerides
- HDL cholesterol
- Hemoglobin A1C
- Total cholesterol
- Waist circumference
- Blood pressure
One I always ask for is C-Reactive Protein (CRP) to measure for inflammation
Cannot belive they did not include fasting insulin. Why try to guess if IR is an issue from the rmarkes -- measure it. I pay < $20 for that test and I wish I had know about it years ago before my FG and TG started to creep up.
True. I'm hoping that she covered it in the full episode. I think that the ones she covered in this "clip" were the ones that the docs wouldn't complain about ordering. They usually balk at running a fasting insulin test. To me it is SO important to know and can tell you SO much.
Yes. Getting the labs is needed. And, it is essential the patient digest the information.
Pun intended?
The key biomarkers for metabolic health and identifying metabolic syndrome that can be procured in an annual physical:
1. Fasting glucose
2. Fasting triglycerides
3. HDL Cholesterol
4. Total Cholesterol
5. HgbA1C
6. Waist circumference
7. Blood pressure
If the following things are in these ranges, and you’re not on medication for blood sugar or blood pressure, you are considered optimally metabolically healthy.
1. Fasting glucose
50 (women)
4. Total cholesterol / HDL ratio
< 3.5 / 1
5. HgbA1C
< 5.7%
6. Waste circumference
< 35 in (women), < 40 in (men)
7. Blood pressure
< 120 / 80
Dr. Casey says these are easy to change in 1-2 months with lifestyle habits.
If fasting triglycerides >150, probably b/c of excess carbohydrate intake.
If fasting glucose >100, probably b/c of excess carbohydrate intake.
If HgbA1C >5.7%, probably b/c of excess carbohydrate intake on average over the last 90-100 days.
If blood pressure > 120 / 80, probably caused by not enough nitric oxide activity caused by insulin resistance caused by excess carbohydrate intake.
@@kaihubbard4450thank you!
Thank you so much for the summary you saved me the time of having to watch it again to write it down. I pass on all except the waist circumference. @@kaihubbard4450
At 1:30, huberman admits his audience wants a little more time for explanation and not just a list of biomarkers.
Early on, he gave you a heads up that this clip would not just be a list.
Hi, what happens to the sugars, carbs, /triglycerides when you take statins ? How exactly do statins reduce cholesterol values even when you consume carbs /sugar? 🤨
She left out fasting insulin, the first marker to go up in insulin resistance. Total cholesterol is meaningless. Think about it: TC goes up as HDL goes up.
Right - fasting glucose is not all that helpful - insulin is much better.
She didn’t say total cholesterol. She said the ratio of total over HDL
Although, the triglyceride:HDL ratio is a good proxy for insulin resistance.
@@dirtyharry2534 Interesting - I hadn’t heard of that. Where can I find out more about that? thx
@@zenrand688 Dr. Paul Mason is one that covers this subject well. Try his presentation, "Blood tests on a ketogenic diet" (Low Carb Down Under channel). Dr. Ford Brewer discusses this ratio. Dr. Ekberg has a couple of good videos where he analyzes a patient's cholesterol results in detail. I've encountered others, but these ought to be a decent start.
Did she just hint at the Randle Cycle without calling it out by name? Why I think she did!
Optimal range - 3.15
Fasting glucose - Less than 100
Triglyceride - Less than 150
HDL > 40 for men, > 50 for women
Hemoglobin A1C - less than 5.7%
Total cholesterol to HDL ratio - less than 3.5 - 1
Waist size ratio less than 35 Inches for women, 40 Inches for men
Blood pressure less than 120/80
Interesting that we know ourselves from "Response / Reaction", like what's being circulated within. Ofcourse, it's the best available now, especially the fasting numbers. However, like the Schrodinger cat, the measurement could influence - means, we are measuring only what we want to know & not necessarily the full picture within. Ie, if I am paying my loan instalments properly, then I am good (I might be stealing or looting to pay). It need not tell me my capacity to face a challenge. Example: how good am I in actual "combat / stress / challenge". Like a Treadmill test, the numbers must show me my capability in combat, than when I am rested. That's a better indicator of "Health", especially "Active health". Current numbers are "Disease" finding than an actual Health statement. It's like seeing a picture of river, where as it's dynamic in reality. Health & numbers must thus be linked to other factors (futuristic) like social (mental) expression, familial conditions etc etc. An individual is actually a Group, networked reality. We need to account for the "Randomness". History based is seldom the future. We need to know Destiny than Fate, while dealing with Health & recommendation must be futuristic than history solving. Probabilities based of multiple factors are to be included as part of score & assessment. Example: ability to balance, ability to get up without support, from a floor sitting posture, HRV scores, etc etc. AI used measures are future than these crude numbers, as far as Health is concerned (not Disease). It's like "Credit score". Even things like O2 saturation at work, lung function numbers etc shows how we are at work (challenge) than at rest.
Good to send out to friends and family
She says these tests are very inexpensive if run outside the doctors office. And where might that be. If I look at questions or Labcorp it’s very expensive.
You interrupted her and she never got to the other tests.
Casey's awesome!!!
Yeah this is complex all of my markers are well within range but my CAC score is 3000! Trying to figure this out.
Go 0 carb immediately.
Yes. What Andrew said. Also, you won't get a full picture unless you know what you're Fasting Insulin is. Even then, a couple of others could be helpful to know.
But yeah, carnivore for sure.
He : Why do you talk like that
She : it's my voice
He : No it's not, it's a affectation😂😂
Can somebody write the biomarkers in the comments and their optimal levels?
Yes *you* can
Go 0 carb, exercise, get outside in the sun and lower stress through sleep then you don’t have to worry about the tests.
@@andrewrivera4029 Please don't go zero carb. Personal trainer/dietician/nurse. Processed carbs, sure. If you can, that's wonderful. But don't eliminate fruits and vegetables
Plus, you can do everything perfectly, and still have issues. This is a very ignorant comment
I understand it’s a short version of a longer conversation but we got sidetracked by triglycerides and fasting glucose for the eternity. While no time was used to clear up the ApoB nor LDL
I can’t believe you didn’t mention fasting insulin! Wow! Hyperinsulinemia is the driver of all metabolic diseases!
What if I'm prediabetic and have low triglycerides? What does it mean?
@nohasamir3134, maybe because too much fructose in your body, you may listen to dr Robert Lustig interview with dr dom d’agostino, the title how to avoid insulin resistance and why its important, they discuss about a guy name sami inkinen who is thriatlon athlete and work out 5 hours a day but got pre diabetes because of fructose
T3 , t4 , iron, hemoglobin , vitamin D , B vitamins ... And testosterone .. would be where I'd start .... Your hormones control everything ..
Fasting Insulin is THE most important and key blood marker which provides a clear picture of metabolic Health.
Why did they miss this?!
at 1:40 , she mentions the reason is choosing these because vast majority of metabolically unhealthy people use these parameters based on some studies over past 5 years.
To me, it does not make sense to use parameters , just because most of unhealthy Americans have used them. Meh! Lousy method!
Of course, these parameters also are good to know about health, but, 'Fasting Insulin' levels indicates ones health level more incisively; also, one should be aware of 'correct range' within which it (Fasting Insulin) must be ( not the medical industry touted vast ranges)
If everyone knew this information the medical system would go broke. So when you really think about it we’re kept in the dark about health as with a lot of other things in life. Notice how defensive people get when you educate yourself and start conversations that push back? Could be health, politics, work methods you name it. How often am I told “well, you’re not a doctor”. I love it. It’s actually a person telling me I wasn’t supposed to learn this stuff. It’s only for doctors to know. I guess im not allowed to get smart? Well tough. They don’t own the market on learning about health. Actually the more I know about health, the easier it is for my doctor to help me when I have a real problem. When I visit my doctor now he simple asks what labs I’d like done for this visit. He may ask why I want something done or suggest it’s not really necessary but I generally get the labs done that I’d like to review for myself. Doesn’t mean I won’t get a message like “you should be on a statin”. That’s his job to suggest that info. It’s my decision whether or not to go with it. How do I know this. Education!
Nobody is getting there triglycerides in the 50s. Maybe a tiny , tiny percentage. 60-70 in my opinion is optimal ..
lol, mine 43
Mine is 40.
Mine is 41
I so disagree with her about fasting glucose. I am Carnivore, and my *highest* glucose measure of a day can be my morning fasting, because that is after my liver produces glucose in order for me to start my day. I'd say that: (1) highest glucose of the day is more important - which for me can be 120, and (2) focus on insulin levels, not glucose.
Ok, thanks. But still, at this point I believe that the community needs a more nuanced, mechanistically clear framework for understanding this kind of topics. I don’t want to sound tedious or anything, but: it’s boringly obvious that having fasting glucose AND fasting triglycerides in the “high normal” range is not good. Let’s try to address different scenarios; for example, what about slightly elevated fasting glucose AND normal / low triglycerides? How to interpret this type of situation? This is just an example, of course. We need tools and ultimately a framework for understanding THIS type of scenarios.
Myleoperoxidase, MPO
HDL is it 50 for women, or above 50?
Above
I don't see why HDL is relevant. We know low HDL is NOT harmful. We also know high HDL is NOT protective.
High HDL can indicate autoimmunity.
8:12 amd they will say, lets check you back here in a year
Ok
Fasting insulin
We never heard what the rest of the blood test she would recommend…..
He asks for a reminder of what HbA1C is at 4:24. The answer is at 9:05. WAY, WAY too much talking.
She talks with vocal fry. Room for creeEEAaam ? :D
Love her. But the fry grates my soul....
My triglycerides are at 40. Not being sarcastic at all, but is that too low?
No
Fasting Insulin
You can order Nutrition Genome yourself, don’t need a doctor. $359
i heard if you have a high LDL its actually healthy since its transporting more fats
Source?
It’s only healthy if you also have a low triglyceride:HDL ratio. If not, the LDL is dysfunctional and also getting stuck in blood vessels.
❤❤❤
STAY AWAY from Doctors folks. Work hard at you're lifestyle and diet. Buy your tests online cheaply. I run her labs for about $75
Dr. Casey Means needs to work on better explaining in simpler way the specific blood test we have to request. I think that this guest was not informative at all. I usually enjoy your video but not this one. Sorry.
When you said that your audience hates this, you were not kidding. You literally turned what should have been a ninety second video into eleven minutes and twenty nine seconds. Why do you keep doing this?!?!?!?! It's reached the point where I rarely watch your videos to the end.
Make your own videos.... maybe you can be a star.
a health video that actually wants to steal 10 minutes of your life to get some $$
Maybe the best answer for you is to not even start watching them
@@eamonnwits a 3 hour podcast filled with amazing knowledge FOR FREE. Some of us love the depth. Not everything needs to be a tik tok video
How are you going to explain these biomarkers in 90 seconds?
I don’t want a list of biomarkers, I want to know what they mean. Also, I would like to see an even longer video with scientific analysis to make sure it’s not just an “opinion”. A mere list of biomarkers doesn’t give any confidence to apply this information in my life.
I hate Andrew Huberman
Some errors in what she said. Per UNC study of Araujo et al the optimal waist size in men was less than 40 inches not less than 35 inches as she said.
relisten to it. That's what she said, less than 35 for women and less than 40 for men