The Most Common Allergy In The World

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  • เผยแพร่เมื่อ 23 พ.ย. 2021
  • The urushiol molecules in poison ivy have the ability to trigger a harmful immune response in most people because the immune system mistakenly labels them as a threat.
    LEARN MORE
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    To learn more about this topic, start your googling with these keywords:
    - Allergy: A damaging immune response by the body to a substance.
    - Allergen: The substance that causes the allergic reaction.
    - Urushiol: The allergen in poison ivy and poison oak.
    - Allergic Contact Dermatitis: An allergic response caused by contact with a substance that causes rash or lesions at the site of the exposure.
    - Langerhans Cell: An immune sentinel that lives in the epidermis of the skin but can travel to nearby lymph nodes.
    - Helper T Cell: A type of white blood cell that activates immune responses in the body.
    - Thrush: A white skin rash caused by the fungus candida.
    - Anaphylaxis: A whole body allergic reaction that can include throat swelling.
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    REFERENCES
    **************
    Khaled Marwa, Noah P. Kondamudi (2021) Type IV Hypersensitivity Reaction. StatPearls. Retrieved from: www.ncbi.nlm.nih.gov/books/NB...
    John Barrat (2014), A Poison Ivy Primer, Smithsonian Retrieved from: www.si.edu/stories/poison-ivy...
    Florian Winau (2021) Personal Communication. Department of Pediatrics, Harvard Medical School.
    Tiffany Scharschmidt (2021) Personal Communication. Department of Dermatology, UCSF Medical School.
    Yesul Kim, Alexandra Flamm, Mahmoud A. ElSohly, Daniel H. Kaplan, Raymond J. Hage Jr, Curtis P. Hamann, and James G. Marks Jr (2019). Poison Ivy, Oak, and Sumac Dermatitis: What Is Known and What Is New? Dermatitis. 30: 3 (183-190). Retrieved from: journals.lww.com/dermatitis/A...
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  • @MinuteEarth
    @MinuteEarth  2 ปีที่แล้ว +142

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    • @itismethatguy
      @itismethatguy 2 ปีที่แล้ว +3

      I thought this vid wouldn’t get tons of views why are they so less compared to the likes? If we are a member, does the view not count if we watch it earlier than the TH-cam release?

    • @Xena_bruser_willow
      @Xena_bruser_willow 2 ปีที่แล้ว +3

      Cool

    • @stormfiretheog9183
      @stormfiretheog9183 2 ปีที่แล้ว +2

      Wow first time being early :0

    • @ThatCuriosity
      @ThatCuriosity 2 ปีที่แล้ว +3

      @@itismethatguy yeah I think so

    • @itismethatguy
      @itismethatguy 2 ปีที่แล้ว +1

      @@ThatCuriosity oh that makes sense

  • @Pyronaut_
    @Pyronaut_ 2 ปีที่แล้ว +2193

    I was never told and never even considered that the reaction to Poison Ivy was an allegy, but it makes so much sense that it is.

    • @pushyasaieraag2141
      @pushyasaieraag2141 2 ปีที่แล้ว +16

      @@judulbaru2607 BEGONE BOT!

    • @m136dalie
      @m136dalie 2 ปีที่แล้ว +5

      It's not, it's a delayed hypersensitivity. Allergies are immediate reactions.

    • @Tsum1231
      @Tsum1231 2 ปีที่แล้ว +5

      allegy

    • @nonnativenarnian
      @nonnativenarnian 2 ปีที่แล้ว +23

      NOT NECESSARILY
      I get an allergic reaction to shellfish immediately when eating, but the worst of it, the hives that come with eating crab are DELAYED by an hour or more after I stop eating.

    • @LexBlueshell
      @LexBlueshell 2 ปีที่แล้ว +3

      Fun fact, I’m not allergic to poison Ivy!

  • @SupremeLeaderKimJong-un
    @SupremeLeaderKimJong-un 2 ปีที่แล้ว +583

    On a whim, I decided to roll around in some poison ivy.
    It was a real rash decision.

    • @thePronto
      @thePronto 2 ปีที่แล้ว +16

      Since you lost so much weight recently, you had a lot less surface area to worry about. Good job, Jong-un-a!

    • @bug8585
      @bug8585 2 ปีที่แล้ว +8

      Puns!

    • @sandro5535
      @sandro5535 2 ปีที่แล้ว

      Please try eating it and covering your nose with it. North Korea will thank you.

  • @AnonymousFreakYT
    @AnonymousFreakYT 2 ปีที่แล้ว +1292

    My wife has the same reaction to regular English Ivy as to poison ivy. It's super strange - and our kid didn't believe it when he was little. He thought it strange that she couldn't touch the leaf he could. He admitted as an adult that multiple times, he would wipe an English Ivy leaf on something my wife would touch to see if she would immediately break out in a rash.
    Of course, her reaction wasn't instant - it took a couple days. So by the time she broke out in a rash, he had forgotten that he had done it. He only made the connection as an adult. And my wife instantly had an "AHA! That explains all the random rashes I had! I always thought it was that the dog had gotten into it without my knowledge!"

    • @loonloon9365
      @loonloon9365 2 ปีที่แล้ว +192

      I learned that our family had a resistance to poison ivy when I was 6 and the entire neighborhood got it when playing in the woods and I didn't. Talked to a doctor and most Native Americans are resistant.
      The keyword is RESISTANCE, very few people are completely immune, and with repeated exposure you will get it eventually.

    • @KenPapara
      @KenPapara 2 ปีที่แล้ว +34

      The old, it was the dog trick

    • @cheaterman49
      @cheaterman49 2 ปีที่แล้ว +12

      That's a very cute story, thanks for sharing it with us :-D

    • @LadyAnuB
      @LadyAnuB 2 ปีที่แล้ว +11

      This isn't strange, it's your wife's immune system response cranked up to 1000 in contact with whatever molecule's produced by English ivy that's likely similar to urushiol. I have this response as well but at an 11. 😀
      My response goes into high gear when ivy grows new leaves or repairs old leaves. I suspect that this same molecule is produced by redwood trees as they grow new leaves. (I can't tell if one or both cause this reaction as they are both outside my condo.)

    • @justjoking5252
      @justjoking5252 2 ปีที่แล้ว +38

      1. That is evil
      2. That is hilarious

  • @korcommander
    @korcommander 2 ปีที่แล้ว +693

    You ever just roll around in poison ivy just to flex your lack of allergy?

    • @FluoxetinaBelcher
      @FluoxetinaBelcher 2 ปีที่แล้ว +33

      Lmfao please don't... so many idiots out there will try this

    • @HisameArtwork
      @HisameArtwork 2 ปีที่แล้ว +37

      @@FluoxetinaBelcher for science!! XD

    • @MurdocsMinion
      @MurdocsMinion 2 ปีที่แล้ว +148

      You should be careful with that. It is possible to lose your immunity to the allergy, and to go straight into anaphylaxis. This is also the case with things you're "just a little" allergic to.

    • @LofferLogge
      @LofferLogge 2 ปีที่แล้ว +61

      It is also the case that more exposure to poison ivy will make you more likely to develop an allergy to it. So if you want to keep your lack of allergy, it is still a good idea to avoid it when you can.

    • @thany3
      @thany3 2 ปีที่แล้ว +5

      I can't. I don't think it grows around these parts 😎
      Or, I'm one of the 15%, but then I would still have learned about it in school or from my parents, surely...

  • @emmettturner9452
    @emmettturner9452 2 ปีที่แล้ว +463

    Just knowing that the reaction was an allergy I had already guessed that Urushiol was the topic here. I did not realize that it was the most common allergy in the world but I did know that most people were allergic, hence one common plant-source being named “Poison Ivy.”

    • @thany3
      @thany3 2 ปีที่แล้ว +7

      Even so, anything that is poisonous to us, might be harmless to other animals. There might be a fine line between poisons and allergens.

    • @abdullahenaya
      @abdullahenaya 2 ปีที่แล้ว +6

      @@thany3 that doesn't matter. If the substance actually hurts us on its own it's poisonous, even if it's not poisonous to other animals. The line between allergens and poisons is if the immune system reacts to it when it wouldn't actually hurt us, it's an allergy

    • @quoccuongtran724
      @quoccuongtran724 6 วันที่ผ่านมา +3

      @@thany3 in essence: poisons actually harm while allergens only trigger reaction from the immune system for no reason.
      in practice: only a small number of animals are resistant to poisons - the majority of them are vulnerable to poison; meanwhile each allergen only affects a few animals - while other animals are fine with it
      animals that seems unaffected by poisons actually have anti-toxin mechanism inside of them, so for a given poison, only a few animals are resistant to it

  • @SgtSupaman
    @SgtSupaman 2 ปีที่แล้ว +208

    I always knew poison ivy was safe because I was one of the few not allergic to it. Unfortunately, I seem to have developed an allergy to it in more recent years. So what I really want to know is why people can become allergic to things over time. How is our body not tricked by harmless things, but then forgets how to handle them later?

    • @OrigamiMarie
      @OrigamiMarie 2 ปีที่แล้ว +23

      Could be that your body fought off something dangerous and similar to poison ivy, and put those antigens in the bank, so now it gets them out when it sees poison ivy?

    • @Fhantomania
      @Fhantomania 2 ปีที่แล้ว +2

      Or Maybe because Magicc

    • @haloharry97
      @haloharry97 ปีที่แล้ว +10

      It can be the other way around too.

    • @BoyProdigyX
      @BoyProdigyX ปีที่แล้ว +20

      It was the same for me! As a kid I could roll around in the stuff. Now after a little yard work without gloves, I could cut off my hands the itch is so bad haha

    • @NYKevin100
      @NYKevin100 4 หลายเดือนก่อน

      Like the video says, we don't really know for sure. The immune system is really complicated and has a lot of moving parts. We do know that the immune response can be modified through vaccination, but we were only able to figure that out because the immune system was already modifying itself in response to real infections (a vaccine is essentially a "fake" infection).

  • @AverytheCubanAmerican
    @AverytheCubanAmerican 2 ปีที่แล้ว +443

    When poison ivy isn't actually poisonous at all:
    *So that was a F'ing lie*

    • @Psychol-Snooper
      @Psychol-Snooper 2 ปีที่แล้ว +35

      Yeah, well the sabre tooth tiger... was not a tiger! Arabic numerals... came from India! Strawberries... not berries!
      Bananas however are berries, so... that evens it all out.

    • @OhhCrapGuy
      @OhhCrapGuy 2 ปีที่แล้ว +34

      @@Psychol-Snooper Strawberries aren't berries?! That's bananas!

    • @christopherfeatherley
      @christopherfeatherley 2 ปีที่แล้ว +11

      Language helps mold our opinion towards things, often saving us, too. By calling it "poison" ivy, it probably helps deter most people from it. I know it has for me

    • @Psychol-Snooper
      @Psychol-Snooper 2 ปีที่แล้ว +3

      @@christopherfeatherley Allergy ivy would not have been a very good name given the word has only been in use since the 1900s.

    • @Psychol-Snooper
      @Psychol-Snooper 2 ปีที่แล้ว +2

      @@OhhCrapGuy It's also not an ivy!

  • @ABCD-rm5vo
    @ABCD-rm5vo 2 ปีที่แล้ว +289

    Fun fact, urushiol can also be found in the skin of mango and the shells of pistachios and cashews.

    • @bug8585
      @bug8585 2 ปีที่แล้ว +10

      And?? Do people get allergies from those too?

    • @riverfortune1990
      @riverfortune1990 2 ปีที่แล้ว +68

      @@bug8585 Def yes. Bought my first mango and liked it so much I used my teeth to scrape as much fruit as I could off the peel.
      Rash all around my mouth the next day. 😓

    • @theamazingsolt
      @theamazingsolt 2 ปีที่แล้ว +23

      I pretty much need to actively avoid cashews and pistachios for this reason. Never had an issue with mango tough 🥭 🤔

    • @ABCD-rm5vo
      @ABCD-rm5vo 2 ปีที่แล้ว +21

      @@bug8585 Dermatologically, yes. Contact dermatitis is relatively common in these foods when peeling or shelling.

    • @sackboy1665
      @sackboy1665 2 ปีที่แล้ว +2

      @@bug8585 My mom does

  • @Curtistopsidae
    @Curtistopsidae 2 ปีที่แล้ว +169

    Worth mentioning that the type of allergy from urushiol is different than the classic food allergy. It's a type IV hypersensitivity reaction which tends to only cause symptoms after 12+ hr vs most food allergies which are type I hypersensitivity reactions and cause symptoms within the hour

    • @m136dalie
      @m136dalie 2 ปีที่แล้ว +3

      And type IV hypersensitivity isn't considered an allergic reaction

  • @princetandukar9290
    @princetandukar9290 2 ปีที่แล้ว +62

    I love how pickachu is eating poison ivy 2:11

    • @randomperson8663
      @randomperson8663 2 ปีที่แล้ว +1

      Yeah it's so cute! 😄

    • @eglol
      @eglol 3 หลายเดือนก่อน +1

      I'm wearing Pikachu merch rn and loved seeing it in this video

  • @emperium108
    @emperium108 2 ปีที่แล้ว +113

    Huh, I always assumed everyone would be adversely affected by poison ivy. Interesting to know it has no effect on some people.

    • @caesar7734
      @caesar7734 2 ปีที่แล้ว +2

      I never came into contact with it, yet

    • @ConstantChaos1
      @ConstantChaos1 2 ปีที่แล้ว +6

      I used to grow it as a house plant (I lived in a bad neighborhood and since I don't react it seemed the logical thing to do)

    • @bakrobertjohnston4889
      @bakrobertjohnston4889 2 ปีที่แล้ว +1

      The lucky ones

    • @RoccosVideos
      @RoccosVideos 2 ปีที่แล้ว +2

      I’ve never had a reaction to it but have come into contact with it. I don’t test my luck though. It’s not something I’d do intentionally.

    • @alsaunders7805
      @alsaunders7805 หลายเดือนก่อน +2

      I'm one of them, I used to pick it and chase my cousins with it. 🌿🤔🤓🍻

  • @sciencenerd7639
    @sciencenerd7639 10 หลายเดือนก่อน +10

    The summer before kindergarten I had a real bad interaction with poison oak. Later at school, when asked about allergies, I told kids that "I'm allergic to poison oak". Other kids said, no, you're dumb, that is not an allergy because everyone reacts to poison oak. Today I found out that I was right all along!

  • @yotammor9542
    @yotammor9542 2 ปีที่แล้ว +61

    I am happy that i understand allergys now

    • @Prelmable
      @Prelmable 2 ปีที่แล้ว +3

      I'm sad that you don't know how to spell allergies correctly.

    • @vallauritz311
      @vallauritz311 2 ปีที่แล้ว +3

      You don’t, this was horribly explained

    • @bug8585
      @bug8585 2 ปีที่แล้ว +3

      @@vallauritz311 How so?

  • @johnsteinat5213
    @johnsteinat5213 2 ปีที่แล้ว +157

    I wonder if there could be a related benefit that we would lose if we lost that allergy. If it only affects the primates most closely related to us and the rate is so high, it seems like that's only possible if not having the allergy was detramental to the point of almost destroying the gene. Or maybe, because poison ivy grows in North America and Humans evolved in Africa, it's just coincidence, like lacking the ability to make vitamin C

    • @HisameArtwork
      @HisameArtwork 2 ปีที่แล้ว +38

      some primates have a higher resistance aids, malaria and flu. the vid did say it's similar to tuberculosis and the candida fungus which lives on human skin. Maybe those two disease would be a bigger issue if we didn't overreact to their presence? Tuberculosis had a 12% death rate, ebola can have up to 92%. Maybe tuberculosis could have been higher?

    • @MrBlack0950
      @MrBlack0950 2 ปีที่แล้ว +27

      My guess is its a coincidental result of genetic bottlenecking. The allergy mutation was part of a small set og genes found in a reduced population, probably early on in primate evolution, and just stuck around. It might have a benefit, but it could just as likely be a quirk of evolution.

    • @Fritzafella
      @Fritzafella 2 ปีที่แล้ว +14

      My intuition is its just an accident.
      The reaction is unlikely to result in being removed from a gene pool and thus wouldn't get stripped away over time.
      Though completely removing the ability to detect the chemical would have a negetive effect on our imminue system as then a few actually problamatic things could get flagged as OK after being mistaken as the harmless chemical.

    • @andresv.8880
      @andresv.8880 2 ปีที่แล้ว +5

      Apparently native Americans are resistant to the allergic reaction so it may just have evolved because it was a foreign substance to the rest of the world

    • @IHateUniqueUsernames
      @IHateUniqueUsernames 2 ปีที่แล้ว +10

      It could be one of those things that we simply did not select against because it is of no consequence if we do or not, in the greater scheme of things. There's no selection pressure for the immune system to uniquely identify this one molecule as an exception to the way the body detects and defend against actual threats.

  • @JesusMartinez-rr2ry
    @JesusMartinez-rr2ry 2 ปีที่แล้ว +56

    I chuckled when you also included Bigfoot as one of humans' close relatives who are also allergic to the urushiol in "poison" ivy.

    • @mrnice4434
      @mrnice4434 2 ปีที่แล้ว +7

      Good to know if a Bigfoot attacks you just throw some poison Ivy at him/her

    • @hebl47
      @hebl47 2 ปีที่แล้ว +8

      Well, I haven't met a single Bigfoot who wasn't alergic to poison ivy, so I think it makes sense they included it.

    • @hannya6552
      @hannya6552 2 ปีที่แล้ว +4

      @@mrnice4434 thank you for respecting big foot's gender

    • @garethbaus5471
      @garethbaus5471 2 ปีที่แล้ว +1

      Well if bigfoot were real it would probably have been in north America far longer than even the native Americans (who are already less likely to be sensitive) so bigfoot would probably be immune.

    • @no1uno388
      @no1uno388 2 ปีที่แล้ว +1

      @@mrnice4434 have a word for you "they" amazing isnt it?

  • @Darknimbus3
    @Darknimbus3 2 ปีที่แล้ว +20

    Actually urushiol in high quantities, such as found in the cashew shell (cashew is in the poison ivy family btw), can be very toxic. It’s why you never see cashews with the shell on in the market, and why “raw cashews” aren’t actually raw (in the culinary sense).

    • @Owen_loves_Butters
      @Owen_loves_Butters 2 ปีที่แล้ว +1

      Well literally everything can be toxic

    • @exosproudmamabear558
      @exosproudmamabear558 3 หลายเดือนก่อน

      It is about the amount even water can be poisonous if you drink enough.

  • @cruros9084
    @cruros9084 2 ปีที่แล้ว +22

    Ironically just learned about this type VI hypersensitivity in my immunology class a few weeks ago.

  • @cinnamonsugarcourtney6073
    @cinnamonsugarcourtney6073 2 ปีที่แล้ว +13

    I'm not allergic to urushiol. :3 I've never had an outbreak due to it... but my brother and little sister are very allergic to it. I know because I was leading a walk with my sister and she walked after me and by the time our walk was over she had broken out due to poison ivy, but even though I was wearing shorter pants and things nothing happened to me. We were going the same path and she was right behind me, not next to or anything.

  • @kokiriboy99
    @kokiriboy99 2 ปีที่แล้ว +46

    Hi, so, sure, it's an "allergy" in the sense that it's a hypersensitivity reaction. But this is a delayed-type/CD4+-mediated/type IV hypersensitivity and it differs a lot from the IgE-mediated/type I hypersensitivities we usually call "allergies," like the reactions to peanuts and bees and pollen and cats, including the ones that lead to anaphylactic shock. Your video explains how this type IV hypersensitivity plays out, but you mislead your viewers into thinking this is also the mechanism for type I reactions. It is not.

    • @floresarmando4318
      @floresarmando4318 2 ปีที่แล้ว +1

      I'm glad someone else noticed

    • @jasonreed7522
      @jasonreed7522 2 ปีที่แล้ว +2

      As someone for whom this topic is not my field (electrical engineering), my general understanding is that an "alergy" is the immune system messing up and attacking harmless FORIEGN antigens and that autoimmune diseases are the immune system messing up and attacking YOUR OWN antigens.
      I understand that the immune system is more complicated than words can state so obviously my definitions are lacking a lot of nuance. However, i also don't expect the general public to understand the nuance of Maxwell's equations and how they can be used to descibe any EM field/device/system. Sometimes just knowing that sticking a fork in an outlet can kill you is sufficient.
      My point is complaining about a 3min video not differentiating between 2 very specific chemical event chain types classified as type 1 and type 4 hypersensitivities being a true "alergy" or not when the point is that its your immune system hurting you and not the compound itself (alergy vs toxin), is a little nitpicky.

    • @m136dalie
      @m136dalie 2 ปีที่แล้ว +2

      Allergies only apply to type I hypersensitivity, type IV reactions are not considered allergies so the video is wrong.

    • @m136dalie
      @m136dalie 2 ปีที่แล้ว +8

      @@jasonreed7522 It's not nitpicky it's a fact that type IV reactions aren't considered allergies. Otherwise host vs graft disease would be considered an allergic reaction, something it very clearly isn't since it can take months to kick in. Same thing with type I diabetes, which is also the same mechanism.

    • @bosstowndynamics5488
      @bosstowndynamics5488 5 วันที่ผ่านมา

      ​@@m136dalieI know this comment is old, but it really bothers me when I see someone who is so confidently, arrogantly, yet completely, wrong. Actual healthcare resources do not distinguish between "allergy" and "type IV hypersensitivity" because "allergy" is a longstanding description that in modern usage has come to refer mostly to immune system mediated reactions to what would otherwise be harmless exposures. Some resources I could find even referred to the classification scheme that type IV is a type of as the classification of types *of allergy*. The fact that many of the most common forms of allergy people discuss day to day are caused by type I reactions does not in any way somehow make common type IV mediated allergies like contact dermatitis and zinc allergies not count, any reasonable person, including pretty much any specialist in the field, would call the latter allergies.

  • @scaboodle
    @scaboodle 2 ปีที่แล้ว +6

    This video is a little misleading. At 1:22 you say this is the same phenomenon as other allergies. This isn't true as other allergies are IgE mediated (i.e. caused by antibodies and generally only in reaction to proteins!) and known as type I hypersensitivity. The process you have described for urushiol is a type IV hypersensitivity. Which is arguably not an allergy at all!

    • @floresarmando4318
      @floresarmando4318 2 ปีที่แล้ว

      After reading a lot of comments comparing "allergy" to poison ivy to true allergens, I agree it's misleading.

  • @handsomeman-child8751
    @handsomeman-child8751 2 ปีที่แล้ว +5

    I think I remember MythBusters doing an episode about poison ivy cures but almost the entire team were either immune or dangerously allergic.

  • @iceman101101101
    @iceman101101101 2 ปีที่แล้ว +19

    Fun fact: that molecule is also found in the skin of mangoes. Found out the hard way I'm allergic to my favorite fruit🙃

    • @SgtSupaman
      @SgtSupaman 2 ปีที่แล้ว +1

      I can confirm this is true. Do not peel mangoes fresh off the tree with your teeth. It makes for a few very bad days afterwards....

    • @Ikajo
      @Ikajo 2 ปีที่แล้ว +2

      You should be able to eat them peeled though. My sister can't eat mango from the skin but she can if the skin is removed

    • @iceman101101101
      @iceman101101101 2 ปีที่แล้ว

      @@Ikajo I've heard this too and makes logical sense. I was just traumatized with my experience so I've sworn off of them. Not taking any chances ha.
      Had hives all over my face right when I started a new job in a hospital lol Tons of scared faces followed by profusely apologizing and explaining contrary to looks, I dont have some horrible disease lol

    • @Ikajo
      @Ikajo 2 ปีที่แล้ว +2

      @@iceman101101101 Food trauma is real, so I get it. I discovered less than two years ago I'm very likely allergic to sweet melons, like honeydew. Which is rather annoying since I really like green honeydew melon. But it did certainly explain a lot.

    • @SgtSupaman
      @SgtSupaman 2 ปีที่แล้ว

      @@iceman101101101 , it's understandable that it would make you hesitant (I wound up wearing a bandana across my face to cover up the nastiness; and this was long before Covid19, so covering my face was an obviously weird thing back then), but I will eat fully peeled mangoes with no problems (only after I understood that it was the peel that was the problem). Hopefully, you can get back to it, because mangoes are too good to be missing out on.

  • @cheaterman49
    @cheaterman49 2 ปีที่แล้ว +19

    I'm surprised you didn't mention it (so maybe it's wrong?) but I thought the itchy reaction we get from mosquito bites are also essentially an allergic reaction to the anti-coagulant substances in their saliva? Thanks for the video :-)

    • @Soken50
      @Soken50 2 ปีที่แล้ว +3

      I assumed the itchiness was from pathogens carried by the mosquito when biting and the immune system flaring up once the anesthetic wore off

    • @erikkarlson5902
      @erikkarlson5902 2 ปีที่แล้ว +3

      It is an allergic reaction, I know because I am not allergic (:

    • @cheaterman49
      @cheaterman49 2 ปีที่แล้ว +3

      @@erikkarlson5902 Oh so your body literally doesn't react to mosquito bites? That is pretty cool!

    • @erikkarlson5902
      @erikkarlson5902 2 ปีที่แล้ว +8

      @@cheaterman49 yeah, no red at all, no bump either. I literally can't even tell where they bit me once I forget. I read in a book once that about 1/10,000 of us aren't allergic to mosquitos, and I just happen to be one of those.

    • @jasonreed7522
      @jasonreed7522 2 ปีที่แล้ว +9

      The reaction to mosquito bites (and similar) is caused by the molecule Histamine, which is an immune system "hormone?" That triggers inflammation and itchyness, so many alergens trigger it as well as actual dangers.
      I would classify the reaction to mosquito anticoagulent spit to be a justified reaction and not an alergy based on the fact that insect bites are not harmless and even if the anticoagulant itself isn't a danger all the pathogens mosquitoes famously carry are (Malaria, dengue fever, west nile, ect). So you do want to be aware that you were bitten by them and react to it, even if you are from an area where these diseases are not common.
      I remember seeing a video on how it would take 10,000 bites daily to become and maintain immunity to their spit (desensitized) and they then immediately explained why doing so would be a terrible idea (beyond the insane daily bites) mostly being similar to how having 0 pain receptors is problematic, you wont know when you get hurt.

  • @allthegoodthings707
    @allthegoodthings707 2 ปีที่แล้ว +18

    That was very interesting. I am now wondering why we can develop allergies to things. If we have come into contact with something that our body already knew didn't hurt it, how does further exposure teach it that it is bad?

    • @7W33K
      @7W33K 2 ปีที่แล้ว +3

      It's called sensitization. If your immune system finds something it doesn't recognize and decides that its bad, but that thing is no longer around by the time you immune system has developed antibodies, it will only react to it the next time you encounter that thing. Somewhat oversimplified, but you get my point.

  • @medkitty
    @medkitty 2 วันที่ผ่านมา

    I love how you drew the dendritic cell!

  • @TheTerranInformed
    @TheTerranInformed 2 ปีที่แล้ว

    I had no idea some people weren’t allergic to poison ivy and oak!
    Really cool video!

  • @Alpha13Wolf
    @Alpha13Wolf 2 ปีที่แล้ว +19

    There’s also the fact that your first encounter with the stuff won’t result in any symptoms at all. Then, any encounter afterward will. Also there really isn’t an immunity to it, it’s just some haven’t experienced their first sensitizing encounter with it, as well as those who have a very mild response to it that remedies itself quickly; before you even notice it. Unlike many allergies, stings excluded, it’s a persistent, lifelong, allergy that does not decrease with repeated exposure.
    Bee stings are the only allergy that worsens with repeated exposure.

    • @SqueamishNerd
      @SqueamishNerd 2 ปีที่แล้ว

      Latex allergy also worsens with repeated exposure.

  • @managingbusiness141
    @managingbusiness141 2 ปีที่แล้ว

    Thank you for another great video!

  • @faizkroller1996
    @faizkroller1996 2 ปีที่แล้ว

    1:37
    That sigh is just the best

  • @Ggdivhjkjl
    @Ggdivhjkjl 7 วันที่ผ่านมา +2

    That handcuff guessing method is so unfair.

  • @NoodleySnek
    @NoodleySnek 5 วันที่ผ่านมา

    great another thing to add to my long list of allergies 😭😭😭
    awesome video though!!!

  • @modernkennnern
    @modernkennnern 2 ปีที่แล้ว

    That was a very good explanation of allergies, wow

  • @namedtruman
    @namedtruman 2 ปีที่แล้ว +5

    no wonder i never got a rash by touching poison ivy holy crap

  • @9SMTM6
    @9SMTM6 2 ปีที่แล้ว

    Would you consider making a video about the Syrinx in birds, why we think they developed it, etc? It is the primary voice box of birds, more important for their sounds than the larynx that both we and birds have.

  • @hualiu7509
    @hualiu7509 2 ปีที่แล้ว

    I like this video so much . If you don't mind , I would like to ask your permission to share this video to the other website in China for the embarrassing reason that TH-cam is blocked from accessing in China . Of course , I will give sources of the original website . Thank you very much .

  • @zacthebold5136
    @zacthebold5136 2 ปีที่แล้ว +6

    I had reactions as a child, teen, and young adult. In the last few years though, with more frequent exposure I believe I am completely bomb-proof to urushiol. I ran a weed-eater through a mini-grove of it wearing shorts and sandals.
    No effect!

  • @frankierodriguez866
    @frankierodriguez866 2 ปีที่แล้ว

    Thanks for this video

  • @stolenshortsword
    @stolenshortsword 2 ปีที่แล้ว

    the animated version of urushiol looks so nice and polite

  • @Minty1337
    @Minty1337 2 ปีที่แล้ว +5

    that explains my immunity to poison ivy

  • @Hiro_Trevelyan
    @Hiro_Trevelyan 4 วันที่ผ่านมา +1

    Nobody:
    Human Tcell : I hate this thing and so will you

  • @PlutoTheSynth
    @PlutoTheSynth หลายเดือนก่อน

    2:11 i LOVED that pun lmao

  • @RabbitNeckyBecky
    @RabbitNeckyBecky วันที่ผ่านมา

    *goes outside and touches poison ivy to see if I'm allergic*

  • @Michael_Pereira
    @Michael_Pereira 2 ปีที่แล้ว

    1:59
    Lol I didn't realize Pikachu qualified as an "other animal" 😆

  • @aholesahole
    @aholesahole 2 วันที่ผ่านมา

    I didn't used to be allergic to poison ivy, now I get reactions every time I work in the yard. It's insane.

  • @astro6512
    @astro6512 2 ปีที่แล้ว +1

    Wow, that makes sense!
    Also, my dad was immune to poison ivy, does this mean he would get tuberculosis or something more easily since his body would brush it off?

  • @nightmarestreet5862
    @nightmarestreet5862 2 ปีที่แล้ว

    Loved it!

  • @myozeka
    @myozeka 2 ปีที่แล้ว +9

    I think it’s the first time I hear you doubt when making a pun, such is the delicate topic of allergic reactions

  • @user-ml3hl6vr4t
    @user-ml3hl6vr4t 2 หลายเดือนก่อน

    I can grasp stinging nettles without issue. Found out this was strange at a family reunion vacation. I was itching from my laparoscopy hysterectomy scars itching while healing. An aunt commented that I must have gotten near the nettles by the hot electric wire fence. I walked over, grabbed a handful like I had done for years, and turned back to her. This wasn’t my problem…

  • @magolor2706
    @magolor2706 3 วันที่ผ่านมา

    I was so close. I was SO CLOSE to having no known allergies, I was literally never sick from anything.
    But then hayfever gives me breathing troubles in all the warm times of the year

  • @lancelouis3609
    @lancelouis3609 2 ปีที่แล้ว +1

    Man, MinuteEarth's videos are not complete without the puns and the pokemons in the background 😆

  • @affanafrizalgani9494
    @affanafrizalgani9494 2 ปีที่แล้ว

    Really love the animation

  • @treehugger0241
    @treehugger0241 2 ปีที่แล้ว +2

    I remember a mythbusters episode that wanted to test if vodka worked as a poison oak cure. The premise was simple: Expose someone to poison ivy, treat one area with commercial cream, one with vodka, and one with nothing as a control.
    Took them six people, three of whom were allergic in the past, before someone finally got a reaction.

    • @jasonreed7522
      @jasonreed7522 2 ปีที่แล้ว

      I remember that, it must have felt like such a strange coincidence/ very "unlucky" that it took so many trys just to find someone actually allergic to a famous "no touchy" plant.

    • @treehugger0241
      @treehugger0241 2 ปีที่แล้ว +2

      @@jasonreed7522 That seemed to be a common theme in the show; if a plan was simple on paper, it was never so simple in practice.

    • @jasonreed7522
      @jasonreed7522 2 ปีที่แล้ว

      @@treehugger0241 that was definitely the norm on that show, and true to how real experimental science goes. But atleast a few myths went fairly smoothly like the water heater rocket myth (actual hazzard, dont defeat the safeties of your appliances) or the florescent nasal drip dinner party with blacklight reveal (part of the flu special episode, also very concerning to germaphobes)

  • @PramkLuna
    @PramkLuna 2 ปีที่แล้ว +16

    Molecule not attached to you: lands on skin
    Urushiol: And I took that personally

  • @marmite400
    @marmite400 2 ปีที่แล้ว

    I love the Big Foot you snuck in there!😁

  • @JimsyFlimsy
    @JimsyFlimsy 3 วันที่ผ่านมา

    I didn't know Pikachu enjoyed eating poison ivy.

  • @erikkarlson5902
    @erikkarlson5902 2 ปีที่แล้ว +7

    @MinuteEarth aren't mosquitos a far more common allergy? I believe over 99% of people are allergic. In fact it's so common, unless you are one of the few people who aren't allergic (like myself) you probably won't even have heard it is an allergic reaction.

    • @WanderTheNomad
      @WanderTheNomad 2 ปีที่แล้ว +1

      You mean their saliva?

    • @erikkarlson5902
      @erikkarlson5902 2 ปีที่แล้ว +5

      @@WanderTheNomad yes exactly. I read in a book once that it is estimated that only around 1 in 10,000 people do not have any allergic response to their saliva. Never found another figure to back that up, but I've never met anyone besides myself yet.

    • @NeoRazor
      @NeoRazor 2 ปีที่แล้ว +2

      Nobody is allergic to mosquito bites. Their bites itch because their proboscis is barbed like a harpoon, so when they remove it, the barbs rip and irritate your skin on a microscopic scale. That's why the bites hurt the least if the mosquito is left undisturbed for the duration of the bite, and is allowed to carefully remove their proboscis.

    • @reklessbravo2129
      @reklessbravo2129 2 ปีที่แล้ว

      I remember not being allergic to mosquitoes. That was nice

    • @muse208
      @muse208 2 ปีที่แล้ว +2

      @@NeoRazor I’m not finding anything online about this barbed proboscis thing causing the prolonged itch.

  • @arooobine
    @arooobine 2 วันที่ผ่านมา

    I'm as allergic as anyone else. One time in high school I weed whacked through a thick patch of it and got chopped leaves all over my legs. I ran to the shed and bathed my legs in gasoline. It did the trick! No rash.

  • @fouroverseven7799
    @fouroverseven7799 2 ปีที่แล้ว

    Love this!

  • @coolbojy
    @coolbojy 2 ปีที่แล้ว +2

    I dont know about this video. One of the animals you depticed to happily eat urushiol does seem to make a lot of sneezing sounds. Lots of red rash on their cheeks, too.

  • @johnburns2940
    @johnburns2940 4 หลายเดือนก่อน

    I need to have a SERIOUS talk with my immune system sometime this Spring

  • @innerlocus
    @innerlocus 2 ปีที่แล้ว

    So, does knowing that we don't need to react to poison ivy can we do a placebo reaction?

  • @AdeleiTeillana
    @AdeleiTeillana 2 ปีที่แล้ว +1

    My mom, brother and I are all not allergic to poison ivy, but my sister and dad are. Once in the fourth grade I got some leaves and was rubbing them all over my arms. This boy wouldn't believe it was poison ivy so he grabbed them and did the same. He couldn't even come to school the next day, lol. On the one hand, that was mean of me, but on the other hand, I did honestly tell him it was poison ivy, he just wouldn't believe me. 🤣

  • @johndoe-fd7rd
    @johndoe-fd7rd 2 ปีที่แล้ว

    Next time doctor askes if I have any allergies, "no" will not be my answer.

  • @sandwich2473
    @sandwich2473 2 ปีที่แล้ว +1

    Is teargas the same then?
    I hear that some people are immune to that as well

  • @vinnieg6161
    @vinnieg6161 2 ปีที่แล้ว

    the allergies I get from regular grass pollen is absolutely insane sometimes, I can't even function anymore

  • @cheese.6412
    @cheese.6412 2 ปีที่แล้ว +3

    Wait what

  • @sadieandbean
    @sadieandbean 4 หลายเดือนก่อน

    When I was a kid I was carrying around these sticks/leaves and my father freaked out because it was poison oak but I never had a reaction. I do have some skin allergies to different health and beauty products though.

  • @l3176l
    @l3176l 2 วันที่ผ่านมา

    I may be allergic to mushrooms, I may be allergic to penicillin, but I… have to be the one to remove intruding poison ivy from certain areas of the yard.
    Bit of a double-edged-sword that.

  • @CosmicAggressor
    @CosmicAggressor 3 หลายเดือนก่อน

    I actually became almost entirley imune to poisin ivy in the last few years. These days the area just stiffins a bit and sometimes gets a bit red. But there is none of this nonsense with itching, swelling, and small portions of skin actually sluffing off like I used to have.

  • @paulbork7647
    @paulbork7647 2 ปีที่แล้ว

    Well done, cute and informative.

  • @urtiyayeah1946
    @urtiyayeah1946 2 ปีที่แล้ว +1

    Homework:*cough*
    You dare challenge me foolish mortal?

  • @Warrenbowser3
    @Warrenbowser3 2 ปีที่แล้ว

    So would an epipen get rid of a poison ivy rash? (I'm not allergic to anything I don't know if that's what epipens do)

  • @overloader7900
    @overloader7900 2 ปีที่แล้ว

    Scorched earth tactics is super effective!

  • @ThisIsYou36
    @ThisIsYou36 4 วันที่ผ่านมา +1

    I don't know if I'm allergic to poison ivy or not, should I test it out?

  • @qazinoorwasi
    @qazinoorwasi 2 หลายเดือนก่อน

    In my school's backyard, there was a wild bush with pinkish and green color flowers that looked like closed spherical buds.
    We were told we'd go blind if we touch those flowers. Nevertheless, nobody did touch them.
    But that's still a mystery in my head.

  • @winstonbritto2789
    @winstonbritto2789 2 วันที่ผ่านมา

    Okay. Now you've just created an urge to touch Poison Ivy to see if I'm part of the 15% that "not allergic".

  • @IcantThinkOf_A_Name
    @IcantThinkOf_A_Name 2 ปีที่แล้ว +4

    OMG I LOVE YOUR VIDEOS!!!!!!!!!!!!!!!!!!!!!111111

  • @seatbelttruck
    @seatbelttruck 3 หลายเดือนก่อน

    If urushiol is similarly shaped to tuberculosis, maybe the allergy's so common because it was more beneficial to have a quick, strong response to anything tuberculosis-like than it was detrimental to get a rash.

  • @itsanimepotato
    @itsanimepotato 2 ปีที่แล้ว +3

    Wow I saw this at 1 minute

  • @joyo0076
    @joyo0076 2 ปีที่แล้ว +2

    Yay, I'm a early one
    Great video as always

  • @trevorbrooks7816
    @trevorbrooks7816 2 ปีที่แล้ว +1

    I knew this from a young age cause I'm part of the 15% that don't react to poison ivy! My brother and I were playing hide and seek and accidentally crouched in a patch, his week was ruined, I was unaffected and confused

  • @tymunster
    @tymunster 2 ปีที่แล้ว +1

    I actually knew this, when you have a really bad allergy you learn it

  • @ConstantChaos1
    @ConstantChaos1 2 ปีที่แล้ว

    I dont react to it and it helps a lot as a first responder, I've had to go into fields of poison ivy to get paitents

  • @ICU-X1
    @ICU-X1 5 วันที่ผ่านมา

    2:02 they must really love adding pokemons as animals

  • @Planetmango48
    @Planetmango48 2 วันที่ผ่านมา

    That's interesting... It makes sense.

  • @intrepion256
    @intrepion256 ปีที่แล้ว

    Is MinuteEarth on Nebula? I can’t seem to find it

  • @alto7183
    @alto7183 2 ปีที่แล้ว

    Podría servir en el futuro creo, alergias y similares para ubicar mejor que partes del adn son más biocompatibilidad sobre partes del cuerpo específicas, pues ingerir podría ser inocuo pero este ejemplo de la piel otro, por eso de a poco, la ventaja de ser específico es que no se confunde con otros y permite estudiar mejor como este caso, sugerencia.

  • @MyysticYT
    @MyysticYT 7 วันที่ผ่านมา +1

    I Never new that people get rashes from just touching poison ivy. How rare is it to not be allergic in Europe?

  • @BoyProdigyX
    @BoyProdigyX ปีที่แล้ว

    That's cool! As a child, I wasn't allergic to poison ivy. I thought it was because Native Americans couldn't get it.
    The woods nearby were covered in the stuff some summers, yet I'd be the only one that never got a rash after playing there. Recently, now in my 30's, I cleared up my aunt's overgrown backyard from lots of poison ivy and BOY am I allergic now! I had blisters it was so bad. I get chills thinking of that itch.

  • @deleted-something
    @deleted-something 4 หลายเดือนก่อน

    Gotta try those chances!

  • @klrcats
    @klrcats 2 ปีที่แล้ว +1

    I wish I was allergic to it, people make me get stuff when they lose it in the forest, for example when they kick a soccer ball in a forest I'm always the one to get it because poison ivy doesn't effect me.

    • @ConstantChaos1
      @ConstantChaos1 2 ปีที่แล้ว

      I am lucky enough not to react and it has helped alot as a first responder, I've had pts in fields of the stuff and so I was the one to get them and do hands on care to keep my team safe

  • @JajaofAbuja
    @JajaofAbuja 2 ปีที่แล้ว +9

    "We don't know why the Urushiol allergy is unique to us"?
    Simple.
    Because we named it "Poison Ivy".
    Our body is not stupid 🤣

  • @TLG1255
    @TLG1255 2 ปีที่แล้ว

    I knew this! Had a friend who wasn’t allergic to poison ivy growing up. But is it the same for stinging nettle? Is it the same chemical stuff?

    • @ConstantChaos1
      @ConstantChaos1 2 ปีที่แล้ว

      Naw I dont react to urushiol but I react to nettles, they inject formic acid if I recall correctly

    • @TiggerIsMyCat
      @TiggerIsMyCat หลายเดือนก่อน +1

      No, nettles are basically land (and plant, obviously) jellyfish. They have stinging cells that inject irritant chemicals like histamines, and also irritate just by the action of stabbing into the skin

  • @Noone-of-your-Business
    @Noone-of-your-Business 2 ปีที่แล้ว

    Mission accomplished, mind blown.

  • @Very_Unique_Handle_2
    @Very_Unique_Handle_2 3 วันที่ผ่านมา

    When I was younger I didn’t know everyone got rashes from poison ivy so I said I was “allergic to poison ivy” 😭

  • @jadedrealist
    @jadedrealist 2 ปีที่แล้ว

    So what does that mean for someone who isn't alergic or at least doesn't have a reaction to poison ivy? Am I also more prone to tuberculosis?

    • @ANTSEMUT1
      @ANTSEMUT1 2 ปีที่แล้ว

      Possibly but that isn't the main thing tuberculosis uses to wreak havoc on your lungs.

  • @revanthreddythipparthi9225
    @revanthreddythipparthi9225 2 ปีที่แล้ว

    I have been watching your content from years.
    I love your videos but I have a request.
    Can you make animation with black background (or any colour other than white)?

  • @ComradeCorvus
    @ComradeCorvus 2 ปีที่แล้ว +1

    Imagine being one of the people in that 15% that aren't allergic to poison ivy. If I was, I'd just never tell anyone about it so I can randomly freak people out by grabbing a leaf and rubbing it all over myself.

  • @TheScienceBiome
    @TheScienceBiome 2 ปีที่แล้ว +4

    Urushiol sounds like something you'd see straight out of the lord of the rings

    • @MinuteEarth
      @MinuteEarth  2 ปีที่แล้ว +2

      Not quite as powerful as Anduril, but much itchier :)