cAMP - ATP, ADP, cAMP - Adenylate cyclase - Protein Kinase A - G-protein, Cell Signaling - Physio

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  • เผยแพร่เมื่อ 7 พ.ย. 2024

ความคิดเห็น • 121

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 ปีที่แล้ว +5

    💊🤷‍♂️ Cardiac pharmacology is on SALE:
    www.medicosisperfectionalis.com/products/
    💊🧫 My antibiotics course is on SALE:
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  • @alaynaguzzi2017
    @alaynaguzzi2017 2 ปีที่แล้ว +19

    You have brought forth joy and passion that I have been lacking this semester. Thank you.

  • @mikkit876
    @mikkit876 2 ปีที่แล้ว +10

    I have epilepsy and miss a lot of my lectures due to seizures, your videos have helped SO much in me being able to learn biochemistry and medicine. Thank you! You make it so entertaining as well

  • @ficklepepper
    @ficklepepper 3 ปีที่แล้ว +4

    EXCELLENT resource to put concepts together of what 2 textbook, paid courses and expensive books can offer. After watching your video I feel that I can practically track where the process begins and ends forward and backward. Forever grateful. Thank you

  • @MalynLaReina
    @MalynLaReina 3 ปีที่แล้ว +2

    Of all the videos and articles I read this made the most sense. Thank you for breaking it down, and making it fun with your side comments. Really helped me grasp the concept!

  • @jamierayevalmores3109
    @jamierayevalmores3109 3 ปีที่แล้ว +5

    i love your videos. it makes pharmacology fun and a "lil bit" easier. please keep making more. you're the best

  • @lisagonzalez2902
    @lisagonzalez2902 4 ปีที่แล้ว +9

    I've been searching for videos on cAMP, cGMP, and found some very good ones but I wanted to see if you also had a video on this subject, and I found it! Thanks for your effort. Funny, repetitive, really makes me understand better.

  • @saraxcardoso
    @saraxcardoso 4 ปีที่แล้ว +5

    You are so funny and you expalin these concepts so well and so clearly! I love this video, thank you sooo much 💖🙌🏼

  • @Veteran365
    @Veteran365 2 ปีที่แล้ว +4

    Holy shit!! You are an amazing teacher!

  • @aydaabdolmanafi
    @aydaabdolmanafi 10 หลายเดือนก่อน +3

    In the first three minutes i got all my confusion solved, the confusion that has happened after reading a university pamphlet for hours nonsense!

  • @paulakiaraluna1969
    @paulakiaraluna1969 4 ปีที่แล้ว +2

    I love your videos so much!!! I am preparing for my MCATs and I watch your videos to deeper learn topics. Please keep making more! Thank you for all your help!

  • @najumudhina.m.k3966
    @najumudhina.m.k3966 4 ปีที่แล้ว +12

    Your videos are really unique, its reflecting your hard work and by God Grace, you will reach million subscribers soon

  • @ayeshamuhammad6553
    @ayeshamuhammad6553 4 ปีที่แล้ว +2

    Your videos are simply amazing. I have a much better understanding of many topics including cAMP!

  • @Southerngrl
    @Southerngrl 4 ปีที่แล้ว +3

    I bet the plaquenil video wld get you lots of views esp with zpac! Even though it’s “off label” hard for lay pll to understand the ramifications of these meds! You can explain it so much better for us all!

  • @santoszinga2617
    @santoszinga2617 3 ปีที่แล้ว +3

    I really love this video,that makes sense .

  • @Chris-tg8gr
    @Chris-tg8gr 27 วันที่ผ่านมา +1

    "Pharmacology makes perfect sense once you understand what the flip you're talking about!...." I felt that!!

  • @luciararocha
    @luciararocha 3 ปีที่แล้ว +1

    I can't believe I finally understood this!!!! Thank you so much 💓

  • @Afshu97
    @Afshu97 2 ปีที่แล้ว +2

    Nice explanation thank you so so so much

  • @nhhao_medi
    @nhhao_medi 10 หลายเดือนก่อน +1

    i love the way you make it ez to understand
    From Vietnam with luv ❤

  • @farhaelsharif9317
    @farhaelsharif9317 3 ปีที่แล้ว +1

    thank you for this video its perfect you're saving lives

  • @rania0.1
    @rania0.1 ปีที่แล้ว +1

    ❤ love your vibes How to explain and I love your voice more

  • @cynthianyanda3842
    @cynthianyanda3842 2 ปีที่แล้ว

    Thank you so much! I've been stuck confused and didn't want to watch this video coz it's longer than the other cAMP TH-cam videos by like 15 minutes. But I was confused even after watching them so I wasted my own time and here I am.

  • @sunnrayy11
    @sunnrayy11 หลายเดือนก่อน +2

    this mannnnnnnnnnn is great

  • @jesusbrownies
    @jesusbrownies 3 ปีที่แล้ว

    Everything is soo clear after watching this
    Thank you so muchhh

  • @nermeengamal5441
    @nermeengamal5441 3 ปีที่แล้ว +1

    The way you talk so unique, funny, beautiful. ❤

  • @lisagonzalez2902
    @lisagonzalez2902 4 ปีที่แล้ว +4

    I noticed a mistake at 13:05. You say Ca+ channel blockers 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞 cardiac contractility, however, the drawing states that it 𝐝𝐞𝐜𝐫𝐞𝐚𝐬𝐞𝐬 (this is correct).

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +2

      They decrease contractility.
      Thank you so much for correcting me.

    • @lisagonzalez2902
      @lisagonzalez2902 4 ปีที่แล้ว

      @@MedicosisPerfectionalis I have a question! I'm not very clear on the cAMP effects on Angiotensin? Doesn't it inhibit this process (therefore, causing vasodilation)? I've tried watching that part a few times but I don't understand. Please, enlighten me!

    • @lisagonzalez2902
      @lisagonzalez2902 4 ปีที่แล้ว

      Does cAMP cause both vasoconstriction and vasodilation? Beta-agonists increase cAMP, therefore causing vasodilation. But Beta-blockers cause vasodilation by decreasing cAMP because of the A-T pathway? Why doesn't cAMP *only* cause dilation/relaxation in smooth muscle?

  • @ComPasPharm
    @ComPasPharm ปีที่แล้ว

    Thx. Beautifull lecture!!!

  • @sathvikgowda1348
    @sathvikgowda1348 24 วันที่ผ่านมา

    Hi...at 12:10 you say the cAMP causes vasodilation and decrease BP and also you say..via RAAS pathway vasoconstriction occurs and BP increases. Which one is predominant?

  • @markusguerrero9593
    @markusguerrero9593 2 ปีที่แล้ว

    This is amazing. Thank you!

  • @gamagarcia3037
    @gamagarcia3037 ปีที่แล้ว

    just of curiosity are those receptors receiving information outside the membrane which because of the signal they RECEIVE, the START the process of producing the cAMP? , are they the G protein couple receptors?

  • @Robert___3f
    @Robert___3f 3 หลายเดือนก่อน

    Pessimistically acknowledging the power of a smile.

  • @arunaacharya3849
    @arunaacharya3849 2 ปีที่แล้ว

    PDEs are also of different types...There is PDE1,2,3,4.Could u shed some light on the location?..are they all present in the cytoplasm?

  • @sama_albairmani
    @sama_albairmani 3 ปีที่แล้ว

    INCREDIBLY AMAZINGGGGG

  • @calvinrich363
    @calvinrich363 3 ปีที่แล้ว

    if you use b-blocker, which means b1 receptor is not working, so no stimulation of Gs, so no cAMP. no cAMP means contractility is decrase and vasoCONSTRICTION, no????
    means b-blocker can cause vasoconstriction leads to increase BP
    please correct me if i misunderstood

  • @monika246
    @monika246 4 ปีที่แล้ว +1

    Wowwww...just loved it

  • @anahmoon522
    @anahmoon522 2 ปีที่แล้ว

    I laughed when you said "it's common sense" 🤣

  • @a30694
    @a30694 3 ปีที่แล้ว +1

    cAMP acts on smooth muscle of blood vessels and cause vasodilation and a decrease in bp. On the other hand it increase angiotensin ii and aldosterone and causes vasoconstriction and salt and water retention and increase bp. So which is the predominant effect?
    Please help me out.

    • @tylerwilliams6882
      @tylerwilliams6882 3 ปีที่แล้ว

      did you find an answer to this? I'm wondering the same thing

  • @doctorgvlog
    @doctorgvlog ปีที่แล้ว +1

    Lovely sir

  • @muhammaduwais5323
    @muhammaduwais5323 4 ปีที่แล้ว +2

    Really helpful

  • @danagreenberg945
    @danagreenberg945 3 ปีที่แล้ว

    this was perfect

  • @ضحىيوسف-ع2ت
    @ضحىيوسف-ع2ت 4 ปีที่แล้ว

    Thank u for this video and please teach us the biochemistry

  • @JoyceGem
    @JoyceGem 3 ปีที่แล้ว +1

    HAHAHAHA your wit tho 🤣🤣 tbh this is the way I study too. Lmao "this is common sense" HAHAHA

  • @Dr_fonesz
    @Dr_fonesz 4 ปีที่แล้ว

    Very informative.

  • @banjitkalita8556
    @banjitkalita8556 3 ปีที่แล้ว

    How cAMP contract heart muscle and dilate smooth muscle??

  • @georgep.7492
    @georgep.7492 4 ปีที่แล้ว

    I am not even studying pharmacology this year, but this was nice

  • @aroor1785
    @aroor1785 2 ปีที่แล้ว

    Is there a place i can get the transcript of this lecture from ? 18 minutes video made me understand so much about antiplatlets therapy, and some of the most common shock hf interventions we take ,, and even aminophyline toxicity .. thank u man

  • @olaabdallah3607
    @olaabdallah3607 ปีที่แล้ว +2

    Amazing video ❤
    Btw love your accent, are you egyptian? 😂

  • @Srun-p2b
    @Srun-p2b 11 หลายเดือนก่อน

    Hello ! Anyone can explain me why a2 receptor -> Gi pathway -> low c AMP, but it cause relaxation?
    (Source: b. α2 Receptors
    are located on sympathetic postganglionic nerve terminals (autoreceptors), platelets, fat cells, and the walls of the GI tract (heteroreceptors).
    often produce inhibition (e.g., relaxation or dilation).
    Mechanism of action: Gi protein, inhibition of adenylate cyclase and
    decrease in cyclic adenosine monophosphate (cAMP). )

  • @ABC-fv7ow
    @ABC-fv7ow 2 ปีที่แล้ว

    Superb 👌

  • @frodobeutlin4368
    @frodobeutlin4368 4 ปีที่แล้ว +1

    you son got a new customer ;)

  • @rathodnehal2869
    @rathodnehal2869 4 ปีที่แล้ว

    can you make video on cGMP mediated vasodilator

  • @sonya1500
    @sonya1500 2 ปีที่แล้ว +1

    I am a simp for medicosis perfectionalis.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว

      Haha 🤣
      Funniest comment ever!

    • @sonya1500
      @sonya1500 2 ปีที่แล้ว

      @@MedicosisPerfectionalis I am dead serious babe

  • @polarispolaris1705
    @polarispolaris1705 ปีที่แล้ว

    شرحك ممتاز

  • @dianalynvillanueva1216
    @dianalynvillanueva1216 3 ปีที่แล้ว

    this is so cool. hahha thanks for yhe good pneumonic 😎

  • @immadisarojini2775
    @immadisarojini2775 3 ปีที่แล้ว

    Super

  • @bealambwouldya
    @bealambwouldya 4 ปีที่แล้ว

    This easier to understand then my teacher 💀

  • @artbylupiv
    @artbylupiv 2 ปีที่แล้ว

    Man you are asm just awsm

  • @juliandionne7209
    @juliandionne7209 2 ปีที่แล้ว

    great

  • @black.beerd.gaming
    @black.beerd.gaming 2 ปีที่แล้ว

    completely savagery, I'll be rewatching this video for fun

  • @lujnas
    @lujnas 2 ปีที่แล้ว

    god, his voice..........

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว

      Good or bad? 🤷‍♂️

    • @lujnas
      @lujnas 2 ปีที่แล้ว

      @@MedicosisPerfectionalis shy to say 🏃🏼‍♀️

  • @elizabethrouse4182
    @elizabethrouse4182 2 ปีที่แล้ว

    you misspelled messenger ;-)

  • @hemanth.sgowda702
    @hemanth.sgowda702 4 ปีที่แล้ว +2

    👏👌

  • @thinkpositive8328
    @thinkpositive8328 2 ปีที่แล้ว

    😎😎

  • @aroor1785
    @aroor1785 2 ปีที่แล้ว +1

    Convert it into trash called degradation products ahhahahhahahahhahahhahhahahhahahahahhahahahahhahahahah

  • @evaneckhart9648
    @evaneckhart9648 2 ปีที่แล้ว

    L accent