7 Ways To Boost Mitochondrial Health To Fight Disease
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- เผยแพร่เมื่อ 16 พ.ค. 2024
- Mitochondrial dysfunction is at the root of many diseases ranging from cancer to diabetes. This video explains how mitochondria are involved in our health, and shows 7 ways to keep our mitochondria healthy to help prevent disease.
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Thanks. To reduce toxin exposure, I switched from carpet to hard wood floors. Previously, when I vacuumed, the vacuum cleaner just filled up way to quickly. Now keeping things clean is much easier.
Simply eating beef can boost your mitochondria as stearic acid from beef and taurine have amazing benefits for mitochondria, but nothing is going to help with your mitochondria more than doing some fasting!
If it is grass fed beef
World full of soon to be dead experts. Google college light undergraduates featuring youtube university students
All cows are fed grass until harvested.
Yes, the cows on feed lots for the last few months of their lives are fed grass. Yes they are fed corn. The corn is that 6’ tall plant that holds the (1) ear of corn. It is harvested as silage.
Calves, baby cows, are not raised on feed lots. They are born on a ranch. They drink milk from their mother. Then after ~ 14 months are sold to a feed lot. They get harvested after ~ 4 months.
One of the byproducts from making apt, energy, by the mitochondria is low deuterium water ...this is easily produced eating animal products ...that's why a diet with meat will always be the healthiest.....high deuterium water is a growth promoter, say hello cancer
Thank you
Hello,respected sir very nice suggestions for Gut health issues with Gallbladder chronic cystitis issues and huge bloating issues
Thank you for Such Great Infos!🙏
Good info!
Oh talking to a primary care doc who prescribed a drug that they didn’t know in the first place would hurt our mitochondria is always a good idea. I n my experience in this life I do not trust very few WM doctors with any chronic illness or disease. Peace
Definitely a contradiction. As the person whose body I alone experience, who better to decide what works and what doesn’t for that body?
Everything you mentioned has great for mitochondria but generic also plays a big role in longevity
Thank you for this great video!
This dovetails right into Dr Thomas Seyfried's research and 150 papers on the metabolic origins and usefulness in the treatment of cancer.
Congratulations on your videos. Are excellent.
Thank you! Much appreciated!
Excellent program on such an important topic as Dr. Kuehne explains this so well. Pithy, succinct with great takeaways. For mitochondria, the type of exercise I have learned from my CPT and Advanced Senior Fitnesss Training was Zone 2 cardio. Resistance training is critical as well and for the myokines and helping with metabolic health. Would love for you to explore exercise and its effect on health markers. Thank you - will pass on.
Thank you. I think that’s an excellent idea.
This was very well put together! Thank you for the information
Thank you for your kind words. Much appreciated.
Interesting information. From my personal experience i agree with your take on autophagy, even because e can combine exercise and fasting in a way to trigger autophagy.
Thank you for your feedback. Yes, the benefits of autophagy, mitophagy, and improved insulin resistance can be seen with regular intermittent fasting and even modest 14 to 18 hour fasting windows. I find this very encouraging and motivating to someone with impaired glucose tolerance or early diabetes.
Very clear and helpful, thank you very much!
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Great narrative! Subbed!
Thank you!
Such great info.
Thanks for watching!
@@JonasKuehneMD Can you post the references that demonstrate seed oils being unhealthy? Recent studies, not something done 50 years ago. What I see is study after study showing that either inflamation is reduced or not affected at all with increased seed oil consumption and also a link to less heart disease and cardiac events. So what is the basis for the claim that these oils are unhealthy?
@@JonasKuehneMD could you do video on ivermectin as used for cancer? And even aspirin...
@@cyberfunk3793The trials you want will never be held. Who will pay?
Excellent info - PQQ is also good for mitochondrial health
Yes, great point! I was going to do a video specifically about PQQ as many people do not know about this molecule.
I take Coq10 with PQQ. It's 85$ a month. But worth it.
What is Pqq ?
I hate that sunflower oil is in too many things.
Hi doc, I loved this info. and have subbed you. I'd like to let you know that i'm CMV positive and unable to gain weight.
Could you please make a video on this virus which not many people are aware about yet majority of population harbour this virus in them that may produce complications in later life.
What type of diet you would recommend to healthy sedentary adults who are CMV +ve and want to gain healthy weight and keep the virus latent as long as possible?
Thank you for your feedback. That sounds like a very important topic and I will definitely look into it. Are you currently taking methylene blue? It can greatly improve mitochondrial health and is also acting as an antiviral. Maybe a topic you could discuss with your primary care doctor.
@@JonasKuehneMD Thank you so much for your response. Cannot wait for your next video on this topic.
And, surely i'll consult with my doctor on MB.
Very balanced video. However can we measure the health of the mitochondria just like we test many organs or lipids. I already do all the things you have mentioned and my blood results are all very well especially BMI, tg/hdl of 0.5, CRP 0.3, vo2 max at 60, grip strength, etc…
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Unlimited appreciation for the inclusive and yet simple presention of this integral topic which greatly added to my search of the components of preventing and treating ailments.
I was diagnosed with stage 4 breast carcinoma and been in search of knowledge.
How can i reach u personally Dr. Kuehne ??
Thank you for your kind words. You can send me an email to frontdesk@cryohealthcare.com. Please address to Dr. Kuehne.
Yet another youtube university student
There seems to be a trade off between longevity & cancer prevention vs muscle growth.
Can you talk about how to optimize/ balance both?
TYIA!
I think that health, longevity, and muscle growth can go hand-in-hand. A low carb high protein diet, optimizing body fat can achieve these goals. I will do a more detailed video on this at some point.
@@JonasKuehneMD Okay, good to know! Looking forward to the video!
Hi, Jonas, dont you worry about the phtalates and plasticisers uses in softgel pills like omega 3 and vitamin D3 ??
I wait for your answer😊😊
Great video. Just a few comments, from my experience suffering from cronic fatigue due to Ross River fever. Viruses also damage mitochondria. I did take the supplements of CoQ10, l-carnitine, ala, etc, but they only helped so much. The best thing I did was intermittent fasting.Twice a month for four or five months, anywhere between 36 to 48 hours. I could see the results within 3 days of fasting each time. I don't need to fast anymore. I'm very healthy. I'm 57 and I don't take any prescription medication. If any of my symptoms come back, the only thing I will do is intermittent fasting. Of course I always eat healthy too.
That’s great advice, and I agree that viruses can certainly damage mitochondria. Have you looked into methylene blue? My video on this topic will come out tomorrow. Methylene blue can greatly improve mitochondrial health and is also an anti-microbial agent.
I suffer with chronic fatigue, but I cannot fast 😂😂 I have tried and tried and it’s just so so hard. I know fasting is the best thing one can do to improve general health, but this eating little and often, it’s worked years ago, not it’s a habit that’s hard to shift.
@@aluna_m888 Try doing 12 hours only at first. Then increase to 16 hours, and so on. The body will adjust over time. For example, every Saturday, fast for12 hours. After one month, fast for 16 hours. You only have to do one 36 hour fast per month to see the results. This is the only way nature has designed our body to recycle and heal itself. The power to fast is in your mind.
@@JonasKuehneMDThanks so much for this video. I'm suffering from long Covid since 2020 followed by vaccine injury.
I'm finding B1 benfotiemne at 900mg a day extremely helped cognitive impairments ( brain fog)
This was very noticeable within a few days... Theory being it's helping mitocondria process gulcoses 🤷🏼♂️
I started on methylene blue yesterday also 👍🏼
@@Ezpize626
May I ask what brand of methylene blue you've purchased? I want to try it in hopes it'll help with my chronic fatigue.
I also hope you'll report back shortly on your dosing and results. Best of luck. TIA
I Totally agree and i tried to tell the Oncologist that was treating my dads cancer. I say because Otto Warburg effect
The Warburg Effect causes alterations in mitochondrial redox potential, ultimately changing ROS generation [18]. An important determinant of redox potential in cells is the NADH that is available in the mitochondria for electron transport.Jan 5, 2016
The Warburg Effect: How Does it Benefit Cancer Cells? - PMC - NCBI
Also the other important aspect is the Proton Pump Health.
Lastly what are the best way to test the Mitochondria ?
You can test your mitochondrial DNA, however, testing the general metabolic health of mitochondria is difficult.
@@JonasKuehneMD like testing the MPK or the Proton Pump as 2 examples. what is difficult is sometimes just as important as easy test
Subbed, doc!
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Nice summary. Perfect for sharing. Finding the right balance when post menopausal is hard. Aiming for prevention of mitochondrial damage rather than weight loss may be more motivational when you feel like an alien has taken over your body. I’m going to try that. Thank you.
I agree... excellent summary of recent research highlights in layman's terms, perfectvfor sharing.
Best advice: No alcohol, no smoking,no sugar, no pork……..
I've read that using a sauna (dry not steam)is beneficial to your mitochondria. Could you comment on what temperature would be too high for someone with lupus?
Yes, a regular sauna through heat stress can increase mitochondrial function. an infrared sauna that has near infrared as part of its wavelength spectrum can also directly stimulate mitochondrial health and function.
Auto immune disorders like lupus increase inflammation. I am not sure whether or not that can be an issue. Cold therapy in the form of whole body cryotherapy has been shown to be extremely anti-inflammatory for autoimmune disorders.
th-cam.com/video/btl1y9rMVbY/w-d-xo.htmlsi=cNJAvviZSuijEcGh talks about biohack that can get inside an inflamed cell.
Seasonal diet makes the most sense from an evolutionary perspective. The shock from switching also helps the microbiota.
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Time stamps would have been useful 😊🙏👍
You said, “Sh1tty!” 😂😂 I love it!
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Thank you Dr Kuehne for spreading the word for what has been coined as the metabolic approach. This approach has been extolled by Dr Thomas Seyfried (if the reader is unfamiliar with his work a search on TH-cam will unearth many entertaining interviews with this gentleman) and before him the winner of the 1931 Nobel Prize in Physiology, Otto Warburg.
Well said!
I shall look this information up.. many thanks 🙏🏼
I just discovered that i have Hashimoto's. Already gone Paleo and taking numerous supplements. For mitochondria I take Ubiquinol, PQQ, creatine, NAC and magnesium citrate (speeds peristalsis). I also have a small near-infrared panel although I'm hoping to get a more modern one with a broader spectrum. My recovery from exercise is already improving so I know that it is working.
Yes, dietary changes are very important here. I would strongly recommend to cut out all gluten, which is easily achievable on a Paleo diet. I did a video about gluten a few days ago, and the research was fascinating. None of us can digest gluten completely, and it triggers an immune response with hydrates inflammation in the small intestine in everyone. For some people, this is very mild and goes unnoticed more profound with symptoms. This inflammation increases zonulin causing a widening of tight, junctions in the small intestine and a leaky gut. This allows antibodies and gluten particles to enter the bloodstream and contributes to auto immune disorders like Hashimoto’s thyroiditis.
Oh wow this is very interesting, I've developed autoimmune after " preventive medication" I'll need to look into gluten free @@JonasKuehneMD
❤ from INDIA......Thanks.
Thoughts on methylene blue
It’s a great antibacterial/antiviral medication, and can also improve mitochondrial health by directly impacting the electron transport chain. Also has antioxidant and anti-inflammatory properties.
@@JonasKuehneMD awesome thank you so much great video!
Very much appreciating the quality of your video. At 6:21 you mention the link between obesity and cancer.
I am just perplexed by something. Wouldn’t it be relatively easy to simply measure categories of body fat composition against cancer rates? Body fat is super easy to check. Cancer is not exactly but close to binary (you have a malignancy or not).
Then…. At different ages, different types of cancer, etc you just determine: is there a large statistical difference between, let’s say,
Great question. They have been a lot of studies to prove the relationship between obesity and cancer. They even describe the percent increase.
www.hindawi.com/journals/isrn/2013/680536/
nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1749-6632.2012.06750.x
I have seen youtube videos claiming that aspirin has shown some benefit fighting some forms of cancer. Any clue to the risk to benefit ratio of taking microdoses of aspirin?
Some studies have shown that low-dose aspirin may decrease the risk of colon cancer. The recommendations for aspirin are always varying in the medical community. There is, of course, the risk of poor blood clotting and GI issues like ulcers.
Thank you Dr. Brad Pitt!
Haha, thank you, but you owe Brad Pitt an apology. Unless we are talking about the first 30 minutes of Benjamin Button… 😂
I have yet to encounter a PC Dr. who is interested in or knowledgeable about nutrition.
You are sadly correct. I am hoping that this will change.
I'm guessing this has been asked but what about peanut oil like in natural peanut butter (no other ingredients)? Is this bad for us as well?
I eat peanut butter occasionally. If it is the only ingredient other than salt and it is from organic peanuts, I see no problems with it. It does have a higher percentage of omega six linoleic acid, but it is still a good fat in my opinion.
@@JonasKuehneMD Thanks for the quick response!
Why recommend keto only short-term, or as needed (for example, cancer)? After 2 years in nonstop ketosis, I have NO desire to return to the foods that were making me sick.
Some people do great on keto, long-term, others may have issues to get sufficient amount of certain nutrients. Also, hormone production can be influenced by a ketogenic diet. I am a big proponent of the ketogenic diet, and believe that the optimal length on the diet can vary individually.
@@JonasKuehneMDwhat are the missing nutrients?
@@aadi6599 Yes Dr Mindy Pelz offers excellent information about all of this, especially for woman as hormones are a massive thing. I have learnt an awful lot from her.
Total BS. You have NOT been in ketosis for 2 years.
@@napua5217electrolytes. Most carnivores take an electrolyte supplement.
Any info on the supplement l-carnitine?
I have not done a video on L-carnitine yet.
Thank you. I was just wondering if l carnitine can improve mitochondrial health can it be part of a supplement arsenal for melanoma cancer?
Yeah, I like statins about as much as I like amphetamines. Not not not. This is an exceptional lecture. My second listen. Keep more coming
Thank you for your kind words. Will do!
So you are saying that eating a ketogenic diet is great if you have cancer and it will help a person heal from that disease? So what diet do you recommend after healing one’s self after healing cancer after eating a keto diet? Are you leaning to go back to eat a high carb diet that got us sick in the first place? Please explain what you mean? Peace
A person being treated for cancer or recovering from cancer should continue on a ketogenic or at least very low-carb diet. In my opinion. It is always important to check with their oncologist or primary care doctor to ensure that levels of minerals and other labs are within range. They should also continue with supplements to decrease the uptake of glutamine, like EGCG, and berberine.
If we could just stop them useless wasting from cancer tho. It's beyond horrible
Muscle wasting *
What can be done for glutamine production?
I am not aware that we can significantly influence glutamine production, but we can decrease glutamine uptake via supplements like EGCG or intermittently block with medications like DON.
Mitochondria love carbon60 affect.
Your information is ok BUT incomplete. You have left off light, sunlight to be exact, and the importance of circadian rhythm. Please check out Dr. Jack Kruse’s work. Light, water (building exclusion zone water) and magnetism these come first THEN comes food and exercise.
I used red/NIR LED panel for 20 minutes on the naked body before daily morning shower.
It goes through clothes
There’s some speculation that red light therapy might be bad, I’d be cautious
It’s fine naturally from the sun but recreation of it may not be all it’s cracked up to be and may actually lead to unfavorable outcomes
@@napua5217
Are you sure about that, Son?
@@ianstuart5660 ? What do you want?
I need a non synthetic vitamin b complex or B1. Anybody???
Thorne Basic Nutrients 2/Day -
I did not buy Thorne!!! Here’s why: Pyridoxine form of B6 is toxic and should be changed to all P5P or pyridoxal
Reviewed in the United States on June 27, 2018
Size: 60 Count (Pack of 1)
I used to think this was one of the best B complex. Unfortunately, new research (The vitamin B6 paradox on researchgate (full study free) from 10/2017 is indicating that the pyridoxine form of B6 INHIBITS the active B6 form P5P so it is actually working against you when you supplement pyridoxine (not P5P) and working instead toward making you more deficient instead in B6 as you take more pyridoxine. It also
was found to significantly increase cell death the more you take in SHSY5Y cells, even in lower doses as well. It is the toxic form. It mentions that Lareb reported cases in which even lower doses (2 mg/day) of vitamin B6 in pyridoxine form gave the same complaints of neuropathy as high doses. So while this is new information that Thorne may not know about yet, it seems that its best to avoid pyridoxine and use only P5P form for B6 and might want to check your other vitamins for the ingredient. According to the european food safety authority, the tolerable upper intake levels for vitamin b6 pyridoxine is 25mg per day and this was before any of this information, and this product contains the maximum but is typically in many other products you may use. Hopefully they will reformulate it and I will certainly consider repurchase and changing the rating if they do, as it was great otherwise. The thorne basic b complex has P5P but has a super high dose of Thiamin and Niacin that some may have issues with so I have generally used Douglas Laboratories B Complex with Metafolin, or occasionally Seeking Health B Minus when I dont need the B12/Folate.
Also a good company would never sell synthetic vitamins right?
Non fortified nutritional yeast?
And all the while, we have a Medical community that ignores this proven we think, way of avoiding the poison given that is known to kill you!
But most human food is carbohydrates, maize, rice, wheat, barley, oats, etc so how can we avoid carbohydrates???
You do not have to avoid carbohydrates, but I recommend to reduce simple sugars, and keep carbohydrate intake, moderate. Especially if your last meal of the day does not contain carbohydrates, you will go into a state of ketosis faster overnight.
@@JonasKuehneMD ,but ketosis also has its downsides, why not just increase the amount of exercise you do to burn off carbohydrates you consume, because consuming carbohydrates is natural fuel for the body????
@georgehosea139 fat is a more natural fuel for the body! You don't need to ingest carbohydrates to exercise, your body can run off body fat stores and can make it's own glycogen for higher intensity exercise.
We can take alpha lipoic acid to recycle coq10?
From “ask the scientists”:
Skeletal muscle function largely depend on intact energy metabolism, stress response, and antioxidant defense mechanisms. CoEnzyme Q10 (CoQ10) has an essential function in the electron transport chain in the inner mitochondrial membrane, and is involved with cellular respiration and mitochondrial biogenesis. It is also known as an important antioxidant. Alpha-lipoic acid is synthesized in the mitochondria and plays a role in mitochondrial function. Alpha-lipoic acid and CoQ10 do not likely work in isolation, but synergistic activity of CoQ10 and ALA in muscle fibers are not well documented.
Check out Dr. Jack Kruse, Dr Zack Bush, Dr Ronda Patrick, Dr Ted Archaco, Dr Dom D AUGOSTINO. ❤
Thank you. I will.
Avoid quaternary ammonium compounds for mitochondria wellness!
Programmed cell death is apoptosis, not autophagy
That is correct; i’m not sure where I mentioned a ptosis. My goal was to talk about autophagy and mitophagy from intermittent fasting.
Actually, there is work being done on long-term ketosis, and even carnivore! And it looks like all the warnings were just wrong or made up! Standby for published papers!
Yes! Every Human being is born IN KETOSIS.
Humans definitely do well longterm ketosis. Just look at us. With out it humans would not exist. Anyone that thinks longterm ketosis is anything other than natural state of human 🤔 🙄 they don't know how to think.
I followed a ketogenic diet for over two years and did great on it. There were a few drawbacks in terms of minerals and nutrients that I should have addressed differently in retrospect. I think some people can definitely thrive on this for long periods of time, while for others it could be a short-term start into a better metabolic state.
@@JonasKuehneMDcan you explain which mineral and nutrients are missing on a keto or carnivore diet?
@@napua5217dr sten ekberg has a good video on it 🎉
Sugar is the HAVEN on earth.
Chocolate ❤❤❤
Yes you are right sugar feeds bacteria just eat a lot of sweets to see how happy the bugs feed in your mouth leaving their scum on your teeth, it's the same throughout you body all disease feeds on sugar. For better health reduce sugar intake.
Use allulose instead of sugar.
Any thoughts on methylene blue as a supplement for mitochondria health?
@@dougphillips5686
Where do you get it?
my Humble request to hare some more raw fruits for better Gut health issues and fatty liver issues suffering from huge under weight issues
7:30. Phew he didn't say weed.
I am not sure about the building of muscle. The more muscle you have puts more of a burden on the system.
That is true to some extent. Excessive muscle tissue is limited by the body via myostatin. Most people face the issue of decreased muscle mass mass as the age. Therefore building sufficient muscle is helpful for a healthy metabolism and lower body fat.
@@JonasKuehneMD But is musle an indication of good health or the producer of it. Just as my G wagon is an indication of wealth not a producer of it. If regular folk get one they would end up much poorer as a result..
Cancer is fungus. Watch Dave Asprey's interview with Mark Lintern...you can thank me later 😉
have you heard of a man called Ray Peat?
I have not, but will do some research. Thank you.
@@JonasKuehneMD he has written many articles about the mitochondria, specifically its interactions with unsaturated and saturated fats
Dr Sara Pugh is much more informed than he