Some red light proponents suggest that red and near-infrared light can reduce skin damage caused by ultraviolet light (UVB). If a primary manifestation of UVB damage is damage to mitochondria, that supports the red light proposal since red/NIR light can boost mitochondrial energy production and hence health. Seems like the takeaway is to further suggest doing everything you can to keep your mitochondria healthy. Maybe that includes consuming senolytics.
People already suffer for lack of vitamin D with tremenduos consequences on their immune system and overall health. I love my sunshine vitamin and it benefit on various metabolic aspects. Will not trade sunshine for less wrinkless.
Keeping senescent cells alive considering it's a result of telomere shortening is a bad idea since cells with short telomeres are more likely to have chromosome fusion and thus become malignant.
Inducing aging by UVB and then rejuvenating, will not show you what happens in vivo. Reason: You're not taking into account the effect of 50 or more years of metabolism on the skins condition. (Filling up of lysosomes, Glucosepane and other cross-linkers. Et al.)
to get rid of senescence cells, most of the drugs are from repurposed cancer drugs and need prescription. over-the-counter drugs w/o prescription they are everywhere but they are not very good.
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Some red light proponents suggest that red and near-infrared light can reduce skin damage caused by ultraviolet light (UVB). If a primary manifestation of UVB damage is damage to mitochondria, that supports the red light proposal since red/NIR light can boost mitochondrial energy production and hence health. Seems like the takeaway is to further suggest doing everything you can to keep your mitochondria healthy. Maybe that includes consuming senolytics.
People already suffer for lack of vitamin D with tremenduos consequences on their immune system and overall health.
I love my sunshine vitamin and it benefit on various metabolic aspects.
Will not trade sunshine for less wrinkless.
Keeping senescent cells alive considering it's a result of telomere shortening is a bad idea since cells with short telomeres are more likely to have chromosome fusion and thus become malignant.
They are talking about elimination and senolitics. Keeping?
Inducing aging by UVB and then rejuvenating, will not show you what happens in vivo. Reason: You're not taking into account the effect of 50 or more years of metabolism on the skins condition. (Filling up of lysosomes, Glucosepane and other cross-linkers. Et al.)
I have experiance in senolytic treatment with Dasatinib and Quercetin. It works amazing.
not buying the open window thing..
Is there anything actionable in this?
Sun protection, regular autophagy
Improve your diet aimed at mitochondrial support. Build a lab to test yourself. Adjust accordingly. 🎉
@@jorgesmith911 How to increase authophagy in skin? (intense exercise works in general)
@@zandiskoul thanks, oily fish apparently
@@eddyoo this makes no sense: isolation is correlated with lower life expectancies, and none of the king lived areas are vegan
Surprising that old skin has 10 percent senescent cells
My left face aged quicker as my working desk is next to the window:-(.
Thank you!
Does taking quercetin help?
It helps regulate protein production quality control, so to some extent, yes.
Apparently yes 😊
to get rid of senescence cells, most of the drugs are from repurposed cancer drugs and need prescription. over-the-counter drugs w/o prescription they are everywhere but they are not very good.
This video has a list of effective drugs to use. WALS Lecture: Laura Niedernhofer Ph.D
Do you have a link?
All these exclamation marks are just silly.
Wow!!... :)