How to calculate inbreeding from a pedigree chart

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  • เผยแพร่เมื่อ 5 ต.ค. 2015
  • Though there are computer programs, which will calculate the inbreeding coefficient automatically, based on pedigrees entered into a database, it is still handy to be able to calculate the inbreeding in less complicated pedigrees manually. Here is a short description on how to calculate the inbreeding coefficient from a pedigree by using the path coefficient method.

ความคิดเห็น • 119

  • @theyellowsparks
    @theyellowsparks 5 ปีที่แล้ว +8

    Thanks so much for this! My actual textbook doesn't seem to do a good job of showing examples... I needed help on the third example and you nailed it! Thanks!

  • @LauraMaria-yj9lt
    @LauraMaria-yj9lt 5 ปีที่แล้ว +1

    I´m very happy about finding your channel! You have helped me a lot already. Enjoy your day, thank you.

  • @fortunatembongo7200
    @fortunatembongo7200 4 ปีที่แล้ว +3

    Thank you so much, I never thought I would understand this in 15 Minutes.

  • @ThiagoBenazziMaia
    @ThiagoBenazziMaia 3 ปีที่แล้ว +3

    Thank you, 4 book pages of my book and I didnt understand. I watched 3 minutes of your video and now I got it. Thank you

  • @AquaDonAdventures
    @AquaDonAdventures 8 ปีที่แล้ว +7

    Thank you very much for your explanation. It was clear and easy to understand :-D

  • @moniabenadda9995
    @moniabenadda9995 7 ปีที่แล้ว +14

    Thank you so much u cant believe how much this helped me preparing for my finals ❤️❤️

    • @GeneticsLessons
      @GeneticsLessons  7 ปีที่แล้ว +2

      You are welcome! Thanks for watching.

    • @moniabenadda9995
      @moniabenadda9995 7 ปีที่แล้ว +1

      Nikolay's Genetics Lessons thank you

  • @hania.1220
    @hania.1220 2 ปีที่แล้ว

    You are my saviour!!thank you so much. You explained it clearly and easily⚘

  • @snigdhabanerjee5395
    @snigdhabanerjee5395 5 ปีที่แล้ว

    Thank you so much sir...ur all videos on imbreeding helped me a lot sir....

  • @suberuhamzaho546
    @suberuhamzaho546 2 ปีที่แล้ว

    Thank you for this explanation! You sure are gna making me pass my finals👍🏾

  • @mhackbardt
    @mhackbardt 7 ปีที่แล้ว +2

    Getting ready for the genetic counseling boards. thank you.

  • @anushkaathukorala_vonserendib
    @anushkaathukorala_vonserendib 7 หลายเดือนก่อน

    One of the best videos. Explained very well and easy to understand it. Thanks a lot.

    • @GeneticsLessons
      @GeneticsLessons  7 หลายเดือนก่อน +1

      I have many more videos on this topic with more complex examples.

    • @anushkaathukorala_vonserendib
      @anushkaathukorala_vonserendib 7 หลายเดือนก่อน

      Yes I will watch but as someone who do not have scientific background it takes me sometime to understand it but I am really interested in COI. Can you please tell me do you explain " Weight's or Hardiman's COI?

    • @anushkaathukorala_vonserendib
      @anushkaathukorala_vonserendib 7 หลายเดือนก่อน

      I am Breeding dogs and I see COI in the dogs pedigrees and that is why I want to learn about it. 😊 By the way in the second example should the answer be 1/64? Or am I wrong?

  • @user-mm6ql9bz6s
    @user-mm6ql9bz6s 7 หลายเดือนก่อน

    Thank you for your explanation. I'm able to solve my exercise related to pedigree analysis

  • @anushkaathukorala_vonserendib
    @anushkaathukorala_vonserendib 7 หลายเดือนก่อน

    This video is very useful to me as a breeder because I see COI in dogs pedigrees. ❤

    • @GeneticsLessons
      @GeneticsLessons  7 หลายเดือนก่อน

      Do you know that I have a playlist - dog's breeding? Check it out.

  • @samrawitgebeyehu7648
    @samrawitgebeyehu7648 ปีที่แล้ว

    Thank you so much! Very clear description!!!

  • @erickaoctaviora696
    @erickaoctaviora696 5 ปีที่แล้ว +1

    Thank you so much! Its helped me a lot.

  • @nageshgorsera8569
    @nageshgorsera8569 10 วันที่ผ่านมา

    thank you so much. it was easy to understand and after a bit of practice it was fast .

  • @swethaeswathe6144
    @swethaeswathe6144 ปีที่แล้ว +1

    Easily understood sir. . thank you sir 🙏keep doing..

  • @tabbutabbu7075
    @tabbutabbu7075 5 ปีที่แล้ว

    Thanku very much sir....
    Very easy trick to solve the problems....

  • @ewanentiege8931
    @ewanentiege8931 3 ปีที่แล้ว

    Thanks very much. Well explained n simplified

  • @sashikantaparida9763
    @sashikantaparida9763 6 ปีที่แล้ว +3

    Thank you sir.

  • @fanifariedah
    @fanifariedah 6 ปีที่แล้ว +1

    its easy to understand... thank you

  • @russell1841
    @russell1841 3 ปีที่แล้ว

    This is amazing. Thanks!

  • @fathimanajla5913
    @fathimanajla5913 ปีที่แล้ว

    Thank you
    Clear Explanation🙌

  • @karinkburns
    @karinkburns 7 ปีที่แล้ว +1

    Thank you. Ochin intereshna.

    • @GeneticsLessons
      @GeneticsLessons  7 ปีที่แล้ว

      You are welcome! Thanks for watching.

  • @roro3793
    @roro3793 5 ปีที่แล้ว +2

    Thank you for your video I really enjoy learning about genetics. I have a question. Say I wanted to systematically check every individual recessive allele in an individual mouse. It's my understanding that you could use line breeding to increase the inbreeding coefficient. So breeding daughter back to father after 5 or more generations should bring you close to 100% coefficient. And at that point majority of the genes would be homozygous.
    Now say instead I made a cross between two unrelated mice. And then I took 5 daughters from that one pairing and bred them all back to the father. In theory the majority (near 100%) of the fathers alleles would be represented as homozygous across all grandchildren children but the inbreeding coefficient of each individual would only be 25%. Is this correct?

    • @GeneticsLessons
      @GeneticsLessons  5 ปีที่แล้ว

      These videos might help you:
      Simple Inbreeding Problem and Solution th-cam.com/video/WK-IVGvvDUU/w-d-xo.html
      How to Find Inbreeding Coefficient (advanced problem) th-cam.com/video/BH07HbEkx6s/w-d-xo.html

  • @esoheiyare9874
    @esoheiyare9874 8 ปีที่แล้ว +1

    Thank you very much

  • @Light_prevails
    @Light_prevails 3 ปีที่แล้ว

    Thank you so much
    I finally understand this

  • @arias.p4355
    @arias.p4355 3 ปีที่แล้ว

    Thank you very much...it was helpful 💖

  • @CHEH_tf
    @CHEH_tf 2 ปีที่แล้ว

    thx bro that's really useful

  • @NourBellil-mb1hp
    @NourBellil-mb1hp 2 หลายเดือนก่อน

    Thank you so much !

    • @GeneticsLessons
      @GeneticsLessons  2 หลายเดือนก่อน

      Today, I am starting a new series of short videos debunking the 'Out of India' theory.
      th-cam.com/users/shortsnv3YrBrGXdU

  • @JB-01
    @JB-01 ปีที่แล้ว

    Thank you so much❤

  • @saadisabrina2527
    @saadisabrina2527 2 ปีที่แล้ว

    thanks so much really interessting

  • @Shagunagarwal.
    @Shagunagarwal. 3 ปีที่แล้ว

    Mannn u r the best

  • @bibliothekdeshorrors4084
    @bibliothekdeshorrors4084 3 ปีที่แล้ว

    Great explanation. But I have a question. What if the common ancestor appears multiple times in the pedigree? For example:
    A appears on the fathers as the great grandfather but on mother's side as the father AND grea great grandfather. How would I count that? As one sire appears three times in a pedigree?
    Do I only take the closest one to the mother so the father?

    • @GeneticsLessons
      @GeneticsLessons  3 ปีที่แล้ว

      I have many more examples of inbreeding - just search my channel.

  • @allblackeverything405
    @allblackeverything405 2 ปีที่แล้ว

    Thank you so much

  • @adityakhanijo7433
    @adityakhanijo7433 3 ปีที่แล้ว

    Amazing!

  • @anthonylewis7812
    @anthonylewis7812 2 ปีที่แล้ว

    thank you so much

  • @sheikhseerat7105
    @sheikhseerat7105 5 ปีที่แล้ว

    Helpful

  • @bonimaxwadenmark1
    @bonimaxwadenmark1 5 ปีที่แล้ว

    Am learning here

  • @imaspinner76
    @imaspinner76 ปีที่แล้ว

    I realize this video is 7 years old. BUT I can't find the answer to my question. Though I haven't watched every coefficiency video you have. I breed goats and I am just learning coefficiency in breeding. Thank you by the way for making these videos!
    I have a diagram I'd love for you to look at. But no way to send it to you.

    • @GeneticsLessons
      @GeneticsLessons  ปีที่แล้ว

      I have many more examples of inbreeding - which covers basically 90% of all cases. Please check the folder "inbreeding".
      You may send me a link to google doc - or write to my email which you can find in "about this channel".

  • @GeneticsLessons
    @GeneticsLessons  4 ปีที่แล้ว

    Watch my new video:
    "Inbreeding and Loss of heterozygosity explained" th-cam.com/video/5NYEJ1XbhQ4/w-d-xo.html

  • @walaaesseid9348
    @walaaesseid9348 2 ปีที่แล้ว

    thank u

  • @reemaxx2080
    @reemaxx2080 6 ปีที่แล้ว

    What does it mean when the numbers are bigger or lower? I mean in your example baby no2 is 1/32 and baby no3 is 1/16 . Dose it mean that baby no3 is inherting more from thier parents and ancestors ?
    Dose it have anything to do with passing and pushing harmful genetics?

    • @GeneticsLessons
      @GeneticsLessons  6 ปีที่แล้ว +1

      The bigger the number the bigger probability to inherit SAME allele . Say probability 1/16 is bigger than 1/32.

    • @alokneet
      @alokneet 5 ปีที่แล้ว

      @@GeneticsLessons Nicolay

  • @XXTheDonkey
    @XXTheDonkey 5 ปีที่แล้ว

    I have a hw problem that starts with 2 separate lineages that eventually come together...and im very confused

    • @GeneticsLessons
      @GeneticsLessons  5 ปีที่แล้ว

      Check my playlists - I have tens of videos on this topic.

  • @nasserbenomar
    @nasserbenomar ปีที่แล้ว

    MAN ! ! thank you so much .. but sometimes its 1/2 and sometimes solid 1 .. so what the differences ? because this part a bit not clear

    • @GeneticsLessons
      @GeneticsLessons  ปีที่แล้ว

      I have about 100 videos on this topic - just watch more videos and you will understand how it works.

  • @GeneticsLessons
    @GeneticsLessons  5 ปีที่แล้ว

    Watch my new video:
    Adolf Hitler: Genetics vs Eugenics th-cam.com/video/D7cFfS3KfY0/w-d-xo.html

  • @pastat40
    @pastat40 7 ปีที่แล้ว

    What if some individual already was inbreeded? For example, what if individuals C and A in your third case were inbreeded. Lets say C had 0,5 and A had 0,25. What then?

    • @GeneticsLessons
      @GeneticsLessons  7 ปีที่แล้ว

      Than it would be reflected on inbreeding coefficient you have to multiply by this inbreeding numbers.

  • @user-cz3bf6cb4c
    @user-cz3bf6cb4c 3 ปีที่แล้ว

    is this wright or handimans method?

    • @GeneticsLessons
      @GeneticsLessons  9 หลายเดือนก่อน

      Watch my new video: How closely Adolf Hitler's Parents we related? th-cam.com/users/shorts8kajiIuUwxw

  • @GeneticsLessons
    @GeneticsLessons  3 ปีที่แล้ว

    New video: Pedigree vs. Arrow diagram (path analysis) th-cam.com/video/4HeLMpQra7Y/w-d-xo.html

  • @sarahbelaid2897
    @sarahbelaid2897 หลายเดือนก่อน

    please in our lessons they did the same like you did but for exemple they did (1/2)6 but thery multiplie the result to 4 they said because they are 4 possibilities and i didnt understand when we mutuplie the inbreeding to a number in which case and how

    • @GeneticsLessons
      @GeneticsLessons  หลายเดือนก่อน

      Just watch my other videos in "inbreeding" playlist.

    • @sarahbelaid2897
      @sarahbelaid2897 26 วันที่ผ่านมา

      ​@@GeneticsLessons which video please

    • @GeneticsLessons
      @GeneticsLessons  23 วันที่ผ่านมา

      I have many -any which have "inbreeding" in their name.

  • @arisgolseen2693
    @arisgolseen2693 4 ปีที่แล้ว

    What does it mean if "No common ancestry was found in 5 generations"?

    • @GeneticsLessons
      @GeneticsLessons  4 ปีที่แล้ว

      Same ancestor from both mother and father side.

  • @luizfilipepaiva2777
    @luizfilipepaiva2777 ปีที่แล้ว

    Can i use that to calculate inbreeding in humans..?

  • @pseudopetrus
    @pseudopetrus ปีที่แล้ว

    Now I know how I can marry my chickens!

  • @elijahavante2127
    @elijahavante2127 5 ปีที่แล้ว

    If offspring “I” produce offspring Male (M) and Female (F) and inbred produces offspring (O). What will be the inbreeding Coefficient of (O). Thank you awesome videos. Subscribing for more

    • @GeneticsLessons
      @GeneticsLessons  8 หลายเดือนก่อน

      Watch my new video - How to live much longer: th-cam.com/video/nW4ma5Y5liE/w-d-xo.html

  • @dauren.00
    @dauren.00 2 ปีที่แล้ว

    Русский боженька, спасибо что вы это объяснили

    • @GeneticsLessons
      @GeneticsLessons  2 ปีที่แล้ว

      Пожалуйста. У меня еще есть много видео на эту тему с более сложными примерами.

  • @Yue_Jin
    @Yue_Jin 6 ปีที่แล้ว

    explaining how u get the 1/8 or 1/32 would be of great help.

    • @GeneticsLessons
      @GeneticsLessons  6 ปีที่แล้ว +1

      This is exactly what I do in this video.

    • @GeneticsLessons
      @GeneticsLessons  6 ปีที่แล้ว

      Here is another video on this topic: th-cam.com/video/nePPKuwphn8/w-d-xo.html

  • @KateeAngel
    @KateeAngel 7 ปีที่แล้ว

    Вам нужно работатт над произношением. Сильный русский акцент на английском - это что-то ужасное. По себе знаю) А видео очень информативны!

    • @GeneticsLessons
      @GeneticsLessons  7 ปีที่แล้ว

      Я работаю, у нас в университете полно иностранцев которые говорят с акцентом - и ничего ужасного..

  • @alokneet
    @alokneet 5 ปีที่แล้ว

    Nicolay

  • @pavelgrigorchuk5568
    @pavelgrigorchuk5568 6 ปีที่แล้ว +1

    А почему не на русском??

    • @GeneticsLessons
      @GeneticsLessons  6 ปีที่แล้ว

      Всетаки строительство 2000 церквей за последние 5 лет не прошло даром :-) Плоды не заставили себя долго ждать.

  • @ninalilija7039
    @ninalilija7039 2 ปีที่แล้ว

    how is 1/32 + 1/32 = 1/16??? please help

    • @GeneticsLessons
      @GeneticsLessons  2 ปีที่แล้ว +1

      1/32 +1/32 = 2/32 = 1/16
      same as 1/4+1/4=2/4 = 1/2

  • @alokneet
    @alokneet 5 ปีที่แล้ว

    Nicoli

  • @TonyTorzido
    @TonyTorzido 5 ปีที่แล้ว

    daddy nikolay

    • @omp199
      @omp199 4 ปีที่แล้ว

      If Nikolay was your daddy, and you made a baby with him, what would the coefficient of inbreeding of that baby be?

  • @dankobucanac4809
    @dankobucanac4809 7 ปีที่แล้ว +1

    Hello Nikolay, please check your Gmail inbox...

  • @molekul8085
    @molekul8085 4 ปีที่แล้ว

    your accent is so hard