Thanks so much for this! My actual textbook doesn't seem to do a good job of showing examples... I needed help on the third example and you nailed it! Thanks!
Yes I will watch but as someone who do not have scientific background it takes me sometime to understand it but I am really interested in COI. Can you please tell me do you explain " Weight's or Hardiman's COI?
I am Breeding dogs and I see COI in the dogs pedigrees and that is why I want to learn about it. 😊 By the way in the second example should the answer be 1/64? Or am I wrong?
Thank you for your video I really enjoy learning about genetics. I have a question. Say I wanted to systematically check every individual recessive allele in an individual mouse. It's my understanding that you could use line breeding to increase the inbreeding coefficient. So breeding daughter back to father after 5 or more generations should bring you close to 100% coefficient. And at that point majority of the genes would be homozygous. Now say instead I made a cross between two unrelated mice. And then I took 5 daughters from that one pairing and bred them all back to the father. In theory the majority (near 100%) of the fathers alleles would be represented as homozygous across all grandchildren children but the inbreeding coefficient of each individual would only be 25%. Is this correct?
These videos might help you: Simple Inbreeding Problem and Solution th-cam.com/video/WK-IVGvvDUU/w-d-xo.html How to Find Inbreeding Coefficient (advanced problem) th-cam.com/video/BH07HbEkx6s/w-d-xo.html
Great explanation. But I have a question. What if the common ancestor appears multiple times in the pedigree? For example: A appears on the fathers as the great grandfather but on mother's side as the father AND grea great grandfather. How would I count that? As one sire appears three times in a pedigree? Do I only take the closest one to the mother so the father?
please in our lessons they did the same like you did but for exemple they did (1/2)6 but thery multiplie the result to 4 they said because they are 4 possibilities and i didnt understand when we mutuplie the inbreeding to a number in which case and how
I realize this video is 7 years old. BUT I can't find the answer to my question. Though I haven't watched every coefficiency video you have. I breed goats and I am just learning coefficiency in breeding. Thank you by the way for making these videos! I have a diagram I'd love for you to look at. But no way to send it to you.
I have many more examples of inbreeding - which covers basically 90% of all cases. Please check the folder "inbreeding". You may send me a link to google doc - or write to my email which you can find in "about this channel".
What does it mean when the numbers are bigger or lower? I mean in your example baby no2 is 1/32 and baby no3 is 1/16 . Dose it mean that baby no3 is inherting more from thier parents and ancestors ? Dose it have anything to do with passing and pushing harmful genetics?
What if some individual already was inbreeded? For example, what if individuals C and A in your third case were inbreeded. Lets say C had 0,5 and A had 0,25. What then?
If offspring “I” produce offspring Male (M) and Female (F) and inbred produces offspring (O). What will be the inbreeding Coefficient of (O). Thank you awesome videos. Subscribing for more
Thank you, 4 book pages of my book and I didnt understand. I watched 3 minutes of your video and now I got it. Thank you
Glad it helped!
Thanks so much for this! My actual textbook doesn't seem to do a good job of showing examples... I needed help on the third example and you nailed it! Thanks!
Thank you so much, I never thought I would understand this in 15 Minutes.
Thank you so much u cant believe how much this helped me preparing for my finals ❤️❤️
You are welcome! Thanks for watching.
Nikolay's Genetics Lessons thank you
This video is very useful to me as a breeder because I see COI in dogs pedigrees. ❤
Do you know that I have a playlist - dog's breeding? Check it out.
One of the best videos. Explained very well and easy to understand it. Thanks a lot.
I have many more videos on this topic with more complex examples.
Yes I will watch but as someone who do not have scientific background it takes me sometime to understand it but I am really interested in COI. Can you please tell me do you explain " Weight's or Hardiman's COI?
I am Breeding dogs and I see COI in the dogs pedigrees and that is why I want to learn about it. 😊 By the way in the second example should the answer be 1/64? Or am I wrong?
I´m very happy about finding your channel! You have helped me a lot already. Enjoy your day, thank you.
Thank you for your explanation. I'm able to solve my exercise related to pedigree analysis
thank you so much. it was easy to understand and after a bit of practice it was fast .
Thank you for this explanation! You sure are gna making me pass my finals👍🏾
Happy to help!
You are my saviour!!thank you so much. You explained it clearly and easily⚘
Glad it helped!
Easily understood sir. . thank you sir 🙏keep doing..
Keep watching :-)
Thank you very much for your explanation. It was clear and easy to understand :-D
Getting ready for the genetic counseling boards. thank you.
Thank you so much sir...ur all videos on imbreeding helped me a lot sir....
Thanks, you have enlightened me!
Thank you for your video I really enjoy learning about genetics. I have a question. Say I wanted to systematically check every individual recessive allele in an individual mouse. It's my understanding that you could use line breeding to increase the inbreeding coefficient. So breeding daughter back to father after 5 or more generations should bring you close to 100% coefficient. And at that point majority of the genes would be homozygous.
Now say instead I made a cross between two unrelated mice. And then I took 5 daughters from that one pairing and bred them all back to the father. In theory the majority (near 100%) of the fathers alleles would be represented as homozygous across all grandchildren children but the inbreeding coefficient of each individual would only be 25%. Is this correct?
These videos might help you:
Simple Inbreeding Problem and Solution th-cam.com/video/WK-IVGvvDUU/w-d-xo.html
How to Find Inbreeding Coefficient (advanced problem) th-cam.com/video/BH07HbEkx6s/w-d-xo.html
Thank you so much! Very clear description!!!
You're welcome!
Thanku very much sir....
Very easy trick to solve the problems....
Great explanation. But I have a question. What if the common ancestor appears multiple times in the pedigree? For example:
A appears on the fathers as the great grandfather but on mother's side as the father AND grea great grandfather. How would I count that? As one sire appears three times in a pedigree?
Do I only take the closest one to the mother so the father?
I have many more examples of inbreeding - just search my channel.
Thank you
Clear Explanation🙌
You are welcome
MAN ! ! thank you so much .. but sometimes its 1/2 and sometimes solid 1 .. so what the differences ? because this part a bit not clear
I have about 100 videos on this topic - just watch more videos and you will understand how it works.
Thanks very much. Well explained n simplified
Glad it helped
please in our lessons they did the same like you did but for exemple they did (1/2)6 but thery multiplie the result to 4 they said because they are 4 possibilities and i didnt understand when we mutuplie the inbreeding to a number in which case and how
Just watch my other videos in "inbreeding" playlist.
@@GeneticsLessons which video please
I have many -any which have "inbreeding" in their name.
Thank you so much! Its helped me a lot.
is this wright or handimans method?
Watch my new video: How closely Adolf Hitler's Parents we related? th-cam.com/users/shorts8kajiIuUwxw
I realize this video is 7 years old. BUT I can't find the answer to my question. Though I haven't watched every coefficiency video you have. I breed goats and I am just learning coefficiency in breeding. Thank you by the way for making these videos!
I have a diagram I'd love for you to look at. But no way to send it to you.
I have many more examples of inbreeding - which covers basically 90% of all cases. Please check the folder "inbreeding".
You may send me a link to google doc - or write to my email which you can find in "about this channel".
Can i use that to calculate inbreeding in humans..?
Yes.
Thank you very much...it was helpful 💖
You're welcome 😊
Thank you so much
I finally understand this
Glad it helped!
What does it mean if "No common ancestry was found in 5 generations"?
Same ancestor from both mother and father side.
What does it mean when the numbers are bigger or lower? I mean in your example baby no2 is 1/32 and baby no3 is 1/16 . Dose it mean that baby no3 is inherting more from thier parents and ancestors ?
Dose it have anything to do with passing and pushing harmful genetics?
The bigger the number the bigger probability to inherit SAME allele . Say probability 1/16 is bigger than 1/32.
@@GeneticsLessons Nicolay
I have a hw problem that starts with 2 separate lineages that eventually come together...and im very confused
Check my playlists - I have tens of videos on this topic.
What if some individual already was inbreeded? For example, what if individuals C and A in your third case were inbreeded. Lets say C had 0,5 and A had 0,25. What then?
Than it would be reflected on inbreeding coefficient you have to multiply by this inbreeding numbers.
Thank you sir.
its easy to understand... thank you
Very helpful!
Thank you. Ochin intereshna.
You are welcome! Thanks for watching.
thx bro that's really useful
Glad it helped
This is amazing. Thanks!
You're very welcome!
thanks so much really interessting
You are very welcome
Thank you so much !
Today, I am starting a new series of short videos debunking the 'Out of India' theory.
th-cam.com/users/shortsnv3YrBrGXdU
Thank you so much❤
Thank you very much
Mannn u r the best
If offspring “I” produce offspring Male (M) and Female (F) and inbred produces offspring (O). What will be the inbreeding Coefficient of (O). Thank you awesome videos. Subscribing for more
Watch my new video - How to live much longer: th-cam.com/video/nW4ma5Y5liE/w-d-xo.html
Amazing!
Thanks!
Русский боженька, спасибо что вы это объяснили
Пожалуйста. У меня еще есть много видео на эту тему с более сложными примерами.
Am learning here
А почему не на русском??
Всетаки строительство 2000 церквей за последние 5 лет не прошло даром :-) Плоды не заставили себя долго ждать.
explaining how u get the 1/8 or 1/32 would be of great help.
This is exactly what I do in this video.
Here is another video on this topic: th-cam.com/video/nePPKuwphn8/w-d-xo.html
Вам нужно работатт над произношением. Сильный русский акцент на английском - это что-то ужасное. По себе знаю) А видео очень информативны!
Я работаю, у нас в университете полно иностранцев которые говорят с акцентом - и ничего ужасного..
Helpful
Now I know how I can marry my chickens!
thank u
You're welcome!
how is 1/32 + 1/32 = 1/16??? please help
1/32 +1/32 = 2/32 = 1/16
same as 1/4+1/4=2/4 = 1/2
Hello Nikolay, please check your Gmail inbox...
Ok, I will take a look.
Did you take a look?
Nicolay
Watch my new video:
"Inbreeding and Loss of heterozygosity explained" th-cam.com/video/5NYEJ1XbhQ4/w-d-xo.html
New video: Pedigree vs. Arrow diagram (path analysis) th-cam.com/video/4HeLMpQra7Y/w-d-xo.html
Nicoli
your accent is so hard
Watch my new video:
Adolf Hitler: Genetics vs Eugenics th-cam.com/video/D7cFfS3KfY0/w-d-xo.html
daddy nikolay
If Nikolay was your daddy, and you made a baby with him, what would the coefficient of inbreeding of that baby be?
thank you so much
You're welcome!
Thank you so much
You're most welcome