Stanford MD, Latha Palaniappan, on How Your Genes Affect Your Response to Medication

Presented by The Stanford Health Library and The Stanford Center for Asian Health Research and Education
There are known differences in drug metabolism, outcomes, and side effects across racial and ethnic groups, and not everyone responds to medications in the same way. A medicine that works well for others may not work well for you, resulting in significant side effects. In the US, adverse drug reactions cause a great number of hospitalizations and are a leading cause of death in hospitalized patients. Pharmacogenomics, or individualized drug therapy, can help us prevent dangerous drug reactions by pre-identifying at-risk patients. Pharmacogenomics analyses can study your unique genetic profile to determine which medications are likely to help you or harm you, before you even take them. Through this avenue of precision health, we can tailor medical care to every individual, and provide every patient with the right medication at the right dosage at the right time.
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Speaker:
Latha Palaniappan MD, MS, is an internist and clinical researcher. Her research has focused on the study of diverse populations, chronic disease, and prevention. Dr. Palaniappan specifically seeks to address the gap in knowledge of health in Asian subgroups and other understudied racial/ethnic minorities. During her time at Palo Alto Medical Foundation (PAMF) as the Medical Director of Clinical Research, she led the organization-wide initiative to collect patient race/ethnicity and language information, enabling PAMF researchers to conduct disparities research using electronic health records. She was the co-founder of PRANA, a South Asian Wellness program. Her current work examines the clinical effectiveness of structured physical activity programs for diabetes management, as well as best exercise regimens for normal-weight diabetics. She was recently awarded a Midcareer Investigator Award by the National Institutes of Health to provide mentoring to junior clinical investigators in the conduct of patient-oriented research. She is currently working on implementation of evidence based genetic and pharmacogenetic testing in Primary Care Clinics as the Scientific Director of Precision Genomics and Pharmacogenomics in Primary Care. She is the Faculty Co-Director of the Stanford Biobank, designed to accelerate translatable scientific discoveries. She co-founded the Center for Asian Health Research and Education (CARE) at Stanford in 2018.

[@SKARTHIKSELVAN]

All the best for your research.

[@bahar23]

Can genomics analysis be used to lessen pharma responsibilities with regard to adverse events of a patient?

[@bahar23]

How this impacts mix race people?