First Child To Receive CAR T-Cell Therapy Is 10 Years Cancer-Free
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- เผยแพร่เมื่อ 10 พ.ค. 2022
- Emily Whitehead was diagnosed with acute lymphoblastic leukemia when she was 5 years old. After two years of unsuccessful chemotherapy and rapidly declining health, she became the first pediatric patient in the world to receive CAR T-cell therapy. Whitehead, along with her parents and doctor, joins the 3rd Hour of TODAY to celebrate 10 years of being cancer free.
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#Health #Leukemia #Cancer
Congrats to Emily for 10 cancer-free years! The work that the foundation is doing is tremendous.
Königsberg is German! West Thrace, Thessaloniki, Burgas, Aleppo, Mosul, Kirkuk, Batumi, Cyprus, islands, Crete will be Turkish lands! We will take our lands back to it's real owner we will take them from occupation! We will take our old lands back! Real Turks are coming again!
So after 10.yrs they are not?
@@yavuzsultanselim4581 Yes, RIP Harambeeeee!
@@cupidok2768 idk if you mean "what happens after those 10 years"
Well..... probably same as now, keep cancer free. But since she is the first person to have recieved it and well... just now has reached 10 years post-therapy there is no data from 10+ years.
She is literally a beacon of hope for all families who have experienced car T cell therapy. My son had very little hope when he relapsed, but luckily he was the fifth child at his children’s hospital to receive this treatment and he hit his three year post car t anniversary a little over a month ago. We are so grateful to live in this time where he was given the treatment to keep him alive.
I am so happy that he is doing well. I am going 6 weeks post CAR T.
@@rizwanchaudhry1632 from india ?
@@nairritesh I am Pakistani living in london.
@@rizwanchaudhry1632 . Hope you are getting better. How was the process and was this after your Bone Marrow Transplant?
My daughter was diagnosed at 3 did 2 years of chemo and went into remission. She relapsed 8 months later and did the reinduction, did a round of blinatoumamab and both failed her leukaemia was at 88% we had to make an end of life plan for her in case she didn’t make it to the car T cell therapy and she has now finished that the 3rd child in Australia to receive it and we just got her results today that she is again in remission I hope that her story turns out like this girls.
Praying for your daughter, she's strong, i hope all goes well for her.
Thoughts & Prayers 🙏🏼
Congrats to your daughter with her remission! I hope it stays that way and that she lives a long and healthy life!
Amen
Hoping for the best. Such a Roller coaster of emotions, plans, health scares.
Congrats to Emily! A friend of mine relapsed with ALL and after an unsuccessful stem cell transplant received TCELL therapy as well, now they’re doing well too. Truly revolutionary therapy, I’m so glad that it exists.
So glad she is doing alright. Praying that she continues to be healthy and cancer free!
Thanks to Emily and her courage, she paved the way for countless children around the world find options after a time where there are no options.
Congratulations on being cancer free for 10 years! I hope and pray that you continue to be cancer free for the rest of your life, and go on to have a wonderful future ahead of you beautiful Emily! :-)
Congratulations Emily for 10 years cancer free 💕 I’m a cancer survivor too 10 years cancer free 👍🏼😊
Thank you Emily. Because of your success as well as others, my husband's T Cells are being manufactured right now to treat his chemo refractory Philadelphia Chromosome Positive B-Cell Acute Lymphoblastic Leukemia. As recently as 8 years ago, Car T Cell Therapy wasn't approved for my husband's type. This gives me so much hope!!! ❤❤❤
she's a miracle, 11 years cancer free as of 10 May 2023, keep fighting!
She's a beautiful young lady I'm so excited that her parents took that opportunity to not only save her life, but the life of many. They should name it after her. Enjoy your life beautiful.
Delighted to see this story. The Whiteheads are amazing. So happy for Emily and lovely to see her all grown up!
I read her story on caring bridge when it was happening and was so scared that she was going to die. These parents are so brave and amazing to stop at nothing to save their daughter. What a group of amazing doctors for their lifesaving research. Best wishes to Emily. She is a lovely young woman and deserves the absolute best in life. She is an inspiration.
Amazing doctors
Had something like that went i was 9 year old i feel in the park and my let got big in the back and i remember that i told my wonderful mother she took me to the hospital and did check me and I had a tumor and thanks to god and my wonderful mother and the doctor day took it out and now I'm going to be 52 tomorrow is a blessing I'm ok and I'm a roll model and beautiful and and my on way im have a wonderful husband and my princess child and my wonderful mother i go to visit her and I'm grateful and I'm helping others people like children and volunteer went day nead me that why emely story it got to me ok and day save my leg thanks to my mother and the doctor and god
This is beautiful. Gives others and their family with similar diagnosis so much hope. Congratulations to this beautiful young lady and her family and thank you for spreading awareness of this new treatment. 🙏🏻💕
That is an amazing story and outcome. Congratulations Emily.
So happy for Emily, her family, dtrs & researchers in the pipeline that made this happen. Best wishes for Emily!
What a great family. Emily you go girl!!!!
So beautiful girl
God bless her and her mom and dad
Proud to work in this field
so happy to see her be 10 years cancer free and so thankful for these cancer researchers.
I'm so glad it worked for this beautiful young lady. My mother got blood cancer from this treatment and is now fighting for her life.
As a scientist in CAR T cell research, i am glad that it is giving hope, I would like ever cancer patient be lucky like Emily,but it breaks my heart to see lots of lives could be saved if were cost effective except for those companies that care more about money than saving lives.
totally
You’re right it is really expensive unless you’re eligible for a trial, but reading your comment I really doubt you’re a CAR T cell research scientist.
Your writing is a bit illiterate for someone who is claiming to be a research scientist, and what you’re saying in your comment is inaccurate, and again if you truly were a CAR T cell research scientist you’d know the process of CAR T cell you wouldn’t be making this comment. You are basically saying that money is the only reason that all cancer patients are not able to have this therapy and save their lives, and if you really were a research scientist to this therapy you would know there are so many more factors as to why people are not eligible for this treatment other than money. One of the reasons is that CAR T cell therapy is not effective for any or every cancer but it’s only effective and approved for blood cancers. But as a CAR T research scientist you would have known this right?
@@tammyslaughter9587 if you really know about scientific literature then you should have understood when i said "lots (lots doesn't mean all cancer patients) of lives could be saved" means for those patients it would work but is not available to them, and they are in millions". Penicillin could save more lives if its allergen epitope is replaced, it doesnt mean penicillin could save people with brain tumor, but means only those who had bacterial infection which even a stupid person can easily grasp. you just trying to be over smart when you are otherwise. You are just trolling over the internet finding people on whom you could vent your personal frustration by making them feel same like yourself.
@@acesin-et7pp my comment to you has nothing to do with with your use of “lots”, you’re just deflecting. Understanding what you mean when you say”lots” has absolutely nothing to do with scientific literature. It doesn’t matter whether you think I’m trying to be “over smart” I’m not the one claiming to be a research scientist for CAR T cell therapy. Since you are claiming to be a CAR T scientist please explain which patients this works on and how to get treatment for CAR T cell.
This is great hope she has a full happy life
What an amazing story, and what a lovely girl
Congratulations so happy for you all
That's awesome! I wish more people, especially children could have this story! She is so pretty!💘
Congratulations Emily! You are an inspiration. I’m a huge runner and am going to dedicate my next run to you
Happy to see her healthy and fine 😊
Congratulations,
Congrats to Emily
great job emily!
If anyone looking to get CAR T and can’t afford it please look into India, they recently started CAR T and it’s cheaper compared to west. I read that it costs 20-30,000 dollars. But they are bringing it down to 10,000 depending on the amount of patients. Hope my message reaches to people in need.
Amazing!
This is amazing! CONGRATULATIONS EMILY! I have Car T therapy in the near future and im looking forward to being CANCER FREE AGAIN!!!!
Congratulations Emily cancer free godbless you and your wonderful parents and thanks to god you make it and allwallys good to help somes children's awesome blessing
These hospitals are doing amazing things, gave this family a new life, what a beautiful child.
Love it!!!!! Praise the Lord we found a treatment!!!😍
CHOP is amazing! One of their clinical trials saved my life too
That's fantastic news! Congratulations on being cancer-free! Reaching this milestone is a significant achievement, and I can only imagine the relief and joy you and your loved ones must be feeling right now. Remember to celebrate this victory and take some time to appreciate your strength and resilience throughout your journey.
Amazing what science can achieve! Congratulations!
Bravo to scientists!👏🏼👏🏼👏🏼
Sobbinggggg
I have to say that’s incredible. Gained an immunity to cancer after taking the car-t cell therapy. Good for her.
Great story 👏 gald she is 10 years Free in many more
Really great success in Cancer treatment.
Thank to these great people and scientists to help others and promote life better than those bring death unfortunately
Go Emily! I’m 11 months free after CarT !
Children’s hospital of Philadelphia is the best hospital and living in Philadelphia is wonderful chop has helped me so much my aspiration to work at chop is big
Thank you to Emily and her family, for blazing the trail! Our granddaughter is now 4 years Cancer-free only because of Car T.
Hi Dr. Grub, if you see this:
can you try to get in touch with Dr. Jeff Boris at CHOP cardiology, Dr. Blair Grubb at Toldeo U (director of Cardiac Electrophysiology/ cardiologist, head of autonomic disorder fellowship training program UTMC, and innate immune system pathophysiology researcher), Dr. Anne Maitland at Mt Sinai- NY (MD& Ph. D at UPenn, professor of Allergy & Immunology/ clinical Immunology at Mount Sinai), and/or Lauren Stiles at Dysautonomia International.
I'm a CHOP grad- now adult patient living with post EBV dysautonomia and severe mast cell activation related idiopathic anaphylaxis (and related immuno-mediated autoimmune disease) and CHOP diagnosed classical ehlers danlos syndrome (the hypermobile type, previously type 3, is expected to be as common as 1 in 33 but rarely dx).
There's several of us- once peds- now adult post viral immuno-mediated chronically ill patients with connective tissue disease presentation consistent with EDS, Marfans, sticklers, hypermobility spectrum disorder, and similar disease pathogenesis.. Including a large majority of post viral blood cancer survivors of Burkett's lymphoma, ALL, AML, aplastic anemia, mastocytosis, etc.
There HAS to be a link with risk of developing these post viral blood cancers and underlying connective tissue disorder.. just look at Emily's dad.. he's definition marfanoid habitus phenotype. The other side is neurofibromatosis type 2 which is also mast cell mediated immunomodulated growth. Many of us who have post viral autoimmunity related dysautonomia respond positively to HD iVIG product and gleevac; which further suggests similar underlying mechanism of disease.
If not to evaluate the underlying connection, at least please try to reach out for the sake of post chemo autonomic neuropathy management. I think it could lead to better application in use of the CAR T cell to a wider and huge spectrum of further understanding of the shared underlying Mechanisms that can be cross applied.
Thanks!
You should probably write this somewhere else. I don’t think he’ll be checking this video’s TH-cam comments. Try to contact these people by email or something.
A blessing from God! Praise Him!!
Finally some great news
I hope you are answering comments...
What is the immunotherapy treatment called ( CAR T therapy ) Is this in the same as, Ippivilomab, Yervoy, Keytruda? Sorry about the spelling!
I'd appreciate an answer!
Thank you
love and light to all Dr's , Scientist and family here♡
Mary
With CAR T cell therapy you basically take the patients own t-cells (which are part of the immune system) and genetically alter them. They receive cancer specific receptors which then detect cancer cells. Once they can identify cancer cells, the immune system works just as it would when fighting for example the flu.
Usually, the immune system is enabled by the cancer so it will not detect cancer cells.
I hope this helps :)
No it is not, totally different process. Immunotherapies have been around for twenty plus years and has nothing to do with CAR T cell therapy.
Yay💖👍🏼💐❣️🏆
Everyone should be honoring Dr Grupp and his staff at CHOP which is the best childre’s hospital in the world
Emily got some killer eyebrows!
Thanks for all you do dr oiwoh on TH-cam you have a good heart keep on the good deed towards getting people cured may God always blsss you.🙏🙏.
Science is amazing.
No mention of the $800,000 US price tag...
I read a book 20 years ago by an oncologist that taking zinc will increase the t-cells.
Congratulations! How about the poor? Can they access? I wish the doctors can train the world & make it free for cancer patients to make it.
In countries with insurance its free...
How about the poor? Good thing we have numerous charitable organizations to help like St. Jude's. Also, insurance, like the other guy said. It's only non-creative people who cannot think of any of these great, simple solutions.
There’s no way cancer patients can modify their own T- cells to fight their cancer. It’s a very expensive process with very expensive machines and specialized bio labs.
Unfornately its shortterm 10,20 years max
No...... generally you are really cancer free after these..... where do you get your info from? Please give me your source i would like to know.
@@JustMe-12345 Actually you’re incorrect, many people relapse after having CAR T cell therapy and some have had it more than once. Many have gone a few years, or months after CAR T and relapse. Having CAR T cell does not guarantee a cure, there are just too many variables for each patient. I got my source from my hematologist/oncologist in preparation for CAR T cell therapy in Texas. But you can find whatever info you are wanting to know from MD Anderson, Mayo Clinic, Moffitt Cancer Center, Johns Hopkins, Dana-Farber, Sloan Kettering, Stanford etc. they can provide information for CAR T therapy. I am also part of a CAR T cell support group, so I get a lot of my info first hand from people who are in different stages of CAR T Cell therapy. But you are free to believe whatever you choose.
Cancer is normal their are all types of cancer someone will get in life.
Am i the only one who is waiting till they post the ST4 interview
So does everyone get this treatment or ???
No.....only those that will benefit from it (not all kinds of cancer will), and only if they will benefit more than from others. And maybe only after other therapies have failed
This treatment is best for blood cancers. It doesn’t really work for any other cancers (for now!)
@@JustMe-12345 right this is only for leukemias, lymphomas, and multiple myelomas.
WTF this was 10 years ago? How many people are suffering and dying. And she was cures 10 years ago.what does this cost.
Over a million dollars unless you’re in a trial. This therapy does not come without severe risks that’s why many times it’s the last resort treatment and it is only 40% successful with many people still having relapses. This treatment can cause cytokine release syndrome, which can cause organ damage and death, it can also cause neurotoxicity with many people not even knowing their loved ones or not able to speak and not knowing their own names, although it’s usually reversible. Plus if you survive treatment whether it is successful or not people after treatment usually will suffer from B-cell aplasia for the rest of their lives. So before you get all angry about it being around for awhile it is still being used cautiously for certain people with blood cancers.
Praise the Science!
😊😊👍👍👍👍👍👍⭐⭐
What about for pets?
i would not do that...... they wont understand why we must make them suffer....
And most therapies wont exist for them, and wont be made either
I just found her Instagram account
Science is great... Does alot of things a God can't.
Slowly but surely 1 case ata time this will change when the industry stop seeing cancer as a very lucrative blood y duty business around the world ,..will change
Having you as a trusted Dr was a super blessing in my life because you did what no other Dr could do,I nearly thought it was the end but you Brought out a situation with your herbal supplement thank you #doctorogie
HMM THIS WAS 10 YEARS AGO AND SO WHY THEY TRYING TO PUSH THIS NOW , AND 5 YEARS AGO WHt?
because she made a picture every year to celebrate that.....and 10 years is usually an anniversary that is celebrated..... so they are celebrating it. You are making it out to be something it is not
But tremendez congrats in remission
2 years at valley childrens and nothing better hmmmhmm
Chemotherapy doesn’t work just do this
Chemo DOES work, and this does NOT work for every kind of cancer (it does well for ALL or other kinds of leukämia, but not in other cancers), and there are other therapies as well (eg some can be treated by hormone-blockers etc
There is not A cure for cancer.....there are a multitude of individual treatments
Well sure, people are going to just jump on having a very risky, and one of the most expensive treatments in the US. Plus you’re usually only eligible after exhausting third or fourth-line treatments of chemo and other blood cancer treatments.
Du bist mein Idol Kimmy-jka.Monster immer in meinem herzen, schon, liebe, wahlen, kulturell ❤ Sie sind einesx der besten Konzerte..sh
Königsberg is German! West Thrace, Thessaloniki, Burgas, Aleppo, Mosul, Kirkuk, Batumi, Cyprus, islands, Crete will be Turkish lands! We will take our lands back to it's real owner we will take them from occupation! We will take our old lands back! Real Turks are coming again!
God and his unintelligent design almost ended this young women...but science....cell biology...the acquired facts and understanding of evolutionary theory...genetics....SCIENCE saved this women from the unintelligent lunacy of Jesus, Allah etc.
He said those this work for everyone
"No"
Yeah if a family is broke it doesn't work for them
It does not work for all cancers. She had ALL i think (acute lymphatic leukemia), for solid cancers there are other therapies that work better, idk if this does not work there.
And..... there are countries with insurance where how much you have does not matter.
Sounds expensive
Poor kids couldn't afford that!
I'm pretty sure these evil doctors
Could careless about other kids
Now that they know this treatment works!
This little girl was just lucky to be a genepig .
........ it is being given to all patients that would benefit from it, no matter their financial standing.
And her being "genepig"..... well she would have died otherwise. Thats how new treatments are found: in studies they see what is promising, then they do clinical studies where patients (that again.....would die otherwise because all established options dont work) recieve it.
And why would these docs be "evil".....they are literally saving lives
Poor kids... no they cant afford it, thats why most developed countries have working insurance system where they wont need to pay for it out of pocket
Thank you Emily. Because of your success as well as others, my husband's T Cells are being manufactured right now to treat his chemo refractory Philadelphia Chromosome Positive B-Cell Acute Lymphoblastic Leukemia. As recently as 8 years ago, Car T Cell Therapy wasn't approved for my husband's type. This gives me so much hope!!! ❤❤❤
Thanks for all you do dr oiwoh on TH-cam you have a good heart keep on the good deed towards getting people cured may God always blsss you.🙏🙏.