I read every Clinical Study on Lion’s Mane & Brain Function: Does it Work?
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References (Copy & Paste DOI into Search)
[1] doi:10.2220/biomedres.40.125
[2] doi:10.3389/fnagi.2020.00155
[3] doi:10.1155/2019/7861297
[4] PMID: 36582308
[5] doi:10.2220/biomedres.31.231
[6] doi:10.3390/nu15224842
[7] doi:10.1002/ptr.2634
[8] doi.org/10.101....
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#cognition #cognitivefunction #lionsmanemushroom
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I'm a veteran, was actually addicted to alcohol and cigarettes. I suffered severe depression and mental disorder. Got diagnosed with cptsd. Not until my wife recommended me to psilocybin mushrooms treatment. Psilocybin treatment saved my life honestly. 8 years totally clean. Never thought I would be saying this about mushrooms.
I love hearing great life changing stories like this. I want to become a mycologist because honestly mushrooms are the best form of medicine (most especially the psychedelic ones) There are so many people today used magic mushrooms to ween off of SSRI medication- its amazing! Years back i wrote an entire essay about psychedelics. they saved you from death buddy, lets be honest here.
Can you help me with the reliable source 🙏. I'm 56 and have suffered for years with addiction, anxiety and severe ptsd, I got my panic attacks under control myself years ago and they have come back with a vengeance, I'm constantly trying to take full breaths but can't get the full satisfying breath out, it's absolutely crippling me, i live in Germany. I don't know much about these mushrooms. Really need a reliable source!! Can't wait to get them
YES very sure of mycologist Predroavaro. This treatment worked for me. Helped me got rid of my anxiety and BPD.
Thanks for sharing your story. That's rough I sympathize. Save your health save your mind. Life is better without heroin, cocaine, alcohol and cigarettes. And you have more money in your pocket. God bless everyone who has rejected the devils intentions to be addicted to alcohol and cigarettes etc which can cause so much damage to health. I will pray for you all.
How do I reach out to him? Is he on insta
I don't know. All I can say as someone suffering from central nervous system disease is that Lion’s Mane lifted my "brain fog".
I'm so glad you found some help! Unprocessed Cocoa also has good results for some.
It lifted mine after chemo, i was surprised.
did you eat the actual mushroom, or did you take lions mane supplements/pills? thank you
@@novanoskillz4151 i took the capsules.
@@novanoskillz4151 I'm taking 2000mg pills daily
time for a mushroom series!!
Reishi, cordyceps, chaga, turkey tail!!
yessssss pls 🍄
Please do!
At this moment in time, I don't think Nicholas has mushroom in his schedule to do it. Maybe in a couple of weeks, but a series on fungi would surely spore up some interest! I wasn't so sure about a mushroom series at first, but you've chaga'd my mind! The morel of the story is each mushroom has its unique benefits, and personally I don't shitake the time to research them all.
Interestingly, the academy of fungi and mycological sciences have just released a study on Lion's Mane and it being useful with helping treat late-onset cognitive decline. Maitake on the study, however, was some potential bias from funding groups - specifically the Better Glue Can Council! Seems they were hoping for some memory-enhancing adhesive properties.
The mane takeaway, though, was positive - the Lion's Mane group showed a significant improvement (6%) in cognitive function compared to the placebo group. 🍄
Interestingly the other day whilst at the coffee shop, I ordered a mushroom lattle. The barista said "Here's your 'Gobble Power' latte with a touch of turkey tail! this bad boy will have you tackling that mountain of emails faster than a greased turkey on Thanksgiving!".
I replied "Uh, is this actually coffee, or just blended turkey feathers?". ☕
He said "Of course, don't be silly"
Relieved I said "Phew, good to hear! Don't want any 'fowl' surprises in my morning brew."
Next time I go I''ll try that Enookie cookie, apparently it has a sweet and savory flavour with a hint of fungus. 😋🍪
Maitake
@@AstonAcademiaHericeum 👁️a real chestnut of a comment.
I'm not shocked by the first Caveman who ate a Jalapeno, but rather by the second. He sees the first guy on the ground, writhing in pain and says, "Hey, give me some of that!"
The second one was probably like "I'm not like you dude, I can handle my spice" (the same guy who came up with walking around in fur shorts during the ice age)
Depends on who ate it first
If it was me he saw first, he'd see me obsessively eating the jalapeños with every food I eat, ranting and raving about how good it taste!
I'd wager it became a test to your man card back then 😂
@@Aldebaran-pw9bb man card?
Never known anyone to like hot peppers more than my mom!
It's a taste thing, not a testosterone thing.
Jalapeños were bred by humans and i think the first domesticated Chillies propably weren't that hot.
I imagine the diversity of responses to Lion's mane from "It cured my brain fog" to "I didn't feel anything" to "It put me in the hospital has to do with nerve cell growth regulation. I'm no biochemist or physician, but if I had to take a shot in the dark, people who benefit have nerve cells that are resistant to growth for some reason and lions mane provides the stimulus for growth they're missing. The no effect people either don't need the stimulus or are not sensitive to hericenones and erinacines. As for the people hurt by it, they might already have overactive, overconnected nerves, and the lion's mane makes it significantly worse with all sorts of ill effects caused by excess nerve growth. Because everyone would have different absorption, sensitivity, and need of the active ingredients, it would be hard to pin down an actual pharmacological effect without statistically very high powered studies.
It could also very well be related to microbiome changes.
Coinciding with this, if we take a look at something like Saint John's Wort, there are documented cases where it helps some and doesn't others. The same case might be with Lion's Mane. My own experience and experiments with it so far have seem to indicate an enhancement in my cognitive function, but all I can really currently do is a self case study.
True, the issue with hypothesising mechanisms outside planning your research is that people easily pick up on random anecdotal experiences and someone pondering a mechanism and conclude that if someone can think of a way it could work, and someone definitely thinks it changed their life, it must be a fact. The problem is getting all those studies in to show if there's an effect. And to be fair showing supplements having real effects is a pain in the ass. Usually you can make an educated guess that if drug companies aren't selling a product with it on prescription drugs, it might not be more than a nice feel from changing lifestyle and believing you're changing things for better. But at the same time if you're not scammed with the price, that's a real effect as well.
Could make sense. I took it once in a capsule form, had quite insane brainfog slowly fading over 2-3 weeks. Never doing that again. I am a bit eccentric...
@@Kalleskaviarriddare I had a similar effect when I tried it. I was spaced out from it. And it did take a couple of weeks after quiting for the effect to stop. It definitely isn't for me.
Lion's mane, like other mushrooms including oyster mushrooms, contains Ergothioneine which is credited with clearing amyloid plaques from the brain (associated with neurodegenerative diseases). Could we get a review of the studies looking at Ergothioneine? It's been dubbed a "longevity vitamin" by some.
There aren't much studies about it. And certainly nothing to warrant name "longevity vitamin". Just marketing speeches.
@@user255 I'm not sure where you got that from, but there are a very large number of studies on ergothioneine, going back decades, with a flurry of studies in recent years, some of which I've read myself. You can easily look them up on Google Scholar. They all convincingly point in the same direction. Ergothioneine is an extremely potent antioxidant with a host of significantly important benefits, and our bodies have a highly specific transporter for the uptake of Ergothioneine indicating its importance. It's primarily found in mushrooms. I don't think 'Big Pharma' is aggressively pushing Ergothioneine supplements because of how easily it can be acquired from whole mushrooms, which are quite cheap, and I don't think 'Big Mushroom' is a thing, lol...
@@user255 there are actually many studies on Ergothioneine and mushroom consumption that can be easily looked up using Google Scholar, that all point to Ergothioneine, being a very potent antioxidant, with a host of beneficial properties.
Just a few examples:
Cheah IK, Feng L, Tang RMY, et al. (2016) Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration? Biochem Biophys Res Commun 478, 162-167
Beelman RB, Kalaras MD & Richie JP (2019) Micronutrients and bioactive compounds in mushrooms: a recipe for healthy aging? Nutr Today 54, 16-22.
Smith E, Ottosson F, Hellstrand S, et al. (2020) Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 106, 691-697.
Kameda M, Teruya T, Yanagida M, et al. (2020) Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility. Proc Natl Acad Sci USA 117, 9483-9489.
Zhang S, Tomata Y, Sugiyama K, et al. (2017) Mushroom consumption and incident dementia in elderly Japanese: The Ohsaki Cohort 2006 study. J Am Geriatr Soc 65, 1462-1469.
Feng L, Cheah IKM, Ng MMX, et al. (2019) The association between mushroom consumption and mild cognitive impairment: a community-based cross-sectional study in Singapore. J Alzheimer's Dis 68, 197-203.
Yasaaswini Apparoo, Chia Wei Phan, Umah, Rani Kuppusamy, Vikneswary Sabaratnam (2022) Ergothioneine and its prospects as an anti-ageing compound. Experimental Gerontology Volume 170
Bindu D. Paul (2022) Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxidants & Redox Signaling. Volume: 36 Issue 16-18
There are many, many more… But I don’t have anywhere near the level of expertise as Mr Nicolas Verhoeven to evaluate all of these studies, hence my request.
there are actually many studies on Ergothioneine and mushroom consumption that all point to Ergothioneine, being a very potent antioxidant, with a host of beneficial properties.
Just a few examples:
Cheah IK, Feng L, Tang RMY, et al. (2016) Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration? Biochem Biophys Res Commun 478, 162-167
Beelman RB, Kalaras MD & Richie JP (2019) Micronutrients and bioactive compounds in mushrooms: a recipe for healthy aging? Nutr Today 54, 16-22.
Smith E, Ottosson F, Hellstrand S, et al. (2020) Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 106, 691-697.
Kameda M, Teruya T, Yanagida M, et al. (2020) Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility. Proc Natl Acad Sci USA 117, 9483-9489.
Zhang S, Tomata Y, Sugiyama K, et al. (2017) Mushroom consumption and incident dementia in elderly Japanese: The Ohsaki Cohort 2006 study. J Am Geriatr Soc 65, 1462-1469.
Feng L, Cheah IKM, Ng MMX, et al. (2019) The association between mushroom consumption and mild cognitive impairment: a community-based cross-sectional study in Singapore. J Alzheimer's Dis 68, 197-203.
Yasaaswini Apparoo, Chia Wei Phan, Umah, Rani Kuppusamy, Vikneswary Sabaratnam (2022) Ergothioneine and its prospects as an anti-ageing compound. Experimental Gerontology Volume 170
Bindu D. Paul (2022) Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxidants & Redox Signaling. Volume: 36 Issue 16-18
There are many, many more… But I don’t have anywhere near the level of expertise as Mr Nicolas Verhoeven to evaluate all of these studies, hence my request.
Anytime someone declares a single super food for longevity you should be skeptical. It's diversity that's important, never a single food.
I had poor memory , so much so i planned to go to the doctors for checks. I then ordered Lion's Mane, and it has certainly helped improve my memory, there is no question about that for me.
My personal experience having autism and memory problems, Lion's main increases the number of things i can remember from 4-6 to 15.
huge difference for me.
Are you taking it in pills or food? I’m looking into getting some
@@guillermoalbertopiedra1779
Look into the brand
Look into what extract means
make sure they are trusted and not some imported asian brand that looks legit but is actually made in someones house.
I use power extract to take daily. you can use pills but i find buying bulk powder is cheaper.
sometimes i visit my local apothecary and buy the real deal, mill it with my mortar and pestle and make tea or bake with it.
Is it only lion's mane or some others too? How do you narrow the memory improvements to LM?
Strangely not mentioned is that Lion's Mane is one of the tastiest mushrooms, this is critical to factor in when considering whether to supplement one's dinner with it.
Took the words...A sandwich with these and pink oyster is one of the yummiest!
I just tried some an hour ago cooked a cast iron skillet with some butter and garlic and WoW!
I’ve never had a tastier mushroom, the texture is amazing
These are not available in my country - too many benefits for ordinary people they don’t want us to have. Medical professionals don’t like it.
I know somebody who took this stuff everyday for a year hoping to fix hippocampal damage and subsequent memory loss from alcoholic cirrhosis.... Apparently it worked quite well... Anecdotally..
Lions Mane gives me vivid dreams and wake feeling rested.
why vivid dreams?
My dog (14+ years old) has Canine Cognitive dysfunction. He did sundowning and because of it we hardly got any sleep during the nights because of his wandering around, crying, tugging stuff off shelves etc. or just standing around even though he was exhausted. I read about Lion's Mane and started giving him 1/4 teaspoon on his food. A short while later it started to work and now he's behaving like his normal self again, sleeps through the nights again, is playful during the day. He's been on it for 1 1/2 years now, I will never stop giving it to him, it made a big difference.
Canine Cognitive Dysfunction? Does everything have to have an idiotic medical name? How bout from now on you just tell everyone you have an old dog.
@@SilverGrizzlyhaaaaaateer
@@SilverGrizzly Grumpy alert. Go take some Lion's Mane, just might help.
@@phammond8155 Yikes! And I thought my picture was of a horseface!
@@SilverGrizzlyyou really read this amazing comment (whether true or not) and had the idea to be the arrogant commenter that no one likes? great for you… 🤦♂️
I used to work for an importer exporter of wild edible foods and wild picked mushrooms were the company’s main focus. I didn’t know anything about mushrooms or what they could do and how healthy they are for your brain and body. My boss suggested to his employees to take a few mushrooms home and have them with dinner. After a few weeks I could definitely notice a difference. Cognition was most affected.
Was it positive difference or negative ??????????????
@@naughtyUphillboy positive.
Did you cook them or eat them raw? And did you eat them in other foods or by themselves?
@@caseyvallett8953 In general, you shouldn't eat mushrooms raw. Many of them have a lot of chitin in them which your body can't really digest. Cooking them breaks this chitin down.
@@mitzee8621 @caseyvallett8953 on top of that some mushrooms are dangerous if not properly cooked, like morels for example, and mushrooms grown outdoors/foraged usually also have bugs and stuff in them that you probably want to cook down.
Combination is key! And cut out simple sugars. If you feel sharpness slipping, add Creatine, Cordycepts to Lions mane. Some protein supplements / foods worsen brain fog (unless taken with antioxidants). Collagen or eggs for example, take with some tomatoes for lycopene or blueberries. Massive difference in clarity.
That "How to Lie With Statistics" graph is classic. So glad to see anyone mention effect size. Smart work!
You are my definition of a wholesome rolemodel!
Thank you just for being you. 🙏♥️
Before I do anything I always ask myself what would this guy do in place? Since I started to sing that, my whole life has turned around. He is a great role model, I play his videos for all the neighborhood kids and encourage them to model their lives off of his
@@campfirestories6681
Glad you found your way to happiness bud.
Damn. Maybe it's all placebo, but I really do notice a difference on my speech in particular. Word retrieval and a stronger, more vast vocabulary, seem to flow without effort.
Choline does the same thing for me.
same. that's been the most noticeable change after 6 months or so of 3 daily Lion's Mane pills. I seem to be able to express myself effortlessly and access obscure words. It's wonderful! I used to really struggle with finding the right phrase.
@@louiss1625 I'm struggling with this
Perhaps it works for people with some need of something which it contains
My neighbour had early dementia. He husband got her on lions maine. Her dementia has all but disapeared.
I’m confused did it disappear? Or not? Lol
'All but disappeared' has simelar meaning to 'almost completely disappeared'
@@joshmeex5937 It's impossible to 100% completely "cure" dementia. It is a permanent diagnosis that is usually progressive. However, what people CAN do is "slow down" its progress, and in some cases, even reverse some of the damage it's done (hence the LM conversation). Which is different from a complete full stop "cure". If you stop whatever treatment is helping, it will no doubt come back.
That's very nice to hear, but what about my shares in Big Pharma dammit.
There's a small study on lion's mane showing benefits on the microbiome. This could very well be related to the mental effects.
Fundamentally, what we need is better placebos.
All foods or whatever can be. Its obviously a mental situation. Those people taking the placebo believe they are taking something helpful . The body responded to the placebo so says the graph. So with years of discipline you can train yourself to believe that all is good.
What has a better side effect profile than placebos?
Great point!
What we probably should do is make a nocebo/negative control group that has people take a fake pill and the substance itself that convinces people it'll worsen the symptom they have and see what it does. Not sure if it's possible but could be something to generate more accurate results?
I took lion's mane for about a month and noticed nothing. It claimed it would increase my REM and intensity of my REM. According to my Apple watch my REM was unchanged.
Same, I went to a farmers market and bought some fresh weekly... No difference. Nothing has changed my brain more than keto+fasting, not even close.
Sleeping without Apple watch (and other smart gadgets close to your body or bed) will better the quality of your sleep. Just try it.
With or without mushrooms
took it for 6 months 6 years ago, noticed nothing
I would be wary of any mushroom that tried to claim anything...
@@mailill why ?
Also, outside of the child mortality, hunter gatherers tend to live longish lives. They actually get through droughts etc better than non-advanced agriculture societies. So the 12 year old grandpa should have a many many more grandkids to come. Probably comes from working an average of 15 hours a week, having a varied diet, incidental exercise and strong social connection. Even that long working week was during hard times. Generally 2 hours... and only if we gave them a word for work because most hunter gatherer societies didn't have a word for work. People back then enjoyed hunting too so their 'work' was more like play.
Medicinally beneficial or not, these mushrooms are DELICIOUS!!! Also, the different names you mentioned are actually different species of the Hericium fungus. They look slightly different, but are all tasty and have the same medicinal compounds.
I didn’t think I would have mushroom for this info. But you’re such a fungi, you made this work
Nice one, Victoria
@@Physionicno
Why would the researchers not have taken the groups off lions mane and placebo and then for another twelve weeks test cognitive function to see if the lions mane group returned to the norm???
That was my question aswell feels incomplete
42 y/o anecdote here. I've been taking lion's mane for years and I can definitely attest to it improving my memory. I recommend anyone curious try it.
I had CPR that saved my life, but the mild oxygen deprivation it caused resulted in my having mild cognitive impairment. I took lions mane for three months before any noticeable results started showing, but it was another six before I could see improvements in objective tests like timed Sudoku puzzles and the ability to read for hours a day without fatigue. I was as objective an experimenter as one can be on oneself, and continue to take it twice a day, every day. 🤷🏻♀️
I keep hearing good things about this Placebo drug, where do I get it?
Lions mane is the only thing I have found that helps my post fusion surgery neck pain. I started taking them for brain benefits and was shocked at how much they help my neck pain. I wish I knew why.
He had the same c6 to c7 fusion. Neck brace caused muscle spasms across my upper back. But, what hurt the most was the donor site for the bone graft, my right hip arch. Man that hurt for a year. Hope you did better than my experience. Thank you for your comments.
I'd guess that it has to do the anti inflammatory effects of lion's mane. Probably many other foods could be helpful with that. Also, staying away from foods that cause inflammation will be key. Inflammation can exacerbate pain in areas that are already in pain.
I'd say exercise would help any of the those problem more than Lion's Mane, I carried the maple logs to innoculate with Lion's Mane into for about a 1/4 mile up 25% Slope. That exercise probably shook the cobwebs out of my brain. 😂
Why would you do that?
@@nadnavlis240 Terrain is unsafe for anything else other than a horse, and I don't have one. I do everything around my place physically and manually.
Do one on Cordyceps Sinensis/Militaris. Lion's Mane, Cordyceps and Chaga are the base of my stack.
A cop saw my Chinese herbal medicine poster in my RV when someone called them on me for no reason.
He asked if i was into mushrooms. I said yes i take rishi and chaga daily for immune system. He suggested lions mane for brain. Been taking it for for a couple weeks. I add it to my meat rub when I season my steaks, lamb and bison. Last night I just threw it in a pot with some beef, portobello mushrooms and onions and made a beef stew.
Portobello mushrooms will give you cancer . Stamets himself has said it.
Stamens study showed cognitive increase of 42-60 bpm. Cognitive beats per minute. That literally means 30% more capacity to think, 30% more words typed per minute and 30% more notes played upon a guitar. His formula is lions mane, niacin and psylocybe mushroom.
Could you send me the study?
Stamens is the mushroom guru
I bet the psylocybe mushroom does most of the job 😄
No answer?
His correct name is Paul Stamets.@@billw6903
Very interesting video. I tried the "best" lion's mane extract for 90 days to help with my memory and anxiety issues but it did nothing for me and was too expensive to try for longer.
I recommend Tommy Chong's CBD for mood disorders like anxiety & depression. Have you found anything helpful for memory?
try fasting and thank me later lol.
I thought people take lions mane for healing and regrowing nerve damage, not cognition. The nerve growth being the most important effect not being addressed feels like an unintentional strawman.
Nerve growing = neurotropic factor.
Anecdotal: I'm 50. I had a TBI (🧠) in '99. Lion's mane seems to sharpen me up. Nothing dramatic, but enough that if I lay off it for a bit, I notice a difference.
I had a TBI 1 year ago and it’s made a big difference for me as well, especially my memory and word recall. What brand do you use? I use the Forage brand.
Glad this was on the extract, which is what most pharmaceuticals are focused on. Great discussion on chitin reducing bioavailability...bravo bravo
Chitin sounds like a slur. "This bar was cool until all the... chitin started coming around."
Fermentation changes everything. So much research still needs to be done on mushrooms
The studies that I have read seem to indicate it increases NGF levels. This seems to align with the effects being pronounced in patients with pre-existing conditions affecting their cognition/neuronal health, as NGF decreases neuron degradation, which should be slow enough in healthy adults to have little effect, unless the study was conducted over much longer periods of time.
Lions mane has done wonders for me and most likely saved my marriage. It has completely taken the anger out of me and I don’t get put anymore.
I love this guy. We could all use more humor in our life!
Can you comment on Turkey Tail mushroom that’s supposedly used to treat cancer? Thx.
Yes!
Not familiar with that
Have heard people try to treat cancer with chaga. Realistically cancer drugs these days are amazing
"Will I die as an adult 9-year-old?" Lol
I feel ~weird~ on Lion's Mane. It absolutely has an effect on my brain but not necessarily a good one. It makes me feel panicky
I never have nightmares, both times I tried Lion's Mane I had repeated nightmares. Interesting to hear others having similar reactions.
I consumed Lion's Mane for 3 months and didn't notice a single difference from taking it before bedtime. Meanwhile, my two cousins reported better sleep, more vivid dreams and more intangible benefits related to cognitive function from taking it. I'm not sure why their experiences were so different from mine, but unlike them, I'm not going to continue this experiment 😅
Have you done drugs in the past?
@@bellickscolfield9180 Never. Why?
were you taking the same brand
@@Freethesnowglobes. I'm pretty sure they ordered it from the same site, so I assume we did.
1:49 can't believe I actually chuckled at your dad joke
ikr 🤣
lol same🤣
i totally chortled
I didn’t.
All "studies" are generously provided by the qualified pharma professionals.
Love your channel. Keep up the good work!
As always, interesting and such fun! 😊
Lions mane feels like it drains all dopamine from my body, even at low doses. Zero drive to do anything. Just lay there for hours
Another interesting name for you. In Chinese, it is called 猴头菇, which translate to Monkey Head Mushroom. I can see the resemblance. It is very tasty as a soup, the mushroom.
You are the Vegeta of science, Nic!! Another great video!
Actually, I am the Vegeta of science.
You guys made me remember the fake presidents video where they go to the haunted house, and Obama corrected Kim Jong Un about Vegeta vs. Perfect Cell.
I would suggest lithium orotate next. Does micro dosing have any benefits?
I stack LM and AlphaGPC and it really helps with memory retention, word recall and sharp focus. It works for me.
How about the fact that the placebo group started out lower than the treatment group, and the two lines are close to being parallel over the entire study.
😂 right? They would prefer to ignore placebo and nocebo because it leads somewhere they don't want to go. No money in it.
I find that it helps to calm me down and puts me at ease.
I agree. It has made me a much calmer person and not push any buttons. I’m a changed person.
I started having my 88yo Mom take it last year after we noticed a cognitive decline in her. This winter I had her diagnosed with early to mid stage vascular dementia. When she had forgotten to take LM for a few days we noticed quite a negative change in her memory and ability to understand/reason. It hasn't healed her, nor will it but I feel it is slowing progression of the disease. Supposedly it does help with blood circulation in the brain and rebuild dead neuro pathways. Whether that's true, i can't say, but it does help clear her mind for now.
I hope she is well man!
Wait - there are people without anxiety or depression?
Look to amino acid therapy before drug therapy
I don't have either unless I have a reason.
yes, its called being normal.
@@virgilkirschner5717 mushrooms aren't drugs. its food
Didn't know that
Nicolas, on this topic you could easily give us your personal opinion by buying a high end lions mane product and testing it out yourself.
As we know, science facts change over time the more we learn about a subject.
With your critical mind, you could do the world of youtube viewers a solid by giving us your own experience.
I personally learned about lion's mane a few years ago at the age of 60. I was going to school for truck drivering and decided to help myself in what ever way I could. I feel that it did help me retain information better.
So, that's my experience. I'm wondering what yours would be?
Be blessed. I hope you do try it for our sake and maybe it helps you too. No harm if it doesn't work for you.
While that might be fun, I don't think it serves much. Anytime I share my experience, I get a bunch of 'well yea, that's for you, just wait until you're X number of years old!" and the conversation devolves into nothingness. Plus, I'd rather not waste time doing N=1 experiments when I could be releasing content no one else is (multi-study analyses), because there are many people who do N=1 experiments. Plus, it's a science brand, so if I shifted too heavily into just doing self experimentation, it just isn't that informative. People expect me to cover rigorously powered and controlled studies.
Still, I have done a little here and there (self experimenting) and shared my results. I don't have any interest in lion's mane, though, so I would be wasting everyone's time. :)
@Physionic ok I get it.
For my experience with you. When I first started watching your videos, I thought you were using studies/papers to push your point of view. As I watched more of your videos I started to see that you were really trying to deliver facts to help others and not your point of view.
You definitely can't please everyone, and I've noticed that more and more on TH-cam.
I myself find you credible because you're not trying to sell something every 5 minutes.
There's a person named Dr. Mike and I like him because he gives science based advice plus he practices what he says. He has also admitted where the science has changed and he had to change what he stated in the past.
Yes, it's a shame that you aren't interested in lions mane. Obviously you are smart and young. It would have been interesting to see if you personally felt that your memory or thinking had improved.
I do think you have the time in service that most people would find your word credible. But definitely your talks should be on presenting meta data because that's the show in a nut shell.
As a man who checks out the studies that others quote and not just believe everything I hear. You have won me over for the most part.
I thank you for your time.
Leo from San Diego. ✌️
LM definitely work for mood and cognitive function if you have issues with these. Unfortunately it also lowers DHT. I felt that and also blood test confirmed drop of DHT about 25%. So if you don't want to lower it take appropriate counter measures.
I know some people want lower DHT because of hair loss, but I can tell you that lower DHT sucks in terms of quality of male energy.
Damn 25 percent is a lot for a mushroom wtff
My grandson developed sudden onset epilepsy and was put into medically induced comas twice in a few months. I persuaded him to try some LM and he's been taking it for 18 months. It's been a while but his "Male energy" seems to be returning.
@@GlasPthalocyanine good some peoples never return glad to hear that
@@Yiahi65 Yeah. I stopped for like a year with LM and DHT is back to normal.
@@nieczerwony
I'm not aware of any specific scientific research showing a DHT-inhibiting effect associated with ingesting LM, only anecdotal accounts. Reishi mushroom extract may lower DHT levels but yet it's shown to have aphrodisiac and testosterone boosting potential (in rat studies).
Good info, thanks. What is that funky baseline at the end?
I take Lion's Mane and only felt a significant difference the first few times I used it.
The processing definitely makes a difference. Some suppliers grind both the mycelium and the fruiting bodies, which is most likely less potent than the fruiting bodies alone. Also the elephant in the room... it's usually a dried powder. Imagine eating the actual mushroom. Given that the mechanism of action is not well documented (as of my current knowledge), there is no easy way to isolate nor properly prepare the compound(s) responsible for the proposed action. As you say, more research is needed. Thanks for reading my TED talk.
can lions mane be given to infants asking for a friend
It seems it would be difficult to test when the active chemical is the fungus is unknown. I may be wrong, but I have it in the back of my head that fungus in particular varies a lot in chemical make up due to environment. An example from the bacterial world is the one that makes botulism toxin. Root crops especially but other veg as well is covered in a species that makes one of the most potent toxins known, but we aren't dropping like flies because it doesn't produce the toxin except under exactly the right environmental conditions. Fungus, I think, could be even more picky since in the wild they tend to swap and trade chemicals with many species in the vicinity.. They are also interesting for having well over two sexes.
My guess is scientists would want to use a lab grown mushrooms for consistency but they may consistently lack the active ingredient(s). Unless the active ingredient is known and measurable?
Great! my sister gave me some but I don't notice a difference.
I actually heard about this "supplement" from people who claim it caused them terrible mental issues. They likened it to "post finasteride syndrome" - a cluster of neurological symptoms like fatigue, brain fog, anxiety, lack of drive, etc. All, they claim, stemming from this supplement.
The Stammet's stack combos Lion's Mane with magic mushrooms. Would be fascinating to hear your thoughts on that.
Assuming this study was performed in rest homes it may show that the staff improved the quality of the food patients received during the study as a result of being observed creating a false positive for Lions Mane, but a positive for less processed food.
Bought some for covid induced brain fog and it has actually helped rid of that, its pretty surprising and it took about 1-2 weeks to have effect
You are the goofiest, dad-jokiest nutritional genius on YT. I watch for the solid insights; stick around for the next groan-worthy pun. 👍🏼
Great choice of topic
The first person to consume bit made me laugh because I always think that too, Nic. 😅
I'd like to see your thoughts on Cistanche at some point.
I have a lot of issues. Including ptsd, and nephropathy. I have to take 12 separate pills in the morning to manage it all. BUT I have my meds in a pretty good place. I used to take the complex of all the nice shroom stuff. I honestly only saw a little bit of effects. But that was before my diagnoses and subsequent medication. it seems that WITH my meds, it actually makes a WOOOOOOORLD of difference. I have a bit of emotional blunting from my meds, and one of the main issues I have is decreased cognitive function. The combo of meds was helping with the cognitive function. But didn't help but do anything to stabilize my emotions. WITH the shrooms, I have a much fuller experience of the world. I can feel the real depth of emotion I really should have. Not to mention the immense boost I get from cognitive function.
I'm trying to put together a reliable stock of it and the other mushrooms to help me do even better. I honestly think it's pretty essential to MY set of issues. Thanks for doing this video!
how are you now darling?
I tried it for a week in capsules I made and it gave me bad headaches but it was stimulating I think. My dreams were a little more intense after a few days too. Like it was almost too intense of dreams were I would wake up. I think one week isn’t enough. But it wasn’t what I was hoping for.
how is it going?
From personal experience they increase short term memory by quite a bit.
Well, idk if it is all the things it is hyped to be but wow do you have lucid dreams when taking it. It’s worth the cost for the entertainment value of the dreams alone. It certainly does something.
Long covid and burnout has limited my brain function a lot, I'll be taking lions mane and see if it helps.
And the verdict is?
make sure you've gotten the ones made from the fruiting body.
Lions mane gave me insane anxiety and panic attacks. Went away when i stopped taking them
I just ordered it. It will arrive on 6/25/2024. I'm in my late 50s no real problems but I could be mentally sharper. If you want my results comment below. I will report after a month of taking Lions Mane.
how has it worked out for you?
@@AchyllesBr 3 months now. Brain fog has cleared. My mood is better. I will continue to take it. Bought it from tic tok. $35 for a year supply.
@@Biker65 Nice to know friend, thanks for answering
This is great - I’m interested in studying in related fields. I do have a question though. If researchers haven’t isolated what molecule etc actually inhibits or helps the brain - how could they know if what they were supplying was always fruitful? I guess the mushroom doesn’t have many parts to it like if you were dissecting a medicinal flower but do you think that would be a factor to whether the stats aren’t there? Although I’m aware it’s never just one reason or cause for stats to be effected by other aspects of a study.
Paul Stamets mentioned mycelium of lion's mane has a positive benefit for cognition but the fruiting body has none or negative neurological effects. I don't know what studies he did.
10:00 you forgot the link. BTW, I really enjoyed the video in every aspect.
Just fixed it. Thank you for mentioning it.
How much of the exotic, sexy reputation of mushrooms is due to the fact that a small handful of them are wickedly psychoactive, and another non-trivially sized group will kill you horrifically?
….maybe we’re just hoping if we eat just the right head of braided tooth, fungus hair, magical things will happen to us
I think it's helpful, been taking it for 5 years. My advice to optimize: select 100% fruiting body sourced in USA or Canada. When taking powdered, remove from capsule and add to very hot water and let stand for 5-10 minutes, then add tincture, then consume. Works about 20 times better than just popping pills.
nice video dude, i like ur style and humour. thanks for the good listen. Also ur videos work really well on 1.5 or 1.75 x speed because of the way you talk and scripted it, which is awesome
I decided to take lions mane supplement after 2 years of worsening numbness across half of my body (to which doctors had no answer to), and it immediately started going away. I take it around 4 months at a time occasionally
I used to be a memory researcher, and used MMSE a couple of times in older adults. That 1st study is an excellent example of using the right measurement for the right population. There was a ceiling effect right from the start. Younger p's are going to score 28, 29, 30 right of the bat, and there's nowhere to really go fron there. If the M is 29 or 29.5 then what exactly are you trying to show? MMSE was a ridiculous measure to use
When I had a really bad concussion the following changed from very slow improvement to very rapid, as soon as I started taking a teaspoon of Lions Maine powder each day (i.e. Lions Maine was the only variable that I changed):
- getting from 45 degrees lying back to where I could lie down on my back without a nauseous feeling of my head spinning ie so I could lie down and sleep without being propped up
- Lumosity cognitive game scores went from shockingly bad to exceptionally good
However once I had fully healed, it did not seem to make any noticeable difference to cognitive tests or otherwise.
I’m not sure it helps but I’d like to hope so! Let’s do more testing. Maybe, some company/university can fund more tests if it benefits them. I’ve been taking it for a few months for anxiety/depression and can’t really tell if it helps any but worth the shot. I’ll keep taking it since it might
…‘symptomatic for anxiety’?
What, pray tell, is asymptomatic anxiety ?
Today I added 100MG Niacin and 500MG Lion’s Mane to my microdose schedule to fully implement the Stamet stack and see if there are any notable benefits.
Do you think there is any new information between recent Lion’s Mane studies and niacin studies that could shed any new light here? Obviously we don’t know if there is an actual mechanism here or not. Just curious!
how has it worked friend?
Thank you thank you thank you honestly been waiting for someone to look into this stuff and finally not repeat the same thing at me claiming it's a miracle drugs all I want to know is exact facts and knowledge man I appreciate your work
I take lions mane supplements from oriveda which are formulated precisely to the standards done in the best clinical studies, it helps with neuroplasticity and neurogenesis.
I have grown these and never for health purposes. They have been called lobster mushrooms due to flavor. They are absolutely superlative when picked and cooked d fresh. Not so good if dried ones are rehydrated and cooked.
1 minute into the video and I already liked and subscribed.
lion’s mane might not be the secret to eternal life, but it’s absolutely delicious. Tastes vaguely like lobster to me. It’s really nice worked into a sauce with walnuts on a ribbony pasta
Recipe
Not even a minute into your video and I am lmao. Though it won't take away from a brilliant and informative piece. Thank you! 🙂🦁🍄
This shit is a game changer if you have social anxiety!! You can put your words together easier and have less anxiety.
this feels like your sinisterly building up the argument in favor just to punch it down into the ground like a dragonball z character.
I have a violent digestion reaction to lions mane. Opened the second $60 bottle and again experienced the same reaction. Haven’t touched either bottle since.
Post rona had me feeling like a lot of people reported- foggy. One study suggested most people who had had the rona had less matter and the weight of their brain lessened. I noticed I had lost some brain horsepower so to say before I learned about lion's mane. I started taking it to get back to where I was and I kept taking it after noticing the differences of on and off. They're slight now but noticeable. A family history of Alzheimers is a good reason to start.
Please do one on acetyl-l-carnitine. On strength, brain function, cancer and so on.
Oh, is that all? 😉
@@Physionic hahaha, lol. I meant acetyl-l-carnitines effect on that stuff. Sweetheart 🥰🤩