ฝัง
- เผยแพร่เมื่อ 7 พ.ย. 2018
- We need to change how we prescribe drugs, says physician Daniel Kraft: too often, medications are dosed incorrectly, cause toxic side effects or just don't work. In a talk and concept demo, Kraft shares his vision for a future of personalized medication, unveiling a prototype 3D printer that could design pills that adapt to our individual needs.
Check out more TED Talks: www.ted.com
The TED Talks channel features the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and more.
Follow TED on Twitter: / tedtalks
Like TED on Facebook: / ted
Subscribe to our channel: / ted - วิทยาศาสตร์และเทคโนโลยี
The title 3D printing is probably inappropriate since that machine is simply a more advanced dispenser.
I think it's pretty accurate
but buzz words. You need hip buzz words
Through a synergistic disruptor approach, this Pharmaceutica game changer has laid out a roadmap to capture the low-hanging fruit in today's medical market. Doing good like a boss with more 3D printing and augmented virtual reality than ever. You've got this! 🙄
But really, cool tech, lots on the horizon in the medical field. Let's hope we get to see a lot of it in our lifetime.
he printed the pill, so it is a 3d printer for pills at least
While this prototype isn't 3d printing, it wouldn't be strange to see a design where the micromeds are pressed into a tablet before releasing. Also, there's now an actual 3D printed pill that was approved by the FDA. (Spritam, an epilepsy pill, the 3D printing process allows for a pill that is less dense, making it dissolve faster in the case of an emergency)
There are a lot of people in the comments talking about living a healthy lifestyle to prevent needing meds. I wonder how healthy living prevents being born with a heart that is too big for your body or any other congenital heart defect like my mother, with type 1 diabetes like a best friend of mine, with immune system disorders or psychiatric conditions like Bipolar or Schizophrenia. There are things eating kale and running 10 miles can't cure. Medicine and science isn't the enemy. Big phrama is bad, yeah got it, but swinging back to the dark ages where we treat science like witchcraft and pseudo-science like the gospel isn't the way to go either.
I agree. Being born with a congenital birth defect, I need my prescribed medicines to survive. If I don't take them...I die (a slow, horrible death as the effects of not taking these meds takes over my body), simple as that. When I was a young adult, I rebelled against my meds and tried not taking them for a little while - this led me into a very dangerous place, health/life-wise - I risked my life. Lesson learnt, the very hard way.
Yes, I live as healthy a lifestyle as I can, to help prolong my life, and the quality of it, and this body & mind I live in, as long as I possibly can (of which, my lifespan will be shorter than average) - but, the fact is, these medicines are also prolonging/saving my life.
Hear hear! I can't think of a better way to put it.
Exactly!
Exactly some diseases are not cured with food. Sometimes they'recompletely independent.
I think the comment is for someone who have a good body since born and dont do Healthy life style. But i hope everyone doin well in yall life. good luck! ✨ Im sorry for my bad english
That was awesome! I hope this becomes actualized!
Pros and cons of this technology:
Pros: Has the potential to massively improve healthcare and save thousands of lives, as well as creating a generally healthier population.
Cons: You have to hand over massive amounts of your personal healthcare data to private companies, who may use your genetic data among other things for their own purposes.
Not sure what to choose. It´s a really difficult choice.
So what if they use it tho, it'll just contribute to better studies for future medications or enhancing the ones already released
What's up with you Americans and privacy ? Your obsession with privacy is a drawback to important technological progress.
I wonder how long practical, widespread use will take to be implemented.
I'm afraid it wouldn't work. We need special trials for combination like this. Vitamin D assimilation is better with fat substrates. Some drugs work better in the morning, other drags we should take in the evening. This idea looks so good and easy on paper, but medicine isn't as easy as we wish to be.
Simply mind-blowing. Still, we have to wait and see how it evolves.
Japan already have that machine that makes the right dosage for the right person... but still pharmacists should handle it since they know how a medicine works, people can’t just have medicine maker at home... and one thing, there are some substance or medicines that would react to each other.. the kind of idea has risks, so we can’t just mix different medicines or vitamins to one tablet or capsule.. hope that in the future, professionals are still helpful than a machine alone.
simply way to solve it is lock the machine and have it require doctors prescription to unload drugs doctors can have special accounts which they use to send prescription digitally to machines which are at patients home
@@Nanohamage would agree to that, but the pharmacists still needs to have control over the machine... it's not easy to display all medicine ingredients in one machine standing by at home without even a professional's handle, there are ingredients that have conditions for it to be stable, like temperature for example. There's even a lot of process to make one tablet, and a machine alone can't fulfil it without the professional's work. The making of tablets isn't just mixing powders and compress, there are still many process to activate a certain component for the med to be effective and safe to be taken.
I would agree for a dispensing machine that gives a whole packed med and needing a doctor's prescription, but not to personalising med, it's just too risky.
@@Nanohamage Actually drs lack of training when it comes to medications kills thousands every year, if you ever work in a hospital you would be surprised how often drs write up incorrect dosages to medications and nurses pick it up, mainly because nurses dispense the medications to the patient and if the Dr has stuffed up the nurse is actually liable if they give it not the Dr.
I would trust a pharmacist over a Dr any day for medication advice. G.P drs should be made to do much more study in the medication area.
@@jessyincoolbeanie I agree. As a pharmacist this printer is a very dangerous concept unless there is some sort of dispensing control. Likewise some medications cannot be administered at the same time so there will be limitations to making a 'single polypill" . Reasons such as variations in absorption kinetics and binding interactions between certain medications will be a huge limiting factor. For example bisphosphonates must be given alone and with water only, cannot combine with anything, same for bile acid sequestrants, thryoid medications, quinolone antibiotics, etc.)
What is the Japanese machine called?
Finally a really interesting talk on talk again 👍
thank you
Thanks Dr. Mario
Disruptive technology. But with this, security should be a priority. We don't want someone tampering with the printer and making an overdose capsule of blood thinners or similar.
Ah! Security in the tech industry. This wouldn't be the first time something like that happened. Your breaks on your car could be hijacked. Your pacemaker is not protected to intrusions. Your insulin pump is far from foolproof and can be forced to release its full cartridge remotely.
How far away is this from becoming a reality? Seeing my dad as a diabetic another health concerns and this two Ziploc bags full of pills I can’t help but think that he’s getting severely overmedicated and talking to a doctor about this is almost impossible very frustrating situation not looking forward to going through this health problem myself.
I am struggling between mpharm and pharmacology and drug discovery, Bsc,following my interest in making better, safer, if not best drug or cosmetics:zero or very minimum side effects,compounding drugs to one, what's the best for the future?
Awesome, so how would one print an LSD pill at home?
*You can now tailor a custom trip for every person, with this one revolutionary machine!!!*
Niceeeee :)
If you stick with hydro-carbons you can get schrooms and opium spliced, LSD requires other chemicals 😉
wow, very funny
not niga, not at all
Amazing new technology!
I love when a doctor tries to revolutionize pharmaceuticals, without even consulting a pharmacist
anyone know where i can find more information on this topic? tia
WOW , Wisdom ....... nice job .
So much psuedoscientists in the comments here..
Just took a look at his website (www.intellimedicine.com). No one on the board has background in drug design, clinical research or pharmacology... no wonder the idea of encapsulating microbeads of medicine in a capsule seems naive to me. I mean it’s a great concept, but practicality-wise... not really! Just think about pharmacokinetics, drug-drug interactions, pharmacodynamics... I think the main issue with polypharmacy is 1) prescribing cascade & 2) lack of pharmacogenomic study. So he was spot on with a few points.
Cascade
incredible
so how do i get the pervitin
Come Oooon!
Great Creation
Thank u all
I was just thinking today that I wish I wasn’t the one telling my doctor what antidepressants to give me. I want my doctor to be able to test my brain to figure out what exactly my body needs to be happy.
This is what I'm exactly thinking. I know my body more than my doctor so I should be able to 3d print my own antidepressants.
It's an interesting perspective and very futuristic and convenient; however, concerning also
that's an idea worth spreading, right there!
Great invention
Glad to see that Cameron from Ferris Bueller's Day Off has succeeded.
Finally someone says it!
Great idea. But it's hardly to be possible because any substances that you will take into your body should under the control by pharmacists. That's a regulation 👌
no 1 english learning show
This is a neat idea, but I see a lot of issues to be worked out, and a black market as well.
Yes!! All for it. As a person who has to take about 10 pills on a daily basis. Yes.
This is really the future ! :) This will be so much better.
The problem with compounded medications is meds are compounded without full knowledge or consent based on any Dr prescribing meds they see fit under the auspices of the advancement of medications and off label usage of medications. Case in point the use off antipsychotics to treat what often amounts to misdiagnosis and or medication trials. Let's speak of genomics you mentioned...there are meds that target genes meaning that you maybe targeted via your genes to your demise.
Your theories are great when posed in a pawsitive light how there is a dark side to medications and posing only one side of the sword still creates a lethal combination. Mandated medications are a reality...what protective measures shall be instituted to assure that we in fact are not becoming fodder for a dangerous and potentially lethal situation that in fact shall and does create a lethal dependence across the board regardless of wether it is pain meds or high blood pressure.
Safety issues are inherent in the practice of medicine world wide and until we address this with specificity I am less likely to surrender my life 4 someone else's potential misjudgment and human error.
What a wide stance
First!
Print me up some Quaaludes! They have not been made since the early 90s
Coming Soon to a Drug Dealer near you!!!! The Perfect Cocktail!!! Lol
Where would I get the filament/substrate to print my meds, perscribed by a doctor through a pharmacy? Great, I save the pharmaceutical company the money of having to turn their raw chemicals into pills which they will pass the savings on to themselves, AND I get the expense and hassle of buying and operating my own pill printer! I could buy a pill press and use a compounding pharmacy right now if I were dumb enough to want this.
So, what about the drug interaction? If we take the drugs together how can we be sure that a drug will not interact with another
wow
Abilify that high on the list? Wow
I cant believe im watching this. I was thinking of the same idea but in a vitamin form. Spooky
Placebo effect 🤔🤔🤔
“t b nk cells”????
Pharmacist 🙌😇
vai brasil.
Your doctor prescribes some lifesaving medications, you take
to your local pharmacy to have filled, there is no way for you to know if you
have been cheated with an outdated ineffective generic or a lower dosage, its
not like you have a home lab to first test them, so you ingest the medications
as prescribed by an highly educated doctor without expecting any errors, hoping
that the pharmacist like the prescribing physician is a trusted drug pusher,
not like one found on the street, has scruples,
is not blinded by pure profit, nice to take under consideration, hoping for the
best before dying…You now realize in trust we trust our all…including life, limbs
and pocket book contents too…
Where does the Pharmacist sit in this equation? They are the medication-experts. Prescribing by a physician would be unnecessary due to the algorithms being able to diagnose/prescribe more accurately. If anything, the doctor should diagnose and the pharmacist should mediate the dosing by these computers...perhaps from a centralized office.
Doctors dont like pharmacists they want to do everything themselves.
Cảm ơn rất nhiều, video nói về xu hướng rất hay. Sinh viên dược sĩ đại học 40 Trần Cung của trường cao đẳng dược Hà Nội hãy đón xem video này nhé
I am a pharmacy graduate from India and I want to build my future in foreign countries like USA Australia can anyone tell me that what should I do.... To do so ??
im not an expert but probably with school or by connections
I have been tormented over what I know. American medical school is a laughing stock. Fly my butt to Switzerland.
I take Biperiden as needed only not main medication
Size of the pill will increase by integrating the drugs in one pill?
If increased then there will be difficulty in swallowing
starting w nursing homes incase it doesnt work out .. i see what they did there
The potential for expediting suicide is my first concern, because those desperate enough will bypass any safeguards.
Your picture is hilarious!
1:35 Speaks about his own grandfather's death as if it's nothing?
Sprinkles
10:40 - Mom these sprinkles taste horrible. NO!
The only concern here is what about drug-drug interaction?
That’s awesome let’s stop talking about it and do it
Would never happen due to liability and the criminal factor
These is neat but how does this affect cost of pharmaceuticals in the future. The cost of prescription is a huge concerning factor in the United States and other parts of the world.
I’m impressed I hate taking meds I don’t need. This is definitely something that needs to be considered by doctors and the government since they persist on telling people what meds to take and can’t figure out how to handle the medical problems in this country.
Printer dealers
2
Why outsource to a 3D printer, when our body can naturally produce the hormones as when required. n
I really hope this is not the pharmacy of the future. This is just a better way to sell drugs: bringing the big pharma straight into your kitchen.
Maybe we try not to get sick first? We could easily avoid half of the modern sickness just by having a healthier lifestyle.
Half though. Still some outside stuff is needed
No thanks. Just being not connected is good for me.
Is this an advert? It sure sounds like one
What about drug interactions though? There are many drugs you can’t take together.
the software would stop you from taking anything that is bad together. Just enter it once, and nobody will ever make that mistake again
Software already does this in healthcare today. It prevents them from giving out medications based on allergies and medication conflicts based on prompts in the software. The same thing could be applied here.
As said you'd make sure the printer wouldn't create such combinations but I would also hope those drugs wouldn't be in the printer together. You could only have basic drugs in there at home anyway.
Isabelle Ngo that is right
@@javinpaoli Avoiding contraindicated medications doesn't work for many people in today's world. I'm elderly and on disability and must get my medications through the most inexpensive means, and drug prices vary widely between pharmacies. So I have to deal with my primary care provider and specialists (cardiologist, endocrinologist, nephrologist, urologist, etc.) and getting medications via Costco, mail order, my local pharmacy, Walmart, etc. Different systems; different software. For every medication change, I must force whichever provider I'm with at that appointment to review my entire current list of medications and doses and hope they know of any potential problems. A few trips to the emergency room and urgent care tells me this just doesn't work.
Screw the IoT though
Would be GREAT, if it wouldn’t cost a fortune.
pharm.ai med.ai
THANK YOU! I have been telling people for the last ~2 years that the next major generation of 3D printers will be used for personalized medications. I only ever get disbelief or ridicule in return.
Would this put pharmacists out of a job?
I can't imagine selling large quantities of APIs to the public is going to be smiled upon by the FDA and other global regulatory bodies. It's a nice idea but implementation and approval will be difficult.
As a pharmacy student, I don't even know where to begin with the problems this thing could cause and all the exceptions we would have to make.
My grandparents ate a normal Mediterranean/Spanish diet, the only thing they did was clove of garlic in the morning with hot water and empty stomach, small glass of red wine during lunch time, coffee, a tiny piece of pure black chocolate daily, pure real honey, herbs, extra virgin oil, stews and broths with spanish cured ham bones, and everything bought in REAL markets (with stands and so on) from the land, farms, sea to the table. They died of old age, never took pills, only when they were very old... Same with my friends' grandparents...
Your grandparents had great genes then, good for them!
Are printed teachers the future of school
3d print food.
existed for years. A lot of cake stores use them
Killer App, literally...
stop eating sugar and go for a run
If it was that easy, that you could simply put the moleculestogehter like LEGO bricks, then there would be no problem developing litterally anything in this world, but thats not the matter at the moment right?
Get a grip please, this is bullcrap ;)
Don't let your kids touch that device...
Can't change the dose and excipients, not FDA approved unfortunately otherwise the polypill would already be here through compounding pharmacies. Regulation reform will probably not allow this for decades to come, unfortunately.
It's only the things we do for JESUS that will survive the way of eternal life.
Sounds interesting and fun but maybe focus more on eliminating the need for pills before focusing on making it easier for people to get them?
ترجمو لنا I want translation of this to Arabia 🌚🌚🌚🌚🌚
Or write us the incoming speech no problem English 🌚🌚🌚
You Get Out What You Put In...eat smart and exercise to live a long, healthy life!
This isn't always the option for everyone.
That's nice and all but there is a lot of people who do need medication. I think this is great tech.
@@drazgul9403 I understand and am not against, just promoting a healthy lifestyle instead of just popping pills for a solution.
It’s not that simple for for many people. Many diseases arise NOT as a result of diet and exercise. Oh course good diet and exercise will help. But it’s not a cure-all.
@@11cylynt11 agree
jackie chan knows his medicine
.
"Automated compounding" - good luck.
2nd
To little information. I'm not buying anything!
Not really 3D printing this is basically the glorified version of that raspberry pi smart bartender.
I have 2 main medications lifetime Haldol and Seroquel and healthy diet eating fruits and vegetables drinking fresh vegefruit juices and i am very healthy and very functional. I am not diabetic and not high blood and not obese
3D printed coca! The end of doubt😎
JESUS told his disciples with man this is impossible but with God all things are possible.
This guy talks for 3 minutes and feels like 30