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Live UTI Free
Ireland
เข้าร่วมเมื่อ 21 มี.ค. 2020
Separating myth from fact around one of the most common global female health issues, recurrent UTI. We connect patients, clinicians and researchers around the topic of pelvic health.
DNA-Based Testing for Chronic UTI: Dr. Nick Parkinson
Can DNA sequencing detect organisms contained within a biofilm or intracellular bacterial community?
In part one of our interview with Dr. Nick Parkinson from Digital Microbiology, we answer the following questions:
● Is it always recommended that a vaginal swab test be conducted alongside a urine test, for female patients?
● Can PCR or NGS tests confirm the presence of biofilms, and is it important to know whether a biofilm is present?
● Are there particular organisms that you see most frequently in cases of recurrent or persistent UTI?
● Given organisms are always present in the urinary tract, how do we know if the organisms identified are causing symptoms?
● Is it possible for known pathogens to live in the bladder microbiome and not cause symptoms?
● Is it possible for ‘good bacteria’ to cause symptoms, and have you seen evidence of this in your research?
● Is there any benefit to testing in between UTI episodes, when symptoms are not present?
● Have you done any testing on probiotics themselves, to see whether they contain what is listed on the label?
More information about Digital Microbiology by SBL: liveutifree.com/uti-test-kit/
How to order a UTI test kit from Digital Microbiology by SBL: www.digital-microbiology.com/
Watch our interview about different types of UTI testing available: th-cam.com/video/0TBxnYPhGLw/w-d-xo.html
About Nick Parkinson, PhD:
Nick helped drive and develop the Digital Microbiology programme from its inception in 2018 as a direct response to his experience of NHS management of recurrent UTIs suffered by one of his family. He joined SBL in 2008 from Oxford University where he was a senior post-doc researching Spinal Muscular Atrophy. Previously he held post-doc positions researching dementia genetics at the Institute of Neurology, London, and deafness genetics at both the MRC Mammalian Genetic Unit, Harwell and the University of Washington, Seattle, USA. Nick gained his PhD in molecular genetics in 1998 at the University College and Royal Free Medical School, London and BSc degree in Genetics & Zoology at Leeds University. He’s lukewarm about football, loves golf and is a committed McLaren F1 fan.
About Live UTI Free
Live UTI Free is a patient advocacy and research organization. We do not endorse specific treatment approaches, clinicians or diagnostics methods. The content of this video does not provide medical advice. It is intended for informational purposes only. The medical and/or nutritional information is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen. liveutifree.com/
Post-production: Melissa Wairimu kreativlee_
In part one of our interview with Dr. Nick Parkinson from Digital Microbiology, we answer the following questions:
● Is it always recommended that a vaginal swab test be conducted alongside a urine test, for female patients?
● Can PCR or NGS tests confirm the presence of biofilms, and is it important to know whether a biofilm is present?
● Are there particular organisms that you see most frequently in cases of recurrent or persistent UTI?
● Given organisms are always present in the urinary tract, how do we know if the organisms identified are causing symptoms?
● Is it possible for known pathogens to live in the bladder microbiome and not cause symptoms?
● Is it possible for ‘good bacteria’ to cause symptoms, and have you seen evidence of this in your research?
● Is there any benefit to testing in between UTI episodes, when symptoms are not present?
● Have you done any testing on probiotics themselves, to see whether they contain what is listed on the label?
More information about Digital Microbiology by SBL: liveutifree.com/uti-test-kit/
How to order a UTI test kit from Digital Microbiology by SBL: www.digital-microbiology.com/
Watch our interview about different types of UTI testing available: th-cam.com/video/0TBxnYPhGLw/w-d-xo.html
About Nick Parkinson, PhD:
Nick helped drive and develop the Digital Microbiology programme from its inception in 2018 as a direct response to his experience of NHS management of recurrent UTIs suffered by one of his family. He joined SBL in 2008 from Oxford University where he was a senior post-doc researching Spinal Muscular Atrophy. Previously he held post-doc positions researching dementia genetics at the Institute of Neurology, London, and deafness genetics at both the MRC Mammalian Genetic Unit, Harwell and the University of Washington, Seattle, USA. Nick gained his PhD in molecular genetics in 1998 at the University College and Royal Free Medical School, London and BSc degree in Genetics & Zoology at Leeds University. He’s lukewarm about football, loves golf and is a committed McLaren F1 fan.
About Live UTI Free
Live UTI Free is a patient advocacy and research organization. We do not endorse specific treatment approaches, clinicians or diagnostics methods. The content of this video does not provide medical advice. It is intended for informational purposes only. The medical and/or nutritional information is not a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen. liveutifree.com/
Post-production: Melissa Wairimu kreativlee_
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Barriers care homes face recognising UTIs
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Literature highlights how carers are key in contacting doctors in regard to the health of the residents. However, carers aren't trained in the signs or symptoms of UTI. Overall, research confirms the need for carers to have knowledge in UTIs, which can be achieved through additional training. What do you think is important for carers to know about UTIs? Let us know in the comments. #urinarytrac...
Background and teaser for upcoming barriers and facilitators interview study
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What are your experiences with healthcare and patient-doctor communication for recurrent and chronic UTI? Whilst some factors can improve UTI healthcare experiences, such as advocacy, empowerment, and awareness, we hear from many about the barriers that can stand in the way. To make change, it's important to understand and address the factors that contribute to good experiences and that hinder ...
What is menopause?
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Did you know that menopausal symptoms are associated with biological, psychological and social factors? Menopause is a natural biological process, in which the menstrual cycle stops due to hormone changes. The transition process is known as peri-menopause, and menopause is defined as when a menstrual period is absent for 12 consecutive months. How are UTIs related to menopause? Find out in my n...
Community Stories Sarah
มุมมอง 10814 วันที่ผ่านมา
A multi-faceted approach helped @sarahamackie recover from recurrent UTI. After experiencing monthly UTIs over an 18 month period, a combination of long term treatment for infection and pelvic floor physical therapy has helped Sarah become symptom free. You can read Sarah's full story on her website - find the link in our profile. Do you have a UTI story to share? It's so important that we shar...
The complexity of causes of UTI infections 1
มุมมอง 20614 วันที่ผ่านมา
It's important to understand what may be causing your urinary tract infection, as this informs treatment decisions, and can provide valuable information for ongoing management. However, causation is a complicated topic. Over on our website, we have an article which goes into this topic in further detail ➡ liveutifree.com/what-causes-a-urinary-tract-infection/ #liveutifree #womenshealth #bladder...
Have you ever heard of, or perhaps used, a vaccine for preventing recurrent UTIs?
มุมมอง 23521 วันที่ผ่านมา
Have you ever heard of, or perhaps used, a vaccine for preventing recurrent UTIs? Uromune, a spray-based vaccine administered under the tongue, was developed to increase immunity against certain UTI-causing bacteria. Previous research has demonstrated promising results for the vaccine, showing a reduction in recurrent UTI episodes and an increase in the UTI-free rate compared with individuals u...
Antibiotic Resistance and UTI Treatment: Dr. Nicholas Sanford
มุมมอง 99921 วันที่ผ่านมา
Can you treat a UTI if the organisms are antibiotic resistant? In part two of our interview with Dr. Nicholas Sanford, we answer the following questions: ● What is the difference between detecting antibiotic resistance genes and conducting antibiotic susceptibility testing? ● Do MicroGenDX test results indicate which organisms are considered to be pathogens vs. those that are considered benefic...
IBS and UTI link
มุมมอง 14728 วันที่ผ่านมา
Are irritable bowel syndrome (IBS) and UTIs connected? Research has found that despite individuals with IBS displaying more lower urinary tract symptoms, there is no added risk of developing UTIs. This doesn't mean that the symptoms can't be connected for some, and it's important to investigate a root cause. IBS and UTI may share symptoms as well as onset triggers. Shared symptoms include urgen...
UTI Testing and Urine Sample Collection: Dr. Nicholas Sanford
มุมมอง 1Kหลายเดือนก่อน
Can you have a UTI even if your standard urine culture is negative? In part one of our interview with Dr. Nicholas Sanford, we answer the following questions: ● Why does standard urine culture miss many infections? ● What is the difference between PCR and NGS testing for UTI? ● Can NGS (next generation sequencing) test detect biofilms? ● How do you know when to do UTI testing vs. STI testing? ●...
Management of UTIs
มุมมอง 106หลายเดือนก่อน
Views from carers: Management of UTI in care homes Research describes UTI as over-diagnosed and over-treated in care facilities, yet we also know that UTI is often missed or misdiagnosed. Care home staff feel they have to be creative in order to ensure proper hydration, even putting hot chocolate in porridge. There may be possible areas for improvement in management of hydration in care facilit...
What is IBS
มุมมอง 93หลายเดือนก่อน
Did you know that around 15% of the population experience symptoms diagnosed as irritable bowel syndrome, or IBS? IBS is a term used to describe a set of symptoms, rather than describe a cause. It's a biopsychosocial condition, which means the symptoms may have a biological, psychological and/or social cause. Symptoms that may lead to a diagnosis of IBS include abdominal pain, bloating, stomach...
Live UTI Free Community Stories - Jacq
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Live UTI Free Community Stories - Jacq
What are the most commonly reported symptoms of UTI?
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What are the most commonly reported symptoms of UTI?
PCR Testing and Antibiotics to Treat Recurrent UTI - Elizabeth Kavaler, MD
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PCR Testing and Antibiotics to Treat Recurrent UTI - Elizabeth Kavaler, MD
UTI and Hormones, Pre-menopause: Dr. Hlavinka's Insights
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UTI and Hormones, Pre-menopause: Dr. Hlavinka's Insights
The Influence of Bacteria in the Urinary Tract - Mary Cotter
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The Influence of Bacteria in the Urinary Tract - Mary Cotter
Why Accurate Diagnosis is Crucial - Roscoe S. Nelson, MD
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Why Accurate Diagnosis is Crucial - Roscoe S. Nelson, MD
thank you
The vaginal bacteria Gardnerella vaginalis triggers E. coli already hiding in the bladder
Can I use these tests if I am in the US
Yes you can I do Microgen all the time
I have anxiety.Now I am experiencing uti symtoms? what to do?
Sadly these solutions dont seem to be available in Europe😢
Can you give any advice for children 5 years old?
How do you diagnose an embedded infection?
How may I get connected to speak with Dr. Kavaler? I would like to discuss our lab's methodology that is a hybrid PCR plus Culture test, which is used to confirm viability of organisms, detect additional pathogens not targeted for on PCR and provide patient specific antibiotic sensitivity results. I would really like to have this discussion with her if possible? Thanks so much, I thoroughly enjoyed this video.
Do symptoms always mean an infection that needs antibiotics? 2 cultures of proteus positive. What about when there has been the one dose of Fosfomycin and symptoms lightened but never went away then 1 moth and a half later a 2 x’s a day for 5 days of Cefuroxime taken and again symptoms lightened but didn’t clear up and ultimately returned to very uncomfortable level?
Excellent information, thank you.
By doing what???
Where is this doctor located?
Thanks for your knowledge. Very interesting information. Common Symptoms happen to seniors 🧓 in our 60s.😮😢. Chiropractor adjustment to the low back NERVES. CAFFEINE seems to cause uti . Blocked nerves. Correct???
Why are people diagnosed with uti when the urine has no blood or leukocytes? Is the growth of urine culture alone good enough to diagnose uti, such as estereccocus?
Doctor I’ve been having symptoms for 6 weeks now I’m on my 4th antibiotic. Last week my urologist performed a PCR report that showed a moderate level of e-coli, low levels of ureaplasma and another bacteria. I’m in so much pain. Any recommendations?
The experts we interview aren't able to respond to comments, but you are welcome to send us an email and let us know where you're based so we can share relevant resources: liveutifree.com/contact
Dr. Kavaler. Thank you for this video. I’ve been dealing with a UTI for 6 weeks now, mostly due to the fact I kept getting false negatives. Any recommendations for treating a stubborn UTI? Seems I have three different bacteria causing the symptoms.
The experts we interview aren't able to respond to comments, but you are welcome to send us an email and let us know where you're based so we can share relevant resources: liveutifree.com/contact
This doctor is amazing. I live in Atlanta, GA and wish I could go see him. Do you have any doctors in the Atlanta area that treat cUTI?
There are so many of us that need help here.
Can you please send us an email so we can share relevant resources and links: liveutifree.com/contact
Please can you interview Marnie Simpson again and update us! Thank you
Did you see our post-fulguration update interview with Marnie? th-cam.com/video/lrGrwyFnnIs/w-d-xo.html
Hi Doctor, what would you use to treat ureaplasma? I was given 14 days doxy and 1.5g Azithromycin
The experts we interview aren't able to respond to comments, but you are welcome to send us an email and let us know where you're based so we can share relevant resources: liveutifree.com/contact
Do you think vitamin d3 has to be taken with k2?
The experts we interview aren't able to respond to comments, but you are welcome to send us an email and let us know where you're based so we can share relevant resources: liveutifree.com/contact
This is very informative!
I have had 3 to 4 UTIs (all e-coli)every year for the past 3 years. I have tried all over-the-counter aids. Still get them. I am now resistant to Nitrofurantoin after 3 weeks on it and still have the infection. Just put me on Cipro and I'm a bit nervous. Complete hysterectomy over 20 years ago and take Estradiol and also use Estrogen cream. My husband died 3 years ago so there is no sex. I'm at my wit's end as I am the only caretaker for my 91-year-old mother and cannot keep getting ill. I worry that I'll become resistant to more antibiotics or have to deal with side effects as I've been prescribed so much. Any recommendations would be greatly appreciated.
Sorry to hear you're experiencing that. You're welcome to send us an email and let us know where you're based, so we can share relevant information: liveutifree.com/contact
My anxiety is so so bad. I feel like I can’t control it. Could this be the culprit? Will it pass? Please tell me I’m not alone. 😢
A lot of people in our community report anxiety associated with UTI, so you're not alone in that.
Glad to see you're allowing comments (at least on this video.) Some may be useful, some may not be, but only by talking with each other about this condition can we band together and ask that protocols be changed. As the doctor says, we each think we're the only one with the experience because, without social media, there's no way to hear each other's stories.
Vaccine
Thanks live UTI free for the hug effort you are doing I have questions Is the PCR test available outside USA or Europe?
We aren't aware of whether Dr. Kavaler provides testing for other regions - you could reach out to ask. There are tests available elsewhere, and we have shared some of them here: liveutifree.com/2024-enhanced-diagnostics-directory/
My Doctor- urologist and Infectious disease doctor only does PCR-DNA TEST ON ME!!! My deadly bacteria doesn't even show up in a Regular Culture unless I'm near the precipice sadly 😪
How can I contact Dr Mandy
You can find the information Dr Mandy provided in the video description. You can contact her via LinkedIn or her social media profiles.
Madam... Can entamoeba histoyltica parasite cause... Uti infection like i.e cystisis?
The experts we interview aren't able to respond to comments, but you are welcome to send us an email and let us know where you're based so we can share relevant resources: liveutifree.com/contact
Greetings A male Ive got am uti 2016 from my partner(staph epidermidis-without simptoms on the blader just on prostate).On the start been on antibiotics.Gentamicin becme ressistant.Then ciprofloxacin.The lab results were negative after that and the urologyst told me i should not take antibiotics anymore or nobody could help me.Since then ive been on Green's.But the simptoms got worse in a way they irritating my prostate.Since that 8 years i just ejakulated normaly once.... when i was using a germany product cystinol akut(all the other times my sperm is like blocked to go outside and its really nerve wrecking),But the bacteria also got ressistant to that straight away,also to piptamin,nitrofurantion,even origano and some herb teas.Tried almost everything,and every tip and advice is welcome. Ps.Now ive been adviced to ureaplasma and mycoplasma exams
Thanks for sharing your experience. If you'd like to email us and let us know where you are based, we can share any relevant resources we have: liveutifree.com/contact
I found using a little Silicone lube just over the urethra after showering and definitely before sex, helps keep the bacteria out.
Thanks for sharing what has helped!
UTIS SUCK Thank you for the biofilm education and the bladder
Interesting information. Thanks 😊
Powdered D-mannose (2g or more per day), Serrapeptase (loosen biofilms). Also consider Ayurvedic treatments such as Utracon. Got rid of my chronic 3 yr UTI gently == no antibiotics. The urology field is making mountains out of molehills, unfortunately.
I've tried D-mannose, Vitamin C, and probiotics and nothing works. I've not heard of serrapeptase and Utracon is not in the US (that I can find.). I need something to help. I have 3 or 4 a year and am getting antibiotic-resistant.
@@PreciousMe Yup same here. Nothing seems to help. Also using vaginal estrogen, Hiprex, Vitamin C. I get them every 2-3 months. Working with an Ayurvedic doc and waiting for some test results so she can help.
My urine has smelled super foul for almost a year like Ive never experienced. Sometimes test positive for ecoli, sometimes not. Been on several rounds of different antibiotics. Saw 2 infectious disease drs incl Yale, also urogyns, emergency dept, imaging, bloodwork etc and still dont know whats wrong. Inflammatory bladder or IC is what they say. But I had IC dx years ago and the smell was not like this. Also a lot of urethra pain and painful bladder pressure. Please if you have any info I dont have lmk thx!
Can you please send us an email and let us know where you're based? We'll share any relevant resources we have: liveutifree.com/contact
I m diagnosed with interstitial Cystit with no infection or bacteria sign they even did a cystoscopie with biopsy nothing came out of its negative. I’m miserable it’s been years I don’t know what to do anymore i leave in France but I can travel . I just want this to stop .
Can you please send us an email and let us know where you're based? We'll share any relevant resources we have: liveutifree.com/contact
I have the same, can I ask did it start with a uti
My wife and I appreciate you Dr. Mandy! You’ve changed Mica’s life .
Thank you Matt! It’s been an honor getting to know you both ❤️
I did a evidence based video for those who want to know some of the science which you can see has several pages of references as well for those interested. I can assure you everything I discuss is evidence based. You can visit that video named the Root Cause of IC.
Why did you disabled comments in the shorts video? 😢 it’s kind of hard to interact. where is the antimicrobials article you mention in the last short?
Thanks for getting in touch. I have enabled the comments and here is the article that Dr. Mandy discusses: www.sciencedirect.com/science/article/pii/S2211124721013231
I have had a chronic uti for 18 years and I'm fed of clueless urologists and being fobbed of I don't know why chronic utis don't seem to be taken seriously when they should be this condition has killed my life and I don't know if I will be pain free ever again it's horrible being in deep agonising pain everyday for 18 years it's horrific very hard in the uk to get treatment and be taken seriously in the uk
So sorry to hear you're experiencing this - you're not alone. We hear so many similar stories. We can share information about UK specialists if you send us an email: liveutifree.com/contact.
She's really behind on the science of embedded uti's. Sounds like thousands of dollars for tests that have little to nothing to do with persistent uti.
She’s not behind in anything. Because of her thorough testing my wife was able to discover serious root issues that our other doctors had completely missed. Dr. Mandy is a God send and anyone who doesn’t think so just hasn’t had the privilege of working with her yet. 👏👏
Thanks to Dr Mandy my IC is in remission and I haven’t gotten a UTI in a long time
She has her own vision and methodology and everything is science-based and makes sense. And it works for many of her patients, as you can see. I have seen urologists Professors in embedded utis and they didnt help much in my case.
This woman is clueless and does not understand medical conditions. Doctor of what exactly? Not a medical doctor. Mitochondrial dysfunction is the cause of basically everything? Please direct us to the peer reviewed published journal articles on this. Another sad and appalling case of Dunning Krueger in someone suffering from unfounded over confidence.
Fantastic video. Very insightful. Finally … someone who understands UTI’s and IC. Thank you Dr. Mandy!
Thank you Dr. Mandy’s husband for this very unbiased comment.
@@dominikatanianis7132I am supportive of my wife and her business. If you would have followed her advice, perhaps you would have had significantly better results.
How can you haelp someone with Sjogrens Syndrome? There is a correlation with Sjogrens attacking the bladder lining
All autoimmune immune issues are inflammatory driven. Address the inflammation to quiet down the immune response !
The anti inflammatory effect of antibiotics are minimal. Even less than ibuprofen.
And it also destroys gut bacteria are responsible for keeping your immune system buzzing strong !
Notice you changed the topic. I commented on your incorrect fact. Not how they impact the gut
On the contrary, many of us who have both IBS and chronic/embedded UTI noticed a huge improvement in our gut health whilst on antibiotics. It's really disingenuous to state that antibiotics destroy gut health. Even though wellness blogger types like to throw that language around, the evidence (both scientific and anecdotal) does not support that claim. Also, Erin was talking about the anti-inflammatory effects of antibiotics, not gut health. The anti-inflammatory effects of antibiotics are greatly exaggerated. Many patients who have been on both antibiotics and very strong anti-inflammatory medications such as prednisone have not seen any improvement whatsoever on prednisone, but have seen improvement on antibiotics, suggesting that inflammation is not the issue so much as infection is.
Hi, do you receive patients from the UK?
yes we do
I found your interview very interesting! I’ve had IC , chronic UTI , OAB, for over 10 years, currently under Harley Street in Uk. I have always thought that there was an immune system ‘flaw’ and genetic component to my disease especially as my father had same problems. I’m sure you have a huge waiting list if you on have only 30 ish patients per year. How long does it take for your patients to get significantly better/cured even?
Wow your like me I'm under the lutts clinic london. Im trying to antibiotic bladder installations have got them yet though I have had chronic uti for 18 years wish I could find more people with this condition to find out how they have coped with there condition. As I think this illness is a nightmare being in excruciating pain all day everyday in the worst possible place it's life distroying
Do you receive patients from Germany by online treatment?
Madam... Can parasite... Entamoeba histoyltica cause... Uti infection i.e cystisis?
Any bacteria can cause infection when your immune system is compromised
@@ICHealer ok thanks a lot😊👍🏻
Can the immune system ever get rid of biofilms by itself, or are other agents such as biofilm disrupters and herbals always required?
@@orlahelendaly7905 biofilms are normal in the body and without them, you would not be alive. Your entire body consists of them. The issue is the types of bacteria that reside in them and how they invade and hijack your immune system. The immune system generally does "shed" the layer of the bladder periodically (check Dr. Malone's work), but if the contents in the urine are still hospitable for them survive, then they can recolonize. I believe an integrative approach is important.
What you’re saying could be very dangerous for people whose bacteria has become embedded inside the bladder wall aka “intracellular parasitisation of urothelium cells.” Read “Cystitis Unmasked”by James Malone-Lee.
culture tests ARE unreliable - the best way is EQUC testing !!!
Where is the link Dr mentioned at the End of the video that comes with 12 little videos of UTI prevention? Can you share? I didn't see it in the description?
Thanks for letting us know, we've just added it to the description, and it's here too: peedoc.com/bladder/
My problem is that I have an indwelling catheter and urologists rarely want to treat my infections saying that I’m likely colonized with them even though I’ve had symptoms of infection, I repeatedly have several bacterial infections over 100,000 the last time they gave me a dose of gentamicin but it’s two weeks later and it’s all coming back again
Thanks for sharing your experience. We'd love to do some content specific to catheter use and will aim to in the future. Melissa
I have polycistic kidney disease and a transplanted kidney I have constant urine infections I have had sepsis x2 please help
@@LiveUTIFree That would be great. At present my infectious disease physician has me on third week of Cefepime 1 gm for a pseudomonas infection that has repeatedly shown up. The catheter type I believe has created a lesion or wound inside my bladder because of the hard silicone tip in the medline catheter, when switched to all silicone Dover brand by Cardinal I believe that was lined with silver inside and outside, it seems so far to improve, but then again have been on iv antibiotics for almost three weeks. My autoimmune diseases make having repeated infections not only bothersome but dangerous to my health and threaten my life and have caused me to end up in a ventilator after my myasthenia gravies worsened and my diagram became too weak, so having physicians not treat infections become life threatening as much as any overuse of an antibiotic will. No good solution,
Lots of women are getting frequent UTI's after covid vaccine. My mom included, then she died from intestinal blood clot