Schizophrenia May Be an Autoimmune Condition
ฝัง
- เผยแพร่เมื่อ 22 มี.ค. 2020
- Schizophrenia affects 20 million people worldwide, and we don’t exactly know how it develops, or what causes it yet. However, some research has found that it might be an autoimmune condition.
Hosted by: Anthony Brown
----------
Support SciShow by becoming a patron on Patreon: / scishow
SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at www.scishowtangents.org
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Kevin Bealer, KatieMarie Magnone, D.A. Noe, Charles Southerland, Eric Jensen, Christopher R Boucher, Alex Hackman, Matt Curls, Adam Brainard, Scott Satovsky Jr, Sam Buck, Avi Yashchin, Ron Kakar, Chris Peters, Kevin Carpentier, Patrick D. Ashmore, Piya Shedden, Sam Lutfi, charles george, Greg
----------
Looking for SciShow elsewhere on the internet?
Facebook: / scishow
Twitter: / scishow
Tumblr: / scishow
Instagram: / thescishow
----------
Sources:
www.ncbi.nlm.nih.gov/pmc/arti...
www.who.int/news-room/fact-sh...
www.ncbi.nlm.nih.gov/pmc/arti...
www.nami.org/learn-more/menta...
www.nature.com/articles/mp201...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pubmed/2...
www.jhsph.edu/news/news-relea...
www.biologicalpsychiatryjourn...
www.ncbi.nlm.nih.gov/pubmed/2...
www.sciencedaily.com/releases...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pubmed/2...
www.ncbi.nlm.nih.gov/pmc/arti...
nyaspubs.onlinelibrary.wiley....
www.ncbi.nlm.nih.gov/pubmed/2...
www.ncbi.nlm.nih.gov/pubmed/2...
academic.oup.com/schizophreni...
www.psychiatryadvisor.com/hom...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
journals.plos.org/plosone/art...
www.healthline.com/health/syn...
faculty.sites.uci.edu/kimgree...
www.sciencedaily.com/releases...
journals.plos.org/plosbiology...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.ncbi.nlm.nih.gov/pmc/arti...
www.frontiersin.org/articles/...
Image Sources:
www.istockphoto.com/photo/pil...
www.istockphoto.com/vector/hu...
www.videoblocks.com/video/a-h...
www.istockphoto.com/photo/mar...
www.istockphoto.com/photo/int...
www.istockphoto.com/vector/nu...
www.istockphoto.com/photo/alb...
www.istockphoto.com/photo/thi...
www.istockphoto.com/photo/doc...
"We don't know what it is, and we don't know what's causing it."
Welcome to the world of mental health.
"...But you're definitely faking it / making it up for attention"
The followup response to every woman in the health care system.
Heck, I've been accused of faking having an autoimmune disease, and faking having mental illnesses, so now I can get accused of faking the connection between autoimmune disease AND mental illnesses! Fun stuff.
Yep. Sigh.
More like welcome to the symptoms of capitalism a.k.a. systemic exploitation heh
But we have pills for you
Western medicine at its finest
My family is filthy with autoimmune diseases. This could explain my sister's schitzophrenia. 😔
Living in northerly latitudes could do it as well. Lack of sunlight is a major risk factor for the development of autoimmune diseases
Kim in Alaska Same.
*Be a factor
@@mythreepants *Is a factor
VITAMIN D supplements?
Wow. My daughter is Schizoaffective, and she was recently diagnosed with an autoimmune disorder (we think it may be RA, we're going to the rheumatologist soon). This is eye opening.
@@sentientfetus3894 Stronger cells, eh? Suuuure.
@@sentientfetus3894 Where you getting this information? Do you know what autoimmunity means?
@Sentient Fetus
What makes no sense are your musings. Testosterone has nothing to do with your immune system, its a growth hormone that influences things like mood. Hormone imbalances cause issues like irritability or depression.
Autoimmunity isn't stronger or more cells, its your body's response to system. Ann autoimmune disorder means your body is prone to overreacting or misidentifying threats.
Yes, autism has been linked to autoimmune disorders as well, but an overactive one, that is to say things like allergies or sensitivities.
Sentient Fetus I read that vitamin d might help with symptoms. As people get less sun now and told the sun was bad...autism spiked. Vitamin D is a hormone that affects everything in the body
Is she having abdomen, lower and mid back pain(especially at the peak of inhaling for the mid back pain) too? Nausea and pain when hungry AND after eating? I'm also Schizoeffective and suffering Crohn's disease like symptoms the docs THOUGHT was rheumatoid arthritis too. It's important they diagnose it soon.
This is an incredible paradigm shift and gives me hope for so many disorders.
@ForestofTooMuchFood proof?
I feel the same about this
@@sas3dx it's true, I was the herbicide
The research has been mounting for over 20 years, a 2008 paper titled "From inflammation, to sickness, and depression" is a good read
Could it be from heavy metal toxicity? Mercury? Aluminium? Lack of nutrients and things like glycine?
Depression also is tied to inflammation in the brain. Maybe the neurodegeneration of various parts also link to brain inflammation
Makes sense
Multiple sclerosis is also highly linked with depression.
It makes sense. I believe most mental illnesses are at least in part caused by physiological illnesses.
@@KatGlos That's a connection that should go without saying- your brain is as much a part of your body as anything else. An illness in the body is an illness in the body. Brain cancer, depression, lung cancer- they're all equally physiological in origin.
A 2012 study of 6 common antidepressants act as an anti inflammatory on the microglia in the brain. The papers conclusion was that part of the efficacy of antidepressants was do to the anti inflammatory properties
I really like Anthony's clear and calm way of speaking.
You didn't cringe at "my-crog-lee-a"?
@@bdf2718 evidently didn't even notice. No one ever pronounces words the way I learned them in school (non native speaker) anyway, so meh?
@@grauekatze Hmmm, your username looks German, and Germans tend not to use classical Greek and Roman words to construct new words - we have a television but Germans have a Fernsehapparat. Even so, "micro" (from Greek, via Latin) is an SI prefix even Germans are familiar with. I don't know what "glia" is in German.
Second that, other SciShow hosts should take him as an example.
If you close your eyes, he kinda sounds like LeVar Burton
This is really fascinating!! As someone with multiple autoimmune conditions, I'm glad modern medicine is continuing to look into these factors. The immune system is complicated, and we barely understand how the human brain even works, so I wouldn't be surprised.
I have narcolepsy and a few recent studies have hypothesized that it may actually be an autoimmune condition. I caught H1N1 when I was 16yrs old and got extremely sick. Almost immediately afterwards, I suddenly developed GI symptoms. A few weeks and a few tests later, I was diagnosed with severe ulcerative colitis (a type of IBD similar to chrons disease). Nobody else in my family has any autoimmune conditions.
I've spent the last decade battling chronic illness and ended up having multiple major surgeries since the meds didn't work. My narcolepsy symptoms started in childhood but I wasn't diagnosed until a few years ago. My GI doctor is the one who first told me the theory that infections can trigger autoimmune conditions. Many systems in the body are connected in ways we don't fully understand!
That thing about narcolepsy as an autoimmune condition is super interesting! I think I have it too (in the process of getting diagnosed but it's expensive), would you be able to link those studies you mentioned?
Has any medication helped your narcolepsy?
@@gregorymalchuk272 Gregory Malchuk Yes! There's only a few medications approved to treat narcolepsy in the US: Stimulants such as Adderall and Modafinil are the most common. There's also Xyrem which helps us get more restful sleep and can lessen the severity of cataplexy. They've been pretty successful for me. However those only mask the symptoms - they don't fix the root of the problem. Recent studies have found low hypocretin (orexin) levels in the cerebral-spinal fluid of patients with narcolepsy. This is the same effect commonly seen in sleep deprived individuals, so the current understanding is that narcolepsy essentially causes chronic sleep deprivation. It's not available as a prescription yet, but I started taking supplemental hypocretin (nasal spray) about a month ago and have noticed pretty significant improvement. Hopefully it will become more widely available in the near future!
An Arab doctor named Fayed Muhammad improved the condition of autoimmune diseases by following a healthy diet
My doctor prescribed me mint oil pills and they worked nice for my intestines. I don't know if they'll do the same for you, but I had pain in my colon and it diminished since taking those.
This is an extremely important topic. I have some minor inflammatory issues currently affecting my skin, but my mother has schizophrenia. I always wondered in inflammation and immune issues played a part.
Scary
Skund it is a little scary. This is giving me the push I need to try addressing inflammation through diet. Anything to help lower my risk of developing.
@@skyla611 I wish you the best for your future!
Skund thanks!
There was this woman was diagnosed with schizophrenia but her doctor noticed something and it was a tiny inflammation in the brain. They were able to get rid of it and so she didn’t actually have “schizophrenia,” but at this point we don’t have a solid base of what schizophrenia actually is.
Now we need the US medical system to keep up. My friend has such a hard time getting consistent treatment ...
US medical system sucks. It works only for rich
My great-uncle had paranoid schizophrenia, and there are autoimmune diseases all over that side of my family-ulcerative colitis, lupus, etc.
Could it be from heavy metal toxicity? Mercury? Aluminium? Lack of nutrients and things like glycine?
Truly interesting!
This is very interesting to me. I had a client who has psoriasis in addition to schizophrenia and both seemed to flare up at the same time.
it is so sad that since 1950 there have been almost no advancements
Been dealing with memories of a person with this condition for about a week. Back in the 60's and 70's these things were considered character weaknesses and people were locked up and shunned like this lady I was trying to remember. Those who have this condition today can function in society with the meds and for most sufferers they get along adequately.
Sadly, when I did remember her name and her brothers name, they had both died within the last 2 years. The lady was never able to live on her own because of this condition. Maybe the insight in this video would have helped her!
I read an article in MIT's magazine saying that it's because microglia, which sort of "clean up" unused neurons and act like janitors for the brain, are "cleaning up" pathways in the brain that they shouldn't. They spoke of how the cause was likely genetic. And they spoke about how they couldn't just remove microglia because, besides the necessary cleaning not being performed, they secrete an enzyme that neuronal tissue can't function without. It was quite fascinating and has stuck with me for years. I had to have read it around 4 years ago.
This is a little bit of a weird story but hear me out. A little back knowledge to begin, my mother has her bachelors degree in biology, so she is educated to make an intelligent hypothesis. Continuing on, I had an ex bf whose step father suddenly had extreme behavior changes and schizophrenic like symptoms. Well their house was covered in house cat excretions and bodily fluids. One of the cats was really weird and my mom had the idea that the step fathers behavior changes were related to the state of the house because of toxoplasmosis, which is spread through cat feces. Toxoplasmosis can cause psychological symptoms. And that's how this relates to this video, that schizophrenic symptoms could be caused by an autoimmune response to some bacteria/infection or virus, or parasite.
How did the story end, did he recover? It's strange that they recognize schizophrenia is caused by inflamation and immediately think autoimmune disease instead of maybe brain parasite.
@@jihon3363 brain parasites hardly ever happen. Schizophrenia is common enough. I think you have brain parasites 😂
@@jihon3363 they didnt mention it in this video, but they believe its caused by autoimmune disorders because there have been many documented cases of long term psychiatric patients that only recovered after receiving treatment for lupus. the most famous and breakthrough case being that of april burrell. the washington post has a good article about her recovery if youre curious
Opioids can cause schizophrenia
Woooow! This is my first time checking in on this channel, and Im amazed by the character that is narrating this episode. Very well done and easy to follow!
Working nights in a mental health facility, I'll say the most common thing I see between patients with the traits associated with schizophrenia is sleep disruption, or lack of sleep. Once people have come in, it's not uncommon for them to have been up for over a week without ever even trying to sleep. We'll get people who insist that they need no more than 2 hours of sleep a day, and will do everything to fight going to sleep. This isn't 100%, but usually when people do not benefit from sleep while showing signs of schizophrenia they wind up having bipolar disorder. I believe we will not get a proper grasp of what's going on with patients who present symptoms of schizophrenia until we explore the correlation between it and sleep disruption. It could be autoimmune, it could be a development in utero, but all of it has something to do with sleep. We have patients who fit the schizoaffective guidelines who will be at our facility for days, weeks, even months, without ever sleeping more than 3 hours a day. We've had patients who have never slept more than a half hour a day. The brain is not designed to function like that. Every single one of them insist that they don't need to sleep.
I know someone who's schizoaffective and she sleeps normally, but is a light sleeper and has tendencies towards nightmares. I wonder if a sleep study would show anything...
I wonder if delusions during bipolar are also caused by a temporary increase in autoimmune activity.
I would think that the symptoms of schizophrenia would probably make a normal sleep cycle far harder to achieve than for the average population. I would wonder if it’s simply because other factors cause them not to sleep well (and then think they don’t need it) or if the root cause is some biological disturbance that makes them directly feel like they don’t need sleep.
It is more likely that the lack of sleep is a consequence of a perturbation of the systems in the brain. Sleep problems are quite in ME/CFS as well
Were they sexually abused before
Commenting for support
Interesting and worthwhile video. Be sure to download the supporting scientific papers linked with the video.
Anthony is quickly blossoming into one of the best hosts on this channel - very exciting! (Please give him the support in preproduction with pronouncing unfamiliar words).
I've always said micro-glia but strangely both Oxford and Merriam-Webster list it as he pronounced it. Now I'm wondering how that disconnect came about.
I have Bipolar Disorder, and I also have an autoimmune disorder, called Hashimoto's Disease, which I inherited from my mother, who also has postpartum depression and Seasonal Affective Disorder. Makes me wonder. . .
Growing up I used to worry I might develop schizophrenia. Instead I got multiple sclerosis, an auto-immune disease that attacks the brain and spine. I've had some minor hallucinations and delusions as a result and I often wondered how different it really was from schizophrenia. Apparently not much.
I’m curious do you remember your childhood if so how much minor trauma occurred before age of ten … how was relationship with parents and there parenting styles
@@amandah.2202 My parents were loving and attentive, but my mother's nature is the opposite of emotionally supportive so I didn't trust her or like physical contact from her by the age of 5. I spent a fair amount of time at a daycare facility run by my mother's friend, where I experienced some minor sexual traumas at the hands of boys in their early teens.
Did you live with mold in the house
@@eyeswideopen7777 No. That said, I'm starting to think stress and dietary habits (binge eating) along with a genetic predisposition are the cause of my problems.
@@GrimIkatsui yea I hear they need to eat healthy. Have you had it for a long time
Perfectly timed, too.
Wow! I’m blown away, this has put me on a good path, thank you 🌟💗🌟
That is just mind boggling.
No pun intended.
Thank you so much. This lifts a light in my disorder.
Umm, did you mean micro-glia (small glial cells) as opposed to microg-lia?
Agreed. My crow glee a (or al).
Other brain diseases look strikingly like autoimmune damage. Look at multiple sclerosis - where myelin sheaths surrounding axons degrade and die. the amyloid plaques of Alzheimer’s which are associated with the disease.
I'm sure their editing team is a bit understaffed right now or they would have caught it ;P
That's also what I was thinking lol
I thought the same thing, but google pronounced it like he did. However, my neuroscience professor pronounces it like micro-glia.
I think it might not just be schizophrenia though? My psychiatrist explained to me that inflammation is involved in all mental illnesses.
Either way, it's good news that the research is getting so broad. We need them to look in every nook and cranny.
😔😔😔😔 someone I love from childhood, years later is diagnosed with this problem... it breaks my heart to see what's happening to him 😔😔😔😔
I have childhood onset schizophrenia. I also have multiple personalities and an extremely high IQ. All is clinically diagnosed. My Schizophrenia showed signs before 3 years old.
If schizophrenia is brain disintegration, it is a direct conflict because of high IQ and extremely good memory.
Also, schizophrenia maybe heredity. My mother also had schizophrenia. Both my mother and I showed no signs of any autoimmune conditions.
As a child, abuse brought out my schizophrenia. Other wise it is mild.
I totally relate to that. Everything you said. I got diagnosed with schizoaffective. Every meds given to me gives unbearable side effects. Taking various supplements and going easy on autoimmune inducing foods helps a lot
@@EpinereinUrbextry niacin with vitamin c. Check out dr Abram hoffer
If true, this would change the current treatment paradigm of 1st and 2nd generation antipsychotics; that's awesome.
Edit: oof I just want to make a small suggestion for a correction: microglia is said like "My-Crow-Glee-Yuh
@@rbarajas86 ? He's usually pretty good.
I suspect he checked online. Oddly both Oxford and Merriam-Webster list it as he pronounced it. I tend to lean towards how it's commonly used in my experience, but it's also not technically wrong if two separate dictionaries list it as such. Guess it's just another "gif".
@@IanGrams Interesting. Folks in my field also pronounce it as M.Cruz suggested. I've never heard it any other way until this video.
Ian Grams when he said microglia like that it sounded to me like a more formal/fancy/“correct” way of saying it, like you said it is the dictionary pronunciation. personally I prefer the other ”micro-glia” pronunciation because it makes it more obvious for people with basic knowledge of glial cells (I’m in undergrad psych atm) to know what you’re talking about lol
@@jeffreym68 same here in the neuro courses I took. I'm rather curious how that disconnect between "proper" and common pronunciation came about now.
I took an hours long mental assessment for SSI. Needless to say when i received the papersss on this extremely long list ....included Schizophrenic along with OCD etc. After ignoring this for 20 years and all the stigma it entailed. I now finely decided to face that little demon. This really is an eye opener, and the most informative that i found since trying to cope. Thank you so much for this video.
Since autoimmune diseases are much more likely to developed in women I wonder why, if this is true, men and women have relatively equal rates of schizophrenia.
Or maybe men are less to be diagnosed bc they less likely shows symptoms (asymptomatic) or bc schizophrenia has a generic connection. I remember heart disease used thought of more male disease but females tend to show it differently.
There is evidence that a mother having an immune reaction to a cold or flu while pregnant can cause it as well. The birth months rates of those with schizophrenia show significant births in winter months respective of hemisphere.
Maybe this is why men say most women are crazy... It's just that the ones that are actually schizophrenic are not too much crazier to the men as any other woman they've met and so they don't realize there is something actually going on.
@Brook Heyes - I don't doubt that happens. However I believe when a man meets a schizophrenic woman once they will forever see emotional outbursts as a sign of what they see as crazy behavior. 1 bad egg ruins the omelet, as they say.
Some immune system genes are on the X chromosome. Women have XX, men have XY. It's thought to be why women tend to be healthier, and live longer, than men. But it also means they have increased risk of an immune system gene that lead to auto-immune diseases.
I hypothesize that schizophrenia isnt a single disease, but may be a group of diseases that result in similar symptoms, but with different causes. Which would help explain the rule of thirds.
This is fascinating!
This is fascinating!!
I have schizophrenia, working out really helps me ALOT!!!
How are you doing now hope you are happy
Sounds great, I have it too, what type of sports do you do?
It is hard to work out with no energy
extremely interesting video. ty
Dr. Georgia Ede has put this hypotheses to work doing a nutritional psychology
That’s really promising research for better treatment! :0
my sister was given vitamin d shots for deficiency, and it resolved her autoimmune food allergies. sunlight is good for my psoriasis. and vitamin d, from sunlight, can delay or reduce symptoms of MS. I hope scientists consider this as a possible compliment to nsaids and psych meds.
As a schizophrenic, I just like that one thing is said and I wish it would be acknowledged more. Schizophrenia treatments reduce symptoms it doesn't stop them. Its a treatment not a cure. I still hear and see things I know aren't there and I'm on a heavy medication regiment. People think the pills make them go away, but it, for me at least, just makes them more manageable.
if you don't mind have you ever had any suicidal thoughts do you also get suicidal thoughts about jumping off a high place 😔 please tell me truth i am suicidal 🙏 i am sorry if it hurts your feelings 😢
@@akshorts2115 I don't have personal suicidal feelings, but there are 2 distinct voices that do encourage me to hurt myself or even end myself. I want to help you if I can, suicidal thoughts are terrible and we all need help sometimes
@@krush454 hi thanks for your reply just wanted to ask u what would be your method of u have suicidal thoughts 🤔 just asking I am sorry if it's offensive to you
@@krush454 just wanted to ask u have u ever had suicidal thoughts about jumping off the building do u feel scared about it❓
We have a lot of autoimmune illness in my family, I've been diagnosed with one, and my mother has schizophrenia
There is a lot of evidence accumulating about 'inflammation' and any number of mental health disorders, but it shouldn't be forgotten that in the midst of our seeking infections and auto-antibodies, that chronic stress is a major cause of inflammation. In particular, living in an environment with a lot of expressed criticism and a loss of community are hugely influential in causing depression and schizophrenia. (Finally, I've witnessed many false dawns in the search for 'The' cause of mental illness, so I'll remain cautious in my optimism.)
both sides of my family have autoimmune diseases and a few of my family members (on both sides!) have schizophrenia as well, like me. also majority of us (esp those with schizo) have experienced major depression and trauma thru childhood. thank you for this video helping me understand more. i hope science can help us someday not suffer so much but i think many changes from society need to come with that as well. such as preventing trauma in the first place lol (predators, starvation, homelessness, lack of education, abuse cycles, etc. these have affected my family a lot)
I'm sorry for your loss I have schizophrenia too
Schizophrenia is caused by an ATP7B gene defect, which causes a toxic level of free copper in the brain. One of the fastest ways to lower free copper is the uric acid lowering drug, allopurinol. My brother's schizophrenia was gone in a month after taking allopurinol. He continues to take it to keep the free copper level normal and remain cured. He's gonna eventually convert over to taking 50 mg of zinc 3 times a day, one hour before meals, which prevents copper absorption from food. You can google "allopurinol for schizophrenia" and there are alot of articles talking about it. God Bless
Kudos for the one small step towards scientifically literate reporting at 2:32 ("Whether that's because inflammation causes schizophrenia or the other way around isn't clear") but you forgot the other very likely possibility that neither causes the other, but instead that both inflammation and schizophrenia are caused by an unidentified third factor.
I wish medical science would stop treating psyche like it isn't part of the large organ in our heads. If an auto-immune disease can cause my type 1 diabetes, psoriasis and lupus then why couldn't it do the same to the brain?
My grandfather exhibited schizophrenia-like behaviors after he got his leg amputated. He was fine before that but after he got discharged he slowly gotten worse. At first, I though it's because he was depressed because of the lost of his leg but after hearing him say that people are outside our window or after he was talking about war and other figment of his imagination (or maybe distorted memories), it dawned on me that he might have schizophrenia. We did not really took him to a specialist since there isn't one near us and we don't have the money to even go see a doctor much more for medication and therapy. Grandpa passed away 4 or 5 years after the amputation. Long story short, if this is true, this explains how he suddenly went from normal to his state in just a few months.
Came her for an answer. Left with laughter. Thanks for the laughs. God Bless.
My mom has severe RA and hashimotos disease. My dad has ulcerative colitis. And…. i’m the one with schizoaffective. I’ll definitely need to read some of the research. This is super interesting, thanks!
I want to hear more about this
Thank you for making this video for me cause I was told I was schizophrenic and I knew none of this information
I saw a video about some mental health problems possibly being autoimmune disorders a while ago, most doctors wouldnt consider that in a diagnosis
There are also statistics that say those with schizophrenia have a higher rate of epilepsy, and vice versa.
fascinating!
Is inflammation from allergies (for example hay fever) included in the inflammation that may cause schizophrenia? And are allergies an autoimmune disease?
I've had hyperthyroidism recently and four(two during the auto-immune condition) episodes of psychosis but have experienced severe trauma of various kinds and have underlying bipolar disorder suspected. This is a decent video though. Thank you for putting it out there.
Coeliac disease (an autoimmune disorder caused by gluten) is also linked to schizophrenia.
Great post, encourage people out there to checkout Coeliac, Gluten & schizophrenia online
I wonder if any food allergies can be related to this as some food allergies can cause long-term inflammation and what seems to be an autoimmune response.
i know some people w/ celiac disease display schizophrenia-like symptoms if they consume gluten :o so maybe????
This is so interesting. The idea that this may not even be a mental disorder is revolutionary for helping people with schizophrenia, but helping destigmatize the disorder as a whole. I really hope there’s new developments in this and that we’re closer to helping people who have, in my opinion, one of- if not the most crippling disorders.
Well, it's still a mental illness.
But there's definitely physical brain changes involved. It very well could be the immune system attacking certain neural structures.
...All mental illnesses involve structural, degenerative brain changes, in fact.
When ignorant people say "it's all in your head!" Well, yeah. And diabetes is all in your pancreas.😛 We people with mental illness issues have actual physical degenerative problems with our brains. We're not just whiners. Well, maybe a little whining. But it's a real physical illness.
Having a cause in the body doesn’t mean it isn’t a mental disorder. But it does demystify it in a way that can help others understand better.
Chris Frank Totally worded that wrong haha... I guess I had a blonde moment. But I’m not blonde so uh. Yeah no I’m just dumb. Thank you for correcting me! I appreciate you being nice about it!
Get the pitchforks ! Yeahhhhhh. Had a big caveman brain moment there... oops. Thanks for correcting me nicely! Think this whole social distancing has finally gotten to me lol. But, it’s so funny that in the year of our lord 2020 people still say “it’s all in your head.” Like, yeah no sh*t Karen, it’s a MENTAL disorder, but that doesn’t mean I can just walk my PTSD off. Ughhhhhh
Could it be from heavy metal toxicity? Mercury? Aluminium? Lack of nutrients and things like glycine?
So do they think the same of depression and GAD? Because I had an MRI for unrelated reasons and it showed my frontal lobe was very aged up. I've had depression and GAD my entire life, and I've read papers on how those conditions affect brain structure.
Amicable Enmity From personal experience, eating an antiflammatory diet has cut my anxiety and depression way down-particularly avoiding grains has had a huge effect.
Now is not the time to tell me I may have an autoimmune condition. (Seriously though, great video!)
I feel you man, I've suffered 15 years of psychotic breakdowns from my Schizoeffective disorder and it's been over a year that I've suffered and exhibited Crohns disease like symptoms(an inflammatory disease of the bowels). I get covid 19, I'm screwed. It'll be a tragic and pointless end to leave for my beloved partner and family.
Stay safe and take extra care.
I remember getting a bad infection when I was about three or four (I only remember bits and pieces--most of what I'm about to talk about is from my mom's recollection). I was in the emergency room once with a high fever and other symptoms, and they said it was a kidney infection, so I was sent home with antibiotics. Those didn't work, as evidenced by my later even higher fever, vomiting, etc. They eventually realized it was an infection in my toe that i got by ripping my toenail open on a stray piece of string on my parents' old comforter (I know--the chances of that happening).
Since then, I've dealt with progressively worsening mental health. I remember being five or six and consciously thinking that all of the TH-camrs I watched were robots, and not really believing that anyone I didn't personally know and have a connection with was a real person, at least on a subconscious level. The world hasn't felt real for nearly a decade. Paranoia and negative symptoms of schizophrenia started cropping up around 7th or 8th grade, which is also when my physical health started noticeably declining, developing orthostatic intolerance and chronic fatigue. Since then, my schizophrenia and the decline of my physical health have been progressing in tandem--getting noticeably worse in the colder months (extra inflammation and chronic pain from hEDS as the temperature drops, and the vast majority of my worst psychotic episodes happening at the turn of autumn and then again in the darkest and coldest parts of the year) before improving somewhat, but always on an overall downhill slide.
Quite honestly, it would make a good deal of sense if these things were connected in my case--I wonder what future research has to bring to the table!
Thank you for sharing, I pray for your healing. I’m reseating this for a family member. Look into orthomolecular medicine. With blood tests to see what vitamins you need you could find healing. I don’t know for sure, as my family member is not able to see there is a problem so helping has been hard.
@@annwalker8907 Unfortunately, extra vitamins won't help. The only noticeable deficiency I have is an iron deficiency, which I'm already taking supplements for--trust me, I've had plenty of blood tests, mostly administered by doctors who refused to believe it could be hEDS (a genetic disorder that causes collagen proteins to be folded incorrectly--collagen supplements don't help it in any fashion because it's just giving supplies to make collagen (any consumed collagen has to be broken down because it's too large of a molecule to be used as-is), which my body will make incorrectly regardless) because of its supposed (and likely false) "rarity".
Does this mean that people with allergies are more prone to develop schizophrenia ?
What about the roll of glial cells in the brain ?
*WE ARE WATCHING YOU ALL THE TIME*
Yes. Yes WE are. No idea who "WE" is, but you can be damn sure "WE" are watching.... I guess.
Explains why the Coimbra Protocol works so well with these.
I take a ton of meds and have remicade infusions every 6 weeks due to my UC (autoimmune disease) I wonder if similar treatment could help with schizophrenia then? I know in addition to my main illness it helps with my psoriasis and arthritis
Does your bowel disease come with a lot of fatigue and brain fog?
That could explain why some people show symptom decrease with dialysis.
Do an episode on bipolar too, later research has uncovered some really cool things. And it turns out bipolar is waaaaay more complicated then people thought.
I'd like to know more..
I remember going to hospital for infection before my symptoms/diagnosis weird.
What if you were born with it? My very first memory was at age 3 and I hallucinated a woman comforting me when I was crying and being ignored. She is still with me to this day. I have a very strong awareness of my schizophrenia and how my mind works, both against itself and for itself. I am currently 33 and do not have any immune diseases. I am diagnosed schizoaffective disorder - depressive type, and with ptsd due to the trauma of growing up with adults who refused to understand the fact that I was hallucinating and having delusions, and then slowly lost comprehensive and cognitive abilities as I got older. Correlation does not mean causation.
If schizophrenia is am autoimmune disease, I would expect to it occurring more often in women, which to my knowledge is not the case. I know that's not necessarily how the stats work, but even still, I would expect to see the same general pattern borne out.
UnashamedlyHentai - perhaps women with inflammation develop depression more than schizophrenia. Women seem to have a higher incidence of depression than men. Maybe hormones play a role in how the inflammation affects the brain.
@@bk2pla schizophrenia affects men and women equally.
With actual physical abnormalities in the brain shouldn’t schizophrenia be considered a neurological disease not a mental health disorder?
Fascinating
New research shows Schizophrenia might be a metabolic disorder. The keto diet seems to have a very positive effect, to the point of eliminating symptoms in some people, or at the very least being able to reduce medication with the help of their doctor. Don't reduce medication on your own. My grandmother, brother, son, and nephew all have or had Schizophrenia. Blessings and Grace to all those who suffer this horrible disease. 🙏 ❤
My dearest wish is to stop having hallucinations psychic draws and no voices that arent real as well not fearing that something has controll over my body. These are the worst symptoms that i can remember at the moment.
Is it lupus?
This is HUGE
How can you help my sister. She really needs help for her schizophrenia or we are gonna lose her???
Please look at correlation between Gluten & schizophrenia, if she cuts this out it may just help! There are a couple of stories online of recovery from this where patient were having hallucinations & Auditory episodes when they consume this toxic garbage! Wish her well!
Wow. I work in law enforcement, so I deal with folks dealing with this. This is huge. I really hope we can make some headway through this.
Is there any word on the worm studies about auto-immune disorders they had been doing? I have a coworker who has Crone's and when she's feeling bad, I always offer her some tasty tasty worms.
Worms!?
@@SuviTuuliAllan Yes worms! Not earthworms, but hook worms or pins worms. Maybe other types of parasitic worms. The hypothesis was they have an anti-inflammatory chemical to keep themselves from being eaten by the body, which can help people with auto-immune disorders. I saw something about the study on the BBC years and years ago. Never saw any serious follow up sadly. I had hoped it would work or generate new drugs.
It’s quite unfortunate that the field which deals with people with mental disorders the second most is law enforcement
@@Nosirrbro Amen to that.
One of my family member has similar symptoms she is talking continuously since last three days with herself and some Imaginary people.
We just started meds three days ago. How much it will take to stop her from talking 14 hours a day?
Try eliminating all inflammatory foods sugars cheese bread pasta and all junk food. Also try fasting .
That all sounds simple but helps tremendously.
Docs don't want to heal you just maintain you on meds that don't eliminate problems.
Good luck
Wishing you health.
Good luck
My tonsils they're abnormal since I was little but if I don't eat and work out the blood refreshes and it's gone
I recommend checking out Dr. Brooke Goldner. I'm beginning to try out her plant-based hyper-nutrition rapid recovery healing protocol, which incorporates a lot of omega-3 fats from things like chia and flax seeds as well as avocados and nutrients from a lot of cruciferous vegetables (minimal fruits - during the 6 week healing period). Also, she eliminates the foods that create the inflammation (animal products).
Check out connection between mold and autoimmune issues.
I want to see a video about vision snow please
I have Lupus, an autoimmune disorder. Should I be concerned?
Okay, so here's the thing. I'm 100% serious when I say this: I'm currently diagnosed with schizoeffective disorder. I'm honestly not sure what the difference is from regular schizophrenia but whatever, I don't really care at this point. The point is I've suspected for some time now that I'm not actually schizophrenic, but my medical records all mixed together out of context makes it seem that way. I've never had an autoimmune disease that I know of, but I DID do psychedelics a LOT when I was younger and constantly added sleep deprivation on top of it from a combination of the drugs and just general anxiety,depression, bi-polar1 and ptsd. I haven't had a real episode or gotten in trouble with the state since I stopped doing hard drugs (go figure) and I'm stuck on $500 a month social security with no ability to get and keep a job anywhere since I always magically get let go once it inevitably comes up in conversation, or soon after anyways. How do I get medical proof that I was just really high most of the times I was arrested and taken to the local state hospital and I that I don't normally hear voices unless I've been up for like 2 or 3 days with no sleep whatsoever (and even then it's mostly when I'm half asleep, almost like I'm starting to dream before I'm fully unconscious because I'm so mentally exhausted in that state)?-_-;
This is embarrassing to ask but I'd like to know, if anyone else has an answer. I already brought it up with one of my doctors that I see monthly and she was just kind of dismissive about it. She said she'd look into it and wrote something down, then never brought it up again. That was a few months ago. Shes pretty much the only doctor I see anymore so I don't really know where else to turn tbh. I can't support myself with this garbage paycheck and be able to HONESTLY tell everyone I talk to that nothing too serious is on my medical disorders list when it randomly comes up or more importantly, when I'm trying to get or keep a job.
Holy cow that's a long comment. Nobody is going to read this-_-;
@@businesschicken8699 I read it.
I'd maybe ask your question in the legal advice subreddit, or similar sub, rather than TH-cam comments. Even scishow's comments aren't really conducive to meaningful discussion.
I don't think you have to tell anyone about your medical disorders. I don't know where you are from but there are probably laws there to protect you (though idk if it helps if you can't afford a lawyer and whatnot -- get a public defender or something?). I do know that doctors aren't likely to listen to you when you have a diagnosis of a mental disorder (I mean, when do they ever? They ignore minorities, too). Aside from telling you to talk to some social worker (or an ombudsman?), I don't know how to help you. You probably can't afford to go to some fancy private clinic, can you? 500 a month is peanuts. Capitalism sucks. Oh btw maybe there is a non-profit organisation that can help you?
Oh wow, thanks guys:0
What if they take dmt.?
Could this same logic be applied to people with bipolar disorder? Is that why they have lowered immunity to disease?
It all boils down to the way words effect people
you guys should do a video on ASD next
I agree, though one episode might not do it justice since the spectrum is so incredibly wide, and the cases vary to an inordinate degree. And there's a whole tangent I could go on about how aspergers and low functioning autism really shouldn't be lumped together, but that's a whole can of worms I don't want to get into in a youtube comment section. I'd love to see some positive attention about it though, I'm sure the scishow people could do it justice and poke through a lot of the myths and misconceptions around the entire spectrum (for instance I happen to know a few very extroverted and social people on the spectrum, and some that actually really like working in fields that are very variable and adventurous, and even social! every single one of them is a very unique individual!).
"Structral brain differences" You can say that again, their holes of the center is huge, these are extreme brain damages! Strange thing is my parent has schizophrenia and I have an autoimmune condition but never had or have schizophrenia. And what do we do about the brain damages that are already there? We cant heal those..yet.
Going along with this theory, it could be implied that the gut plays a role in schizophrenia as well, as the gut is linked with both the brain and the immune system in ways that's still being looked into.
If someone can have leaky gut, it seems possible to have a leaky blood-brain barrier to, among other things.
Thankyou for the video.
All of what was said till 0:25 and yet, no news media reports on that.
I usually feal the best right before I get sick. Then the next day when I get sick I have rilly bad mental health. The day before I get sick I think that my bran is better because my immune system is fighting the sickness instead of my brain. I hope this is helpful
I wonder if this could apply to other mental health conditions as well?
@@sentientfetus3894 Why does autism spectrum disorder strike you as a likely candidate? I strikes me as one that probably isn't neurodegenerative at all actually. Since it's definitely present from birth (or at least a very early age, though diagnosis can't come until later since it's heavily tied to complex social behaviour). The DSM has historically grouped schizophrenia and ASD together a bit, even going so far as to make them mutually exclusive, something I have always been extremely hesitant of, but this confirms my critique more in my eyes. People with ASD aren't necessarily anti social in the broad way schizophrenics seem to be, and the lack of hallucinations and lack of required presence of damage to the brain is very telling too I'd say.
@@GLaDTheresCake the mutually exclusivity of autism and schizophrenia comes from them affecting different parts of the brain differently
Omg that does make sense
I mean it explains the steps down, they'll take over the years, getting worse shizophrenia symptoms by this
I swear, the next person who tries to tell me, "It's all in your head / have you tried thinking more positive / just be happier / just put in some effort," going to fricking GET IT. Shut up and be glad your immune system doesn't hate and attack you, GLADYS
My friend who was diagnosed with schizophrenia’s mom had lupus.
I don't know what it is but I like this presenter's style.