I have not seen a better explanation especially for the DNA sequencing. In other videos on youtube they dont explain much perfectly the fact, how dideoxynucleotides help show the letters when running trough gel. Thanks to your emphasis on the importance of lenght and so many varieties of where dideoxynucleotides can bind when the amount of DNA is huge, it helps to imagine how the nucleotides are gonna run trough the gel one by one until the whole order is read. Really good job!
I have been studying a-level biology for two years and these videos have helped me understand so much! Keep it up! University is going to be so much easier thanks to watching you!
Mr. Andersen thank you so much! You have no idea how much this has helped me and how well I understand things because of the way you teach them. Keep doing what you're doing!
Hey Paul, I would like to start from thanking you but again can't thank you enough. After seeing your videos (actually studying) I can say, my thurst for looking more is completed. I salute. Thanks...
Thank you, the working of PCR can now easily be understood, thanks to the simple method used to bring it across, brilliant!! I get a lot of help watching your videos, thanks again.
DNA Ligase is what combines broken DNA fragments. I would not say it is just "hydrogen bonding" as that only exists between the bases. The backbone must also be covalently bonded. Good video though.
+Sentient Yeah... The hydrogen bonding can only merge two complementary strands together into one double-helix. But it cannot join two helices together into a longer helix. There has to be something which will make the peptide bond between the 3' and 5' ends.
i'm just watching it, couse i have missed this guys. i used watch his video every day when i was in college. definitely brings memories. he is very good explainer.
I was skeptical when saw all the comparisons ( 'comparisons are odious') almost could not get thru...but.. you united main concepts pretty nicely. super happy. thanks.
"What if I had not taken LSD ever; would I have still invented PCR? I don't know. I doubt it. I seriously doubt it." - Kary Mullis, inventor of the polymerase chain reaction.
I enjoy watching Mr. Andersen's videos very much!. You're a true molecular biologist, and remind me of Alton Brown (from Food Channel) who is also excellent on explaining everything from science point of view.
thank you so much! you are extremely helpful! i enjoy watching your videos after my lessons and i honestly understand the material so much better! you are blessed!
Thank you so much! I love your videos! You are so smart and make it so easy. You are better than my professors. You explained it better than my professors in the master level! You should teach us!
This video was really helpful! It would be so good if you could do a video series for A level Biology and Chemistry with snippets of your own interesting comments and extra information- that would be great :)
You hope that's helpful????? That's way much more helpful than anything. We have two teachers who are really highly educated to teach these stuff. I tried my best to learn from them and I couldn't understand shit. You are a legendary teacher. The eat you explain and link various things and use all those examples. I hope everyone gets to learn from awesome teachers like you. Keep up the good work.
I totally understand what you mean. My second chemistry course was taught by a Ph D in Chemical Engineering; he could not grasp why learning the material was so difficult for his classes. The University's BEST chemistry professor only had an M.S. but he had many awards for his teaching skills. My college years in Chemistry coincided with the realization that just because someone has an advanced degree does not mean they can adequately explain it to anyone.
from my understanding, ligase seals the nicks along the axis of the double helix between nucleotides, due to the formation of okazaki fragments. Whereas H-bonds actually hold the two strands together, perpendicular to the axis of the double helix. Metaphorically, it might be misleading to think of both as "glue" especially in the context he was discussing, namely, applications of molecular biology. You need to open up the DNA to use it for practical applications such as PCR, so H-bonds are what you need to un-glue to achieve this. On the other hand, I don't think you would need to undo what ligase does b/c there's no practical utility in reproducing okazaki fragments. But don't take my word for it, i aint got no phd.
Nice video, BUT, on min 13:30 he says something wrong, "A is gonna be that little fragment" and points to the top of the gel electrophoresis run, when the smallest fragment would be on the bottom of the gel. though both fragments ended in A, they are very different in length
Thanks so much for your explanations, but I would like to know if you have a video of translation of RNA into ribosomes, for example the three steps of translation: initiation, elongation, and termination.
is it true that we only know a small portion of the full sequence? I heard there is 64 parts but only 24 that are active, if so why doesn't nature use the full sequence? it's almost like d.n.a is waiting to evolve...
The amount of knowledge this guy has is crazy: "He was riding his motorcycle one day and came up with this" like god dang Mr. Andersen is on another level
Your "real" students are literally the luckiest kids ever. Thank you!!!
SO TRUE!!!!
This channel is where I go to before a test
I assumed you were talking to me since I commented on it first.
nice
th-cam.com/video/H66MMTW8KNY/w-d-xo.html
Mr. Anderson, I'm really jealous of your biology students for having a great teacher like you. Thank you so much sir!
Finally a briskly paced video without 30min of useless introduction. Thank you!
I wish I had teachers like you for all subjects!
same
this video taught me more in 15 mins than I've learned in a month from lectures. thank you so much! the way you speak and explain things is perfect.
Dude. I have a test in an hour and I haven't studied so I'm binge watching your videos and you. Are. A. Godsend!!!
How did that go? Im in the same boat lmao
+Gwendolyn Penaco I somehow did one of the best in my class omg.. Thanks for asking and good luck!
@@WithASideOfFries don't suppose you remember the stuff 5 years on? Exam crisis over here 🤣
@@Liamalaing Same ahahaa I have an exam on Wednesday, can't focus, can't study but this video somehow has been able to catch my attention
@@larafernandes287 mines on Wednesday too, please help 😂
Our teacher doesn't teach he just shows us these videos
Relatable.
Exactly true
I have to watch this for homework :(
I love your teacher’s strategy 😜
Same
When someone can explain genetics in this simple manner, Someone REALLY understands genetics! Thank you, professor!
If it wasnt for your videos, I would have been screwed in my AP Bio class.
I wish you were my real teacher...
Got to admire the sheer effort he puts into his videos
I have not seen a better explanation especially for the DNA sequencing. In other videos on youtube they dont explain much perfectly the fact, how dideoxynucleotides help show the letters when running trough gel. Thanks to your emphasis on the importance of lenght and so many varieties of where dideoxynucleotides can bind when the amount of DNA is huge, it helps to imagine how the nucleotides are gonna run trough the gel one by one until the whole order is read. Really good job!
One of the most comprehensible biological videos I have ever seen! Terrific.
I have been studying a-level biology for two years and these videos have helped me understand so much!
Keep it up! University is going to be so much easier thanks to watching you!
Only reason I'm getting an A in my AP Bio class are your videos.Thank you so much!
Mr. Andersen thank you so much! You have no idea how much this has helped me and how well I understand things because of the way you teach them. Keep doing what you're doing!
Using this to help review before a high bio test and this is a LIFE SAVER
Moleculer biology was never been so easy. Thanks to you.
the way u make the things clear and more easy is just amazing
Hey Paul,
I would like to start from thanking you but again can't thank you enough. After seeing your videos (actually studying) I can say, my thurst for looking more is completed. I salute. Thanks...
Thank you, the working of PCR can now easily be understood, thanks to the simple method used to bring it across, brilliant!! I get a lot of help watching your videos, thanks again.
Your videos are saving my exam tomorrow. You have my subscription.
DNA Ligase is what combines broken DNA fragments. I would not say it is just "hydrogen bonding" as that only exists between the bases. The backbone must also be covalently bonded.
Good video though.
+I like robots yes im so confused
+Sentient Yeah... The hydrogen bonding can only merge two complementary strands together into one double-helix. But it cannot join two helices together into a longer helix. There has to be something which will make the peptide bond between the 3' and 5' ends.
He is talking about bond not enzyme right?
I absolutely love your analogy of the Pachinko machine and electrophoresis! Wonderfully explained! You're awesome, Mr Anderson! :D
i'm just watching it, couse i have missed this guys. i used watch his video every day when i was in college. definitely brings memories. he is very good explainer.
I think you just saved my microbiology lab grade!
You are a very helpful teacher, and at most times, even more helpful than my own teacher! Thank you a lot
No joke, about an hour or two of lecture in my class left me confused and then 15 minutes of this video made perfect sense
THANKYOU for explaining Polymerase Chain Reaction so clearly and nicely!!
Thank you so much for making my life a lot easier whilst studying for a test sick.. :) It would be so hard without you, you are a life saver!
I was skeptical when saw all the comparisons ( 'comparisons are odious') almost could not get thru...but.. you united main concepts pretty nicely. super happy. thanks.
MAN! You are such an amazing teacher!! WOW...seriously, just awesome. Thank you!!!
THIS VIDEO FREAKING SAVED MY LIFE, I FEEL LIKE I JUST FLEW AWAY AND FOUND THE ENLIGHTENMENT TYTY I CAN DIE IN PEACE NOW
Ready for my test tomorrow after watching your vids.
Incredibly helpful, thank you for being so logical and clear
Thank you..I have a test tomorrow and this clarified the information very well.
This channel has helped me through my biology course !
You're one the greatest teachers, looks like you have great passion. Keep doing it!! :)
"What if I had not taken LSD ever; would I have still invented PCR? I don't know. I doubt it. I seriously doubt it." - Kary Mullis, inventor of the polymerase chain reaction.
LOL
moral of story,"chill" is great for brain😨
Really?
I enjoy watching Mr. Andersen's videos very much!. You're a true molecular biologist, and remind me of Alton Brown (from Food Channel) who is also excellent on explaining everything from science point of view.
Forever No.1 TH-camr!!!!
You are amazing. You made this sound so simple. Subbed.
Your video made the topic make so much more sense, thanks so much!
you deserve the world Dr. Andersen
Thanks so much for your time and effort to make these videos to educate us!
You have a gift of simplifying the complex. Dear Lord this is good information!
YOU JUST SAVED MY GRADE THANK YOU
Thaaaaaaank you! It helps me a lot to get through my upcoming med school entrance test :")))))
Molecular biology is really hard to understand. Thank you dear sooooo muuuuch
Mannn Paul Anderson is just the best. I love these videos they're so helpful.
your teaching method is fabulous i realy learn from it. thanks a lot.
thank you so much! you are extremely helpful! i enjoy watching your videos after my lessons and i honestly understand the material so much better! you are blessed!
You hope its helpful? You are possibly the most helpful person on youtube!
Finally I found a great explanation! Thanks mate!
Really appreciate you taking the time to make these videos, it helped make the difficult easy, thaank youu!!!
Your analogies really helped me get my head around this, thank you!
Best teacher ever.
Thanks it's so much clearer for my exam after tomorrow :D
Thank you so much! I love your videos! You are so smart and make it so easy. You are better than my professors. You explained it better than my professors in the master level! You should teach us!
You are amazingly great! Thank you so much for your great videos!
Amazing video! It's very clear and helpful, thanks!
Thank you. You are very clear in your presentation and very informative. Your videos are very much appreciated!
This video was really helpful! It would be so good if you could do a video series for A level Biology and Chemistry with snippets of your own interesting comments and extra information- that would be great :)
You hope that's helpful?????
That's way much more helpful than anything. We have two teachers who are really highly educated to teach these stuff. I tried my best to learn from them and I couldn't understand shit.
You are a legendary teacher. The eat you explain and link various things and use all those examples. I hope everyone gets to learn from awesome teachers like you.
Keep up the good work.
I totally understand what you mean. My second chemistry course was taught by a Ph D in Chemical Engineering; he could not grasp why learning the material was so difficult for his classes. The University's BEST chemistry professor only had an M.S. but he had many awards for his teaching skills. My college years in Chemistry coincided with the realization that just because someone has an advanced degree does not mean they can adequately explain it to anyone.
you are my saviour . Thank you so much for the good explanation
Shouldn't you include DNA Ligase as the "glue" in addition to hydrogen bonding?
from my understanding, ligase seals the nicks along the axis of the double helix between nucleotides, due to the formation of okazaki fragments. Whereas H-bonds actually hold the two strands together, perpendicular to the axis of the double helix. Metaphorically, it might be misleading to think of both as "glue" especially in the context he was discussing, namely, applications of molecular biology. You need to open up the DNA to use it for practical applications such as PCR, so H-bonds are what you need to un-glue to achieve this. On the other hand, I don't think you would need to undo what ligase does b/c there's no practical utility in reproducing okazaki fragments. But don't take my word for it, i aint got no phd.
Best teacher! so simple and practical!
this guy is absolute lad when it comes to teaching
Thank you SO much! Hoping for a 5 tomorrow 😓
You're an awesome teacher seriously ! *applause*
Thank you for sharing! Your video provides a visual summary of this topic, for my Microbiology course that is online :)
Wow, this is a VERY helpful video! Thank you.
Nice video, BUT, on min 13:30 he says something wrong, "A is gonna be that little fragment" and points to the top of the gel electrophoresis run, when the smallest fragment would be on the bottom of the gel. though both fragments ended in A, they are very different in length
Awesome teaching! Thank you so much...You are a very good teacher I can see that😇 in your way of teaching....
im studying to the national ap bio exam tomorrow. thank you!
This video is so good and clear! Thanks a lot for such a great job!
thank you so much, sir. this makes so much more sense....
Pachinko, woo! Thank you so much for all of your videos (and your pachinko analogy, that really helped) :D
Thanks so much for your explanations, but I would like to know if you have a video of translation of RNA into ribosomes, for example the three steps of translation: initiation, elongation, and termination.
You get like because of the subtitles. Thx :)
Actually I'm Brazilian but your videos help me a lot. Thanks!
Amazing! The best biology teacher ever :'[ I got the acceptance to study bio but, Damon that , now i want to study molecular biology :(
You are a damn good teacher my friend. Thank you for freely sharing your knowledge!
Hey paul,
do you reckon you could do a video on biomechanics in sport?
ty
Thank you very much for making this video !!!
A-level biology exam tomorrow, thanks so much
Thank you so much mr. anderson
Anybody got a definition for biotechnology? 3-5 Sentences. Thanks
Thank you. Great explanation!
How many fragments can be form in a circular DNA?
I can't thank you enough!!! I LOVE your videos, they have helped me so much!!!
is it true that we only know a small portion of the full sequence? I heard there is 64 parts but only 24 that are active, if so why doesn't nature use the full sequence? it's almost like d.n.a is waiting to evolve...
best teacher in the world .. :)
fastest subscribe ive ever done
good explanation :)
Very good videos of you , SIR....
Love watching this instead of reading the book
The amount of knowledge this guy has is crazy: "He was riding his motorcycle one day and came up with this" like god dang Mr. Andersen is on another level
ur soo cool!!!no one can explain things better than you :) ur the best !(y)
Omg that was perfect!!!! Thank you a lot 🙏
super helpful. Thank you.