You did a great job, it's all crystal clear But I just wonder about the last topic, how do cell choose polyA site to be used if there are two of them , is it have something to do with any factors regulate by cell environment?
There are many RNA binding protein who does this alternative polyadenylation job. Check out this article for a reference www.frontiersin.org/articles/10.3389/fncel.2018.00518/full
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@@animatedbiologywitharpan When the mRNA is cut to add the Poly A tail, there is a short mRNA strand that is still attached to the DNA-Polymerase complex. Look at 3:02
@@eminemlandsteiner168 I believe that all following mRNA on from the RNA polymerase will be degraded because there will be no more 5' capping of this RNA. The RNA polymerase will understand not to continue transcription partially due to this and also due to the fact that there will now be more phosphorylation on the serine2 than the serine5 on the CTD :)
We just love ❤️ your videos, they are short and comprehensive at the same time even though we easily understand them.......thank you for such efforts.
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Yes, this was pretty much informative...keep uploading
Nice style of explanation.. I understood easily
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You did a great job, it's all crystal clear
But I just wonder about the last topic, how do cell choose polyA site to be used if there are two of them , is it have something to do with any factors regulate by cell environment?
There are many RNA binding protein who does this alternative polyadenylation job. Check out this article for a reference
www.frontiersin.org/articles/10.3389/fncel.2018.00518/full
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Aapka topic me material selection bhut Accha h😊
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Very Good Content
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Very nice video
great man! keep up!
But what happens to the mRNA that is still attached to the RNA Polymerase at 3:02?
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@@animatedbiologywitharpan
sure thing! but do you know the answer to my question?
I could not get your question! Could you please rephrase
@@animatedbiologywitharpan When the mRNA is cut to add the Poly A tail, there is a short mRNA strand that is still attached to the DNA-Polymerase complex. Look at 3:02
@@eminemlandsteiner168 I believe that all following mRNA on from the RNA polymerase will be degraded because there will be no more 5' capping of this RNA. The RNA polymerase will understand not to continue transcription partially due to this and also due to the fact that there will now be more phosphorylation on the serine2 than the serine5 on the CTD :)
again for poly A tail, thank you very much love love
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nice but further improvements required plz add more material with animation/diagram.
Why there is red part after 4 gene in brain cell dna isn't it wrong
Please can you type what CstF stands for? I didn't catch it
Cleavage stimulatory factor ..
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Nice explanation
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thank you for your really useful video
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thanks bro!! super helpful video
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Nice explanation 👍🏻
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Thank u... Helpful video
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Sir Kon si books se pdhate ho aap...?
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@@animatedbiologywitharpan txx uhh sir ..Allah apko khus rakhe ..🙏
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Thanku
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