Cephalosporin Pharmacology

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  • เผยแพร่เมื่อ 5 ต.ค. 2024

ความคิดเห็น • 109

  • @PS-pr5py
    @PS-pr5py 4 ปีที่แล้ว +101

    "The second generation is just a cluster-f*ck of different cephalosporins." THIS SHOULD BE IN EVERY MEDICAL TEXT!

  • @ans6441
    @ans6441 5 ปีที่แล้ว +175

    hi just a suggestion , for the fifth generation instead of learning all the foot symbols and universities , just say CefSTARoline , star has 5 sides ( the usual ones :) )

    • @DirtyMedicine
      @DirtyMedicine  5 ปีที่แล้ว +36

      this works too, I guess. I'm just a huge sports fan and it's easier for me to remember the Tarheel logo :)

    • @Sammy.a1287
      @Sammy.a1287 3 ปีที่แล้ว +7

      stars have 5 vertices, not sides

    • @dawaashukri6104
      @dawaashukri6104 2 ปีที่แล้ว +40

      @@Sammy.a1287 you only need to get the point.

    • @Supernova-217
      @Supernova-217 ปีที่แล้ว +1

      ​@@Sammy.a12875 pointed star, thats what they mean

  • @arturmukhamed-aliev9141
    @arturmukhamed-aliev9141 5 ปีที่แล้ว +39

    Also, you can memorize 5 gen as ⭐️ sTar - 5 pointed sTar.

  • @J1Sulliv
    @J1Sulliv 4 ปีที่แล้ว +96

    For the 2nd Gen Cephs, I've personally found the process of elimination method to be inadequate. "Fox Fur For Pro Tan-ning" is a good mnemonic to remember the big five: ceFOXitin, ceFURoxime, ceFaclOR, cefPROzil, cefoteTAN. Kinda dumb but it's proven reliable.

    • @drdhirajrajregmi
      @drdhirajrajregmi 2 ปีที่แล้ว

      Pros Wear Fake Fox Fur for Tea party
      cefPROzil CeFAClor CeFOXitin CeFURoxime CefoTEAtan

  • @rebeccaluoh7012
    @rebeccaluoh7012 ปีที่แล้ว +20

    Would love to see a general video on antibiotics and their mechanisms of action! Like mnemonic to help remember macrolides bind 50S, aminoglycosides bind 30S, fluoroquinolones bind DNA gyrase, etc. Can't remember them for the life of me. LOVING these pharm videos!!

    • @Supernova-217
      @Supernova-217 ปีที่แล้ว +12

      Macro means big, and 50S is bigger than 30S. Amino-glyco-side has 3 parts so 3 >>> 30S, abcdefg --> DFG --> DNA ,Flouroquinolone, Gyrase

    • @AliDarawshe
      @AliDarawshe ปีที่แล้ว +1

      @@Supernova-217thanks for this!

  • @hannahwading_room
    @hannahwading_room 3 ปีที่แล้ว +43

    dirty medicine: "alright gonna show you my super cool mnemonic for cephalosporin generation sorting"
    me, on my 22nd hour awake: "okay baby, show me your mnemonic"

  • @katelynhartupeemalett7124
    @katelynhartupeemalett7124 2 ปีที่แล้ว +8

    One comment - ceftazidime also has pseudomonas coverage! I remember it by cefTAZ for pseudomoNAZ

  • @atlboy2002
    @atlboy2002 4 ปีที่แล้ว +4

    BEST Cephalosporin video EVER. You saved me hours of headache, thanks man!!

  • @tzufanweng8810
    @tzufanweng8810 5 ปีที่แล้ว +10

    You are a LEGEND, dirty! Really appreciate for all these great videos. Just one request, is it possible to make one video about Mechanism & Classification of Antibiotic? Thank you, thank you, THANK YOU!!

  • @sann2952
    @sann2952 4 ปีที่แล้ว +3

    Omg love you!! You are GOD!! Classification of cephalosporin is crazy!! you've made it damn easy

  • @kamyathakkar1287
    @kamyathakkar1287 4 ปีที่แล้ว +7

    3rd generation - tri-POD includes cefPODoxime as well! :)

  • @chryslerfordgm
    @chryslerfordgm 5 ปีที่แล้ว +6

    Ceftazidime also covers pseudomonas

  • @Eternalfhilosophy
    @Eternalfhilosophy 17 วันที่ผ่านมา

    Hats off for your efforts, love you man

  • @connerlivingston947
    @connerlivingston947 3 ปีที่แล้ว +6

    For "cefdinir" I think of: dinner is the 3rd meal of the day. Also could relate to "diner" I suppose lol

  • @bookbites101quotes
    @bookbites101quotes 5 ปีที่แล้ว +12

    Cef-ixime , one of the most commonly used oral cephalosporin 🌝

  • @madhavsingla7903
    @madhavsingla7903 5 ปีที่แล้ว +6

    Hey all your efforts are highly appreciated
    I’m really thankful for all your videos...really great work!!
    Just one request
    Can you please upload your ethics video the one that was removed ??
    Exam in 10 days, I really need it!

  • @SuperKenshen
    @SuperKenshen 4 ปีที่แล้ว +1

    Pure genius, thank you.

  • @drswetaruparel
    @drswetaruparel 4 ปีที่แล้ว +1

    You are god sent !!! 👍😊🙏

  • @julieszczepanik4625
    @julieszczepanik4625 3 ปีที่แล้ว +2

    Love it!! Especially "a cluster f!@# of different cephalosporins"...thank you :)

  • @PowderChaser
    @PowderChaser 3 ปีที่แล้ว +7

    Thanks for another great video! I think it's absolutely ridiculous that we have to memorize pharm in the age of instant access to info.

  • @hannachoi9563
    @hannachoi9563 2 ปีที่แล้ว +2

    Thank you very much. Your videos really help. 👍

  • @medsplained4227
    @medsplained4227 4 ปีที่แล้ว +5

    For 2nd gen, if you want a pneumonic :) :
    I remember Cefuroxime by replacing "uro" with "duo" ("cefDUOxime"). Duo means two.
    I remember Cefoxitin by remembering that an OX has TWO horns.
    Love your videos btw!

  • @jax40001
    @jax40001 2 ปีที่แล้ว +1

    Gen 1: ALEX the First chicken wears a FEZ and PEcKS - cephALEXin - ceFEZazolin - Proteus, E.Coli, Klebsiella, Staph aureus (pre-surgical)

  • @krystenme6841
    @krystenme6841 2 ปีที่แล้ว +1

    Cool trick for 1st Generation is that all Cephalosporins starting with CefA belong to 1st like the 1st letter of the Alphabet, only exception is Cefaclor that is 2nd Gen.

  • @danielapinzon2921
    @danielapinzon2921 3 ปีที่แล้ว +3

    I literally giggle thanks for your vid

  • @medicaldispensary7660
    @medicaldispensary7660 3 ปีที่แล้ว

    ONE OF THE BEST EXPLANATIONS EVER ***

  • @joshuakatta7094
    @joshuakatta7094 2 ปีที่แล้ว +1

    jan : its not just a pattern of disrespect, its also inappropriate behaviour
    michael : DISSREE - my friend DISSRE got new SPECS - DISRESPECT , my friend INAPPRO drives a PRIUS
    jan: does that work for you?
    michael : yes.

  • @krupanidhi912
    @krupanidhi912 10 หลายเดือนก่อน

    Nice explanation on cephalosporins. Thanks

  • @sarah8844
    @sarah8844 ปีที่แล้ว

    oh my god you made cephs so much easy

  • @twinklelight1362
    @twinklelight1362 ปีที่แล้ว

    Your are a superman, thanks for this!!!

  • @oxell4925
    @oxell4925 ปีที่แล้ว

    Another great video, thank you!!!

  • @bobbiewa8876
    @bobbiewa8876 4 ปีที่แล้ว

    For hardstyle fans:
    Cef-Triax-ime & Cefix (Sephyx)-ime are 3rd generation cephalosporins

  • @susannivia.x2944
    @susannivia.x2944 3 ปีที่แล้ว +1

    Amazing explanation and mnemonic...

  • @khadijamohib5627
    @khadijamohib5627 2 ปีที่แล้ว +2

    For second gen
    This is kinda inapproritate
    FAC him in FOX FUR for FORTE 2 bucks
    So cefaclor cefoxitin cefuroxitime cofotetan and 2 means 2nd lol

  • @yairdonin
    @yairdonin 5 ปีที่แล้ว +2

    But Ceftazidime does work against Pseudomonas? Great video

  • @MedicalBlackBook
    @MedicalBlackBook 4 ปีที่แล้ว

    Your so adorable like seriously with all the pnemonics ... crushing it 👍🏻

    • @MedicalBlackBook
      @MedicalBlackBook 4 ปีที่แล้ว

      Pseu-do-mo-nas hahahaha so adourable

  • @juliusl5211
    @juliusl5211 3 ปีที่แล้ว +1

    Amazing work as always!

  • @alanwaterman1328
    @alanwaterman1328 ปีที่แล้ว

    In Tazmania they play 3 day cricket matches!

  • @shelchicago8997
    @shelchicago8997 3 ปีที่แล้ว

    Ingenious!

  • @cailinoconnell6981
    @cailinoconnell6981 2 ปีที่แล้ว

    The first one is really fun to ask in a British accent

  • @cometaire1
    @cometaire1 4 ปีที่แล้ว +3

    The more i watch dirty's video, the more i learn about America lol

  • @Rayodon
    @Rayodon 5 ปีที่แล้ว +5

    Just asking, does ceftazidime not provide pseudomonas coverage too?

  • @typhainesharon7383
    @typhainesharon7383 3 ปีที่แล้ว

    Really cool video clear and straightforward, but I recall that the first generation has more than 2 drugs, but at least now I know those 2 drugs

  • @donaldsheno7915
    @donaldsheno7915 2 ปีที่แล้ว

    Great video

  • @Avoug
    @Avoug ปีที่แล้ว

    The way I've memorized Cefepime:
    Pime is like Prime > 4 day shipping with prime.

  • @aliiraq9655
    @aliiraq9655 3 ปีที่แล้ว

    Cool .. thanks ..

  • @pouvoirdelamour8052
    @pouvoirdelamour8052 2 ปีที่แล้ว +2

    Please dirty could you also make videos of other antibiotics like aminoglycosides, penicillins and the likes

  • @alanwaterman1328
    @alanwaterman1328 ปีที่แล้ว

    For 5th generation we can think tar on your feet from the beach still using the five toes. There are good images for this to show toes foot and tar.

  • @danigarano3811
    @danigarano3811 2 ปีที่แล้ว

    super explanation, very helpful

  • @suomynonaanonymous
    @suomynonaanonymous 5 ปีที่แล้ว

    Tyty I have had sooooooo much trouble with this!

  • @abhaychaniyara6003
    @abhaychaniyara6003 3 ปีที่แล้ว

    awesome bro .....

  • @rangsilandrew3542
    @rangsilandrew3542 5 ปีที่แล้ว

    drugs that have cef- prefix and 't' in them are 3rd gens cephalosporin drugs like cef-t-azidime, cef-t-riaxone, cefo-t-axime

  • @KP-jp8bp
    @KP-jp8bp 5 ปีที่แล้ว

    Thank you so much!!!!
    Please do a video on Hep B serologic markers and also Bacterial and Viral genetics if it’s high in demand 🙏🏻😊
    Appreciate all your help.

  • @kleopatrarn135
    @kleopatrarn135 5 ปีที่แล้ว

    You are amazingly awesome 👏🏼💜

  • @chelsycalhoun4422
    @chelsycalhoun4422 5 ปีที่แล้ว

    Great video!

  • @sabrinan400
    @sabrinan400 3 ปีที่แล้ว +1

    you could also say "TAR-sals" and you have 5 toes..

  • @mdsohail6921
    @mdsohail6921 5 ปีที่แล้ว

    No words just thankyouuu😊

  • @wernernalule1783
    @wernernalule1783 4 ปีที่แล้ว

    Ceftriaxone covers pseudomonas as well

    • @cometaire1
      @cometaire1 4 ปีที่แล้ว

      Textbook says ceftriaxone doesnt cover pseudomonas

    • @wernernalule1783
      @wernernalule1783 4 ปีที่แล้ว

      Check it out on medscape and Clinical pharmacology 5th edition by James Butler

    • @richardelias4788
      @richardelias4788 4 ปีที่แล้ว

      @@wernernalule1783 yeah, lippincott suggests like wise too.

  • @Starlightserenity
    @Starlightserenity 4 ปีที่แล้ว +3

    Love the mnemonics but I think you should at least list the second generations since it’s actually not accurate to say that all cephs not mentioned here fall under 2nd gen. What about cefpodoxime? Oral third gen that’s not uncommon. A disclaimer that acknowledges this is not an all-inclusive list would be helpful.
    Also, cefepime is not the only cephalosporin with pseudomonas coverage. Ceftaz too.

  • @hannachoi9563
    @hannachoi9563 2 ปีที่แล้ว

    For Third generation, cefdinir: I remembered it as “dinner is the third meal.”

  • @awesomooo6372
    @awesomooo6372 ปีที่แล้ว

    ❤ wow

  • @TheGardenDoc
    @TheGardenDoc 2 ปีที่แล้ว

    "It's a small rodent thing found in Australia" HAHA

  • @DocLiabrary2k17
    @DocLiabrary2k17 8 หลายเดือนก่อน

    🎉

  • @junaidmushtaq9421
    @junaidmushtaq9421 5 ปีที่แล้ว

    sir plz make a video on Antidepressants plz ,

  • @felipepubillones2768
    @felipepubillones2768 3 ปีที่แล้ว

    Taz does triple taxes
    But better mnemonic i feel

  • @kaynoow95
    @kaynoow95 3 ปีที่แล้ว +1

    LET’S GO HEELS!!!

  • @AYoungDoctorsJourney
    @AYoungDoctorsJourney 3 ปีที่แล้ว

    It causes vitamin k deficiency?! 😭 never knew this (and so much more)

  • @markpentland7780
    @markpentland7780 5 หลายเดือนก่อน

    cluster fuck was personal lmao

  • @profssrfunk
    @profssrfunk 5 ปีที่แล้ว

    Any chance we will get an HIV tx video?

  • @jaynapatel7376
    @jaynapatel7376 5 ปีที่แล้ว +1

    i tried to tweet you, but it says the acct no longer exists? ive also emailed you haha!

    • @DirtyMedicine
      @DirtyMedicine  5 ปีที่แล้ว +5

      hey jayna. I'm not on Twitter any more.. it felt pretty useless to me. I read every email I get, so if you emailed me I definitely already read it

  • @ccblan2
    @ccblan2 3 ปีที่แล้ว

    Obviously outdated at the time I'm writing this due to new drugs on the market but even when published you left out several drugs. You say to assign anything not mentioned to the 2nd generation but what about cefdinir, cefditoren, cefixime, cefpodoxime, and ceftibuten which are 3rd generation. I would hate for students to confuse this as a complete list.

    • @DirtyMedicine
      @DirtyMedicine  3 ปีที่แล้ว +1

      This is strictly for USMLE/COMLEX

  • @yourremarkablyaveragepal781
    @yourremarkablyaveragepal781 5 ปีที่แล้ว +2

    Face reveal! hahah. Thank you as always.

  • @SaiRam-nz9sy
    @SaiRam-nz9sy 3 ปีที่แล้ว +1

    Imma make sure my man dirty here gets a fat cut from my first stipend

  • @aminakhan8533
    @aminakhan8533 ปีที่แล้ว

    I came up with my own stupid dirty mnemonic for the second gen drugs “I FOT FOX, FAM said FAC(fu*k) FUR”

  • @2468ayesha2468
    @2468ayesha2468 5 ปีที่แล้ว +1

    MORE MORE MOOOREE🤪🤓

  • @drobyd
    @drobyd 5 ปีที่แล้ว +1

    U g0t the first like fr0m me 😁😁

  • @kiousagi
    @kiousagi 5 หลายเดือนก่อน

    CephALEXin... Alex came in first. CeftAROLINE...Caroline came in last (fifth).

  • @mayurkhan9654
    @mayurkhan9654 3 ปีที่แล้ว

    Need parasitology pharm please.

  • @tabithalewis5942
    @tabithalewis5942 ปีที่แล้ว

  • @ShibekeDerick-cl5oc
    @ShibekeDerick-cl5oc 7 หลายเดือนก่อน

    I just found out that there's is a 6th generation guys

  • @victormanuel1977
    @victormanuel1977 5 ปีที่แล้ว +1

    klk hi

  • @Li-yn5rz
    @Li-yn5rz 4 ปีที่แล้ว +1

    I love you but you repeat yourself so much that you make the video 5x than it has to be...

    • @rosstaylor7743
      @rosstaylor7743 2 ปีที่แล้ว +1

      this repetition is the thing that helps us with memorization