Antiviral Pharmacology

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  • เผยแพร่เมื่อ 4 มิ.ย. 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

ความคิดเห็น • 99

  • @Lucky-ff9pd
    @Lucky-ff9pd 4 ปีที่แล้ว +239

    The voices of med school I've become very attached to: Dr. Sattar, Dr. Ryan, Sketchy Micro guy, and Dirty USMLE

    • @fereshtahkhoshbakht1999
      @fereshtahkhoshbakht1999 4 ปีที่แล้ว

      Me too

    • @dailyusmle8710
      @dailyusmle8710 4 ปีที่แล้ว

      @@fereshtahkhoshbakht1999 Whos Dr. Ryan?

    • @janicedsouza3087
      @janicedsouza3087 4 ปีที่แล้ว +6

      @@dailyusmle8710 He's the one who makes "Boards and beyond" videos

    • @duhaarafique1271
      @duhaarafique1271 3 ปีที่แล้ว

      Same!

    • @gloriac9994
      @gloriac9994 2 ปีที่แล้ว +20

      Dude same lol. I get so much comfort when I hear dirty talking, like its all gonna be okay

  • @alitantawy2222
    @alitantawy2222 ปีที่แล้ว +11

    one way to remember the hep c drugs :
    -If it ends with "previr" like "previous" so think NS3/4A , also starts with p as in protease .
    -" ASVIR " like after and starts with an A so think "NS5A"
    -"BUVIR" starts with b so think "NS5B"

  • @obadadaher4851
    @obadadaher4851 2 ปีที่แล้ว +14

    give CIDofovir with probeneCID

  • @professorkhan5315
    @professorkhan5315 4 ปีที่แล้ว +46

    Really great video!! I wanna add that a major differentiating factor between Foscarnet and Cidofovir is that Foscarnet has a seizure risk (I just think of S for seizure)

  • @redache467
    @redache467 4 ปีที่แล้ว +45

    -previr = protease
    -buvir = 5B RNA bolymerase
    -asvir = 5A

  • @user-ul2sd8yc3g
    @user-ul2sd8yc3g 3 ปีที่แล้ว +34

    As usual, Great video
    One note , i think that viral thymidine kinase adds only one phosphate to some of the anti-herpetic drugs ( acyclovir , valacyclovir and famciclovir as I remember) and the other 2 phosphate groups are added by cellular kinases, not the viral one

  • @Umir445566
    @Umir445566 4 ปีที่แล้ว +31

    Thank you so much dude You are a legend. Any chance we can get a signaling mechanisms videos for hormones?

  • @akinolarukayat6475
    @akinolarukayat6475 2 ปีที่แล้ว +1

    Have had trouble remembering and understanding these drugs. You made it easier to assimilate. Thank you

  • @brookeanderson2631
    @brookeanderson2631 11 หลายเดือนก่อน

    Love the way you come up with tips and tricks to remember names and mechanism of action. Thanks!

  • @latifullah8574
    @latifullah8574 3 ปีที่แล้ว +5

    You made it so easy and I am waiting eagerly for HIV anti vitals. Thanks for helping us

  • @IG-qv6sh
    @IG-qv6sh 3 ปีที่แล้ว +6

    I'm waiting for part 2 of it. This was the most helpful thing in my learning antivirals

  • @SG-gw5xo
    @SG-gw5xo 2 ปีที่แล้ว

    Thank you so much for the video, you deserve 1 million subscribers!!!

  • @wacomundo9599
    @wacomundo9599 11 หลายเดือนก่อน

    Dude, thanks so much! I’ve had to give avyclovir a handful of times in the ED and i never new the actual mechanism behind it.

  • @pallavighatnekar1653
    @pallavighatnekar1653 2 ปีที่แล้ว +2

    For cidofavir you can remember given IV saline as I V is in the name cidofa VI r. Thanks so much for your information Dirty Medicine.

  • @serellamadole
    @serellamadole 2 ปีที่แล้ว

    Great video! You made the material so easy to digest.

  • @luckymaisha
    @luckymaisha 4 ปีที่แล้ว +26

    Can you possibly do one on antibiotics/microbials? Love your videos by the way!!! Thanks so much for making them

    • @abiraafzal7171
      @abiraafzal7171 3 ปีที่แล้ว +1

      Please do a video on antibiotics!!

  • @saintsam7397
    @saintsam7397 2 ปีที่แล้ว +1

    THANKYOU FOR NEVER ADDING MUSIC TO YOUR GOLDEN VIDEOS.

  • @stephenharris-dr
    @stephenharris-dr 7 หลายเดือนก่อน

    8:23 - I think it is because of the purine ring structures in the drugs (Acyclovir, Valcyclovir and Famcyclovir). Anyway, your channel help me a lot during my preparation for MRCP part 1 and part 2 written exams. I really appreciate it. Thank you.

  • @xaaboopinkly
    @xaaboopinkly 4 ปีที่แล้ว +3

    I really don’t know how to thank you!!!!!!

  • @AnilKumar-lo5rn
    @AnilKumar-lo5rn 3 ปีที่แล้ว

    i watchd ur videos ovarion tumours very excellent sir....nice pneumonice.....its very help a lot for me

  • @junaidmushtaq9421
    @junaidmushtaq9421 3 ปีที่แล้ว

    Thank you so much.. This is high yield for board examinations and u made is easy for us.😍

  • @xxamulyaxx
    @xxamulyaxx 4 ปีที่แล้ว +1

    thanks mate...
    simple slides...
    love from INDIA.

  • @ddfelder2
    @ddfelder2 4 ปีที่แล้ว

    Thank you!

  • @4agus
    @4agus ปีที่แล้ว

    Great video, so useful! you made it really easy. Thanks Dirty

  • @Muuip
    @Muuip 4 ปีที่แล้ว

    Great summary!
    Very helpful! 👍

  • @tijinmathew6478
    @tijinmathew6478 3 ปีที่แล้ว

    In hepatis C NS5B inhibitor which is a RNA -DEPENDENT RNA polymerase is supposed to block step n0 .3 right?

  • @ambersani6889
    @ambersani6889 3 ปีที่แล้ว

    Thank you, Sir... plz upload part 2 as well

  • @drhoneybee973
    @drhoneybee973 2 ปีที่แล้ว

    Dirty med you are great👍👍..thank you for making things easy-peesy..by any chance we could get a vid on anti-microbials!!!

  • @raulblancoazcuy8308
    @raulblancoazcuy8308 3 ปีที่แล้ว

    I loved your video. Thanks

  • @marine3144
    @marine3144 4 ปีที่แล้ว +2

    You just taught me better than my prof

  • @raghadraghad7976
    @raghadraghad7976 2 ปีที่แล้ว

    so helpful ! thanks a lot

  • @drswetaruparel
    @drswetaruparel 4 ปีที่แล้ว

    Very helpful !!! Thanks 👍

  • @Lucky-ff9pd
    @Lucky-ff9pd 4 ปีที่แล้ว +1

    Cellular enzymes add the 2nd and 3rd phosphate

  • @abdulmohsenalmutairi7102
    @abdulmohsenalmutairi7102 2 ปีที่แล้ว

    Thx 🙏

  • @awesomepabla7061
    @awesomepabla7061 3 ปีที่แล้ว

    God bless you

  • @PowderChaser
    @PowderChaser 3 ปีที่แล้ว

    Another beautiful video!

  • @mahnoor7726
    @mahnoor7726 ปีที่แล้ว

    Love all of your videos 👌👌👌👌

  • @vinodalbuquerque2488
    @vinodalbuquerque2488 2 ปีที่แล้ว

    Sir plz explain on Lamuvidine HBV antivirals inhibitors.

  • @marianacostaR
    @marianacostaR 3 ปีที่แล้ว

    Very good!! As usual

  • @Lopakaracing
    @Lopakaracing ปีที่แล้ว

    I can't find the JOIN button anywhere.

  • @yashpawate1306
    @yashpawate1306 4 ปีที่แล้ว +3

    This is just in time for my Microbiology shelf exam. Thank you so much! Please upload the HIV drugs too before saturday!

  • @emrecan-qy6uq
    @emrecan-qy6uq 9 หลายเดือนก่อน

    Can you do one about NSAIIs and Antibiotics? And I wonder why you didn't mention other Hepatitis types?

  • @bhatwasim2831
    @bhatwasim2831 3 ปีที่แล้ว +1

    Love from Kashmir

  • @christopherpatrick6949
    @christopherpatrick6949 4 ปีที่แล้ว +9

    Dirty, the absolute worst topic to learn is pediatric developmental milestones. If you could make a video for that I would be eternally grateful.

    • @sayedaali6730
      @sayedaali6730 4 ปีที่แล้ว

      Christopher Patrick he already did

    • @christopherpatrick6949
      @christopherpatrick6949 4 ปีที่แล้ว +1

      @@sayedaali6730 Are you sure? Do you have a link to the video?

  • @tinashealthbeautyworld8396
    @tinashealthbeautyworld8396 4 ปีที่แล้ว +4

    Can you also please do Molecular cell videos too? Thank you 🙏 so much in advance

  • @cayladoo_1
    @cayladoo_1 ปีที่แล้ว

    u r amazing

  • @ramzarukia120
    @ramzarukia120 4 ปีที่แล้ว

    love it

  • @elsatkkful
    @elsatkkful 4 ปีที่แล้ว +7

    Hey Dirty! Thank you for your videos, I know you're working hard to bring us these videos. Could you please make a video on the high yield microbiology. Thank you

    • @DirtyMedicine
      @DirtyMedicine  4 ปีที่แล้ว +11

      It’s a huge topic of that I would need to break into several smaller videos

    • @aj7147
      @aj7147 4 ปีที่แล้ว +1

      @@DirtyMedicine pls make more and more pharma and immuno videos pleaseeee !you the besttt....pls open a blog too like medicoawesome

    • @christopherpatrick6949
      @christopherpatrick6949 4 ปีที่แล้ว +2

      This is what sketchy is for

  • @pramodthapa2517
    @pramodthapa2517 4 ปีที่แล้ว +1

    desperately waiting Viral Hepatitis doc

  • @enginoengin1174
    @enginoengin1174 4 ปีที่แล้ว +3

    Part 2 pretty please 🤓🤓

  • @MedManiac1
    @MedManiac1 3 ปีที่แล้ว

    legend!🔥🔥

  • @nurulaliahrizal
    @nurulaliahrizal 4 ปีที่แล้ว +1

    You're an incredible teacher! Btw please do anti-HIV video.

  • @mohamedmetwalli3064
    @mohamedmetwalli3064 2 ปีที่แล้ว

    awesome

  • @Greanestbean
    @Greanestbean 5 หลายเดือนก่อน

    Awesome

  • @kenmiguel2986
    @kenmiguel2986 3 ปีที่แล้ว

    Please do an HiV antiviral video

  • @crimzonart1269
    @crimzonart1269 3 ปีที่แล้ว +1

    Please upload video on floppy infant
    Regards
    Dr. Gawher

  • @alih6953
    @alih6953 3 ปีที่แล้ว +1

    Great video mate amazing job! I think there is mis-spelling. It is Simeprevir

  • @monirafarah4391
    @monirafarah4391 2 หลายเดือนก่อน

    Is this for step 2 only? I heard him say step 2 and I’m studying for step 1?

    • @kenibe3507
      @kenibe3507 หลายเดือนก่อน

      You need to know this for step 1.

  • @usmleislife3396
    @usmleislife3396 4 ปีที่แล้ว +2

    Hey can u make video on biostat hypothesis alpha and beta errors confidence interval... it will be very helpful

    • @otto9875
      @otto9875 4 ปีที่แล้ว

      Search on here USMLE biostatistics. There’s a guy i think his names Dr. randy something who Dirty endorsed for his bio stats review. It’s good

  • @PtolemyXVII
    @PtolemyXVII 4 ปีที่แล้ว

    Very interesting! However 1) the antivirals in the AMI group would also block exosomes- due to exosomes uptake of sialic acid, and therefore also affect exosomes' action on T-cells by inhibiting them. Wouldn't this be hugely problematic and compromise the immune system? 2) the antivirals in the cyclone group, wouldn't it also inhibit RNA polymerase in cardiac cells as well as other normal cells due to its inhibition of thyamine kinase? This would mean that normal cells wouldn't be able to replicate. Thoughts?

    • @Ifeany1
      @Ifeany1 3 ปีที่แล้ว

      the drugs are activate by the virus....the first phosphylation step, making it more specific to cells infected by the virus.

  • @mohammadadnan6374
    @mohammadadnan6374 3 ปีที่แล้ว

    U need to make your own course like pathoma or b@b

  • @lichh64
    @lichh64 2 หลายเดือนก่อน

    I love u.

  • @yasinozkul6590
    @yasinozkul6590 3 ปีที่แล้ว +1

    l-e-d-i-p-A-svir (5A)
    s-o-f-o-s-B-uvir (5B)

  • @missionvision99
    @missionvision99 7 หลายเดือนก่อน

    3:39 6:14 8:11 10:15 11:12 12:29 17:27 18:40 fo SSS carnet

  • @Ruqaya_pearl
    @Ruqaya_pearl 4 ปีที่แล้ว +4

    I dont know why im here, i have a surgery exam!

  • @majidbashir7102
    @majidbashir7102 3 ปีที่แล้ว +1

    Hi sir.
    Isn't part 2 yet available,???
    Part 2 of this video Non HIV drugs ??

  • @alhasanmd7305
    @alhasanmd7305 3 ปีที่แล้ว

    Pharmacology profs disliked this video

  • @lgchinadragon
    @lgchinadragon 2 หลายเดือนก่อน

    thymidine kinase, not thymididine kinase, which you keep on saying. I get this too with phenylalanine lol

  • @maryalex9316
    @maryalex9316 2 ปีที่แล้ว

    I just wanna express my gratitude to Dr.Ono on TH-cam for curing my HSV 1&2. God will bless you Dr Ono

  • @coverton
    @coverton ปีที่แล้ว

    Sofo5Buvir

  • @bobbyboygaming2157
    @bobbyboygaming2157 3 ปีที่แล้ว

    your video would be half as long and easier to watch if you didnt wast so much time saying "this is like so high yield" like every 5 seconds

  • @younaskhan7343
    @younaskhan7343 ปีที่แล้ว

    For best pharmacology classes follow Dr Malik Nouman official