In addition to therapy with medication, it is a good idea to support the therapy with losing body fat (it produces estrogen) and pay attention to liver health (it also metabolizes estrogen and it can't do it properly if it's fatty, enlarged or has other issues). The therapy will be over in an X number of years, but we don't want to fall into the same trap and have cancer recurrence due to continuing estrogen surplus in the body.
For people who can lose weight, there are many benefits. Other people find that losing fat is not possible and that they actually gain back the weight and fat and end up weighing even more.
Reading everyone's comments just reinforces the idea of how unique our cases are. Even within the HR+ HER2- group, so many differences between our cases and treatments have to be tailored. What a long road.....hopefully.
It's truly eye-opening to see the variety in everyone's stories, isn't it? It just goes to show how personalized each individual's journey is. Thank you for watching!
You're doing a wonderful thing by gathering information to support your mom. If you have any more questions or need further guidance, we're here to help. Wishing you and your mom strength and resilience on this journey.
Thank you so much for explaining this so well. I have learned so much from your videos. I am five years post HER2+ diagnosis and doing well so far, but I have just now begun to learn and study what exactly is my particular BC and how it occurred. I don’t know if it is a coincidence that I got my BC after a year on bio identical hormone therapy. I thought I was protecting myself against heart attacks, ironically BC, and Alzheimer’s. And then I ended up with this BC. If you can do a video explaining or educating us on The relationship between bio identical hormone therapy and protection against BC, that would be appreciated. Focus at the moment is doing my best to prevent its recurrence, which I wished my doctors would’ve explained to do this initially. I learned later that there’s more to it than just finishing up with chemo and radiation, and basically my doctors wiped their hands and said I was done. But you’re never done because if you continue to do what you’ve always done, and don’t do anything different, it may recur. 😳
Yes, the doctors are mainly concerned about medical treatment and don't say much about prevention. It's like on one hand they want you to get healthy and on the other to come back with the same issue in a while😢
There is a lack of large, long-term studies evaluating the risks and side effects of compounded bioidentical hormones. It is extremely unlikely, however, that one year of use contributed to your breast cancer in any way. The increase in the risk of breast cancer with prescribed hormone replacement therapy is in people with many years of use. We're so happy you find the videos helpful.
@@yerbba thank you so much for your response. It makes me feel better actually that I didn’t contribute to my own diagnosis by taking bio identical hormones. I want to believe that it did not cause my BC. Other thoughts I had is that it fed The tumor kind of like putting fertilizer on a plant. anyway, I guess I was just at the right age (62) to have BC. five years into it however I’m doing pretty well but I have learned while attending an excellent summit on breast cancer put out by Dr. Jen Simmons and Dr. Veronique DeSaulnier (sp ?) that there was a lot I could’ve done to prevent its reoccurrence all this time. So now I am rushing to get caught up on health practices I wish I would’ve known right after chemo and radiation. It’s never too late to start, I am on that journey now. Thank you again for your great videos that I never miss.
Good morning Dr., Understanding what was frequently thought and sounds counterproductive, wondering whether you've looked at the latest positive research on HRT for side effects of the anti estrogen therapy. Especially for post menolausal women. Thank you.
Hormone replacement therapy is extremely effective at relieving symptoms. In people with a history of breast cancer, however, such therapy may increase the risk of recurrence and is therefore advised against.
Hi, i had her2 positive breast cancer ,caught early thank god ,grade 2 and had not spread, i have had a mastectomy but was told i did not need Radiotherapy is this usual ?was expecting Radiotherapy, im now on kadcyla infusions and taking Exemestane but im suffering real bad bone pain ,arthritis in my fingers to i find it hard to sleep, i no alot of women have suffered the same ,sovhas come of these ,but im frightened that if i stop then i will have a recurrence, notcsurecwhat to do ,cant carry on long term with this pain ,has anyone gotcany Advice?thank you
Thanks for sharing your experience. Radiation therapy after mastectomy is part of treatment plans in people with more than 3 positive lymph nodes or if the cancer is greater than 5 cm. In people who are very young, radiation therapy may be offered with smaller tumors or 1 - 3 positive lymph nodes. It sounds as if your cancer was smaller and your lymph nodes were negative. In terms of the symptoms from exemestane, it is the case that many people feel better on a different aromatase inhibitor. Talking with your medical team would be a good first step.
Thanks for educating me in a more clear way. This past June had a Masectomy for HR+ PR+ HER2-, 2.4cm tumor removed in right breast. Nodules are clear and thankfully no need for radiation or chemo because oncotype was -1%. The plan of action now is to take Anastrozole 1mg in addition to Goserelin shot every 3 months. Any thoughts on this plan of action will be appreciated. I'm afraid of all the side effects of the pill plus a shot every 3 months...
Thank you for sharing your experience. It's great to hear that your surgery went well and that you don't need radiation or chemotherapy. Anastrozole and goserelin are standard treatments for HR+ PR+ breast cancer. While the potential side effects can be concerning, these medications can significantly reduce the risk of recurrence. Discussing your concerns with your oncologist can help you find ways to manage any side effects effectively. Your health and comfort are very important.
GREETINGS DOCTOR GRIGGS HAVE A QUESTION ? LETS SAY IF A PATIENT IS ON TAMOXIFEN , AND THAT PATIENT DONT HAVE ANY SIDE EFFECTS ,OR SHOWS ANYS SYMPTOMS SO DOES THAT MEANS THAT TAMOIFEN IS REALLY WORKING ON THAT PATIENT , THANKS 😊
This is a good question. Some people feel like their treatment is working better if they get side effects and some studies have shown that side effects may be associated with a good response. It is not clear that people without side effects will not benefit, however. Thank you for your question.
Doing well on Anastrazole (year 2). Question on how decision is made to take endocrine therapy for 5 years versus 10 years. Will it depend on the studies at the time you reach your 5 year mark, risk analysis of side effects to bones from dexa scan or is additional testing done on the tumor itself? Thanks for your video!
@user-xo8hq2go7g how has your body responded to anastrozole? I have yet to start, having been diagnosed with an early stage of cancer, but I'm curious to know how your bones and joints have been, and how you're feeling? There are so many who have horror stories, but I'm scared and wish to hear good things (if there are any). Please help with your response. Thank you.
I was apprehensive before starting anastrazole, but have found it to be nearly symptom free. Was 62 at diagnosis. Hit a deca scan and have slight osteopenia. Had achy joints at the 3-6 month mark, but then resolved. I’ve been an avid runner and gym enthusiast since college so that may be helping. Also, I didn’t really have menopause symptoms when went through it. I’ve been hopeful in taking anastrazole knowing it’s going to be a long treatment. When i take it I have it framed in my mind as being a little insurance policy against recurrrence. I’ll be thinking of you and wishing you a smooth adventure with it too! 😊
I read your story and was very surprise by similarity to mine.I have one question to you,are you receiving bisphosphonates.I was offered one with DEXA T minus 1.2.I refused to take this drug and I can't stop worry about progression to osteoporosis.
I’ve asked my oncologist about the need for bone strengthening medication - asking if it’s better to be proactive. Her view is I only slightly have osteopenia and we don’t know it will progress. I will have my next dexa scan in Dec and we’ll compare to the previous. I prefer regular exercise keeping my bones strong if that will work versus a medication that will also bring side effects. I’ve asked about Zometa and Prolia specifically.
Hi, thanks for your videos 🥺. My mom has T1N1M0 HR+HER2- breast cancer, I’m doing a lot of research to explain her all reports, she’s very worried about needing chemo, doctors said that It will be radiation only but it’s scary to not taking chemo with that positive lymph node 😔 unfortunately in my country is very hard to do genomic test like oncotype, what should we do?
Since genomic testing like Oncotype is hard to access in your country, it's important to rely on your medical team's expertise. They likely considered various factors, including your mom's overall health and specific cancer characteristics.
Hormonal therapy is designed to target remaining cancer cells that are hormone receptor-positive and can help prevent recurrence. It's an important part of treatment for many breast cancer survivors.
Hello Dear Dr. Griggs, My mother age is 65 years old Dcis: present Size of largest dcis foci: 2mm Type: micropapillary, cribriform, papillary, solid Nuclear grade: grade3, marked nuclear pleormorphism Impression: Invasive ductal carcinoma,NST,grade2 All 4 node nagative Margins: deep resection margin is 3 mm away from tumer. all other resected margins are free of tumer Pathological stage: pt2Nsn(0)mx Tumer size: 3.2×2.8×2 c.m Tumer focality: unifocal Histological grade: grade2,score7 Strongly er+ (100%), pr- (0), her2 +1(nagative) Canasst oncostem low risk score is 9.9 Dear Dr. Griggs Please tell me which type of bc is this? Reqiurement of chemo or not i am in confusing situation please help me😢
Thanks for writing. Your mother is fortunate to have you looking out for her. This cancer would be classified as a Stage II infiltrating ductal carcinoma with DCIS present in the tumor. For our other viewers, OncoStem is a genomic assay that analyzes biomarkers in the tumor tissue sample using its own algorithm to determine a risk score. This risk score predicts the likelihood of cancer recurring within 5 years post-surgery. Based on the risk score, patients are classified as "low-risk" or "high-risk" for recurrence. In general, regardless of the assay, people with tumors classified as low risk do not benefit from chemotherapy. Of course, each person's situation is unique, and her doctors and she should discuss the results and their recommendations. We hope this is helpful.
Yes, N1mi is considered early and refers to a minimal spread of cancer to lymph nodes, typically microscopic. It often indicates a relatively low level of lymph node involvement, but your doctor can give you a full picture based on your specific case.
So this is interesting…high estrogen levels in the body do not cause breast cancer. That is, drawing blood levels of estrogen would not identify people at higher risk. Once breast cancer has been established, however, blocking estrogen from getting to any breast cancer cells is an effective therapeutic strategy. One link between breast cancer and estrogen is that prolonging estrogen exposure (by taking estrogen replacement therapy for many years) can increase the risk of breast cancer somewhat.
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In addition to therapy with medication, it is a good idea to support the therapy with losing body fat (it produces estrogen) and pay attention to liver health (it also metabolizes estrogen and it can't do it properly if it's fatty, enlarged or has other issues). The therapy will be over in an X number of years, but we don't want to fall into the same trap and have cancer recurrence due to continuing estrogen surplus in the body.
For people who can lose weight, there are many benefits. Other people find that losing fat is not possible and that they actually gain back the weight and fat and end up weighing even more.
Reading everyone's comments just reinforces the idea of how unique our cases are. Even within the HR+ HER2- group, so many differences between our cases and treatments have to be tailored. What a long road.....hopefully.
It's truly eye-opening to see the variety in everyone's stories, isn't it? It just goes to show how personalized each individual's journey is. Thank you for watching!
thank you so much! my mom just got diagnosed with IDC HER-2 + so I am learning everything I can to help her in anyway I can
You're doing a wonderful thing by gathering information to support your mom. If you have any more questions or need further guidance, we're here to help. Wishing you and your mom strength and resilience on this journey.
Same how's she ?
Thank you so much for explaining this so well. I have learned so much from your videos. I am five years post HER2+ diagnosis and doing well so far, but I have just now begun to learn and study what exactly is my particular BC and how it occurred. I don’t know if it is a coincidence that I got my BC after a year on bio identical hormone therapy. I thought I was protecting myself against heart attacks, ironically BC, and Alzheimer’s. And then I ended up with this BC. If you can do a video explaining or educating us on The relationship between bio identical hormone therapy and protection against BC, that would be appreciated. Focus at the moment is doing my best to prevent its recurrence, which I wished my doctors would’ve explained to do this initially. I learned later that there’s more to it than just finishing up with chemo and radiation, and basically my doctors wiped their hands and said I was done. But you’re never done because if you continue to do what you’ve always done, and don’t do anything different, it may recur. 😳
Yes, the doctors are mainly concerned about medical treatment and don't say much about prevention. It's like on one hand they want you to get healthy and on the other to come back with the same issue in a while😢
There is a lack of large, long-term studies evaluating the risks and side effects of compounded bioidentical hormones. It is extremely unlikely, however, that one year of use contributed to your breast cancer in any way. The increase in the risk of breast cancer with prescribed hormone replacement therapy is in people with many years of use. We're so happy you find the videos helpful.
@@yerbba thank you so much for your response. It makes me feel better actually that I didn’t contribute to my own diagnosis by taking bio identical hormones. I want to believe that it did not cause my BC. Other thoughts I had is that it fed The tumor kind of like putting fertilizer on a plant. anyway, I guess I was just at the right age (62) to have BC. five years into it however I’m doing pretty well but I have learned while attending an excellent summit on breast cancer put out by Dr. Jen Simmons and Dr. Veronique DeSaulnier (sp ?) that there was a lot I could’ve done to prevent its reoccurrence all this time. So now I am rushing to get caught up on health practices I wish I would’ve known right after chemo and radiation. It’s never too late to start, I am on that journey now. Thank you again for your great videos that I never miss.
Thank you, Dr.Griggs, for your continuous support for breast cancer (health).
Thank you for your continuous support!
Good morning Dr., Understanding what was frequently thought and sounds counterproductive, wondering whether you've looked at the latest positive research on HRT for side effects of the anti estrogen therapy. Especially for post menolausal women. Thank you.
Hormone replacement therapy is extremely effective at relieving symptoms. In people with a history of breast cancer, however, such therapy may increase the risk of recurrence and is therefore advised against.
Ok, Thank you Dr. Grigg.
Another excellent info video. Four months after mastectomy. Soon to start AI, and CDK inhibitor
We're glad you found the video helpful! Thanks for sharing your experience, and we're hoping your feel okay on your medications.
Hi, i had her2 positive breast cancer ,caught early thank god ,grade 2 and had not spread, i have had a mastectomy but was told i did not need Radiotherapy is this usual ?was expecting Radiotherapy, im now on kadcyla infusions and taking Exemestane but im suffering real bad bone pain ,arthritis in my fingers to i find it hard to sleep, i no alot of women have suffered the same ,sovhas come of these ,but im frightened that if i stop then i will have a recurrence, notcsurecwhat to do ,cant carry on long term with this pain ,has anyone gotcany Advice?thank you
Anastrozole really messed me up
Thanks for sharing your experience. Radiation therapy after mastectomy is part of treatment plans in people with more than 3 positive lymph nodes or if the cancer is greater than 5 cm. In people who are very young, radiation therapy may be offered with smaller tumors or 1 - 3 positive lymph nodes. It sounds as if your cancer was smaller and your lymph nodes were negative.
In terms of the symptoms from exemestane, it is the case that many people feel better on a different aromatase inhibitor. Talking with your medical team would be a good first step.
Thanks for educating me in a more clear way. This past June had a Masectomy for HR+ PR+ HER2-, 2.4cm tumor removed in right breast. Nodules are clear and thankfully no need for radiation or chemo because oncotype was -1%. The plan of action now is to take Anastrozole 1mg in addition to Goserelin shot every 3 months. Any thoughts on this plan of action will be appreciated. I'm afraid of all the side effects of the pill plus a shot every 3 months...
Thank you for sharing your experience. It's great to hear that your surgery went well and that you don't need radiation or chemotherapy. Anastrozole and goserelin are standard treatments for HR+ PR+ breast cancer. While the potential side effects can be concerning, these medications can significantly reduce the risk of recurrence. Discussing your concerns with your oncologist can help you find ways to manage any side effects effectively. Your health and comfort are very important.
Does ketogenic diet helps aromatase inhibitors and Verzenio work better?
No, there is no proven benefit of a ketogenic diet.
GREETINGS DOCTOR GRIGGS
HAVE A QUESTION ? LETS SAY IF A PATIENT IS ON TAMOXIFEN , AND THAT PATIENT DONT HAVE ANY SIDE EFFECTS ,OR SHOWS ANYS SYMPTOMS SO DOES THAT MEANS THAT TAMOIFEN IS REALLY WORKING ON THAT PATIENT ,
THANKS 😊
This is a good question. Some people feel like their treatment is working better if they get side effects and some studies have shown that side effects may be associated with a good response. It is not clear that people without side effects will not benefit, however. Thank you for your question.
Doing well on Anastrazole (year 2). Question on how decision is made to take endocrine therapy for 5 years versus 10 years. Will it depend on the studies at the time you reach your 5 year mark, risk analysis of side effects to bones from dexa scan or is additional testing done on the tumor itself? Thanks for your video!
@user-xo8hq2go7g how has your body responded to anastrozole? I have yet to start, having been diagnosed with an early stage of cancer, but I'm curious to know how your bones and joints have been, and how you're feeling? There are so many who have horror stories, but I'm scared and wish to hear good things (if there are any). Please help with your response. Thank you.
I was apprehensive before starting anastrazole, but have found it to be nearly symptom free. Was 62 at diagnosis. Hit a deca scan and have slight osteopenia. Had achy joints at the 3-6 month mark, but then resolved. I’ve been an avid runner and gym enthusiast since college so that may be helping. Also, I didn’t really have menopause symptoms when went through it. I’ve been hopeful in taking anastrazole knowing it’s going to be a long treatment. When i take it I have it framed in my mind as being a little insurance policy against recurrrence. I’ll be thinking of you and wishing you a smooth adventure with it too! 😊
😂@@LindaLopez-i3r
I read your story and was very surprise by similarity to mine.I have one question to you,are you receiving bisphosphonates.I was offered one with DEXA T minus 1.2.I refused to take this drug and I can't stop worry about progression to osteoporosis.
I’ve asked my oncologist about the need for bone strengthening medication - asking if it’s better to be proactive. Her view is I only slightly have osteopenia and we don’t know it will progress. I will have my next dexa scan in Dec and we’ll compare to the previous. I prefer regular exercise keeping my bones strong if that will work versus a medication that will also bring side effects. I’ve asked about Zometa and Prolia specifically.
Hi, thanks for your videos 🥺. My mom has T1N1M0 HR+HER2- breast cancer, I’m doing a lot of research to explain her all reports, she’s very worried about needing chemo, doctors said that It will be radiation only but it’s scary to not taking chemo with that positive lymph node 😔 unfortunately in my country is very hard to do genomic test like oncotype, what should we do?
Since genomic testing like Oncotype is hard to access in your country, it's important to rely on your medical team's expertise. They likely considered various factors, including your mom's overall health and specific cancer characteristics.
Can we take herbal drinks when still undergoing hormone therapy? Thank you.
No the same dr said not to take during alopatyy treatment only greens fruits turmaric just punch in chilli powder added in foods nt more nd exercise
In general, avoiding St. John's wort in people on endocrine therapy is the only restriction you may hear about.
Hello dr. harmone therepy can kill remaining cancer cell in the body?
Hormonal therapy is designed to target remaining cancer cells that are hormone receptor-positive and can help prevent recurrence. It's an important part of treatment for many breast cancer survivors.
Hello Dear Dr. Griggs,
My mother age is 65 years old
Dcis: present
Size of largest dcis foci: 2mm
Type: micropapillary, cribriform, papillary, solid
Nuclear grade: grade3, marked nuclear pleormorphism
Impression:
Invasive ductal carcinoma,NST,grade2
All 4 node nagative
Margins: deep resection margin is 3 mm away from tumer. all other resected margins are free of tumer
Pathological stage: pt2Nsn(0)mx
Tumer size: 3.2×2.8×2 c.m
Tumer focality: unifocal
Histological grade: grade2,score7
Strongly er+ (100%), pr- (0), her2 +1(nagative)
Canasst oncostem low risk score is 9.9
Dear Dr. Griggs Please tell me which type of bc is this? Reqiurement of chemo or not i am in confusing situation please help me😢
Thanks for writing. Your mother is fortunate to have you looking out for her. This cancer would be classified as a Stage II infiltrating ductal carcinoma with DCIS present in the tumor. For our other viewers, OncoStem is a genomic assay that analyzes biomarkers in the tumor tissue sample using its own algorithm to determine a risk score. This risk score predicts the likelihood of cancer recurring within 5 years post-surgery. Based on the risk score, patients are classified as "low-risk" or "high-risk" for recurrence. In general, regardless of the assay, people with tumors classified as low risk do not benefit from chemotherapy. Of course, each person's situation is unique, and her doctors and she should discuss the results and their recommendations. We hope this is helpful.
Is N1mi early?
Yes, N1mi is considered early and refers to a minimal spread of cancer to lymph nodes, typically microscopic. It often indicates a relatively low level of lymph node involvement, but your doctor can give you a full picture based on your specific case.
If having high estrogen in the body causes breast cancer, why is that women are not tested for high estrogen besides a yearly mammogram
So this is interesting…high estrogen levels in the body do not cause breast cancer. That is, drawing blood levels of estrogen would not identify people at higher risk. Once breast cancer has been established, however, blocking estrogen from getting to any breast cancer cells is an effective therapeutic strategy. One link between breast cancer and estrogen is that prolonging estrogen exposure (by taking estrogen replacement therapy for many years) can increase the risk of breast cancer somewhat.
@@yerbba thank you for replying. Hope soon there will be a cure for cancer or at least a clear answer what causes cancer. 🙏