Treatment Options for HER2+ Breast Cancer: A Comprehensive Guide

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  • เผยแพร่เมื่อ 20 ต.ค. 2024

ความคิดเห็น • 53

  • @BL-f4b
    @BL-f4b 2 หลายเดือนก่อน +2

    I am a first time commenter but faithful follower on my two year triple positive sentinel node positive BC journey. I am grateful to have tolerated my year's treatment with Phesgo (Herceptin and Perjeta) well and am currently having no issues with Letrozole. Nerlynx was my nemesis as I had severe GI issues along with muscle spasms and deep fissures in my fingers. At 74, I chose to stop the kinase inhibitor to preserve my quality of life and ability to take care of an elderly spouse. My oncologist was supportive and is great ( but time stretched). This 40 year retired RN appreciates your kindness and thorough explanations Dr. Griggs. You obviously have the heart for your work.

    • @yerbba
      @yerbba  หลายเดือนก่อน +1

      Thank you for sharing your journey and for your kind words. It sounds like you've made some thoughtful decisions to balance treatment and quality of life, especially given the challenges with Nerlynx (for our other viewers, this is neratinib, an oral small molecule directed at the HER2 protein). Your experience as a retired RN gives you unique insight, and it’s wonderful to hear that your oncologist is supportive of your choices. We're glad to hear you're doing well on letrozole, and wish you continued health and strength as you move forward.

  • @juanitagee9511
    @juanitagee9511 2 หลายเดือนก่อน +2

    Dr. Griggs ~ thank you for all the knowledge that you share with us. You're the BEST!♡♡

    • @yerbba
      @yerbba  2 หลายเดือนก่อน +1

      You're the best! Thank you for being part of our community.

  • @ShitalNG
    @ShitalNG 2 หลายเดือนก่อน +1

    Thank you Dr. Griggs! Your videos are always very informative.

    • @yerbba
      @yerbba  2 หลายเดือนก่อน

      Thank you for the positive feedback! We appreciate your support.

  • @naththomas9946
    @naththomas9946 2 หลายเดือนก่อน +1

    Thank you, Dr. Griggs, for your informative advice.

    • @yerbba
      @yerbba  2 หลายเดือนก่อน

      Thank you for being part of the Yerbba community!

  • @jjp897
    @jjp897 14 ชั่วโมงที่ผ่านมา

    Hi Doctor i just diagnosed lobular cancer lymph node not involved. Tumor lessthan 4 cm , scheduled me for surgery . Whats your recommendation please let me know
    Thanks

  • @sand3882
    @sand3882 4 วันที่ผ่านมา

    I'm a new commentor today, too...I think. I certainly do have chemo brain. Sadly, I felt I was slipping considerably even before my surgery. I'm in my mid 60s. I don't know where to put my question. I hope you will read and can address it. I have chemo fog...did I say that earlier...🙄? I have a dandy case of neuropathy, mostly in my hands and feet up to right above my knees. Btw, I have HER2+...or, hopefully, had. Two trips by ambulance with multiple days in the hospital at treatments 4 and 6. Dr. told me at 4, I may not be strong enough to finish. Wasn't a super fan of my Doc. She is from another country, and I have difficulty understanding her sometimes. When I ask her to repeat something, she often gets frustrated. Awkward! Anyway, in a real Hallmark moment, with tears in my eyes, I said to her...Don't give up on me. She looked at me like a deer in the headlights for a moment, then gave me an awkward couple of pats on my shoulder and said...I won't give up on you. Sheesh. I'm so sorry I'm rambling. MY question is after losing about 50 lbs from 190...everything tasted like burnt metal so I couldn't eat, they told me to eat anything I wanted...pizza, ice cream, etc. I didn't ask them to repeat that as I was already out the door to pick up a pizza. Now I have gained about 20 lbs back and it seems I have one huge "chemo belly". They don't tell us about that either. If this thing doesn't get smaller soon, someone is going to throw me a baby shower! Help! Btw...I understand kind of what it is and what caused it but can't figure out how to get rid of it. Hope you see this. Love your style of teaching. Very conversational. Keep it up!

  • @iconic1758
    @iconic1758 25 วันที่ผ่านมา +1

    Is there any alternative treatment available for her2 positive tumors. I'm asking this because phyllodes tumor is highly resistant to conventional chemotherapies so doctors have just operated my mother

    • @yerbba
      @yerbba  7 วันที่ผ่านมา

      Phyllodes tumors are indeed relatively resistant to conventional chemotherapy, but the prognosis is generally excellent even without systemic treatment. It’s always a good idea to discuss with your oncologist if there are clinical trials or emerging treatments that could be worth exploring in your mother’s case.

  • @mariaesterdeleonguerrero9971
    @mariaesterdeleonguerrero9971 2 หลายเดือนก่อน

    This is my first time to comment. I just finished my 3rd cycle out of 6 cycles. Just recently I stumbled and I am very happy to subscribe to your channel. It really helped me how you explained things step by step. Thank you for making this video. 🙏🏼❤️‍🩹❤️

    • @yerbba
      @yerbba  หลายเดือนก่อน +1

      Thank you so much for taking the time to comment, and welcome to the Yerbba community! We’re glad our videos have been helpful to you as you go through treatment. We’re here to support you every step of the way.

  • @samanthaesra4035
    @samanthaesra4035 หลายเดือนก่อน +1

    Dear Doctor. I have been diagnosed with HER2 positive in my left breast with an aggressive tumor.
    Plus I have HER2 neg in my right breast. How is it even possible ? How will my oncologist treatt me ? I'm on the Red Devil at the moment.
    I am confused.
    I'm under state care in South Africa.

    • @yerbba
      @yerbba  25 วันที่ผ่านมา +1

      Thanks for sharing your story. It's important to differentiate a tumor that is "aggressive" in the pathology report from prognosis. Chemotherapy is highly effective along with anti-HER2 therapy (e.g., trastuzuamb) in tumors that are called "aggressive" by physicians. It is possible indeed to have two tumors, one in each breast, and they can be similar or completely different from one another. The "red devil" has a terrible name, doesn't it? It's also extremely effective in treating breast cancer. Keep coming back here for our videos and for the Yerbba community. We are wishing you the best as you progress on your treatment.

    • @samanthaesra4035
      @samanthaesra4035 25 วันที่ผ่านมา

      @@yerbba thank you Dr.

  • @samanthaesra4035
    @samanthaesra4035 หลายเดือนก่อน

    Thank you Doctor for teaching us.

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Thank you for watching!

  • @mezhini
    @mezhini หลายเดือนก่อน

    You are posting lastest updated videos. Great information sharing. Please arrange to provide your personalised report for Indian patients also. India , the most populated country in the world with substantial Breast cancer patients. Or please open an Indian branch in India

    • @yerbba
      @yerbba  25 วันที่ผ่านมา

      Thank you for your feedback! While we’re glad you find the videos helpful. Unfortunately, we currently cannot offer personalized Yerbba reports beyond the U.S. However, we hope to continue expanding in the future to reach more people globally.

  • @edenetorne6987
    @edenetorne6987 หลายเดือนก่อน

    I am HER2 positive and will have my last 2 trastuzumab treatments to complete 18 cycles. After these Are there other treatments I will have to undergo? Based on my recent breast lungs and whole abdomen ct scan/ultrasound the results are all very good. Thank you so much for all your very informative videos.

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Congratulations on nearing the completion of your trastuzumab treatments! After finishing trastuzumab, your oncologist will guide you on whether any additional treatments are necessary, but it sounds like you’re on a good path.

  • @swetaasinhaa
    @swetaasinhaa หลายเดือนก่อน

    My mom was diagnosed with Breast cancer 3 years ago Her2 positive with positive lymphatic node,she has undergone 6 cycle Chemotherapy, 17 target therapy, surgery and radiation. After 3 years now she found a lump in one of her lymph nodes and the same lymph node 1 cm in the neck was positive earlier as well. We are getting her biopsy done today. Could you suggest best line of treatment for her. How does people respond in such cases?

    • @yerbba
      @yerbba  25 วันที่ผ่านมา

      We're sorry to hear about your mom’s recurrence. In cases like this, the next steps depend on the biopsy results. If this is a recurrence of the cancer and if the cancer is still HER2-positive, further targeted therapies, such as trastuzumab (Herceptin) or pertuzumab, may be recommended. Chemotherapy or radiation might also be considered depending on the extent of the spread. Every case is different, but many people continue responding well to treatment even after recurrence.
      If you're in the U.S., we encourage her to visit Yerbba.com to learn more about her personalized treatment options. Each Yerbba Report provides a comprehensive view of the diagnosis, ensuring that she's aware of all possible treatments, including those that may not have been mentioned by her doctor, and explains why each treatment option was personalized to her specific tumor characteristics and health needs.

  • @Chakri-bc2jd
    @Chakri-bc2jd 2 หลายเดือนก่อน +1

    Hi doctor ,
    There is said to be a tablet from India called ' r+cu'
    Which is "resveratrol and copper" and is said to decrease reccurance chance by 40 % and eliminate side effects of chemo,
    Please please can you tell about it 🙏

    • @yerbba
      @yerbba  หลายเดือนก่อน

      It's important to approach claims like these with caution. There's no strong scientific evidence to support that "r+cu" or similar supplements can reduce recurrence by 40% or eliminate side effects of chemotherapy.

  • @SofiaAhmad-rp8sm
    @SofiaAhmad-rp8sm 2 หลายเดือนก่อน +1

    I diagnosed breast cancer stage 3 Her2 positive.

    • @neshatkoly7501
      @neshatkoly7501 2 หลายเดือนก่อน +1

      me too treatment is going on

    • @ASH-T786
      @ASH-T786 2 หลายเดือนก่อน +1

      I just finished my treatment for stage 3 her2 positive breast cancer 🤞 just had my last infusion of tragerted therapy hopefully my next oncologist appt they say I am in next stage and my cancer is in remission.
      Good luck with your treatment ❤ praying for you all

    • @yerbba
      @yerbba  หลายเดือนก่อน +1

      We hope you found the video helpful. The Yerbba community is here for you every step of the way.

  • @This.is.amnaaa
    @This.is.amnaaa 2 หลายเดือนก่อน +2

    I am on kadcyla currently. Only last cycle 13/14 left. Cant wait for treatment to end so i can plan a family. I have a question to cover for your next video. (Sorry for spamming as ive asked this before).
    The biggest purpose of the breasts are to feed a baby but no video covers in detail about women breastfeeding after cancer treatment.
    I am a 31yo stage 2, grade 3 her2+ hr- survivor and i had lumpectomy with chemo and radiation on my right breast. Currently on kadcyla. My surgeon told me if i have a baby now, i would have to "dry out" both my breasts so i dont get mastitis and yet the research says to breastfeed after treatment to reduce chances of recurrance. Please can you highlight complications of breastfeeding in detail in your next video? Thanks.

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Thank you for your question, and congratulations on nearing the end of your Kadcyla treatment! Breastfeeding after cancer treatment is an important topic, and we appreciate you bringing it up again. While our videos are already recorded, we’ll definitely add this topic to our list for an updated version. In the meantime, feel free to check out our existing video for more insights: th-cam.com/video/QmaqRgr8JVI/w-d-xo.html. Thanks for your thoughtful question, and we wish you the best as you plan for the future!

  • @Barbara-ex3ge
    @Barbara-ex3ge 2 หลายเดือนก่อน

    Thanks for another easily understood and empathic video. A question - I have been successfully treated for HER 2 breast cancer (chemotherapy and surgery followed by transtuzamab) and the sentinel node biopsy was negative. As I have had a double mastectomy (the first in 2015 for wide spread DCIS) can cancer reoccur in my breast (or elsewhere)?

    • @yerbba
      @yerbba  หลายเดือนก่อน +1

      Thank you for your question and your positive feedback. After a double mastectomy and successful treatment, the risk of recurrence in the area where your breast tissue was is extremely low. Even after treatment, it is possible that cancer can recur in other parts of the body. The risk of recurrence with HER2-positive breast cancer decreases over time, however.

  • @kathyspencer3292
    @kathyspencer3292 หลายเดือนก่อน

    It's been 3 years since I had a tram flap surgery for my breast cancer. I had radiation, chemotherapy and now on 8 years of hormone therapy. Two months ago, I noticed a sore spot on my back. Jumping ahead to today, I now have nerve pain over 60 percent of my body. Gabapenten is not working. No one seems to know why. It is debilitating. Has anyone else had or heard of this? Does anyone have any idea what could be causing this?

    • @yerbba
      @yerbba  หลายเดือนก่อน

      This sounds incredibly challenging. While we haven’t heard of this exact situation, it might be related to nerve damage from surgery or treatment. It’s important to keep pushing for answers-maybe see a neurologist or pain or palliative care specialist for more insight. It's also possible that others here in the Yerbba community may have heard of this phenomenon. We hope you find relief soon.

  • @zenetcenojas5279
    @zenetcenojas5279 2 หลายเดือนก่อน

    I was diagnosed stage1a, her2 negative.

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Thank you for sharing. You might find our video about HER2-negative breast cancer helpful. You can watch it here: [th-cam.com/video/VeLxQzKuGh0/w-d-xo.html].

  • @bhanumathikalyanasundaram.4930
    @bhanumathikalyanasundaram.4930 2 หลายเดือนก่อน

    Please clarify whether cancer patients can go for keto diet. I've been seeing videos being promoted by a certain Dr.Is it safe??Thanks a lot for all your informative videos. 👌 👍🙏🙏

    • @yerbba
      @yerbba  หลายเดือนก่อน

      We don’t recommend the keto diet in general unless you're under the supervision of a physician or dietician. We cover some of this in our video here: [th-cam.com/video/GoKaoWHgqU0/w-d-xo.html].

  • @JackiePorter-Smith
    @JackiePorter-Smith หลายเดือนก่อน

    Are HER2 Positive and HER2 Enriched the same? Do you have content related to HER2 Enriched breast cancer? Thank you.

    • @yerbba
      @yerbba  25 วันที่ผ่านมา

      HER2-positive refers to breast cancers overexpressing HER2 protein or gene, diagnosed by standard tests. HER2-enriched is a molecular subtype identified by gene expression profiling. Not all HER2-positive cancers are HER2-enriched. HER2-positive guides treatment, while HER2-enriched is mainly used in research and may indicate better response to HER2-targeted therapies.

  • @brendaillig-cg9xw
    @brendaillig-cg9xw หลายเดือนก่อน

    AFTER traztuzmab is finished after 1 year, then what? What keeps HER2 from growing again

    • @yerbba
      @yerbba  หลายเดือนก่อน

      After completing a year of trastuzumab, your medical team will closely monitor your health with regular physical examinations and a careful history of any symptoms you may have. The main goal of trastuzumab is to reduce the risk of recurrence. If your tumor was hormone receptor-positive, you are likely to be offered endocrine therapy (also called hormonal therapy). Also, in a large clinical trial, one year of traztuzumab was as effective as two years of treatment, and of course, avoiding overtreatment is important.
      If you're in the U.S., we encourage you to visit Yerbba.com to learn more about your treatment options. Your Yerbba Report provides a comprehensive view of your diagnosis, ensuring you're aware of all possible treatments, including those that may not have been mentioned by your doctor, and explains why each treatment option was personalized to your health needs. You may also find our video on why scans are not done to be helpful: th-cam.com/video/ScGAUNn-N1A/w-d-xo.html

  • @stitchywiggles
    @stitchywiggles 2 หลายเดือนก่อน

    Thank Doctor.

    • @yerbba
      @yerbba  2 หลายเดือนก่อน

      Thank you for watching!

  • @elsatravisano
    @elsatravisano 2 หลายเดือนก่อน

    What are treatment alternatives for HER2 positive if one was unable to tolerate Herceptin and Perjeta (heart ejection fraction issues)?

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Options may include different targeted therapies, potentially in combination with other treatments like chemotherapy or hormonal therapy, depending on your specific situation. If you're in the U.S., we encourage you to visit Yerbba.com to learn more about your treatment options. Your Yerbba Report provides a comprehensive view of your diagnosis, ensuring you're aware of all possible treatments, including those that may not have been mentioned by your doctor, and explains why each treatment option was personalized to your health needs.

  • @JackiePorter-Smith
    @JackiePorter-Smith หลายเดือนก่อน

    My biopsy is 2cm lesion infiltrating duct carcinoma grade 3 no lymphovascular invasion detected. I have been informed by oncologist it is HER2 enriched breast cancer stage 3. My lymph nodes were not biopsied but described on mammogram report as muliple hypoechoic left axillary lymph nodes measuring 7 and 9mm. Can they be sure without a biopsy of the lymph nodes just by looking at mammo and ultrasound images? I am to get chemo every 3 weeks for 6 months, then lumpectomy and lymph node removal, radiation for 3 weeks, then estrogen suppression meds. I was hoping lymph nodes not involved and could have a mastectomy and avoid radiation. If I have mastectomy instead of lumpectomy will this reduce the amount of radiation I get, even if lymph nodes are involved? I appreciate any clarity you could bring as I consider having mastectomy instead.

    • @yerbba
      @yerbba  หลายเดือนก่อน

      Thanks for writing. In people with Stage III (3) breast cancer, radiation therapy will be indicated even after mastectomy. Mastectomy may reduce the amount of radiation needed, but if lymph nodes are involved, radiation is often still recommended. It’s important to discuss all options with your oncologist to make the best decision for your situation.
      If you're in the U.S., we encourage you to visit Yerbba.com to access personalized treatment options and learn more about diagnosis. Your Yerbba Report provides a comprehensive view of all possible treatments, including those that may not have been mentioned by your doctor, and explains why each treatment option was personalized to your health needs.

  • @iconic1758
    @iconic1758 25 วันที่ผ่านมา +1

    Are you an oncologist?

    • @yerbba
      @yerbba  7 วันที่ผ่านมา

      Yes, Dr. Jennifer Griggs is a renowned breast cancer oncologist with extensive experience in helping patients navigate their journeys and treatment decisions.