Revealing the mysteries of pharmaceutical co-crystals
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- เผยแพร่เมื่อ 28 ก.พ. 2024
- Have you ever wondered what pharmaceutical co-crystal are? You know you have - that's why you're reading this description ;) Here we reveal their secrets; what they are, why they're useful and we look at some marketed products that contain co-crystals. And along the way I reveal whether the US FDA and I agree on whether salts are co-crystals!
These videos are the perfect accompaniment if you want to understand solid state forms;
What is a crystalline material? • What is a crystalline ...
What is an amorphous material? • What is an amorphous m...
What are hydrates and solvates? • What are (pharmaceutic...
The FDA definition of co-crystals can be found here;
www.fda.gov/media/81824/download
hi sir i am working on in-situ nasal gel preparation id appreciate your view on polymeric formulations for BCS class 2 drugs. LOVE YOUR WORK(I have just completed my bachelors)
Thanks for your kind words :) In general, I think polymeric formulations for BCS class 2 drugs are a good option - I am not a fan of cyclodextrins, so if a drug has poor solubility I think amorphous formulation, salts or polymers are the way forward.
😅 indeed Prof. I love the way you put it. "...not a fan of cyclodextrin..." I share your disliking. Thanks for an excellent channel and excellent videos.