*I was severely traumatized years ago as a teenage, got diagnosed with OCD. Spent my whole life fighting OCD. I suffered severe depression and mental disorder. Not until my husband recommended me to psilocybin mushrooms treatment. Psilocybin treatment saved my life honestly. 8 years totally clean, never thought I would be saying this about mushrooms.*
Congrats on your recovery. Most persons never realizes psilocybin can be used as a miracle medication to save lives. Years back i wrote an entire essay about psychedelics. they saved you from death bud, lets be honest here.
Hey mates! Can you help with the source? I suffer severe anxiety, panic and depression and I usually take prescription medicine, but they don't always help. Where can I find those psilocybin mushrooms?
Yes *Mr.Luccas024* ..Mushrooms are very medicinal. This is why anybody familiar with psilocybin and any other kind of fungi will tell you, "They are alive." They have a very ancient wisdom. To my experience, all mushrooms have always said, "Pay attention to your life. How you think, how you feel, and what will you do with the information that you always knew, but now are seeing in this point of view." This is why mushrooms are so respected in tribal cultures. This mental health treatment works for me too. Half micro doses do the trick for me. At least a few days at a time with lengthy time in between. Never addictive. Thank you for sharing this point!
I just tried MUSHROOMS for the first time. I felt as if i was in the center of the universe. I didn't go crazy after such an extreme experience. Totally got rid of depression, anxiety and illicit pill addiction.
Psilocybin saved me from years of uncontrollable depression, anxiety and illicit pills addiction. Imagine carrying heavy chains for over a decade and then all of a sudden that burden is gone. Believe it or not in a couple of years they'll all over for treatment of mental health issues.
Came to understand the basic interaction between antidepressants/psilocybin only and ended up learning a LOT more about how these substances work on our brains . thank you for this!
Thank you for sharing this video! EDIT** - and why I say thank you is because myself, I am on SSRI Fluoxatine 20mg, was scared shitless of SS and this video has totally confirmed in such a highly detailed and educational way the whole process of how both work with each other. I thank you so much, this will now help me complete my journey to ridding my life of anxiety for good. I have suffered for 20+ years aged 32
This is a great presentation on meds and their interactions with psychedelics, primarily mushrooms. Lots of practical information that can be used right away. The style of presentation was accessible and simplified what can be complex information. Highly recommended.
I swear : Sertraline changed my life in ways I hadn't imagined possible. At 46 y-o, I finally became my true self, without the constant and paralyzing anxiety triggers. But I feel like there'a still a part of me that hasn't fully blossomed, so I decided to try psilocybin microdosing, to hopefully improve my focus, memory function, creativity and to be less disorganized. Wish me luck!
Hello, Are you taking both Sertraline & Psilocybin at the same time? Or did you taper off the SSRI first? Would love to know,I’m in a similar situation
Your voice is so calming and smart. You explain things so well I've come to understand my depression and anxiety my mind so much better between lack of exercise and stressors in my environment, garbage I eat. I've been on celexa off and on for years I'm really looking forward to trying microdosing along with antidepressants I feel like the benefits are very strong.
Hello, you may no read this, but the way you expose, explain that systems, that functionality of our body it's amazing, very clear even for non english native. Thank and please keep it doing like your are doing it.
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to source here
I've been microdosing on the batch of mushrooms I got from one guy online for the last few months for depression and the results have been immeasurable. The world has beauty again whereas before it was grey and painful.
One of the uses of psychedelics is administering psilocybin to cancer patients, it allowed them to confron their mortality, remove fear and anxiety and to die with peace and equanimity. What a gift this is.
This is a great interview - very educational. I say microdosing is the way to go... I moved through the effects of meningitis with micro-dosing psilocybin. I am 69 now and super healthy with no medications at all. We grow our own now and microdose for evolutionary purposes. It's life's gift for us to get in balance and learn to 'know thy self'.
Two amazing women ! The host and the guest- thank you for caring and sharing this information- i was searching for answers for my 28 year old son who is on 150 mg Wellbutrin and started micro dosing last week. We feel relieved to know it’s okay for him to stay on his med while continue micro dosing. Thank you both again
@@Camilashein-xh4wwI was on 200mg Zoloft and started doing this. Eventually I got hooked on the combo because, for some reason, ssri’s and shrooms made me feel amazing. I felt as if all my problems went away, and after battling severe depression for the last 5 years due to my dads death, I felt as if I found the cure. I felt as if I could be truly happy. they drastically helped my life in the beginning. Long story short I started abusing them, was taking 2-5 grams of shrooms daily for the past year and a half. I started back doing music, became delusional as if I was going to make it and started to go crazy. I ended up getting sent to a psychiatric ward, PLEASE if your son has underlying bi polar do not have him mix the two. In my experience, the good and happy feeling I got was actually a manic episode. Today is 2 weeks that I’ve been off them and honestly, it hasn’t even been that bad. No withdrawals, maybe the occasional sadness but that’s it. I still want to do them, but it scattered my priorities and I learned a valuable lesson. In life you cannot cure depression. It’s apart of us as human beings. It’s best to use in moderation and not be an idiot like me. However I’ve always suffered from addiction. Not even hardcore drugs, just weed and bouts of Xanax here and there. Don’t do drugs kids
I messaged your clinic to inquire about a consultation for either professional or personal support. No response thus far, but you are one of two clinicians that is addressing this topic well and I’d love to connect.
@@jacquiedl - We didn't see anything come through. But please feel free to schedule a consultation! All appointments are made online anyway, at DrZelfand.com.
Effexor f’ed me up not only with the side effects while taking it (numb emotions, night sweats, decreased focus , and others), but also with major withdrawal issues. She makes it sound like ssri’s are harmless.
I’ve been on an MAOI (phenelzine) for 20 years and it has worked miraculously for my depression, even after 9 types of antidepressants plus 18 ECT treatments failed. Even though I’m not currently depressed, I’d really like to have a psilocybin experience for spiritual reasons. Has anyone here done psilocybin who’s chronically on an MAOI? If so, what dose of mushrooms did you take? I’m concerned about the blunting effects. Also, although this presentation says that there’s a risk of serotonin syndrome with MAOIs, I’ve read elsewhere that the risk is extremely low because psylocibin doesn’t increase serotonin in the synaptic cleft. Anyone have info on this?
Amazing Doctor. Not many know about 10% a month reduction of AD’s. Especially the SERT occupancy, the lower you get ex. 5mg Escitalopram to 0mg is NO, NO! 10% a month from 5mg to 0.02mg is the way to go. I know it will take years to come off this but is a safe way to avoid withdrawals. You can try every 3 weeks and do twice, if no withdrawals...try every 2 weeks and do it twice. If no withdrawals or minimal, you can do 10% a week reduction and you will be out of the meds faster. Good luck! No rush, do it S L O W!
Thank you for this, I started by going down to 1/2 an ad but awful withdrawal. It’s hard to tell if the psilocybin is working while trying to get off venlafacine 75mgs :(
@@teresaring8049 I’ve been tapering off venlafaxine 75 mg and I want to try mushrooms for the first time I’ve been doing the 10% drop counting the beads inside and I really haven’t had any side effects yet
I was hit by a drunk driver back in 1984. I was abused by alcoholic family. I have been traumatized when my father beat my mother in front of me when I was 2. The drunk driving accident caused nerve damage left side, bones through my skin, severe head injury, along with all the physical and emotional abuse Ive had over 40 years.. I started micro dosing several days ago.. .15 g. I feel different.. No negative thoughts, depression, anxiety. I need to do this consistently.. Somebody PLEASE help me feel normal.. PLEASE.
I can't find a source anywhere for any good psychedelics in my area, I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance, I felt free,the only high or euphoria was from the relief of my vices being released, that's exactly what it did
Mushroom completely turned my life around and my anxiety and panic attack disappeared and my personality changed into a much more generous loving person
I am currently on Auvelity and prozac and I took 800mg of psilocybin last night. The effects were subtle and mild, more like a buzz than anything else. Today I feel alot happier than normal and am wondering if this is placebo effect or could the small amount I took actually have had some benefit?
Thank you, this was very informative. I'm a long-time user of escitalopram and I'm looking into the possibility of tapering the dose while I am micro-dosing with psilocybin. I have tried "cold turkey" and thankfully I had no real negative side-effect besides vertigo during the day. I am back on half the dose I used to be, and I function quite well, similarly to the original dose. You have given me great insight into how an SSRI works in the brain and what the long-term effect is. Also, I have learnt what the negative effect may be to quitting cold turkey, so also a big thank you for that.
@@rickyjenkins5501 just been notified that lexapro blocks most of the effects of microdosing. But can be helpful when tapering off, and could have a positive exp some time after getting off the lexapro.
@@danselzer I tried 3.5g while on Lexapro and mostly experienced a little bit of weird mental discomfort. I tried it again last year 2 months after going cold turkey off Lexapro, did 4g and it WORKED lol. It would have been a very positive experience if I hadn’t done it by myself with no prior experience.
This was very informative. I take medication for bipolar mood disorder. They include Quetiapine (Dopaquel 300mg at night), Escetalopram (Lexamil 10mg), Lamotragine (Epitec 100mg twice daily). I started taking a new psilocybin capsule yesterday and felt nauseas, had severe headache, temperature rise and faster heartbeat. I find the SSRI alone does not relieve my depression and that's why I want to supplement with mushrooms. But it is not making me feel good. Maybe my brain still needs to get use to it or I should lower the dosage. Anyway, thanks for making this video. I also need Dormonoct (Benzodiazepine) to sleep at night. My dreams are more vivid and I often wake up from them so I have disturbed sleep. I will keep experimenting with all the tools I have. Thanks again.
I'm on anxiety medication and have been trying to get high on shrooms... doesn't seem to work as apparently the meds kill the trip.. any suggestions on how to bypass this problem... maybe if I stop taking them for a couple days before
This is the exact question I came here to have answered. Just recently started Cymbalta and wanted to know if it was safe to continue microdosing! Thank you for your personal experience
Thanks for answering so many questions! I’m on fluoxetine 20 mg and was afraid to try psilocybin because of serotonin syndrome. I’ve been up to 40mg on the fluoxetine, but began to feel too numb. Def want to try the shrooms ❤
Get off the Prozac. Decreases your lifespan by 10 years due to cardiogenic effects. You're worth more than an early death caused by big pharma's greed. Definitely try different approaches. SSRIs will give you rebound depression. Really bad. Hope you make it.
Hello doctor is there any supplement for of this miracle mushroom and dont know where can i get a trusted source thsnks for the podcast ibdont take amy meds but i have severe anxiety snd attacks every day thanks
Thanks so much. This has cleared up so much misinformation about how tryptamines function versus Antidepressants. The understanding of how psilocybin functions at the synaptic cleft is a crucial understanding. I was one of those who, four years ago, got off my 3 meds, and went to Costa Rica to do Ayahuasca. Then we were up sold to come back 3 months later, this was Rythmia , and then the crisis came while I was there. Psilocybin is a different animal than Aya. Thank you for the knowledge.❤️
Hi, did Ayahuasca work and make you not need your meds anymore? I'm just cautious about tapering off my meds in case Ayahuasca doesn't do anything. I've heard it can be transformative or not do much.
What an excellent and helpful video!! I’d love to try psylicibin therapy but haven’t found a local place to do it yet. In the meantime I’m happy to know that using shrooms recreationally isn’t terribly dangerous with my current meds. Thanks so much for sharing your knowledge in an easy to understand and straightforward way!!! 🙏🏻
You are so informative and I’m so glad that you understand the 10% method and the avoiding of protracted withdrawal. I feel like I can put a lot of trust in you and I’ve never tried mushrooms or anything so I am eager to get some benefit from this.
Hi Erica, I’m interested to know what the conflicts or benefits would be taking psilocybin while on PDE4 inhibition medication. As I understand it PDE4 inhibition medication is mainly an anti-inflammatory mode of action drug. Thanks Dane Poulsen
This is fantastic. I have been waiting for there to be more attention brought to this issue. I would love to have a consultation with you around some questions. I will try to find your contact information and see if this is possible.
@@drzelfand I had written a detailed message asking about whether I should request for personal or professional. My inquiry is hybrid. Both Professional and Personal and I did not want to irritate you with requesting a professional consult and then share some personal experiences.
Thank fo this good information. One question : before night, I take 50 mg Trazodone. Is it contraindicated with psilocybin? Thank to all of you during the day.
Super, super, super informative! Thank you :) Rarely do I sit through long videos, and I don’t even consider myself to be too science oriented. I’m trying to do a lot of research in order to make a safe and informed decision, and this helped a lot. I love the use of a powerpoint too (I’m a visual learner). It made it so much easier to understand, and if it was just talking the whole time I would have clicked off. Great stuff ♥️
Thank you so much for this informative lecture! I found out the hard way not to stop antidepressants abruptly. And I am one of the lucky people who can trip on magic mushrooms and no increase in dosage needed even on an SNRI antidepressant.
Hi Diana, i am on SNRI (Efexor/Venlafaxine) since 9 years and i am wonder if i can use mushrooms as i am suffering again from a severe depressive episode. I tried so many AD the last 20 years but nothing really helped. can you share your experience with using mushrooms whole on SNRI? For a pity i can taper them as they cause bad withdrawal, I hope to improve under mushrooms and to be able to get rid of this poison one day. thanks alot, Hasna
This is such good content. Thank you. I have a question for you. A friend of mine (lol) started taking psilocybe mushrooms for the first time, including a few macrodoses and regular microdoses while on an SNRI. My friend started having vivid dreams every night which has never been the norm. Even after discontinuing the mushrooms for a week, the dreams persist. It's not a negative thing, but very interesting. In relation to your comment about remembering dreams being a sign that you can taper off SSRIs more quickly, what could be a cause of the change in dreams? Thank you again, this info is indispensable!
Thanks SO much! This video was VERY informative and helpful. I've been prescribed a variety of antidepressants over the past few years, primarily because I am very sensitive to the side effect of 'nausea'. I just recently had a scope (upper and lower) which revealed I have chronic gastritis-undefined. Is this a result of antidepressant use? I'm currently taking 10 mg Trintellix. Will micro-dosing psilocybin help or harm? What dose of psilocybin would be a good starting place? Also, you mentioned a 'Jamaican' trip. Where can I get information regarding that experience? I go to Jamaica frequently and would be interested in learning more! Many thanks :)
This video contradicts what i know about tripping under SSRIs . Everybody says that they cannot feel anything at all if taking SSRIs and psilocybin. Even if thay ingest 40++ grams. So many studies confirm what I just wrote. So where is the truth? I don’t understand. I listen carefully to the dr in the video and she seems so convincing and convinced. Big big question mark ⁉️
I hope you can help. I want to try psilocybin, but I take 15 mgs of Trintellix, and 7.5 mgs of Remeron ( Mirtazapine) a day. Not SSRIs. Can I do psilocybin?
This is Nice. Actually there is this reputable shroom farm, where i сор exactly same package, dude got (Gummies shrooms & chocolate bar) from two weeks ago. Still on it
From my personal experience as an autistic that’s tapering off Zyprexa and Trintellix it’s recommended to do 1 gram doses once a day while you taper off your medication. You need a holistic psychiatrist.
If anti depressants were very effective pharma companies would lose out. Best to keep people using. I remember when I was using them if I went to the doctors complaining of no improvement in mood, they would say double your dose of anti depressants. And I even went back again after the dose was doubled, and they offered more. They literally made me worse. Pharmaceutical companies can’t patent and sell a mushroom, they also only need to be used once or twice properly too, unless you micro dose.
This was a very informative and easy to understand presentation, thank you for that. I would find it interessting to know the risks and benefits of combining classic tryptamines (LSD, DMT, Psilocybin) with mood stabilizers. I'm taking valproate due to BPD. There are many controversial meanings when having bipolar and taking psychedelics.
One time when still in my teens I was able to use psilocybin. I am saddened that I never had an opportunity to use it again, nor did I have a prescribed opportunity. Where I live in North Carolina there is little hope that the doctors treating me will prescribe psilocybin for me. I have incredible difficulty stopping the use of cigarettes.
I've been talking desvenlafaxine for 3 years now im going to start tapering myself off. As i do so im going to take phylabcyben, so hopefully, i can get off it faster without going through the withdrawals.
Hi, thank you for the very informative video. It would be great if you covered a little more on SNRIs. I'm just a little confused by the notion that taking antidepressants can be healing, yet also after prolonged use it reduces receptors in the recieving neuron. That doesn't sound very healing :(
if you get your own genes tested, you can see if you have the HTR2A mutation that effects psychedelics, and interestingly...citalopram reduces it's expression even further, so if you have that g/g mutation, you probably need to consider if the antidepressant will surpress this seratonin receptor if you're also considering shrooms,. Not medical advice, but I think you're on to something
KBTV I wondered the same thing about the reduction in the receiving receptors, and it doesn't sound very healing to me, either. I would love to hear more about that. Like at what point of taking an SSRI does that happen (months? years?). And, after those are reduced, if you go off the SSRI will they regenerate?
You talked about Psilocybin MACRODOSING being safe with antidepressants. But what about MICROdosing? It was not brought up. I would appreciate some input. I am trying to taper off Cymb@lt@ and am having a very hard time. Thank you!
Are you switching to a new med? I'd bring it up to your psych. I am coming off cymbalta and going on Prozac. She gave me a schedule where I reduced cymb. And started Prozac. Haven't had any issues except a headache for a few days at beginning. Its different for everyone but slower the taper the less you will feel withdrawal.
Appreciate this. Been very curious/worried about microdosing while taking SSRIs. I've been nervous about SSRIs in general and have been sitting on a Lexipro prescription for a week. But this makes me feel far more comfortable and even hopeful that the two different methods may be supportive of each other in some ways. Though it does seem microdosing may not be effective [.15mg] when combined with the lexipro [5mg] so there may be some adjustments to be had there. I'm frankly not sure, beyond the first day, how much the microdosing has helped, though I've been very cautious with dosage and schedule so that may be part of it too. Regardless this is fascinating and hopeful! Thank you for your study and for sharing!
So how has your expreience been? I am on 10mg lexapro and I want to start microdosing. I'm in the early part of the video so I'm not sure what she says about SSRI's x microdosing. However, I gather from your post that you've starting dosing while on Laxpro. What have you experienced?
@@EdwardBose So I was microdosing before lexipro. I was afraid to start the medication so I wanted to give it a shot first. I'm on 5mg of lexipro. I've only been for a week and a half so far. I decided to wait until I adjusted before attempting to combine the 2. Sorry I don't have a practical response, but I do intend to give it a shot in a couple more weeks.
From my own personal experience with over 10 years of experience with trying to get off of various doses of celexa. I had the brain zaps, the nausea, the dizziness, everything. It was absolutely horrible and debilitating a lot of the time. I finally found a doctor, who was willing to help me taper down very very slowly, and I started taking the supplement Sam E while I continue to gradually taper. I had to taper down over the course of a year in order for me to finally be able to do it with very minimal side effects. That was about 10 years ago and microdose thing is much more studied now, and much more of a known thing. I had had experiences with psychedelics, but never in terms of using them as an antidepressant. Although in retrospect, they definitely did help me get through some major issues in my life. My main point here though, is that, if you have not yet started your prescription, I would wait. I would try microdose thing first and then if you’re still thinking, you really need the antidepressants then give them a try. I’m not a doctor, so I’m not going to say that this is medical advice or anything it’s just from my own personal experience I would strongly discourage anybody from ever starting to take anti-depressants of any kind ever unless all other options have been exhausted. They are a nasty medication. That very rarely actually helps people. In fact, the placebo groups in the studies they’ve done I’ve done just as well, if not better than the actual group taking the real medication
I’m loving this video and 3/4 of the way through it and on venlafaxine and I want to take my first mushroom experience. Does this video hopefully tell us how much a good milligram for first dose should be?
I am taking Wellbutrin (Buproprion) and I wonder what is the interaction between psilocybin and wellbutrin? Should I also take larger quantity of psilocybin because I am taking wellbutrin?
Just a heads up for everyone looking for medical advice here: I couldn’t verify Dr. Zelfand’s licensure on the Oregon Medical Board license look up. It appears she is not a licensed physician. Erica if you read this - could you provide your license number? Everyone is free to seek treatment in the manner of their choice and I support people seeking naturopathic or minimal-intervention therapies first. However, if you are a neuroscientist or fellow medical professional looking for well-informed advice on the neurochemical interactions between SSRI’s and the agonist effect of psilocybin, seek it elsewhere.
In the beginning of the slides it says she is licensed as a naturopathic doctor. They don't emphasized in the video that she is not an MD or DO. The distinction is important. Also doesn't mean this information is useless though.
I was really hoping combining psilocybin and Trazodone (SARI) would’ve been discussed. It’s not an MAOI, but also not technically an SSRI. Can I take psilocybin if I stay on my current dose of 50mg of Trazodone per night (for insomnia)?
*I was severely traumatized years ago as a teenage, got diagnosed with OCD. Spent my whole life fighting OCD. I suffered severe depression and mental disorder. Not until my husband recommended me to psilocybin mushrooms treatment. Psilocybin treatment saved my life honestly. 8 years totally clean, never thought I would be saying this about mushrooms.*
Congrats on your recovery. Most persons never realizes psilocybin can be used as a miracle medication to save lives. Years back i wrote an entire essay about psychedelics. they saved you from death bud, lets be honest here.
Hey mates! Can you help with the source?
I suffer severe anxiety, panic and depression and I usually take prescription medicine,
but they don't always help. Where can I find those psilocybin mushrooms?
Yes *Mr.Luccas024* ..Mushrooms are very medicinal. This is why anybody familiar with psilocybin and any other kind of fungi will tell you, "They are alive." They have a very ancient wisdom. To my experience, all mushrooms have always said, "Pay attention to your life. How you think, how you feel, and what will you do with the information that you always knew, but now are seeing in this point of view." This is why mushrooms are so respected in tribal cultures. This mental health treatment works for me too. Half micro doses do the trick for me. At least a few days at a time with lengthy time in between. Never addictive. Thank you for sharing this point!
How do I reach out to him? Is he on
*what app*
I just tried MUSHROOMS for the first time. I felt as if i was in the center of the universe. I didn't go crazy after such an extreme experience. Totally got rid of depression, anxiety and illicit pill addiction.
Psychedelics should only be used with great care and respect, I would love to feel same man , how do you source em
dr.perryshroom is your guy. Got all kinds of psychedelics stuff. Guided me through my first ever experience
YES, dr.perryshroom. There's a lot of potential in psychedelics
Nature is magical and healing. what a beautiful experience 🍄
hm. Can dr.perryshroom dispatch to me in LA?
Wow, could listen to this woman all day!
Psilocybin saved me from years of uncontrollable depression, anxiety and illicit pills addiction. Imagine carrying heavy chains for over a decade and then all of a sudden that burden is gone. Believe it or not in a couple of years they'll all over for treatment of mental health issues.
LSD and psilocybin did it for me depression is gone completely😋😋
*Does anyone know any good source. I put so much on my head and it's affecting my mental health. I'll like to try shrooms*
**Yes dr.henryshroom is my shroom vendor and mycologist.**
*Is he on insta?*
Yeah #dr.henryshroom#**
Came to understand the basic interaction between antidepressants/psilocybin only and ended up learning a LOT more about how these substances work on our brains . thank you for this!
This is the best presentation on antidepressants I have ever seen! Thank you
Thank you for sharing this video!
EDIT** - and why I say thank you is because myself, I am on SSRI Fluoxatine 20mg, was scared shitless of SS and this video has totally confirmed in such a highly detailed and educational way the whole process of how both work with each other. I thank you so much, this will now help me complete my journey to ridding my life of anxiety for good. I have suffered for 20+ years aged 32
I’m on SSRI 150mg Effexor. I want to get off too!
We need more people in this world like you Dr. Erica Zelfand 😄.
This is a great presentation on meds and their interactions with psychedelics, primarily mushrooms. Lots of practical information that can be used right away. The style of presentation was accessible and simplified what can be complex information. Highly recommended.
I swear : Sertraline changed my life in ways I hadn't imagined possible. At 46 y-o, I finally became my true self, without the constant and paralyzing anxiety triggers. But I feel like there'a still a part of me that hasn't fully blossomed, so I decided to try psilocybin microdosing, to hopefully improve my focus, memory function, creativity and to be less disorganized. Wish me luck!
Same! I hope you have a wonderful experience.
That medication made me sweat and feel awful
@@ruthw7129 Thx! So far so good on 125 mg !
How are you getting on with microdising?
Hello, Are you taking both Sertraline & Psilocybin at the same time? Or did you taper off the SSRI first? Would love to know,I’m in a similar situation
🚨 beware of Instagram scammer bots talking to each other in the comments. They are in all videos related to psychedelics. Please report them to TH-cam
Your voice is so calming and smart. You explain things so well I've come to understand my depression and anxiety my mind so much better between lack of exercise and stressors in my environment, garbage I eat. I've been on celexa off and on for years I'm really looking forward to trying microdosing along with antidepressants I feel like the benefits are very strong.
21:44 lifted me out of a Depression.
Hello, you may no read this, but the way you expose, explain that systems, that functionality of our body it's amazing, very clear even for non english native. Thank and please keep it doing like your are doing it.
Psychedelic’s definitely have potential to deal with mental health symptoms like anxiety and depression, I would like to try them again but it’s just so hard to source here
I've been microdosing on the batch of mushrooms I got from one guy online for the last few months for depression and the results have been immeasurable. The world has beauty again whereas before it was grey and painful.
One of the uses of psychedelics is administering psilocybin to cancer patients, it allowed them to confron their mortality, remove fear and anxiety and to die with peace and equanimity. What a gift this is.
Tripping and microdosing are not really bad but find a good mycologist Who will teach you the right things you need to know
How do I get them?
@alexmccole6925 I Came across some comments about Myco_sporres I must recommend he is good at what he does. And I highly recommend him
I'm so impressed with your presentation. Thank you for sharing this!
Dr Zilfand did a beautiful job presenting. I'm looking forward to following her!
This is a great interview - very educational. I say microdosing is the way to go... I moved through the effects of meningitis with micro-dosing psilocybin. I am 69 now and super healthy with no medications at all. We grow our own now and microdose for evolutionary purposes. It's life's gift for us to get in balance and learn to 'know thy self'.
This was an amazing presentation, thank you for sharing it.
Two amazing women ! The host and the guest- thank you for caring and sharing this information- i was searching for answers for my 28 year old son who is on 150 mg Wellbutrin and started micro dosing last week. We feel relieved to know it’s okay for him to stay on his med while continue micro dosing. Thank you both again
Everyday or once a week? How did you do it?
Could you tell us how much and how often? I am looking to do the same safely
@@Camilashein-xh4wwI was on 200mg Zoloft and started doing this. Eventually I got hooked on the combo because, for some reason, ssri’s and shrooms made me feel amazing. I felt as if all my problems went away, and after battling severe depression for the last 5 years due to my dads death, I felt as if I found the cure. I felt as if I could be truly happy. they drastically helped my life in the beginning. Long story short I started abusing them, was taking 2-5 grams of shrooms daily for the past year and a half. I started back doing music, became delusional as if I was going to make it and started to go crazy. I ended up getting sent to a psychiatric ward, PLEASE if your son has underlying bi polar do not have him mix the two. In my experience, the good and happy feeling I got was actually a manic episode. Today is 2 weeks that I’ve been off them and honestly, it hasn’t even been that bad. No withdrawals, maybe the occasional sadness but that’s it. I still want to do them, but it scattered my priorities and I learned a valuable lesson. In life you cannot cure depression. It’s apart of us as human beings. It’s best to use in moderation and not be an idiot like me. However I’ve always suffered from addiction. Not even hardcore drugs, just weed and bouts of Xanax here and there. Don’t do drugs kids
Thank you. This video is just what i was looking for!!
Thank you so much for posting this excellent discussion.
This is such a well-explained and informative video. I learned a lot about Psilocybin and Antidepressants just as the title promised. Many Thanks!
I got my stuff delivered discreetly by this mycologist whose get lsd, dmt, mushrooms and more
@pham_smart1
Dude is on telegram and Instagram
Great video, looked for something like this for a long time
Thanks for having me. There's so much more to say, but here's what we could do in an hour :-)
Question for Dr. Zelfand-You mentioned you like prescribing SNRIS over SSRIS. I was wondering why.
I messaged your clinic to inquire about a consultation for either professional or personal support. No response thus far, but you are one of two clinicians that is addressing this topic well and I’d love to connect.
@@jacquiedl - We didn't see anything come through. But please feel free to schedule a consultation! All appointments are made online anyway, at DrZelfand.com.
Can a person microdose psilocybin with viibryd?
Effexor f’ed me up not only with the side effects while taking it (numb emotions, night sweats, decreased focus , and others), but also with major withdrawal issues. She makes it sound like ssri’s are harmless.
I’ve been on an MAOI (phenelzine) for 20 years and it has worked miraculously for my depression, even after 9 types of antidepressants plus 18 ECT treatments failed. Even though I’m not currently depressed, I’d really like to have a psilocybin experience for spiritual reasons. Has anyone here done psilocybin who’s chronically on an MAOI? If so, what dose of mushrooms did you take? I’m concerned about the blunting effects.
Also, although this presentation says that there’s a risk of serotonin syndrome with MAOIs, I’ve read elsewhere that the risk is extremely low because psylocibin doesn’t increase serotonin in the synaptic cleft. Anyone have info on this?
Amazing Doctor.
Not many know about 10% a month reduction of AD’s.
Especially the SERT occupancy, the lower you get ex. 5mg Escitalopram to 0mg is NO, NO!
10% a month from 5mg to 0.02mg is the way to go.
I know it will take years to come off this but is a safe way to avoid withdrawals.
You can try every 3 weeks and do twice, if no withdrawals...try every 2 weeks and do it twice. If no withdrawals or minimal, you can do 10% a week reduction and you will be out of the meds faster.
Good luck!
No rush, do it S L O W!
Yes my own PCP I guess didn't know either. Learning late that just a primary is so not enough.
Thank you for this, I started by going down to 1/2 an ad but awful withdrawal. It’s hard to tell if the psilocybin is working while trying to get off venlafacine 75mgs :(
@@teresaring8049 I’ve been tapering off venlafaxine 75 mg and I want to try mushrooms for the first time I’ve been doing the 10% drop counting the beads inside and I really haven’t had any side effects yet
How did you use it? in a powedwr or tea form ,and where can i order some?
Wow that presentation was awesome! So informative & detailed. Answered a lot of my questions. Thank you sm!
I was hit by a drunk driver back in 1984. I was abused by alcoholic family. I have been traumatized when my father beat my mother in front of me when I was 2. The drunk driving accident caused nerve damage left side, bones through my skin, severe head injury, along with all the physical and emotional abuse Ive had over 40 years.. I started micro dosing several days ago.. .15 g. I feel different.. No negative thoughts, depression, anxiety. I need to do this consistently.. Somebody PLEASE help me feel normal.. PLEASE.
Best of luck with your healing
look up Michael Singer
Grow your own mushroom supply. Who's going to know 🤷🏼♀️
I can't find a source anywhere for any good psychedelics in my area, I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance, I felt free,the only high or euphoria was from the relief of my vices being released, that's exactly what it did
The psychedelic experience is temporary but many people have permanent results
Mushroom completely turned my life around and my anxiety and panic attack disappeared and my personality changed into a much more generous loving person
I got mine from @doctor_ mckenzie
I had 3.5 grams dried lemon tek most beautiful experience ever!!
Is he on on Instagram or what?
Excellent presentation covering an essential topic. Thank you Dr Z! 🙏🏻
Super helpful and Informative video thankyou so much.
I am currently on Auvelity and prozac and I took 800mg of psilocybin last night. The effects were subtle and mild, more like a buzz than anything else. Today I feel alot happier than normal and am wondering if this is placebo effect or could the small amount I took actually have had some benefit?
What a fantastic presentation...
Thank you, this was very informative. I'm a long-time user of escitalopram and I'm looking into the possibility of tapering the dose while I am micro-dosing with psilocybin.
I have tried "cold turkey" and thankfully I had no real negative side-effect besides vertigo during the day. I am back on half the dose I used to be, and I function quite well, similarly to the original dose.
You have given me great insight into how an SSRI works in the brain and what the long-term effect is. Also, I have learnt what the negative effect may be to quitting cold turkey, so also a big thank you for that.
Do you know if theres any interactioms between lexapro and microdosing mushrooms
@@rickyjenkins5501 just been notified that lexapro blocks most of the effects of microdosing. But can be helpful when tapering off, and could have a positive exp some time after getting off the lexapro.
@@danselzer I tried 3.5g while on Lexapro and mostly experienced a little bit of weird mental discomfort. I tried it again last year 2 months after going cold turkey off Lexapro, did 4g and it WORKED lol. It would have been a very positive experience if I hadn’t done it by myself with no prior experience.
Thank you I was so impressed with the wonderful info and the way in which you explain !! Excellent !!
Thank you for this presentation, the information has helped me immensely.
This was very informative. I take medication for bipolar mood disorder. They include Quetiapine (Dopaquel 300mg at night), Escetalopram (Lexamil 10mg), Lamotragine (Epitec 100mg twice daily). I started taking a new psilocybin capsule yesterday and felt nauseas, had severe headache, temperature rise and faster heartbeat. I find the SSRI alone does not relieve my depression and that's why I want to supplement with mushrooms. But it is not making me feel good. Maybe my brain still needs to get use to it or I should lower the dosage. Anyway, thanks for making this video. I also need Dormonoct (Benzodiazepine) to sleep at night. My dreams are more vivid and I often wake up from them so I have disturbed sleep. I will keep experimenting with all the tools I have. Thanks again.
I'm on anxiety medication and have been trying to get high on shrooms... doesn't seem to work as apparently the meds kill the trip.. any suggestions on how to bypass this problem... maybe if I stop taking them for a couple days before
I tried psilocybin once (like a year ago). It was a great experience! Definitely will try again!
Thank you so much for an in-depth video about this topic.
I am taking Cymbalta AND microdose and I love it, in fact I don’t even want to stop neither of them.
I am starting to microdose tomorrow and start tapering off desvenlafaxine wish me luck.
This is the exact question I came here to have answered. Just recently started Cymbalta and wanted to know if it was safe to continue microdosing! Thank you for your personal experience
What a great informative hour 👏
Very well presented and informative.
Thankyou for this ! Very informative
This was exciting and beautiful, thank you!
Thanks for answering so many questions! I’m on fluoxetine 20 mg and was afraid to try psilocybin because of serotonin syndrome. I’ve been up to 40mg on the fluoxetine, but began to feel too numb. Def want to try the shrooms ❤
Get off the Prozac. Decreases your lifespan by 10 years due to cardiogenic effects. You're worth more than an early death caused by big pharma's greed. Definitely try different approaches. SSRIs will give you rebound depression. Really bad. Hope you make it.
This is awesome! Thank you so much for sharing!
Great video, Is there any psilocybin-assisted therapy in Jacksonville Florida?
Get on with Dr. Charles popularly known as charlesmyco
Hello doctor is there any supplement for of this miracle mushroom and dont know where can i get a trusted source thsnks for the podcast ibdont take amy meds but i have severe anxiety snd attacks every day thanks
@Kennedytyler-t7r can you please let me know where is this farm I can't function much mentally and don't know where to go thanks
@Kennedytyler-t7r thanks I'm speaking with them RN very legit
Thanks so much. This has cleared up so much misinformation about how tryptamines function versus Antidepressants. The understanding of how psilocybin functions at the synaptic cleft is a crucial understanding. I was one of those who, four years ago, got off my 3 meds, and went to Costa Rica to do Ayahuasca. Then we were up sold to come back 3 months later, this was Rythmia , and then the crisis came while I was there. Psilocybin is a different animal than Aya. Thank you for the knowledge.❤️
Hi, did Ayahuasca work and make you not need your meds anymore?
I'm just cautious about tapering off my meds in case Ayahuasca doesn't do anything. I've heard it can be transformative or not do much.
What an excellent and helpful video!! I’d love to try psylicibin therapy but haven’t found a local place to do it yet. In the meantime I’m happy to know that using shrooms recreationally isn’t terribly dangerous with my current meds. Thanks so much for sharing your knowledge in an easy to understand and straightforward way!!! 🙏🏻
Thank you, great presentation. Still i must ask about bipolar disorder can we be treated?
You are so informative and I’m so glad that you understand the 10% method and the avoiding of protracted withdrawal. I feel like I can put a lot of trust in you and I’ve never tried mushrooms or anything so I am eager to get some benefit from this.
So do mushrooms work if you’re on a ssri like lexapro and if not how long after last does of ssri does it take for mushrooms to work?
I learnt a lot, thank you it's changed my point of view a bit. Take care
That would be most appreciated!
Thank you. This is immensely helpful.
Hi Erica,
I’m interested to know what the conflicts or benefits would be taking psilocybin while on PDE4 inhibition medication. As I understand it PDE4 inhibition medication is mainly an anti-inflammatory mode of action drug.
Thanks
Dane Poulsen
Link to dr.Malcolms video about Psilocybin-drug interactons, please? Thank you.
I currently taking Zoloft and Sereoquil. Can I experiment with mushrooms
Great video 🎉
Great video
I was able to overcome depression and anxiety which held me down for 3 years, all thanks to psychedelics, psilocybin mushrooms and LSD
Where can I get it, really difficult to locate here
@@Leonardo_559 dr.fselman
dr.fselman
Insta
Frierson selman
Useful, holistic, integrative approach!
Great presentation.
This is fantastic. I have been waiting for there to be more attention brought to this issue. I would love to have a consultation with you around some questions. I will try to find your contact information and see if this is possible.
Sure! I replied above, but will do so here as well. Visit my website to make an appointment: DrZelfand.com :-)
@@drzelfand I had written a detailed message asking about whether I should request for personal or professional. My inquiry is hybrid. Both Professional and Personal and I did not want to irritate you with requesting a professional consult and then share some personal experiences.
Thank fo this good information. One question : before night, I take 50 mg Trazodone. Is it contraindicated with psilocybin? Thank to all of you during the day.
I like to know about that
I have been in Trazodone for many years and have had no issues micro dosing.
Super, super, super informative! Thank you :) Rarely do I sit through long videos, and I don’t even consider myself to be too science oriented. I’m trying to do a lot of research in order to make a safe and informed decision, and this helped a lot. I love the use of a powerpoint too (I’m a visual learner). It made it so much easier to understand, and if it was just talking the whole time I would have clicked off. Great stuff ♥️
Thank you so much for this informative lecture! I found out the hard way not to stop antidepressants abruptly. And I am one of the lucky people who can trip on magic mushrooms and no increase in dosage needed even on an SNRI antidepressant.
Thanks for sharing this.
I would love to pick your brain about your experience.
You're very lucky, I'd love to pretend I'm not jealous :(
Hi Diana, i am on SNRI (Efexor/Venlafaxine) since 9 years and i am wonder if i can use mushrooms as i am suffering again from a severe depressive episode. I tried so many AD the last 20 years but nothing really helped. can you share your experience with using mushrooms whole on SNRI? For a pity i can taper them as they cause bad withdrawal, I hope to improve under mushrooms and to be able to get rid of this poison one day. thanks alot, Hasna
This is such good content. Thank you. I have a question for you. A friend of mine (lol) started taking psilocybe mushrooms for the first time, including a few macrodoses and regular microdoses while on an SNRI. My friend started having vivid dreams every night which has never been the norm. Even after discontinuing the mushrooms for a week, the dreams persist. It's not a negative thing, but very interesting. In relation to your comment about remembering dreams being a sign that you can taper off SSRIs more quickly, what could be a cause of the change in dreams? Thank you again, this info is indispensable!
I'd definitely like to know as well
Thanks SO much! This video was VERY informative and helpful. I've been prescribed a variety of antidepressants over the past few years, primarily because I am very sensitive to the side effect of 'nausea'. I just recently had a scope (upper and lower) which revealed I have chronic gastritis-undefined. Is this a result of antidepressant use? I'm currently taking 10 mg Trintellix. Will micro-dosing psilocybin help or harm? What dose of psilocybin would be a good starting place?
Also, you mentioned a 'Jamaican' trip. Where can I get information regarding that experience? I go to Jamaica frequently and would be interested in learning more!
Many thanks :)
Thanks, but I was hoping to find out about that 'JAMAICA' retreat mentioned in the video...
This video contradicts what i know about tripping under SSRIs . Everybody says that they cannot feel anything at all if taking SSRIs and psilocybin. Even if thay ingest 40++ grams.
So many studies confirm what I just wrote.
So where is the truth? I don’t understand. I listen carefully to the dr in the video and she seems so convincing and convinced.
Big big question mark ⁉️
I take snri's.lsd does nothing.psilocybine does
That is not at all true...I did a 7g guided dose and I take Zoloft and I had a full experience...so at least in my case, this was far from true.
@@storkbat thank you for sharing your experience ❤️ it gives me hope
I hope you can help. I want to
try psilocybin, but I take 15 mgs of Trintellix, and 7.5 mgs of Remeron ( Mirtazapine) a day. Not SSRIs. Can I do psilocybin?
Of course
This is Nice. Actually there is this reputable shroom farm, where i сор exactly same package, dude got (Gummies shrooms & chocolate bar) from two weeks ago. Still on it
On
Instagram
@TRIP_worlds2
👆 👆👆
That's the page name
From my personal experience as an autistic that’s tapering off Zyprexa and Trintellix it’s recommended to do 1 gram doses once a day while you taper off your medication.
You need a holistic psychiatrist.
What dose of psilocybin did they give participants in the study where they also used escitalopram?
do you know if you can microdose with escitalopram?
If anti depressants were very effective pharma companies would lose out. Best to keep people using. I remember when I was using them if I went to the doctors complaining of no improvement in mood, they would say double your dose of anti depressants. And I even went back again after the dose was doubled, and they offered more. They literally made me worse. Pharmaceutical companies can’t patent and sell a mushroom, they also only need to be used once or twice properly too, unless you micro dose.
All the talk about its okay to take psilocybin while on ssri, what about while on ssnri like cymbalta?
This was a very informative and easy to understand presentation, thank you for that.
I would find it interessting to know the risks and benefits of combining classic tryptamines (LSD, DMT, Psilocybin) with mood stabilizers. I'm taking valproate due to BPD.
There are many controversial meanings when having bipolar and taking psychedelics.
Can psilocybin macro or micro doses be administered and be effective while on a daily benzodiazepine?
@Dan thanks
What about Lithium? Are there problems using psilocybin?
I really want to know if I take wellbutrain for antidepressant will I feel mushrooms
I take Prozac mushroom did not work. Why?
One time when still in my teens I was able to use psilocybin. I am saddened that I never had an opportunity to use it again, nor did I have a prescribed opportunity. Where I live in North Carolina there is little hope that the doctors treating me will prescribe psilocybin for me. I have incredible difficulty stopping the use of cigarettes.
north carolina? bud they are growing constantly in the countryside , gotta go and look!
Thanks for this ❤
I've been talking desvenlafaxine for 3 years now im going to start tapering myself off. As i do so im going to take phylabcyben, so hopefully, i can get off it faster without going through the withdrawals.
what BS regarding SSRI´s.....its pure poison
Thoughts, anyone? I’m curious
Hi, thank you for the very informative video. It would be great if you covered a little more on SNRIs. I'm just a little confused by the notion that taking antidepressants can be healing, yet also after prolonged use it reduces receptors in the recieving neuron. That doesn't sound very healing :(
if you get your own genes tested, you can see if you have the HTR2A mutation that effects psychedelics, and interestingly...citalopram reduces it's expression even further, so if you have that g/g mutation, you probably need to consider if the antidepressant will surpress this seratonin receptor if you're also considering shrooms,. Not medical advice, but I think you're on to something
KBTV I wondered the same thing about the reduction in the receiving receptors, and it doesn't sound very healing to me, either. I would love to hear more about that. Like at what point of taking an SSRI does that happen (months? years?). And, after those are reduced, if you go off the SSRI will they regenerate?
Speaking on neurons and neuroplasticity, how does all this help someone with MS?
You talked about Psilocybin MACRODOSING being safe with antidepressants. But what about MICROdosing? It was not brought up. I would appreciate some input. I am trying to taper off Cymb@lt@ and am having a very hard time. Thank you!
You need to taper 10% a month to avoid withdrawals.
It may take couple years.
Are you switching to a new med? I'd bring it up to your psych. I am coming off cymbalta and going on Prozac. She gave me a schedule where I reduced cymb. And started Prozac. Haven't had any issues except a headache for a few days at beginning. Its different for everyone but slower the taper the less you will feel withdrawal.
I am also on that same medication, after doing research I found you have take half the dose of ur regular intake for a week or two
@@anatino not with cymb@lt@, its ez to wean off of that but you have to do it correctly
Got prescribed SSRI’s last week and this was the first question I had. Thank you for this video
Are you still able to trip?
@@EricCole69 yes
@@ZaoStrength Thanks for responding
@@EricCole69 not for me
@@zila626 I'm on 400mg abilify, once a month and I can trip from shrooms.
I loved this and learned so much. I’ve been on ssris for 4 years and this explains a lot. I’d love to have the slide deck for this. Thanks!
Can you take psilocybin mushrooms therapy while on zyprexa or olanzapine
thank you. this helped me alot.
Interesting information
Excellent thank you
Appreciate this. Been very curious/worried about microdosing while taking SSRIs. I've been nervous about SSRIs in general and have been sitting on a Lexipro prescription for a week. But this makes me feel far more comfortable and even hopeful that the two different methods may be supportive of each other in some ways. Though it does seem microdosing may not be effective [.15mg] when combined with the lexipro [5mg] so there may be some adjustments to be had there. I'm frankly not sure, beyond the first day, how much the microdosing has helped, though I've been very cautious with dosage and schedule so that may be part of it too. Regardless this is fascinating and hopeful! Thank you for your study and for sharing!
@aishahmohammed2623 Thanks but I'm all set in that department.
So how has your expreience been? I am on 10mg lexapro and I want to start microdosing. I'm in the early part of the video so I'm not sure what she says about SSRI's x microdosing. However, I gather from your post that you've starting dosing while on Laxpro. What have you experienced?
@@EdwardBose So I was microdosing before lexipro. I was afraid to start the medication so I wanted to give it a shot first. I'm on 5mg of lexipro. I've only been for a week and a half so far. I decided to wait until I adjusted before attempting to combine the 2. Sorry I don't have a practical response, but I do intend to give it a shot in a couple more weeks.
Im going to give it a shot in the next couple of days. I'll let you know. However, you were microdosing before lexapro- what did you find?
@@smoage
From my own personal experience with over 10 years of experience with trying to get off of various doses of celexa.
I had the brain zaps, the nausea, the dizziness, everything. It was absolutely horrible and debilitating a lot of the time. I finally found a doctor, who was willing to help me taper down very very slowly, and I started taking the supplement Sam E while I continue to gradually taper. I had to taper down over the course of a year in order for me to finally be able to do it with very minimal side effects. That was about 10 years ago and microdose thing is much more studied now, and much more of a known thing. I had had experiences with psychedelics, but never in terms of using them as an antidepressant. Although in retrospect, they definitely did help me get through some major issues in my life.
My main point here though, is that, if you have not yet started your prescription, I would wait. I would try microdose thing first and then if you’re still thinking, you really need the antidepressants then give them a try. I’m not a doctor, so I’m not going to say that this is medical advice or anything it’s just from my own personal experience I would strongly discourage anybody from ever starting to take anti-depressants of any kind ever unless all other options have been exhausted. They are a nasty medication. That very rarely actually helps people. In fact, the placebo groups in the studies they’ve done I’ve done just as well, if not better than the actual group taking the real medication
I’m loving this video and 3/4 of the way through it and on venlafaxine and I want to take my first mushroom experience. Does this video hopefully tell us how much a good milligram for first dose should be?
@Elian_ponce96 thanks I dont have those
In the study they use approx. 2 grams (a bit more). That’s quite a lot. I’d start with 1g
@@mirabrandt3351 I took 2 grams and it didn’t do anything much
Is there a more confidential channel to consult with you?
☝️☝️🍄
I am taking Wellbutrin (Buproprion) and I wonder what is the interaction between psilocybin and wellbutrin? Should I also take larger quantity of psilocybin because I am taking wellbutrin?
Just a heads up for everyone looking for medical advice here: I couldn’t verify Dr. Zelfand’s licensure on the Oregon Medical Board license look up. It appears she is not a licensed physician.
Erica if you read this - could you provide your license number?
Everyone is free to seek treatment in the manner of their choice and I support people seeking naturopathic or minimal-intervention therapies first.
However, if you are a neuroscientist or fellow medical professional looking for well-informed advice on the neurochemical interactions between SSRI’s and the agonist effect of psilocybin, seek it elsewhere.
In the beginning of the slides it says she is licensed as a naturopathic doctor. They don't emphasized in the video that she is not an MD or DO. The distinction is important. Also doesn't mean this information is useless though.
I was really hoping combining psilocybin and Trazodone (SARI) would’ve been discussed. It’s not an MAOI, but also not technically an SSRI. Can I take psilocybin if I stay on my current dose of 50mg of Trazodone per night (for insomnia)?