DOCTOR reacts to CELLS AT WORK! // Episode 8 // "Blood Circulation"
ฝัง
- เผยแพร่เมื่อ 28 ก.ย. 2024
- Back by popular demand! I breakdown the scenes from the Blood Circulation (episode 8) of the fantastic Cells at Work (Hataraku Saibou) from a real doctor's perspective. I'll be reacting to scenes and explaining a little bit more about what's happening in the show and sharing some of my experiences as a doctor.
In this episode we cover; blood circulation (obvs), valves, what is a heart murmur, the portal system and a few other bits.
As with all these reviews I skim over a lot of medical terms, please leave a comment if you want any clarifications!
This is part of a series reviewing Cells at Work, you can find the whole playlist here:
• Doctor reacts to Cells...
You can watch Cells at Work! here:
crunchyroll.com...
This episode didn't have as much immunology as the last one, much more physiology but I tried to add in some insights where I could, so if you enjoyed this please check out my other reviews of Medical TV dramas; House MD, Scrubs, The Good Doctor, Grey’s Anatomy, The Resident and ER! And also I did a series on Marvel movies too, more on that soon.
Instagram: / drhopesicknotes
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Clips used under fair use (education and review):
THANK YOU FOR NOT COPY STRIKING THIS VIDEO SO I CAN CONTINUE TO USE THESE GREAT SHOWS FOR EDUCATION AND REVIEW.
ALL Cells At Work! Clips owned by Kodansha / Kodansha USA and distributor Sony Music Entertainment (Japan) Inc.
Thank you to all the artists that make their music available for these videos:
Song 'Escapists' by The AutoDisko
Song 'First Day' by Huma-Huma
Song ‘Finding Me’ by Eveningland
#doctorreacts #doctorwatches #cellsatwork
Thank you for your patience everyone; I promised this video last week but only just got around to completing the edit... I was pleasantly surprised how Cells at Work handled general physiology rather than immunology, so looking forward to seeing what happens next! Hope everyone is having a super week! X
Dr Hope's Sick Notes I just recently started watching your channel and wow i love your videos. However, i still wonder how you have time to do TH-cam. How do you have the time???
@@nipahnoob he records in batches when he got free time which is rarely
I like your explanation for CAW!!!! Thank you!! Hope to see more!
About the statues... they are just Onis. An Oni is a kind of demon, or ogre, of the japanese mythology, or they may be Kamis(gods). It's just a cultural reference, because the heart looks like a traditional japanese temple for the cells. I hope that you can understand what I meant to say, because I'm brazillian, and I had to learn english by myself, so, I still have some difficulties with the language... specially in terms of writing.
for the statues they are the Nio, are a pair of protectors who commonly stand guard outside the temple gate at Japanese Buddhist temples, one on either side of the entrance. The right statue is called Misshaku Kongōand has his mouth open, representing the vocalization of the first grapheme of Sanskrit Devanāgarī (अ) which is pronounced "a". The left statue is called Naraen Kongō and has his mouth closed, representing the vocalization of the last grapheme of Devanāgarī (ह [ɦ]) which is pronounced "ɦūṃ" (हूँ). These two characters together (a-hūṃ or a-un symbolize the birth and death of all things. So they represent in lay terms the deoxygenated blood cell are "dying" then they are "reborn" or become oxygenated blood cells
The gargoyle-like statues are likely a reference to Kaminarimon Gate in Asakusa, which leads to Sensoji temple. The gate is flanked by statues of the thunder and wind gods. It fits with the temple like depiction of the heart. Though I suppose the thunder god could reference the electrical impulses of the heart, and the wind god could reference the breath oxygenating the blood.
Oh wow thanks for the info.
Yeah definitely the same ones in Asakusa. They are also supposed to be guardians that separate what is impure from what is holy so it makes sense thematically that they stand between clean and impure blood.
Many Japanese temples and shrines have these, though, so probably a more general reference than that.
They are called Raijin and Fuujin, and they are very common guardian deities found at the gates of many temples in Japan.
I was going to make a similar comment but you summed it up better than I could have. I'll just add that the 'cramped passageway' that the Red Blood Cells go through on their de-oxygenated journey into the heart are called Torii Gates, and they are found outside of temples and shrines. Supposedly they form a sort of 'spiritual corridor' for people on a spiritual journey to said temple/shrine.
Dunno why they chose to represent going through the heart as going through a shrine. It's . . . odd to say the least. I do like your idea that it has to deal with wind/Oxygen and Thunder/Electrical impulses.
Wait, did red blood cell _finally_ , legit, for once, navigate her way though the blood circulation system without losing her way?
*Coagulations* !
Jeremy Chan please see yourself out
Do NOT see yourself out!!
Platlet-chan: *someone called?* 😶
You will (not) circulate around the body.
@@laurenceraran4027 She (N)ierly did.
*I legit turned pale when I heard "Krebs' Cycle"*
The damn thing was the bane of all people studying for the metabolism exam, and I swear I had nightmares after that.
Luckily, we all remembered that in the end of the day, *mitochondria is the powerhouse of the cell.*
Yeh I should have given a trigger warning ⚠️
i hate biochem.. all those cycles..nightmares..
Krebs is the german word for cancer ... so i guess have fun with that ;D
I had a nightmare after I learnt Kreb's Cycle. It was a struggle to remember all the reactions...😔
And of course, I have since forgotten basically all of the Krebs Cycle, in spite of memorizing every damn bit of it. Really makes all that suffering worth it doesnt it!
"... a process called the Krebs cycle ..."
**shivers down my spine from the PTSD**
I thought I was the only one. Is anyone here hosting a support group?
It makes more sense now why you crave sugars to get fast energy...this episode really broke down everyday things
It is amazing, the krebs cycle. Very easy if you associate it with something like a story
Satish Yadav isn’t Glycolysis the Linked Reaction and the Krebs Cycle easy processes to remember?
@@ley5532 that's what i said, they are easy but we need to concentrate and associate.
Oh my God Ed, when you said "you must say, it's the powerhouse of the cell", I lost it. I'm a biology teacher, and I feel like that's our motto
_Anime characters being anime characters_
Dr Hope: This is exactly what happens in our body
Heard here first folks anime is real
I guess this is what happens when you have anime in your veins.
We bleed best girl
Well, looks like Undyne will be happy to hear it!
The real anime was inside us all along!
@@eskreskao Uryu Ryuunosuke coulda told ya that. Kiritsugu showed it to him with a bullet.
I've watched this anime twice and I never even noticed the jacket color detail! What a nice touch!!
Aniplex announced that they are releasing Cells at Work dubbed.
Same here
Never noticed it in the anime myself, but the manga outright states that it happens.
their hats inflate and deflate too
This situation was also shown in the manga on one page, explaining how their jackets work-although i forgot what chapter that came from lol
I was talking about you with my friends and I was talking so fast I accidentally merged 'anime' with 'medication' and ended up saying: 'animedication' and we all laughed about it
Well it should be a term :D that's how I overcome my anxiety 2 years ago :D
@@mehmetgurdal Thats how I overcome my first big depression crisis 12 years ago.
*He got anime and medication on his side!*
Edit: My highest liked comment ever. Thanks.
Mystic art of animedication.
Animedication no jutsu
@@GregAtlas lol that made me laugh😂
nice vine usage xD
@@LoreCatan That's how we swing. **Tarzan yell**
The man, The Myth THE DOCTOR is back at with the cells at work review!
I was expecting you to say 'The Legend' but 'The Doctor' is good too
Yeahh!
Scoot sterling...
@@cye2310 I'd go with "The Medic", but that's because I'm very fond of alliteration.
"THE DOCTOR"
*_Dr. Who theme song plays_*
"Still doesn't stop them claiming my videos though :)"
You've made my day, Ed😄
“The only artery that carries deoxygenated blood”
Haha. Boy are med students happy every single time that questions pops up in the exams 😂
This is a stretch, but this isn't strictly true. In fetuses, their arteries carry deoxygenated blood.
I am sorry I have alevel bio exam in a few days and I cramming. Thought this was a good way to active learn. Apologies for being nit picky
Wow . They r so correct when they say biology is at its best when u can actually imagine whats going on n how it works n why. Never occurred that yea , featus also carries oxy n deoxy blood .
The day that I realized arteries carried blood away from the heart not oxygenated blood blew my mind
The statues look like Raijin and Fuujin, gods of Lightning and Wind. Lightining = electrical impulses, wind = gas transfer.
They are because the area is modeled after the Kaminarimon (literally Thunder Gate), the outer gate of the Sensou-ji in Asakura. The gate is adorned with statues of Fuujin and Raijin, who spiritually separate what is impure from what is holy. In this imagery, they are separating the blood cells between dropping off and picking up.
This proves that they are living in a Japanese weeaboo
To be honest, I thought the thunder deity represented the heart beat, cause when your heart beats, that means it's doing it's job right and blood is flowing properly throughout the body.
Plus the guy is known for his drums, so I thought that was the connection.
A deity to represent the air in the lungs and a deity to represent the beating of the heart.
I just thought it was a red and a blue ogre, representing the artery and the vene. Maybe both?
@@goldenlion886 This comment was too funny to pass but to inform you, Japanese weeaboo doesn't exist cause wee-a-boo is a term referring strictly to foreigners who are so into Japanese stuff and wants to be a Japanese to live on their fantasy about Japan, disregarding the other truths about the said country.
Also this show and the original story were made by Japanese people. I think it's normal to want to put part of your nationality in your work.
Your commentary is uncontestably wholly transformative; don't let the copy claims get you down!
"Cool... so the Red Blood Cell is... lost again."
I'm laughing so hard.
by the time he finishes this season, the next season will be already out
Let's Hope. (ba DUM tss)
Oh, how I wish that were true :')
It's not out yet
It’s confirmed to be released in January 2021.
Oh my goodness! I've been Hopeful that you'd continue.
Thank you so much, Doc Hope
Me to! It is my favorite series!
Sameee!
was that an intended pun? XD
@@jq3267 Yes
There's a pun right there
6:17
It's so wholesome how he's bobbing his head to the music. 😭
I'm sorry if this has already been pointed out somewhere.
It is said in the video that the mitral valve was not described in the video, but I think the two gargoyles pointed out in the video are the description of the mitral valve.
By the way, those gargoyles are properly called Niou statues. They are there to protect the temple from the bad guys.
The mitral valve is known as the "僧帽弁" in Japan.
The Chinese character for "僧" in 僧帽弁 to a monk in a temple.
I think that scene probably depicts the mitral valve in the form of a Niou statue, hooked to the kanji that refers to monks in temples.
... It might be hard to convey this feeling unless you're Japanese or have lived in Japan before.
Being Japanese, I didn't understand English, so I relied on translation sites for everything.
I'm sorry if there are any oddities. I apologize for the long text.
My life is a mess but feeling smart from learning new terms makes me happy, thanks for letting us watch that show for free.
There's a part where she and her other blood cells are walking through the inferior vena cava and above them is a large dark blue pipe. Very clever seeing as how veins are blue on the outside of the body, they made the pipes above the veins blue. It just goes to show you how much thought and detail they put into this anime.
I'm in EMT school and my class had a brief glimpse at the circulatory system. Watching this episode after that lesson was like a complete nerd-out moment for me! I was able to point out the major parts of the heart and trace out the path of the oxygen-depleted blood, oxygen-rich blood, and so on!
My dad is a consultant at a training hospital in my city and also the dean of our university medical school. I showed him some clips of this anime because I really love it and he found it cute. He also seems to approve some of the medical info they share. So if it's good enough for him, it's good enough for me to continue watching.
I really miss the series. Thank you for continuing them! Much love
There's gonna be a season 2!
@@lets_talkabout_anime That's great! Would love to know more about the cells/characters, since I rarely read any mangas/ln nowadays. Thanks for the info!
Chitaka06 Wait really?? When?
After watching these videos from episode 1 to now it absolutely blows my mind how our bodies are designed for so many different jobs, its incredible.
i presonally loved the detail of using a temple bell for the heartbeat itself, rather than reverberating the whole room
Not even one minute in, and Dr. Hope already blew my mind. When I watched the episode back when it released I didn’t even notice they switched the Jacket’s color depending on it’s oxygenation!
Yaaaaay! A new one! It’s been a long time. ❤️
Way too long! But at last it is here 👍
Finally! 😂 Who else has been waiting for this? 😂
Me!!!!!
@rihardo123 me too 😂😂 been waiting for ages 😂
Your profile pic describes my elation!
@@UGNAvalon 😂
I honestly can't wait for the review of the last 2 episodes.
Doc Hope never fail as a hope, we have been granted a new episode of cells at work reactions/breakdowns.
Grab your notes everyone!
Somebody already mentioned this, you should review John wicks injuries. Love your Cells at Work series btw.
"Headshot, headshot, headshot, pencil through eye..."
@@quietwyatt2873 recently killed a man with a book. Handing out KNOWLEDGE
That would be AWESOME.
FIRST! This episode is one of my favorites!
What I loved about this episode was how much White Blood Cell cared for Red. I was half expecting you to talk about some memories of doing rounds all on your own. The next episode will be interesting, giving insight on why Killer T cell needs to watch his salt intake.
I know! I was hoping to see him talk about the white blood cell caring for the red one. It was so sweet!
Wait that collar switch on her jacket thats such a cool attention to detail im amazed you noticed that!
To be fair, it's been mentioned countless times in the comments of past videos and for what it's worth it's explicitly mentioned in a bonus page in the source manga.
I must say, watching this again is making me feel really conscious of how I overwork my heart and cute little blood cells. Having a doctor explain the human body using an anime of the subject is a dream come true.
ive watched the anime and also read the manga and thought that those 2 statues were actually the bicuspid valves ahaha
It's both an education and a story as in this episode Red puts the effort to get her job done all on her own so you can't help but cheer her on
It's been a long time coming! Btw, a second season had been announced for this series! Thank you so much for all your detailed explanations! It's still a long way, but there was like an extra episode (Episode 13, essentially) after Episode 12, talking about colds and I was very confused by that episode so looking forward to hearing your explanations on the upcoming episodes!! Thank you so much!
When and where was it announced?
It keeps amazing me how mechanical bodies are, with the pumps, valves, electrical signals, etc., yet so intricate we're nowhere near fully replicating it.
OMG! I clicked as soon as I saw it. I've been wondering if you would continue to do these. I am so happy.
Oh my god I didn't realise that you'd resumed this series!!!!! What an absolutely lovely surprise, thank you doctor!
If I had to take a quiz after watching an episode of Cells at Work, I'd ace it. What an incredibly genius way to teach! And I learn even more from Dr. Hope. 🙏🏻💕
Cells at work, my favorite series!
Upon watching the episode, I just loved how the heart was this crowded temple, as in many festivities, the temples do get incredibly crowded (and the overview shots just help us realize their berets are shaped like blood cells xD) and I actualy measured the sound of the drums to my own heartbeat, and in some scenes, the drum actualy matched my rate (which was at normal speed, I can assure you).
Thank you, Dr. Hope :D I reaaaaally have been waiting for this video - not only because I'm learning to understand English watching your content but also it brightens my day hearing your calming voice and looking at this funny entertainment. Keep up the good work but take your time. It's a lot of work producing these clips.
I'm looking forward for your next video, greetings from Germany/Bavaria/UpperPalatinate
I love how your videos are always well explained. It shows that you're not reacting at it just for views (because of its popularity), but rather because you find it good and want to share interesting points with us (that only you could explain so well!!)👍 You've got a new subscriber~
I love your reactions, and i like learning all these things, especially from you doc, its a win win, continue to make great videos ❤!
"the kidney maintains ph lvl on the body by getting rid of the waste"
A simplified version of pissing
About the heart and the statues, the heart itself is based on japanese shrines and temples (in Japan the two are slightly different, one word means budist and the other Shinto, a traditional japanese religion, but dont remember wich one).
Japaneses are not really religious, but they have a strong tradition of going to a shrine / temple in January 1st and it always got HUGE amounts of people (imagine an entire city going to the same church at the same time, its crazy). That "somewhere where everyone goes in regular basis" and the drums / bells (representing heartbeats) makes that symbology really good, but hard to understand to non-japanese people.
The two statues (and the big bell, and the Toriis in the scene where they're waiting in line) are traditional symbology of a shinto shrine/temple. That's not a medicine thing (except the bell and the drums, they are both religious symbolism and heartbeats).
Cool thanks!
Dr. Hope: "A process called the Krebs cycle."
Any medical student or doctor watching: *1000 mile stare into the distance*
I actually am a heart parent who had a heart murmur which turned out to be my mitral valve never closing properly, never knew the actual word for the specific condition though!
Patient do you mean?
@@alucozadebottle4423 no they have a heart child /j
1:05 I NEVER noticed that her clothes changed! I guess I don't think I ever would have if you hadn't pointed this interesting little tidbit out. Man, this series was so much more researched than I ever imagined.
Welcome back! Yeah I agree that by congestion I think they mean heavy traffic. Not much to add on the circulation episode, it's all quite chill, which is probably needed after the last one.
The first pathogen you show, I suspect to be Shigella for a few reasons:
1) Rod-shaped and spiky, though that can also describe any of the Bacilli.
2) Pink face, suggesting gram negative. This rules out the Bacilli.
3) Haemolytic action as first attack. This narrows it down to species which are notably haemolytic, so we run the gram neg rod list:
3.1) Salmonella ferments for energy and mostly takes free nutrients, so no.
3.2) Vibrio (cholera) isn't noted for it, and we've already seen it in show.
3.3) Pseudomonas is haemolytic, but has already been seen in-show as the one-eyed bogie, so no.
3.4) Serratia tends more towards tissue destruction. Still on the table as it's an opportunist and our patient is a week post-cancer, but no. Most common in HIV patients, and our T cells and macrophages seem in full vigour!
3.5) Escherichia depends on strain and is a good candidate, but seems the kind of bug that they'd save for an episode. Maybe a special like the common cold. Escherichia is my second choice for this.
3.6) Klebsiella does look like this, with that thick white sugar capsule, but it's another fermenter which munches on the free glucose. I don't remember (though it's been a long time, I may be wrong) that KP has any notable haemolytic attacks, so no.
4) Having said all that, we seem to be going for a very Japanese flavour with this episode. The temple, the statues, et al. Shigella ticks all the boxes, is strongly haemolytic, and was discovered over a century ago in Japan by a famous Japanese doctor, Kiyoshi Shiga.
I submit to you that the spiky bacterium is *Shigella sonnei* in particular. Thankfully Neutrophil got in there quick before the patient started peeing blood.
I love how the heart is portrayed like a temple with a huge bell keeping time. It's a great visual metaphor.
Not sure if anyone's mentioned that the heart is depicted as a Buddhist temple, with a Japanese style walkway where festivals are held (and yes, they can get rather crowded); so the two statues are Nio, which kind of accentuate the aesthetic. They are kind of wrathful guardian guards and manifestations of the Bodhisattva Vajrapāṇi. They are also an interesting case of Greco-Buddhist influence on East Asian Buddhist art. In Alexandria Eschate, an ancient Greek city in modern day Tajikistan, there's an old carving of Vajrapāṇi appearing as Heracles, defending the Buddha. As the art moved east along the silk road, it ultimately became that
I'm japanese.
The Gargoyle is 「阿吽像（AUN-zou）」.
This mean is 「阿（A）＝born」「吽（UN）＝death」、set mean is 「the Life」.
Because, in Heart scene is very near likeness,「浅草（Asakusa）」at「New Year's Eve pilgrimage（大晦日oomisoka）」.
Bell, gate（鳥居tri-）, and congestion,very near！
It is always good to see you again no matter how long the wait. Awesome video as always.
1:07
I never noticed the color change before! Good catch doc!
I love how you're so hyped when the anime makes clever analogies
This episode has story, but it's subtle. The red blood cell we follow has always had directional issues. But here, she overcomes them and find pride in making a delivery without getting lost for the first time.
Glad you are picking this series back up! But sad to see that they have been claiming your videos. This must take more time editing since leaving any clip up too long could trigger TH-cams' algorithm. Seeing your insight into the show and what you add with knowledge and wit really should be considered as transformative. Thank you for doing what you do, I really appreciate it, and by the looks of it so do many others.
Awww thanks. Comments like this make it all worth it!
You are very helpful, I had a "systems of the body" pop quiz and I remembered this. Thank you😇
If I ever see you in real life, It would be weird to look into your eyes without seeing the RingLight Reflection
Lol ikr. His pupils are almost never visible lol, just his irises
I've been waiting for this 😄✨
Man, whenever I see a heart diagram I always confused if the right side is my right or my left since it's mirrored
In medicine it’s always as if the person was facing you.
1:08 Y'know I didn't notice that until you pointed it out, that's some neat details they added in
Hey doc!! I saw the notification and just... stopped everything I was doing. Really enjoy this series!! I was starting to miss it.
I see a hope cells at work reaction,I get to the video as quickly as possible!
This and a English Dub announced this has been a great week for cells at work content for me
i never noticed the diference in color of the clothes of the red blood cell!! that's such a detail!
Holy heck I never noticed she switched her jacket to a darker color!! I've watched this series 3 times now but every time I really do learn something new.
I have been waiting for this reaction for a long time
It took you long enough DOCTOR, happy to have you back
There sure are lots of people like me, waiting for Dr's continuation of this series :3
How many times has Dr. Hope said the Red Blood Cell got lost again? He's just bring a new enjoyment about it. Awesome!
Literally me when I saw the thumbnail:
*GASP* FINALLY YEY
I was like "ok, 5 in the morning, time to go to be- OMG NEW EPISODE!"
At one point, Red Blood Cell notices that when in the Inferior Vena Cava, it's hard because it's all uphill. The blood in the Inferior Vena Cava comes, as you said, from the lower abdomen and goes to the heart, so it's moving against gravity.
Doc, I really hope you get a cameo in the English Dub of the show XD
The dub will be released on blu ray on aug 27th
Thank you sir, someone on this discord server showed me these videos and i've been addicted sense. Thank you for showing this. It always feels good to learn new things, especially the parts of medical terms.
I F O U N D Y O U
I didn't realize it until I saw the scene again: in the pulmonary scene showing the alveoli, there's a monocyte cleaning the window; an alveolar macrophage!
Cells at Work is getting dubbed in English
Now there's no reason not to use it in schools with a dub.
0 Zerocopy if there’s no reason a teacher can just make 1 up not sure why one do this tho
I'm a Biology student and this episode really helped me remember how blood circulation happens in the body
You’re so interesting to watch, I don’t know what it is but when I watch you and learn as you talk it’s just so nice
DO MORE OF THIS WE NEED THIS.
If Red Blood Cell ever falls victim to hemolysis, I will cry.
Hi! I live in Japan and just found this series (I love it!!!) And I have been studying Buddhism/Shinto and my husband actually graduated from the biggest Buddhist colleges in Japan for the study of Japanese and studying religion. Many of the references are direct references to Japanese tradition and beliefs. Such as the big bell and statues. The statues are known to protect temples most commonly called Nio. If it were to have been more Shrine like, you would have seen あ(ah) or ん(n) which are dog like dragon guardians outside of shrines. They get their name because one has an open mouth (あ) and one had a closed mouth (ん) so they were named after the sound they believe they make. :)
Some Japanese people believe your heart is a theoretical temple or shrine in your body 😊 so the entire heart is made to look like a temple/shrine in this show. Japan loves to put its own tradition in things, or even just things that they know are very "Japanese".
This can be seen more casually in the vending machines. Anyone who has been to Japan knows there are vending machines EVERYWHERE 😂 so it's a little touch on where the anime is made. Another example is even in the way they deliver the oxygen; in my small town (Ishikawa-machi) we have post men who carry the boxes on those little trollies, if they're not on bike. 😁
YESSSS I've been waiting for this!
The most important fact in this episode: The T in Killer T stands for Tsundere
I was worried this series had become benign after the cancer episode. But, I'm glad to see it's malignant. Poor word choice aside, good to see you're here and here to stay!
10:05 I'm surprised you didn't mention anything about the guy spreading surfactant on the alvioli. That's an amazing little touch of a detail that they did not have to add.
thanks godss!! thank you, doctor. i have been waiting for long time.
I can't believe I never caught the subtle change in her jacket color!
actually that was openly written in the manga volume 3 (i think so?)
Oh shoot, the return of Cells at Work!
You know when a science teacher said we need an assignment about circulatory system, this is the assignment I will give
finally!! the docs back!!
fun fact, I have a bicuspid aorta valve, (two flaps instead of three like normal) which results in valve insufficiency and a heart murmur (though it is not a huge problem, my heart still pumps blood fairly well, and as I understand it is one of the more common heart defects among people who have heart defects)
Every time I hear someone mention "Mitochondria", I get Parasite Eve flashbacks...
Great game.
Same, love that Game
Learning something new everyday.
Those statue is a reference to Japanese culture thay are protecters of holy sites
It's fun watching your reaction videos after I watch every episode. I at least get to hear a legit doctor with the things I've watched in the anime.