I was diagnosed with MS years ago, later diagnosis changed to Neuro Behcets. Modafinil has helped with cognition and fatigue, without the jittery feeling.
Great story... Eeriely similar to me… I'm 41, decided to go back to do my masters at Sheffield Hallam..ive been out of education since 2004.. First two weeks I had a slight panic at the pace and level of info.. Trying modafanil as I had read all the doom and negative stories… As you say it puts you in your best possible state of mental clarity and mood, like a day where you've had the best sleep, breakfast, life is good and you're fitbsnd healthy then you have a cup of tea and get the mental uplift for a day. There are downsides, sometimes it doesn't work as well as previous times, and later in in the evening you don't get a desire to go to bed, but it doesn't inhibit your sleep
Well said Dom. Modafinil is a game changer with cognitive function/concentration for me. I do limit to a ‘take only when really need to’ basis, but it’s great stuff. And yes, as we’ve discussed, impossible to get prescriptions! Neuros seem to dismiss fatigue from conversation and work based solely on physical ability. Very frustrating
I was prescribed Modafinil for sleep disorder, but didn't help at all, it was like taking a sugar pill placebo. It may work for some, but it's definitely not the wonder drug it's made out to be, everyone's biochemistry is different. Turned out that sleeping about 6 hours wasn't enough, now I speed 8 hours and everything is fine. :)
I've been using Modafinil for a couple of years; it really is a game changer. I felt physically and mentally better from using it. Didn't have too difficult a time getting it from my GP once it was recommended by my MS nurse. Unfortunately, I have SPMS so my fatigue has worsened, currently taking 2 a day. My MS carers don't like me drinking coffee or tea.
Thanks for the informative vid Dom. Modafinil changed my life post-diagnosis. I'll tell anyone who wants to know and I'll share this video if they want to know more 😉
When I had money, I was easily prescribed Modafinil for ADHD, as any other drug (scheduled) affected me adversely. I was forced to go on disability and instantly my new doctors refused to even discuss putting me on it, because even the generic is still more than Medicaid will pay. So, now I start projects all over my home, never finishing them. I sit and cry and feel worthless. This is no way to live. Even my volunteer work has stopped, as my racing thoughts don't slow down long enough for me to organize makeup, clothing, etc. Being on disability is tough enough without what little life I had being ripped away. It's really a terrible situation. I had been on a very low dosage for twelve years, so I certainly did not fit the profile of a drug seeker!
I was just prescribed Modafinil. It is absoLUTELY a game changer for me. MS fatigue and foggy brain have been greatly reduced for me. Thanks for the tips! 'Good ideas on how to get the most of one's daily dose. Best wishes to you, fellow MS warrior. (That's how I feel about all of us who face day-to-day challenges brought on by MS.)
Great video I hope this helps people with MS. My Dr. (you know him well) always asks how I am doing, what things are difficult. I told him I no longer multitask well. I don't necessarily have cog fog but I do get distracted extremely easily. I can't listen to music while I work and my surrounding must be absolutely quiet. He said let's experiment and I tried a Provigil. I loved it! I could access my memory and my multitasking improved regardless of my surroundings. Felt like Bradly Cooper in Limitless. I am a bit funny about prescriptions I take them as little as possible. I kind of think the less I take them the more effect they will have when I do. Great video thank you for sharing
Modafinil is easily obtained in the U.K , goes under 2 Indian pharma labs , quid a pill , a lot of TRT users get it from the same source , great pre-workout when done with caffeine
I’m this guy you refer to. In the UK there are v tough rx guidelines for male TRT therapy. Are you advocating a gel, an injection or tablets? I am not anti I just know little about it. Do you get it privately?
@@theMSguide Nah im in the US, ive seen other youtubers post from Europe there ability to gain access to it through TRT clinics. Always intermuscular, you'll Cypionate from cottonseed oil. They will start you low then build you up in does. Try to get to 200 mg per week at the beginning. Ive been on it for 1.5 years and now self administer about 280 mg a week split in 2 doses
@@theMSguideFadgio Agrestis - 600 mg Zinc - 50 mg TongKat Ali. - 400 mg Take everyday first thing in the morning 5 Days on 2 Days off Get your testosterone checked before you start Check it again 90 days later I guarantee your testosterone will go up And your testicles will get bigger So if you feel some slight discomfort in them Don’t worry Just means it is working Anthony Huberman has videos on this here on TH-cam. It works well Also when you get blood work done Check total testosterone and free testosterone and also LH
I have very debilitating fatigue from brain cancer and think of asking for this. I still need to function at work and it’s nearly impossible the way things are.
Unless the doctor can tell you why it places you in imminent danger - not a tiny theoretical risk from a small trial - then ask them to record that you asked to try it, they denied it and the medical reason behind that denial.
Get it prescribed in the UK. The NICE guidance for treating MS lists Modafinil as an approved pharmacological intervention for fatigue. The guidance is NG220.
Really appreciate the tip. My job requires a lot of mental acuity and often detailed analysis of large, dense text. These days, I open up a document and my heart sinks.
I was doing an MSc when a neuro recommended it. Utterly transformational. There are the yays and nays. Denial of t is puritanical nonsense. Now NICE mention it then any neuro who says no needs to be be sacked off. Drop me a line at dominic@theMSguide.com for more specific tips.
Dear Dom, thank you for this video. How did you know that Modafinil could help you? Did you have to do some tests at the clinic for example? I cannot buy this in Bosnia as it is not registered, however, if it is such a game changer as you say, I will ask my family members who live abroad if they can purchase it...
I didn’t know. A neurologist prescribed it without me asking for it. I know the students at university buy it from online pharmacies. Singapore I think.
I'm not a medic. I Googled 'drug interactions ssri and modafinil' Try it out (the Googling) but when it all matters is speaking to whomever prescribed the ssri (of which there are many variations)bis the most important.
Yes. I am prescribed 400mg Modafinil and escitalopram. I recommend getting it through the do ctor instead of online. It's easy to get and generic is cheap.
@PwncakeOW In my experience (USA), it's not so easy through a doctor. It can be done, and I have a script, but there are serious hurdles in the way. If I were doing it over, I would definitely just skip the doctor, hands down. Online it's relatively easy, but it's good to be discerning about the quality and reliability of the source.
I have sleep apnea , I take 4 naps a day. Im concerned about driving long distance so I talked to my doctor yesterday about modafinil. She was very nasty to me. She treated me like a drug addict asking for drugs. She said nobody has EVER asked me for that. I am NOT going to prescribe you a CONTROLLED substance.
If you are in the UK it is most definitely not a controlled substance. It is prescriptible on an FP10. Ask any pharmacist. It says more about your doctor than you. They can start with 28 days of 100mg. She is just being obstructive. If you have MS then it is on the list of NICE approved Meds for MS fatigue.
I am among those for whom it does not work at all - only negative side effects, the worst of which begin in the afternoon, after taking it in the morning. I don't sleep well the night after taking it, and still feel crappy the next morning. Even during the morning hours after taking it, there's nothing positive about it. Just negative side effects, but not as negative as later in the day. Caffeine plus L-theanine and L-citrulline are far better in my experience. So is guayusa tea. So is yerba mate. So are some of the pre-workouts (like Nutricost's).
brov coffee + modafinil you are frying your brain. I take 35mg as soon as i wake up, fasted. Thats the best way for me and ive tried every dose combined with coffee.
@@theMSguide Hey! sorry for typo, i did not mean to type "brov", just coffee :) I am 28 years old and my brain is younger than yours. Maybe this has to do something with it. I have been experimenting with modafinil for the past 4 years and I do love it. For some time, my ideal dose was 1 cup of coffee with 50 mg of modafinil. However, it became difficult to balance that with proper sleep , and I felt sometimes I would be very productive on the day I took it at the expense on the next day productivity / brain power. I have found that less is more when it comes to Modafinil. Especially if you already mix it with caffeine. Taking it as soon as I wake up helps tremendously to have good night rest. I read somewhere that half-life of Modafinil is around 12 hours. It will stay in your system and wont let your brain rest at night. Thats my advice from personal experience :) Nowadays, I only use it once a week, sometimes less. However, I might go on a modafinil cycle for higher productivity and focus on the remaining months of 2023.
I take 400 mg to stay up for 24-28 hours in a go, then 2.5/3 hours of sleep, then all over again. Yes i found tea / coffee + modafinil a best combination. Although I do take short nap of 10-20 mins before taking another dose of modafinil ( when power of 1st wears off) around once in every 8/10 hours. And that short nap makes me feel energetic again. At last, it's not only about modafinil, it's about will power, modafinil it's just a wakening agent, but to plan it, and willing to take it. Ultimately body recovers, pain also relives, but the only thing which we carry forever is our achievements and legacy.
@@theMSguide No? That is interesting, is it a 200mg slow release pill you are using? And what brand name is it? I take 100mg Pils. From modiodal® They are a bit like oval shaped tablets. but they have a very weird sweet chemical taste!! And when it has gone through my system after about 4 hours i can smell It in my pee! 🤷🏻♂️😅 I have a fast metabolism so I need to take it again after 4 hours. But maybe it's one of those smell's only people who can smell asparagus in there pee, can smell it?! 🤔🤷🏻♂️🤓
@TheOpticalFreak there is a half life for the Modafinil molecule so your rate of metabolic processing can’t change that. In the UK a brand isn’t used as it is long out of patent protection. I know the most popular branded pull (exactly the same molecule) is ProVigil. There is no SR preparation on the market here. I make a point of taking it on a full stomach which slows the release into the system. It is my prop. It isn’t always perfect but I can sure tell if it don’t take it. If your urine has an odour it could well be from all the inert binding and glazing agents in the pill and quite likely not the molecule. Does the Patient Information Leaflet make any reference to this?
@@theMSguide i need to check the leaflet instructions, but I also had modiodal, modafinil, from a different brand/producer 100mg pills and it tasted the same. And I could also smell It in my urine after 4 hours! 🤷🏻♂️ so I really believe it is the molecule it self. But there is this thing that some people can't taste a certain bitter compound or smell asparagus in there urine! It has to do with your DNA wish I find really fascinating! 😃
for many years i suffered from unknown tired and how to explain like very tired Need Lots of Rest after Rest you Feel Rest again Until my Doctor prescribe Modafinil.All my time spend for tiredness and rest Gone Hopefully no Side effects on Me.i really can do what i plan for my life from home working to outdoor works
I was diagnosed with MS years ago, later diagnosis changed to Neuro Behcets. Modafinil has helped with cognition and fatigue, without the jittery feeling.
Great story... Eeriely similar to me…
I'm 41, decided to go back to do my masters at Sheffield Hallam..ive been out of education since 2004.. First two weeks I had a slight panic at the pace and level of info.. Trying modafanil as I had read all the doom and negative stories…
As you say it puts you in your best possible state of mental clarity and mood, like a day where you've had the best sleep, breakfast, life is good and you're fitbsnd healthy then you have a cup of tea and get the mental uplift for a day.
There are downsides, sometimes it doesn't work as well as previous times, and later in in the evening you don't get a desire to go to bed, but it doesn't inhibit your sleep
I like your description.
Well said Dom. Modafinil is a game changer with cognitive function/concentration for me. I do limit to a ‘take only when really need to’ basis, but it’s great stuff. And yes, as we’ve discussed, impossible to get prescriptions! Neuros seem to dismiss fatigue from conversation and work based solely on physical ability. Very frustrating
I was prescribed Modafinil for sleep disorder, but didn't help at all, it was like taking a sugar pill placebo. It may work for some, but it's definitely not the wonder drug it's made out to be, everyone's biochemistry is different. Turned out that sleeping about 6 hours wasn't enough, now I speed 8 hours and everything is fine. :)
@@BillAnt Do you use any over-the-counter supplements/vitamins?
Me? Certainly.
@@salesmindestandbusiness1678 - No med, other than an A-Z one a day vitamin, and lately Kratom powder which helps with sleep a lot.
I've been using Modafinil for a couple of years; it really is a game changer. I felt physically and mentally better from using it. Didn't have too difficult a time getting it from my GP once it was recommended by my MS nurse. Unfortunately, I have SPMS so my fatigue has worsened, currently taking 2 a day. My MS carers don't like me drinking coffee or tea.
Thanks for the informative vid Dom. Modafinil changed my life post-diagnosis. I'll tell anyone who wants to know and I'll share this video if they want to know more 😉
Thank you for sharing ❤ I appreciate you taking the time for an informed and personal take on your experience
Pleasure, thank you.
i just started this and i'm so hopeful it will help.
So informative ❤ 🙌
Thanks
I got it on prescription without any difficulty from my sleep doctor (i have sleep apnea).
When I had money, I was easily prescribed Modafinil for ADHD, as any other drug (scheduled) affected me adversely. I was forced to go on disability and instantly my new doctors refused to even discuss putting me on it, because even the generic is still more than Medicaid will pay. So, now I start projects all over my home, never finishing them. I sit and cry and feel worthless. This is no way to live. Even my volunteer work has stopped, as my racing thoughts don't slow down long enough for me to organize makeup, clothing, etc. Being on disability is tough enough without what little life I had being ripped away. It's really a terrible situation. I had been on a very low dosage for twelve years, so I certainly did not fit the profile of a drug seeker!
I heard the prescription with insurance is more expensive than the generic online buying
In my country it is dirt cheap and i have a service of selling generic meds, hit me up if you want modafinil
Couldn't you get it prescribed and then use GoodRX to afford it? That's what I do. It costs me $21 here in Texas for a 1 month supply.
FLmodafinil online and you don’t need a script.
If life is so difficult why don't you quit the medication?
I was just prescribed Modafinil. It is absoLUTELY a game changer for me. MS fatigue and foggy brain have been greatly reduced for me.
Thanks for the tips! 'Good ideas on how to get the most of one's daily dose. Best wishes to you, fellow MS warrior. (That's how I feel about all of us who face day-to-day challenges brought on by MS.)
Glad to hear!
Thank you for sharing
Great video I hope this helps people with MS. My Dr. (you know him well) always asks how I am doing, what things are difficult. I told him I no longer multitask well. I don't necessarily have cog fog but I do get distracted extremely easily. I can't listen to music while I work and my surrounding must be absolutely quiet. He said let's experiment and I tried a Provigil. I loved it! I could access my memory and my multitasking improved regardless of my surroundings. Felt like Bradly Cooper in Limitless. I am a bit funny about prescriptions I take them as little as possible. I kind of think the less I take them the more effect they will have when I do. Great video thank you for sharing
Modafinil is easily obtained in the U.K , goes under 2 Indian pharma labs , quid a pill , a lot of TRT users get it from the same source , great pre-workout when done with caffeine
TRT?
Testosterone Replacement Therapy (test injections ;)@@theMSguide
@@theMSguide Testosterone Replacement Therapy
@@theMSguidetestosterone replacement therapy, so steroids.
People use it as pre workout also?
Great Video
Thank you.
this guy should hop on TRT to bring back that young energy feeling
I’m this guy you refer to. In the UK there are v tough rx guidelines for male TRT therapy.
Are you advocating a gel, an injection or tablets? I am not anti I just know little about it.
Do you get it privately?
@@theMSguide injections 100%. The gels have a super low bio availability, nearly worthless
Are you in the UK? What should I ask for? Are they intramuscular or subcutaneous? How frequently do you take it? What is the name? Thanks.
@@theMSguide Nah im in the US, ive seen other youtubers post from Europe there ability to gain access to it through TRT clinics. Always intermuscular, you'll Cypionate from cottonseed oil. They will start you low then build you up in does. Try to get to 200 mg per week at the beginning. Ive been on it for 1.5 years and now self administer about 280 mg a week split in 2 doses
@@theMSguideFadgio Agrestis - 600 mg
Zinc - 50 mg
TongKat Ali. - 400 mg
Take everyday first thing in the morning
5 Days on
2 Days off
Get your testosterone checked before you start
Check it again 90 days later
I guarantee your testosterone will go up
And your testicles will get bigger
So if you feel some slight discomfort in them
Don’t worry
Just means it is working
Anthony Huberman has videos on this here on TH-cam.
It works well
Also when you get blood work done
Check total testosterone and free testosterone and also LH
I have very debilitating fatigue from brain cancer and think of asking for this. I still need to function at work and it’s nearly impossible the way things are.
Unless the doctor can tell you why it places you in imminent danger - not a tiny theoretical risk from a small trial - then ask them to record that you asked to try it, they denied it and the medical reason behind that denial.
@@theMSguide pretty sure they will write the script
Where's the best place to buy in the uk
Get it prescribed in the UK. The NICE guidance for treating MS lists Modafinil as an approved pharmacological intervention for fatigue. The guidance is NG220.
Thanks for the info. Do you know if you are still allowed to drive on it ? As it appears to be mainly prescribed (licences?) for narcolepsy
I believe yes you can - but probably worth ensuring the dvla have up to date records of all prescriptions when license is next reissued.
No driving restrictions.
Afaik there is no need to do that. It sure as heck isn’t something that impairs reaction times.
How many years have you been taking modafinil ?
7y now
@@theMSguide you take modafinil for 7 years Daily ???
Never been mentioned to me once, despite fatigue/cog fog being my biggest problem.
Are you in the UK? NICE list it as a fatigue therapy in MS these days.
@@theMSguide thank you. I am. I plan to leave a message for my MS nurse today.
See the end of this vid - Manage MS #fatigue. Dr Boster talks with theMSguide.
th-cam.com/video/FBvw3mCs88A/w-d-xo.html
Really appreciate the tip. My job requires a lot of mental acuity and often detailed analysis of large, dense text. These days, I open up a document and my heart sinks.
I was doing an MSc when a neuro recommended it. Utterly transformational. There are the yays and nays. Denial of t is puritanical nonsense. Now NICE mention it then any neuro who says no needs to be be sacked off. Drop me a line at dominic@theMSguide.com for more specific tips.
Dear Dom, thank you for this video. How did you know that Modafinil could help you? Did you have to do some tests at the clinic for example? I cannot buy this in Bosnia as it is not registered, however, if it is such a game changer as you say, I will ask my family members who live abroad if they can purchase it...
I didn’t know. A neurologist prescribed it without me asking for it. I know the students at university buy it from online pharmacies. Singapore I think.
@@theMSguide thx! My aunt in USA says she can not buy it without prescription. Gotta try something else. Take care!
Easy to get from online pharmacies…
its just 5dollars per 10tab of modalert 200mg in India
What dose of modafinil do you take? I tried 100mg for 2 days and didn't find any huge difference..
I take 200mg daily.
I take 400mg a day and 10mg Valium. I hope my doctor never stops prescribing me this because it has helped me tremendously with my mental health
Is it safe to take with an SSRI
I'm not a medic. I Googled 'drug interactions ssri and modafinil'
Try it out (the Googling) but when it all matters is speaking to whomever prescribed the ssri (of which there are many variations)bis the most important.
Yes. I am prescribed 400mg Modafinil and escitalopram. I recommend getting it through the do ctor instead of online. It's easy to get and generic is cheap.
@PwncakeOW which country are you in?
@@theMSguide hey bud. I'm in USA.
@PwncakeOW In my experience (USA), it's not so easy through a doctor. It can be done, and I have a script, but there are serious hurdles in the way. If I were doing it over, I would definitely just skip the doctor, hands down. Online it's relatively easy, but it's good to be discerning about the quality and reliability of the source.
It used to work for me but now it's not working plz reply?
Have you tried a drug holiday of a few days a week?
I took it for a while because of my ADD but it gave me a lot of headache's 😔
Consider looking into choline deficiency and headaches due to modafinil. Apparently alpha GPC can help a lot with headaches caused by modafinil
Did the modafinil help with the ADD at all before the headaches became an issue?
I have sleep apnea , I take 4 naps a day. Im concerned about driving long distance so I talked to my doctor yesterday about modafinil. She was very nasty to me. She treated me like a drug addict asking for drugs. She said nobody has EVER asked me for that. I am NOT going to prescribe you a CONTROLLED substance.
If you are in the UK it is most definitely not a controlled substance. It is prescriptible on an FP10. Ask any pharmacist. It says more about your doctor than you. They can start with 28 days of 100mg. She is just being obstructive. If you have MS then it is on the list of NICE approved Meds for MS fatigue.
I can get it for you man, hit me up it also cost much less where i live
I only take modafinil when i have a deadline. Does anybody feel fatigued the following day after taking modafinil?
I take it every day. Without I struggle b/c of the MS.
Yess once I left taking it ..there was obvious changes...coming back to.usual..focus we have
I am among those for whom it does not work at all - only negative side effects, the worst of which begin in the afternoon, after taking it in the morning. I don't sleep well the night after taking it, and still feel crappy the next morning.
Even during the morning hours after taking it, there's nothing positive about it. Just negative side effects, but not as negative as later in the day.
Caffeine plus L-theanine and L-citrulline are far better in my experience. So is guayusa tea. So is yerba mate. So are some of the pre-workouts (like Nutricost's).
I never experienced that. I was only on 100 mg. once per day.
brov coffee + modafinil you are frying your brain. I take 35mg as soon as i wake up, fasted. Thats the best way for me and ive tried every dose combined with coffee.
What is brov coffee?
@@theMSguide Hey! sorry for typo, i did not mean to type "brov", just coffee :)
I am 28 years old and my brain is younger than yours. Maybe this has to do something with it. I have been experimenting with modafinil for the past 4 years and I do love it. For some time, my ideal dose was 1 cup of coffee with 50 mg of modafinil. However, it became difficult to balance that with proper sleep , and I felt sometimes I would be very productive on the day I took it at the expense on the next day productivity / brain power.
I have found that less is more when it comes to Modafinil. Especially if you already mix it with caffeine. Taking it as soon as I wake up helps tremendously to have good night rest. I read somewhere that half-life of Modafinil is around 12 hours. It will stay in your system and wont let your brain rest at night. Thats my advice from personal experience :)
Nowadays, I only use it once a week, sometimes less. However, I might go on a modafinil cycle for higher productivity and focus on the remaining months of 2023.
I take it as soon as I wake up on an empty stomach* , the faster the body absorbs it, the better I can rest at night.
@045632 I have no problems sleeping. 8h usually.
I take 400 mg to stay up for 24-28 hours in a go, then 2.5/3 hours of sleep, then all over again. Yes i found tea / coffee + modafinil a best combination. Although I do take short nap of 10-20 mins before taking another dose of modafinil ( when power of 1st wears off) around once in every 8/10 hours. And that short nap makes me feel energetic again. At last, it's not only about modafinil, it's about will power, modafinil it's just a wakening agent, but to plan it, and willing to take it. Ultimately body recovers, pain also relives, but the only thing which we carry forever is our achievements and legacy.
How much do you take at once? And does your pee also smells funny?
200mg od and no!
@@theMSguide No? That is interesting, is it a 200mg slow release pill you are using? And what brand name is it?
I take 100mg Pils. From modiodal®
They are a bit like oval shaped tablets.
but they have a very weird sweet chemical taste!! And when it has gone through my system after about 4 hours i can smell It in my pee! 🤷🏻♂️😅
I have a fast metabolism so I need to take it again after 4 hours.
But maybe it's one of those smell's only people who can smell asparagus in there pee, can smell it?! 🤔🤷🏻♂️🤓
@TheOpticalFreak there is a half life for the Modafinil molecule so your rate of metabolic processing can’t change that.
In the UK a brand isn’t used as it is long out of patent protection. I know the most popular branded pull (exactly the same molecule) is ProVigil.
There is no SR preparation on the market here. I make a point of taking it on a full stomach which slows the release into the system.
It is my prop. It isn’t always perfect but I can sure tell if it don’t take it.
If your urine has an odour it could well be from all the inert binding and glazing agents in the pill and quite likely not the molecule.
Does the Patient Information Leaflet make any reference to this?
@@theMSguide i need to check the leaflet instructions, but I also had modiodal, modafinil, from a different brand/producer 100mg pills and it tasted the same. And I could also smell It in my urine after 4 hours! 🤷🏻♂️ so I really believe it is the molecule it self. But there is this thing that some people can't taste a certain bitter compound or smell asparagus in there urine! It has to do with your DNA wish I find really fascinating! 😃
@@theMSguideis armodafinil and Modafinil same
Bros tweeking rn
Old tweaker
Pmsl. You got the old bit right.
@@theMSguide😂
for many years i suffered from unknown tired and how to explain like very tired Need Lots of Rest after Rest you Feel Rest again Until my Doctor prescribe Modafinil.All my time spend for tiredness and rest Gone Hopefully no Side effects on Me.i really can do what i plan for my life from home working to outdoor works
where is the cheapest place buy modafinil w./.out script
No idea as I have it rx. However, I know many people buy it online. I’d stick to branded Provigil and shop around on the internet.
@StaceHalland ou probably think I am being vague but. Have no idea what you mean. 😢