Fluoroquinolones | 2nd vs 3rd vs 4th Generation | Targets, Mechanism of Action

แชร์
ฝัง
  • เผยแพร่เมื่อ 25 ก.ย. 2024

ความคิดเห็น • 135

  • @westfield90
    @westfield90 11 หลายเดือนก่อน +5

    Dad has pneumonia and they put him on 5 days of amoxicillin and azitromycin but that didn’t fully stop the fever and the infection came raging back. Now they started 10 day of levofloxacin and I’m praying this works. It’s really knocked him hard.

    • @westfield90
      @westfield90 10 หลายเดือนก่อน +5

      Update: The Levofloxacin seems to have worked well. The fever has stopped on day 4/10 and hasn't been there for 5 days since he finished the course.

    • @westfield90
      @westfield90 10 หลายเดือนก่อน

      @@rainycloud111 Thats quite a while ago now but I do remember it. It was a particularly stressful time in my life but I started getting vitiligo on the back my neck and the side of the temples. Small discolored patched that seemed to be growing in size. I actually took a Tyrosine supplement (My Dad had a health food store and I think I might have read Tyrosine was required to form Melanin) and I remember sitting under a bulb lamp for about 15 minutes close to those areas, for perhaps two weeks and sure enough the patches went back to normal. Of course I can't definitively say that is what cured it but I was very happy that it went away and hasn't been back since.

  • @orenoyume9849
    @orenoyume9849 2 ปีที่แล้ว +8

    I like how this channel makes a video that lists out important key points without making me feels jammed. it really helps!

    • @mandyhutch12
      @mandyhutch12 6 หลายเดือนก่อน

      Don't use these drugs they are poison and ruining people's lives. 💔 Look through the comments.

  • @acceptinglife6491
    @acceptinglife6491 4 ปีที่แล้ว +26

    your videos are amazing, too bad I only discovered them the day before my pharmacology exam

    • @antoninotroisi6585
      @antoninotroisi6585 4 ปีที่แล้ว +1

      never take it and give it search us Floxie in facebook

  • @jjmedicine
    @jjmedicine  4 ปีที่แล้ว +5

    Hey everyone - JJ, here once again! Thanks for all the views and comments on this video! If you haven't already please like this video if you liked it! And if you haven't already, please subscribe to this channel for more lessons like this one and to help support this channel. I really appreciate all of your support :)
    Check out more pharmacology lessons in the pharmacology playlist: th-cam.com/play/PLRjNoiRtdFwWPWcV9lZTh-Qxv0gYakQXR.html
    If you want to learn Medical Terminology (very helpful for science & medicine), please check out my lessons on that topic (my most popular lesson series): th-cam.com/video/04Wh2E9oNug/w-d-xo.html
    I know I haven't been the best at responding in the past, but I'm trying my best to respond to most comments now, so if you have any please leave your comment below.
    Take care, and keep in touch!
    JJ

  • @hopeiilv3690
    @hopeiilv3690 3 ปีที่แล้ว +3

    وننزل من القرءان ماهو شفاء ورحمة للمؤمنين ولا يزيد الظالمين إلا خسارا

  • @Erenmir
    @Erenmir ปีที่แล้ว +1

    Awesome video. Only one add on. Isn't the reason why we don't use moxifloxacin in UTIs the fact that it simply doesn't work? Because the elimination through kidneys is not enough? That's why it is not recommended usually.

  • @anthonygreenfield123
    @anthonygreenfield123 2 ปีที่แล้ว +2

    I also had tendonitis in my back, after just 3 pills 400 mg moxifloxacin. For an UTI

  • @alexisaac1554
    @alexisaac1554 2 ปีที่แล้ว +3

    I hate these compounds. Ruined my life adverse reaction is rough as heck but I had discitis I only wish I had used a different antibiotic very naive around these antibiotics. And what makes it worse I was prescribed it with out having a culture via bloods, and biopsy, I'm so angrey with the neglagance of the HNS in uk.

  • @SW-oo2jw
    @SW-oo2jw 5 หลายเดือนก่อน +2

    Causes ruptured tendons. Look it up!

  • @regevnava
    @regevnava ปีที่แล้ว

    What liver issues can this meds create. Can you please specify? Thanks

  • @ilaydamahmutoglu5942
    @ilaydamahmutoglu5942 2 ปีที่แล้ว

    you arre the best, I DON'T REALLY UNDERSTAND İN CLASS BUT YOU MADE ME LEARN IT WİTH FUN!!!! thank you!!!!!

  • @Phantastic_pharmacist
    @Phantastic_pharmacist ปีที่แล้ว

    Thanks for the video. M.catarrhalis is a gram positive diploccocus though

  • @informing_
    @informing_ 2 ปีที่แล้ว +3

    I have Enterococcus Faecalis prostatitis, I was given Cipro and after 7 days of it I took one dosage of Moxifloxacine, although cipro didn’t do anything when Moxi kicked in after 1-2 hours of taking I had nausea, then I stood up and I was fainting until I couldn’t see anything and very loud ringing to my ears and from then my nervous system acts weird I nervous all the time! What did I broke I think my mood is messed up from them

    • @informing_
      @informing_ 2 ปีที่แล้ว

      @@yakushimasu6316 Extremely dangerous

  • @angelrose4320
    @angelrose4320 4 ปีที่แล้ว +2

    Why ciproflaxin eye drops used in redness eye issues sometimes caused by allergy, what is the mechanism there...

    • @bartwilson2513
      @bartwilson2513 4 ปีที่แล้ว

      Ciprofloxacin is often paired with a corticosteroid to reduce the immune response. So the drops may contain both drugs and could be prescribed in the case of allergy, though there are better ways to treat allergies affecting the eyes.

    • @jintygm
      @jintygm 4 ปีที่แล้ว

      Never ever take a Fluoroquinolone will a steroid or NSAID. It is a horrendous combination.

    • @zachhamm3610
      @zachhamm3610 2 ปีที่แล้ว

      @@jintygm How kind of them to combine a fluoroquinolone with a steroid, feels like both my achilles are going to rupture for the past 5 weeks. And severe peripheral neuropathy, but at least 600mg gabapentin a day stops it.

  • @svenforstmann9608
    @svenforstmann9608 5 ปีที่แล้ว +20

    I am disabled by Fluoroquinolones (3 pills only !) since three years, sitting in a Wheelchair and unable to tolerate most medications. I am socially isolated and almost have no life thanks to fluoroquinolones.

    • @gdjdvydus2269
      @gdjdvydus2269 5 ปีที่แล้ว

      Sven Forstmann what happened?

    • @Weesa4
      @Weesa4 5 ปีที่แล้ว

      Omg that sucks, hope get better soon. But if it's possible can you elaborate?

    • @karimsanda8901
      @karimsanda8901 5 ปีที่แล้ว

      Which of them did you take ?

    • @docjnsn73a
      @docjnsn73a 4 ปีที่แล้ว +12

      I'm also suffering greatly from Fluoroquinolone Toxicity for the last 15 years. This is supposedly rare but the tens of thousands of people who suffer from these side effects would disagree. This doesn't include the potential link these drugs have to many different "autoimmune " diseases such as fibromyalgia, chronic fatigue syndrome, gulf war syndrome, ibs, crohn's and many others.
      Even worse is that most of us were prescribed these for minor infections where a safer drug would have worked

    • @recusa6519
      @recusa6519 4 ปีที่แล้ว +14

      Jeff Camsell I developed severe, sensory motor polyneuropathy after taking ciprofloxacin for a mild UTI. I now wear braces to walk and am likely going to be in a wheelchair before long. First symptom was stiffness in ankles and my reflexes disappeared. I was a runner and was very fit. This drug ruined my life. Please stop with the "science" and look at the results of prescribing a risky drug that literally kills an ant with a sledgehammer. And "some" nervous system reactions?!? You must be kidding.

  • @mkshorts_75p
    @mkshorts_75p ปีที่แล้ว

    If levofloxacin resistant in mdr tb. Then can we use moxifloxacin????

  • @dimmacommunication
    @dimmacommunication 9 หลายเดือนก่อน

    what if my bacteria is resistant to Levo and Cipro could Moxi be useful ?

  • @Columbariusify
    @Columbariusify ปีที่แล้ว

    very useful and clearly explained

  • @mkshorts_75p
    @mkshorts_75p ปีที่แล้ว

    Mdr tb mei levofloxacin resistant ho to moxifloxacin de sakte hai???

  • @bruttosporcoecattivo
    @bruttosporcoecattivo 4 ปีที่แล้ว +33

    Taking fluoroquinolones it's like playing Russian roulette. Never take these kind of drugs unless it's a life or death situation.

    • @qmi404
      @qmi404 3 ปีที่แล้ว +2

      I took them because of kidney infections. I recovered completely. My infection might come from my crown because I don't have other diseases.

    • @alexisaac1554
      @alexisaac1554 2 ปีที่แล้ว +4

      Yes exactly. Very dangerous

    • @bruttosporcoecattivo
      @bruttosporcoecattivo 2 ปีที่แล้ว +5

      @@alexisaac1554 Go try explain that to the doctors...

    • @alexisaac1554
      @alexisaac1554 2 ปีที่แล้ว +4

      @@bruttosporcoecattivo yeah good luck what makes me sick is that it was neglagance on there half I had a spinal injury and they suspected it to be discitis but this is where Nhs got it twisted 4 blood culture studies no cultures. One biopsy no cultures. But still sent me home with cipro and floxed me. No black box warning no telling me these are dangerous is crazy.

    • @bruttosporcoecattivo
      @bruttosporcoecattivo 2 ปีที่แล้ว +3

      @@alexisaac1554 Take my case : "suspected UTI". All the tests came out negative. He was sure I had no infection whatsoever, but he prescribed me a FQ, "just in case", to be sure...floxed at 30 years old, and in the best physical shape of my life.

  • @BilalAhmadkhan48
    @BilalAhmadkhan48 2 ปีที่แล้ว +1

    I watch every single clip of your channel but i m sad to know that you haven't made any video for "Nitrofurans" and i missed that topic and tomorrow will be my paper 😑
    BTW it's like side effect of being silent viewer 🙂

  • @akibferdaus2001
    @akibferdaus2001 3 ปีที่แล้ว +1

    Can I shift from 2nd generation to 4th generation? As my infection not going away

  • @1Bettina10
    @1Bettina10 4 ปีที่แล้ว +2

    Thank you so much for these! Helping me immensely with my pharmacology module!

  • @bellesky7377
    @bellesky7377 4 ปีที่แล้ว

    thanks a lot for brief explanation

  • @sarahward5974
    @sarahward5974 3 ปีที่แล้ว +1

    Really helpful thank you

  • @tahasaeed299
    @tahasaeed299 2 ปีที่แล้ว

    What type of BSC drug is ciprofloxacin??

  • @lydiafridah2629
    @lydiafridah2629 2 ปีที่แล้ว

    Amazing video. Thank you!

  • @markanthony2massaro692
    @markanthony2massaro692 4 ปีที่แล้ว

    Great video like away. Thanks you very much .!!!

  • @dimmacommunication
    @dimmacommunication 9 หลายเดือนก่อน

    Perfect for prostatitis with E.faecalis

  • @dhanvantarihealthcare6084
    @dhanvantarihealthcare6084 2 ปีที่แล้ว

    Best scientific and very useful infimetion for medical practionars

  • @farzandalikhan5933
    @farzandalikhan5933 29 วันที่ผ่านมา

    Yall it caused me tendonitis in my hip and shoulder and it also caused me to have eye floaters. And it also gave me stripes marks

  • @antonela478
    @antonela478 2 ปีที่แล้ว

    Very good , joyita

  • @rebbekandahuma2173
    @rebbekandahuma2173 ปีที่แล้ว

    wow, thank you so much.

  • @prabeshkarmacharya9755
    @prabeshkarmacharya9755 5 ปีที่แล้ว +1

    Thanks

  • @eyeYT
    @eyeYT 2 ปีที่แล้ว

    thanks very much!

  • @ormikadubey4273
    @ormikadubey4273 ปีที่แล้ว

    Referred three books , none helped me this much

  • @SAIFALI-br3qc
    @SAIFALI-br3qc 3 ปีที่แล้ว +1

    Very much helpful.....

  • @maamulahayoutube-wr65
    @maamulahayoutube-wr65 7 หลายเดือนก่อน

    Very good ❤😊

  • @acksonmunshya2696
    @acksonmunshya2696 2 ปีที่แล้ว

    Thank you

  • @sandywhat2429
    @sandywhat2429 3 ปีที่แล้ว +2

    People with Ehlers Danlos Syndrome and connective tissue disorder CANNOT take fq's.

  • @Eire4life
    @Eire4life 8 หลายเดือนก่อน

    Here’s a bit of good info, these quinolone (if given to anyone withdrawing from benzodiazepines)antibiotics, will make the withdrawal worse as it effects the same receptors)

  • @pizza40421
    @pizza40421 2 ปีที่แล้ว

    How do you structurally distinguish a second generation from a third generation from a fourth generation quinolone?

  • @salvatore.M77
    @salvatore.M77 2 ปีที่แล้ว

    Helpful, thank you ❤️

  • @afnanm9564
    @afnanm9564 6 หลายเดือนก่อน

    Perfeect!

  • @lucid212
    @lucid212 5 ปีที่แล้ว +1

    you are great!

  • @CherryDolce93
    @CherryDolce93 4 ปีที่แล้ว +13

    Adverse reactions are at 7:50 - please do not ever take these drugs, I’m speaking from personal experience

    • @peacefinder9557
      @peacefinder9557 4 ปีที่แล้ว

      Enz Di Cristofaro what happened to you ??

    • @bartwilson2513
      @bartwilson2513 4 ปีที่แล้ว +3

      All drugs have side effects and prescribing physicians assess risk vs. harm for every patient. This is bad advice. You are telling someone with an infection that only this class of drug works (or is the only one available) not to take it? Even though the side effect of not taking it is death? I know someone who almost died because they took a baby aspirin (80mg).....should everyone never take aspirin because of my friend’s experience?

    • @jintygm
      @jintygm 4 ปีที่แล้ว +2

      @@bartwilson2513 You really need to look into this class of drugs. Around 8 Black Box warnings from FDA !!! Only to be used in life or death situations when all others have been tried. Cipro is a failed Chemo drug. Highly toxic. Have a look on You tube at Rx PillD or on Facebook groups for Fluoroquinolone Toxicity/damage and tell the millions worldwide whose lives have been shattered that they should still have taken them. Oh that includes Doctors. Check out Dr Ghalili.

  • @eppystein2953
    @eppystein2953 4 ปีที่แล้ว +9

    Death-medicine

  • @ተፈጥሮ
    @ተፈጥሮ 2 ปีที่แล้ว

    Ciprofloxacin is safe for less than one year?

    • @kovacsmagdolnajulia
      @kovacsmagdolnajulia 2 ปีที่แล้ว

      Egy szemtől meghalhatsz

    • @adelnajjar1779
      @adelnajjar1779 11 หลายเดือนก่อน

      It's not safe at all, even one pill can make you disabled for the rest of your life

  • @moonoom764
    @moonoom764 4 ปีที่แล้ว +24

    dont take these!!

    • @zachhamm3610
      @zachhamm3610 2 ปีที่แล้ว +5

      Yup, never been so fucked up, pray I heal everybody

    • @zachhamm3610
      @zachhamm3610 2 ปีที่แล้ว +1

      Also the EAR DROPS DID THIS TO ME! The stupid white coats will gaslight you saying you're crazy because the FDA hasn't blackboxed ear drops (yet). They will refuse gabapentin and make you literally insane with neuropathy so severe that it feels like your hands and feet are on fire. I had to go to the street for GABAPENTIN!

    • @moonoom764
      @moonoom764 2 ปีที่แล้ว

      @@zachhamm3610 So sorry to hear that! is Gabapentin helping you?

    • @zachhamm3610
      @zachhamm3610 2 ปีที่แล้ว +1

      @@moonoom764 It stops the neuropathy, but the tendonitis is bad too unfortunately.

    • @Lover9420
      @Lover9420 ปีที่แล้ว

      If levofloxacin is resistance in mdr tb. Can i use moxifloxacin

  • @hopeiilv3690
    @hopeiilv3690 3 ปีที่แล้ว +2

    أعوذ بالله السميع العليم من الشيطان الرجيم

  • @odjdksljsktaywhsjak9253
    @odjdksljsktaywhsjak9253 3 ปีที่แล้ว

    بسم الله الرحمان الرحيم

  • @hemmel777
    @hemmel777 3 ปีที่แล้ว +1

    He's canadian

  • @KEire1916
    @KEire1916 2 ปีที่แล้ว +1

    12 pills 💊 and I'm ruined

  • @venkybly
    @venkybly 4 ปีที่แล้ว +1

    Tq

  • @C-130-Hercules
    @C-130-Hercules 2 ปีที่แล้ว

    Moxifloxacin gave me small fiber neuropathy. ☠️

  • @Malath98
    @Malath98 2 ปีที่แล้ว

    😭😭😭😭😭

  • @shwetadubey1546
    @shwetadubey1546 4 ปีที่แล้ว

    Sir please suject me,my urien culture report,puscell 5-6/hpf, ecoli 37*c,,I tack docter According, Moxifloxacin an surup alkasol but not efacted me,please suject me a Moxifloxacin combination to me ,my report according an my 13 year old girl child, ecolie infaction ,please🙏

  • @marwayahya6347
    @marwayahya6347 7 หลายเดือนก่อน

    Couple if mistakes in ur presentation

  • @Lover9420
    @Lover9420 ปีที่แล้ว

    If levofloxacin is resistance in mdr tb. Can i use moxifloxacin