Friedel-Crafts Alkylation

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  • เผยแพร่เมื่อ 18 ธ.ค. 2024

ความคิดเห็น • 163

  • @roxx_ve
    @roxx_ve 6 ปีที่แล้ว +44

    Thank you so much! I'm a second semester organic chemistry student, and I've watched several of your videos to help me with homework and tests.

  • @glendamacco4764
    @glendamacco4764 7 ปีที่แล้ว +77

    currently pulling an all nighter for an o chem test tmrw at 8 am. just started watching your channel, you're the bomb!

  • @Iklilledurhamster49
    @Iklilledurhamster49 8 ปีที่แล้ว +516

    all hail chemistry jesus

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 ปีที่แล้ว +321

      thank you, my son.

    • @hamedhosseini4938
      @hamedhosseini4938 8 ปีที่แล้ว +10

      HAAHAH so true :DDDD

    • @andriansmith3142
      @andriansmith3142 7 ปีที่แล้ว +9

      A miracle worker indeed. You saved 3 organic courses of mine :P (pun intended). You show the one true path to graduation :P

    • @elafm2344
      @elafm2344 7 ปีที่แล้ว +1

      F

    • @cpn6464
      @cpn6464 4 ปีที่แล้ว +11

      Makes more sense to worship a worldly genius than a mythical sky god.

  • @unslashed
    @unslashed 8 ปีที่แล้ว +12

    You are the real hero. I'm so glad that I discovered your channel before it was too late. (have the final on 16th of december and all the slides are in French, coz they just added organic chemistry to the program, polymer science master Strasbourg-Freiburg, and the only professor with terrible English teaches organic chemistry) you are my savior

  • @moribnd
    @moribnd 7 ปีที่แล้ว +12

    Thanks, Dave. Short and to-the-point.

  • @Umbriel92
    @Umbriel92 ปีที่แล้ว +10

    A legend was born

  • @TiedAlpaca00624
    @TiedAlpaca00624 2 หลายเดือนก่อน +3

    And thus, a legend was born. Destined to get yelled at by James Tour, take on many challenges such as flat earth, electric universe, young earth creationism, and having to repeat basic scientific observations 50 times only to get demonized.

  • @twinnerNet
    @twinnerNet 28 วันที่ผ่านมา

    It's neat to see your evolution over time. The science heavy teacher stuff is great. The no nonsense frank debunker stuff is great too. I look forward to another nine years and more of your lessons.

  • @shakatapuramshrividya1148
    @shakatapuramshrividya1148 10 ปีที่แล้ว +12

    woah,man,this is good. I told a coupla my friends already!

  • @Daniel-nu8uk
    @Daniel-nu8uk 10 ปีที่แล้ว +7

    Perfectly explained.Where have you been bro for all these years??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  10 ปีที่แล้ว +32

      Teaching in the flesh! But now it's time to share the wealth with the people. Please spread the word!

    • @GamingForeverEpic
      @GamingForeverEpic ปีที่แล้ว +2

      @@ProfessorDaveExplains your old

    • @RAJ_GADHAVI
      @RAJ_GADHAVI ปีที่แล้ว +2

      Bro you are the first commenter on this channel 😂

    • @TylerTMG
      @TylerTMG ปีที่แล้ว +1

      @@RAJ_GADHAVI no he's not it's way later
      Just because it's the first comment on the first video doesn't mean it's first

    • @blagoevski336
      @blagoevski336 11 หลายเดือนก่อน +1

      ​@@TylerTMGnigga what

  • @AlecuBeldiman68420
    @AlecuBeldiman68420 2 ปีที่แล้ว +7

    And so, a legend was born

  • @adeshvinod4748
    @adeshvinod4748 9 ปีที่แล้ว +9

    You sir are a savior!
    Extremely well done, Dont stop making more☺

  • @massrdmdoer7348
    @massrdmdoer7348 10 หลายเดือนก่อน

    man I love chemistry, my school teacher told me not skip ahead with material as to not overwhelm myself, but I simply enjoy the subject

  • @martinweiss5355
    @martinweiss5355 7 ปีที่แล้ว +1

    Realy helpful thx. I´m from germany and there was no problem understanding you. So well done !

    • @martinweiss5355
      @martinweiss5355 7 ปีที่แล้ว

      Anyone an idea about the +M - effect ? Its relevant for my Test tomorrow.

  • @LexoG33
    @LexoG33 7 ปีที่แล้ว +2

    That's a cool tattoo Professor Dave. Now I know how a parsec is defined!

  • @IsmailAhmed_Ishydadon
    @IsmailAhmed_Ishydadon 7 ปีที่แล้ว +16

    Not all heroes wear a cape. This is showing up on my exam next week and you just saved my ass. 👍 👍 👍

    • @melancall5960
      @melancall5960 3 ปีที่แล้ว +1

      Pass the exam?

    • @IsmailAhmed_Ishydadon
      @IsmailAhmed_Ishydadon 3 ปีที่แล้ว +3

      @@melancall5960 damn this was 4 years ago. I did pass and graduated almost 1.5 years ago 😂

    • @user-eh9lc4wp2c
      @user-eh9lc4wp2c ปีที่แล้ว +1

      ​@@IsmailAhmed_IshydadonHi pal, what are you pursuing now? I'm just curious

  • @sanjoosona
    @sanjoosona 4 ปีที่แล้ว +7

    Sir now u have 1million subs
    🔥🔥🔥👍👍🙏
    Keep it down👍👍👍

    • @Garrettmoron
      @Garrettmoron 9 หลายเดือนก่อน

      Yeah, because he can’t do anything apart from making yt vids.

  • @Riyuihein
    @Riyuihein 10 หลายเดือนก่อน +1

    I ma here before my exams 😭 thank you so much sir

  • @Nikkunj
    @Nikkunj ปีที่แล้ว +1

    thank you very much sir,I am a class 11 student and this video really helped me

  • @samlal3618
    @samlal3618 3 ปีที่แล้ว

    Thank you so much you have NO idea how much your saving me right now

  • @brandonswritingservices7787
    @brandonswritingservices7787 5 หลายเดือนก่อน +16

    Who is here in 2024?

    • @kalidd1899
      @kalidd1899 หลายเดือนก่อน

      Yo

  • @dubola5777
    @dubola5777 6 ปีที่แล้ว

    Short and to the point, i like it! Thank you!

  • @therevprogamers
    @therevprogamers 6 ปีที่แล้ว +2

    Awesome explanation , thanks for it

  • @mireamema162
    @mireamema162 5 ปีที่แล้ว +2

    Yor are reallly incredible and a lifesaver(THANK YOU) Although I do have a question: Does a multiple substitution happen here?

  • @karenopt
    @karenopt 4 ปีที่แล้ว +1

    Also, when is rearrangement needed for Electrophilic Aromatic Substitution?

  • @Kiky_MedPhysicist
    @Kiky_MedPhysicist 3 หลายเดือนก่อน +1

    So, this is how the legend was born 🫡

  • @ramashamyleh9431
    @ramashamyleh9431 5 ปีที่แล้ว +1

    Thanx prof.
    All respect for u

  • @pleaseunsubscribeme8533
    @pleaseunsubscribeme8533 4 ปีที่แล้ว +2

    Y amine doent undergo fridel craft alkylation? Is there any other compounds other than amine and phenol?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 ปีที่แล้ว +4

      the group with a lone pair will interact with the lewis acid catalyst before the alkyl chloride has a chance to

  • @gehtdinixan1935
    @gehtdinixan1935 7 หลายเดือนก่อน

    where does the H comes from at 2:45? that is also attached to the ring next to the alkyl fragment

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 หลายเดือนก่อน +7

      every carbon in a benzene ring has one hydrogen, they are just implied unless needed for the mechanism

    • @gehtdinixan1935
      @gehtdinixan1935 7 หลายเดือนก่อน

      Stupid me ugh, thanks!

  • @saintofchelseathomascarlyl5713
    @saintofchelseathomascarlyl5713 6 ปีที่แล้ว

    i love the new intro

  • @a_nuraqilahbintikhairul1353
    @a_nuraqilahbintikhairul1353 4 ปีที่แล้ว

    thank you professor Dave

  • @exoinvadedmymind1006
    @exoinvadedmymind1006 5 ปีที่แล้ว

    What's the limitations I don't get them do u have a video of them 😭😭 polyalkylation and carbocation rearrangement

  • @hamedhosseini4938
    @hamedhosseini4938 8 ปีที่แล้ว

    Professor is a big lad.

  • @Jorge-sv6pk
    @Jorge-sv6pk 8 ปีที่แล้ว +1

    you're the man

  • @karenopt
    @karenopt 4 ปีที่แล้ว

    Why do we restore aromaticity? What is the significance?

  • @MiddleTN_Cubaris
    @MiddleTN_Cubaris 6 ปีที่แล้ว

    You are clutch, my good sir

  • @krishnapanigrahi2235
    @krishnapanigrahi2235 7 ปีที่แล้ว +1

    thank you so much

  • @lovedavis7376
    @lovedavis7376 8 หลายเดือนก่อน +1

    All hail chemistry Muhammad. Just discovered the channel.Im learning so many new things . Thank you for taking the time out to post

    • @knoobiez
      @knoobiez 6 หลายเดือนก่อน

      Ur going to hell

  • @medifectious
    @medifectious 9 ปีที่แล้ว

    You see how you said chlorine has 6 valence electrons and aluminium has 4 valence electrons should the chlorine not be negative because it has more electrons. If not why is that? It's at 1:15

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 ปีที่แล้ว

      Random Help In the catalytic complex, chlorine will have a formal positive charge because it's showing 6 electrons in the lewis dot structure, one per bond and two lone pairs, compared to its typical valence of 7. One fewer electrons means a positive charge. Aluminum shows 4 electrons, one per bond. Its typical valence is 3 so this has a formal negative charge.

    • @medifectious
      @medifectious 9 ปีที่แล้ว

      You mean one lone pair right or there would be 8 valence electrons 0-0

  • @anshumaanshukla7443
    @anshumaanshukla7443 5 ปีที่แล้ว +1

    sir, do u have any videos that might help me with understanding the +m effect?

    • @Kurosaka
      @Kurosaka 3 ปีที่แล้ว

      the mesomeric effect? hmm

    • @user-eh9lc4wp2c
      @user-eh9lc4wp2c ปีที่แล้ว

      ​​@@Kurosakayeah

  • @muramasa7537
    @muramasa7537 5 ปีที่แล้ว

    Nice ! My book had only 1 line n the figures n didnt understand but now after watching this i do !

  • @kuntalkoley3107
    @kuntalkoley3107 6 ปีที่แล้ว

    Sir, what you are discussing is Friedel craft alkylation. Have you made any vedio on acylation?

  • @rassimsimou1594
    @rassimsimou1594 10 หลายเดือนก่อน +1

    Good

  • @Shugenjya
    @Shugenjya 8 ปีที่แล้ว

    Thanks for the explanation, But i have a question. Why does the chloroalkene wants do bond with the AlCl3?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 ปีที่แล้ว +2

      just a Lewis acid-base reaction! chlorine's got lone pairs, aluminum is electron-deficient.

    • @ashutoshdash5965
      @ashutoshdash5965 ปีที่แล้ว

      What are you doing now brother

  • @songohan393
    @songohan393 5 ปีที่แล้ว

    Thank you

  • @tiannamurray792
    @tiannamurray792 6 ปีที่แล้ว

    Hello Do you have a video for Friedel-Craft Acylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  6 ปีที่แล้ว +3

      nope but it's essentially the same reaction just with an acid chloride instead of an alkyl chloride!

  • @lauravaranasi6911
    @lauravaranasi6911 3 ปีที่แล้ว +1

    helpful!

  • @rygalindo
    @rygalindo 7 ปีที่แล้ว

    If the benzene ring already has a substit. group on the ring that does not prevent the reaction, I'v been told that it adds to the meta position, is this correct?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 ปีที่แล้ว +1

      the regioselectivity of an electrophilic aromatic substitution reaction on a monosubstituted ring depends on the identity of the substituent, check out my clip on o/m/p directors!

  • @sulafaalsammarraie9681
    @sulafaalsammarraie9681 5 ปีที่แล้ว +1

    You are the besttttt love you my lifesaverrrrr

  • @bryannabueno2064
    @bryannabueno2064 3 ปีที่แล้ว +2

    why am I payin all this money for school and learn nothing but TH-cam is free

  • @Aadi129
    @Aadi129 ปีที่แล้ว

    What are hybrid orbitals of phenol amine tetra di phosphate ????

  • @julianlidberg7590
    @julianlidberg7590 3 ปีที่แล้ว +1

    I´m writing my exam from home while watching this xd

  • @abd2002
    @abd2002 3 ปีที่แล้ว +1

    First video? 😮

  • @stickanimation9888
    @stickanimation9888 11 วันที่ผ่านมา +3

    You are coming from the last video

  • @namanemo5591
    @namanemo5591 5 ปีที่แล้ว

    Love you prof ❤️

  • @fatimaalkwndy9673
    @fatimaalkwndy9673 ปีที่แล้ว +2

    but what is the difference between this and halogenation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  ปีที่แล้ว +3

      this is alkylation

    • @fatimaalkwndy9673
      @fatimaalkwndy9673 ปีที่แล้ว

      like if I had a question on the test that says to explain the mechanism of the reaction with the same catalytic complex that we used in the halogenation how would I know its not Friedle reaction? I know my question is kinda stupid but I have a test tomorrow and I am soooo nervous

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  ปีที่แล้ว +3

      @@fatimaalkwndy9673 alkylation will require an alkyl chloride, so R-Cl + AlCl3 you know it is alkylation

    • @fatimaalkwndy9673
      @fatimaalkwndy9673 ปีที่แล้ว +2

      thank u sssso much sir you're life savior

  • @mohammadasifkhan3087
    @mohammadasifkhan3087 9 ปีที่แล้ว

    why hydroxylation take place at the end of Friedel craft acylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 ปีที่แล้ว

      +Asif Khan Mohammad no hydroxylation, there's a carbonyl group that was already present in the acyl chloride.

  • @abhishekchunduri8285
    @abhishekchunduri8285 8 ปีที่แล้ว

    Sir, and why can't Vinyl halides and Aryl halides undergo Friedel Crafts Alkylation..whereas...a double bond involving molecule like Acyl group..undergo Fridel Craft Acylation..??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 ปีที่แล้ว +1

      it's because friedel-crafts alkylation involves the formation of a carbocation on the alkyl fragment as an intermediate in the mechanism, and carbocations are highly unlikely to form on sp2 carbons.

    • @abhishekchunduri8285
      @abhishekchunduri8285 8 ปีที่แล้ว

      Thanks

  • @jeff-freehoke8012
    @jeff-freehoke8012 6 ปีที่แล้ว +7

    There was no music. wtf

  • @abdulbasitkhan2589
    @abdulbasitkhan2589 8 ปีที่แล้ว +1

    can we use Iodine in this

  • @rayyvon18
    @rayyvon18 8 ปีที่แล้ว +2

    Can you make a video on acetylation?

  • @lauravaranasi6911
    @lauravaranasi6911 3 ปีที่แล้ว

    very helpful**

  • @broccoli1020
    @broccoli1020 5 ปีที่แล้ว +1

    the question is how much should AlCl3 be used in this reaction?

  • @MuhammadHamza-fl7rn
    @MuhammadHamza-fl7rn 7 ปีที่แล้ว +1

    please use full representation its hard to understand those I'm not saying I don't know that but its easy the other way

  • @Smaileymaile
    @Smaileymaile 6 ปีที่แล้ว

    What's the difference of alkylation and aceylation

  • @abhishekchunduri8285
    @abhishekchunduri8285 8 ปีที่แล้ว

    Sir, can u please do a video on Friedel Crafts Acylation??..it really is confusing ...only u can explain it in a crystal clear way...

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 ปีที่แล้ว +3

      it's very similar to the alkylation! you can google the mechanism and email me if you have any questions.

  • @saptarshisahoo5075
    @saptarshisahoo5075 9 ปีที่แล้ว

    Can anybody explain me mechanism of Blanc chloromethylation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  9 ปีที่แล้ว +1

      +Uzumaki Saptarshi the oxygen interacts with the zinc atom to form an oxonium species, which is highly electronegative. this intermediate is what the arene reacts with.

  • @tastethejace
    @tastethejace 10 หลายเดือนก่อน

    God this makes law school seem so easy in comparison lol

  • @ankushvasireddy8871
    @ankushvasireddy8871 4 ปีที่แล้ว +4

    This day marks the birth of Jesus

  • @bw6329
    @bw6329 3 ปีที่แล้ว +2

    May Allah bless u

  • @ballights445
    @ballights445 3 ปีที่แล้ว

    5 years later...

  • @Eric-sq4hd
    @Eric-sq4hd 4 ปีที่แล้ว

    don't you mean chlroine is contributing 6?
    therefore has a +1
    well done. only video on this done in 3 min.

  • @chem.chemistry1122
    @chem.chemistry1122 3 หลายเดือนก่อน +1

    🎉

  • @nishalgoud2286
    @nishalgoud2286 9 ปีที่แล้ว

    how to study organic chemistry for jee mains

    • @capturexproductions5958
      @capturexproductions5958 5 ปีที่แล้ว

      Kitni rank aayi?.. konsa college mila

    • @RAJ_GADHAVI
      @RAJ_GADHAVI ปีที่แล้ว

      Bro you are the true learner from 2016 😂😂

  • @dallincarroll
    @dallincarroll 8 ปีที่แล้ว +1

    Dude, you look like Said from Lost.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  8 ปีที่แล้ว +3

      never saw it! i hope he is handsome.

    • @TheSaddestCodPlayer
      @TheSaddestCodPlayer 8 ปีที่แล้ว +2

      He's gorgeous, definitely a close second to Dave. Unfortunately, Said just doesn't know enough Ochem to keep me watching him everyday. Dave doesn't have that problem; he's too busy solving mine!

    • @hamedhosseini4938
      @hamedhosseini4938 8 ปีที่แล้ว

      Haha nah professor is Italian origin, said is Indian origin.

  • @arnoldstephen5668
    @arnoldstephen5668 5 ปีที่แล้ว +4

    anybody 2019

  • @pri173
    @pri173 9 หลายเดือนก่อน +1

    I think he looking like ranveer kapoor😅

  • @SchizoaffectedGamer2112
    @SchizoaffectedGamer2112 4 ปีที่แล้ว +1

    What ?

    • @sanjoosona
      @sanjoosona 4 ปีที่แล้ว +1

      😂😂😂😂

  • @nirapsingh9773
    @nirapsingh9773 2 ปีที่แล้ว +1

    Professor please seach this vieo up and explain this , type quantm computer and jinn demons in youtube .

  • @MeganWatson-qg7oh
    @MeganWatson-qg7oh ปีที่แล้ว

    ilyyyyyyyy

  • @elyaazmi8863
    @elyaazmi8863 4 ปีที่แล้ว

    Sir, Can you just translate to indonesian, im not be able to speak english well

  • @juanananth
    @juanananth 6 หลายเดือนก่อน +1

    Jesus?

  • @aabhamahawar770
    @aabhamahawar770 6 ปีที่แล้ว

    Pure Indian lgta h

  • @microman_mathtiiaasrosen
    @microman_mathtiiaasrosen ปีที่แล้ว +1

    close this channel

  • @9691ark
    @9691ark 3 หลายเดือนก่อน

    I'll bet this whatever it us can't even change a tire!😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂😂

  • @avelandara3823
    @avelandara3823 ปีที่แล้ว +1

    thank you