Lp(a) 101 Webinar
ฝัง
- เผยแพร่เมื่อ 1 เม.ย. 2021
- Lipoprotein(a), or Lp(a), is an important genetic risk factor for heart attacks and strokes. Join us for our Lp(a) 101 webinar. Dr. Mary McGowan, Chief Medical Officer of the FH Foundation, will present the latest guidance and answer your questions including:
- What is Lipoprotein(a)?
- What high Lp(a) means for heart disease risk, including heart attacks and strokes?
- How Lp(a) is inherited?
- How you can get tested?
- What you should do if you or your family member has high Lp(a)?
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www.thefhfoundation.org
Cardiologists really need to get up to speed on this. I recently had a CAC scan done and advanced lipid panel. I learned that my LDL was elevated and I have an LPa of 234 nMol/L. High.
Because my CAC was zero, I’m only 47, lean, and other markers on my blood work looked good, my cardiologist said I was low risk and didn’t worry about any strategies to bring down the LPa.
But it sounds like having a clear CAC is only one factor in assessing whether LPa is doing damage …. and ANY calcium is bad so I feel like I’ve been given a clean bill of health while I really have a ticking time bomb.
Maybe LPa is doing no damage.
A discussion on Lp(a) without acknowledging pioneers Linus Pauling and Matthias Rath is to be viewed with question of motive.Protocol been out for decades to treat this.Dropped by BP 40 points in a month
Carl Clark 👍🏻 thank you for pointing that out.
Agree. It reduced my lpa 25% in about a month.
@@Kiki-sl1ro c,mcmcjj
How is it possible that Lipoprotein (a) is bad when there are many articles on Pubmed that say Centenarians also have elevated levels of Lp(a) that could be in the genetics for a good reason as to be protective for the body and a long healthy life? Please explain.
hey, my lpa is 127 mg and I am very keep to be a part of phase 3 trial. want to know whether there is any centre in India as a part of trial ?????
49:53 Q&A
50:45 Why do you think there is such a lack of awareness for Lp(a) within the medical community?
52:30 Why does Lp(a) treatment focus on lowering LDL cholesterol?
And if Lp(a) is not lowered enough while on a treatment, why should the treatment be continued?
54:20 Is there a specific goal in mind with Lp(a) & LDL therapies?
55:27 Are there particular tests one can take to assess their risk?
57:03 What if the coronary calcium score is zero?
58:30 What age would you recommend offspring of a parent with high Lp(a) get tested for Lp(a)?
59:06 How does the FH Foundation get their data?
1:01:53 Why are aortic valves impacted by Lp(a) but not other valves such the mitral valve?
1:02:30 Does anyone know if you measure a direct LDL, is the Lp(a) also included?
How available and expensive is the Lp(a) test?
1:03:32 If you have larger Apo(a) which results in lower Lp(a) concentration, does the risk of heart disease decrease?
1:04:47 Will people affected with an elevated Lp(a) see a reduction in LDL when treated with antisense oligonucleotides?
1:06:09 Why statins?
1:07:52 Does someone with high Lp(a) always have high cholesterol? And at what levels should they be tested?
1:09:15 Are there any other symptoms of high Lp(a) besides heart attack or stroke?
1:10:26 How often should Lp(a) be checked?
1:11:45 What is the overlap between familial hypercholesterolemia (FH) and Lp(a)?
How can women manage elevated Lp(a) post-menopause?
1:13:25 What about teenagers and young adults with high Lp(a)?
1:14:50 Can you go too low with LDL cholesterol?
Can multiple treatments be used?
1:16:30 (wrap up)
Niacin is said to lower LP(a). Linus Pauling claimed that LP(s) evolved as an emergency mechanism to repair an arterial wall falling apart because of collagen degradation caused by a chronic Vitamin C deficiency. If Pauling was correct, wouldn't it be disastrous to block LP(a) if a person fails to consume adequate Vitamin C?
He’s not correct
@@bigbobabc123 Has it been disproved?
@@tonyclarke3580 those who make statements need proof. There’s a reason no researchers recommend this approach
@@bigbobabc123 Understood. I thought one possible explanation is that nobody would fund such a trial since there is no money to be made.
Michael Williams my LP-a is elevated & I’ve been suggested & am taking HDVC therapy for the same. VitC is a miracle molecule.
Thank you so much for this amazing presentation..🙏🏼 I hope my questions could be answered.. 😊
1-should we test at different labs for the lp(a)? I saw in a previous presentation that depending on the lab, the results could vary.
2-could lp(a) be passed down from a grandparent, in other words if grandma had it, daughter does not, will that child automatically not have it? Of course as long as the father of the child does not have the genetic predisposition as well..
3-should an lp(a) of 139 nmol/L with an LDL of 94 mg/dL in a menopausal woman in her 50s be treated eventually if the LDL stays under 100 mg/dL? Stress test and calcium score were both normal. Ca score 0.
Thank you if they could be answered that would be great..
I will go on the website and FB as well.
My LPa is 90noml im 38 and cardiologist said i have slight aortic valve stenosis. He said i was born with it
Niacin and oat bran 🙏🤗
It's the medication for the lipoprotein a high level?
@@user-gy5ez1qz5d Niacin is a vitamin. Depends on the need of the person. In his book the "8 Weeks CHOLESTEROL CURE " Kowalski stated he takes @ 3mg divided up during the day. He strongly recommends eating oat BRAN! because of the soluble fiber. I only need 1/3 @ 1000 mg. For at least 5 years it has worked thus far for me. And I eat oat BRAN most days. I always recommend any person to check with their health care provider because who knows someone may be allergic to oats or gluten even have negative reaction to vitamin. I'm not a medical doctor. Best of health to u and yours😇🙏 O yes, the niacin not only lowers my cholesterol but also my Lpa. I only am sharing my personal experience and a book that helped me.
Interesting that she says Niacin lowers by 20% but she doesn’t use it per her cited list of side effects, but she enthusiastically embraces statins which raise LPa and she lists no side effects. I thought statins had considerable side effects.
My Lpa was 173 mmol/L. I have managed to reduce it to 130 mmol/L after using slow released Niacin 1000 mg/day.
My 10 years old baby daughter has 490 mmol/L I have got her heart checked and seems be fine. She's been referred to Lipid specialist. Her Lipid numbers are so high. I am giving her 250+260 mg Niacin daily along with high dense DHA
How can I send you messages private please i have 375 rate of lipoprotein a
I don't know what to do
@@user-gy5ez1qz5d try niacin and vitamin c megadose
Mine is 273, I don't care.
@@Notme-tq4xshi
At 39:55, you said the we know by clinical studies that for every 40 milligram reduction in LDL, presumably from the use of statins, will lower future cardiovascular events by 20%? I have two questions, 1. 20% relative to what? and 2 What studies or proof?
I would like to see it. I never heard that before.
20% of baseline
She also said they were observational studies. Not a clinical trial then.
Mine is pretty consistent, above 450 for years
I have 8 stents now
One massive heart attack 10 years ago at 39.
How do I sign up for these trials
This is not correct - lp(a) increases CVD because the protein ap(a) carried on Lp(a) prevents blood clots BREAKING UP.
Its not about cholesterol "clogging up" arteries.
Is there any proof you can cite that LP(a) is bad? Please do.
Hi I'm 61 years old and have gene determined high Lp(a). It was 403mg/l in 2012 and 400mg/l this summer. Yesterday I had a scan and feared a dead sentence. However the outcome was quite positive. I have very litle to no plaque. Only 3% at my age have less plaque I was told. My cardio age was judged to 34-39 years! I'm quite healthy and my triglyceride have been low the few times measured, which should hint I'm metabolic healthy. Maybe that's what matters? Not the level of cholesterol or Lp(a)?
Hey hi ! Only LP ( a ) levels are high? What about LDL levels ?
Lp(a) increases CVD because the protein ap(a) carried on Lp(a) prevents blood clots BREAKING UP.
Its not about cholesterol "clogging up" arteries. The danger lies in that if you happen to get a blood clot
then the Lp(a) in the blood stops a clot breaking up, then a large clot causes the attack.
(I believe recent drugs can lower the Lp(a) and reduce risk of heart attack - but not 100% sure about that)
@@BR-hi6yt Thanks Martin. Yes that might be right if I had/have a problem with inflamation/poor metabolic health and clotting. LDL (oxidized) can be a problem too then. Later knowledge seems to show little to no correlation between LDL and CVD. Better to look at triglyserine/ HDL ratio (mine is perfectly low!) My take on it is that I'm hopefully not getting clots the first time because my metabolic health is very good. I believe the best risk reducing factor is to restore metabolic health if bad, and thus reduce/take away inflammation that I believe causes CVD. After all the body makes different lipoproteins for some reason. This is my point; no inflammation and nothing to heal, then no patching/clots. Lp(a) is not a problem then (as for LDL). I will not take any drug to lover Lp(a) for this reason. I`m perfectly healthy, very fit and will not mess up my body with any drugs. Am I the only man in the world passed 60 with high Lp(a) and perfect blood wessels? Why not put more resources on why is so for me and other oldies like me with high Lp(a)?
@ Gunner Hop I agree, there seems to be something missing here, what about centerians and many others with lpa but no problems, it's just like ldl gets all the talk about lowering it but there's scores of individuals with high ldl for yeas years with no issues, there's a piece missing from this puzzle.. can I ask did your mother or father or relatives have any heart related issues?? You mentioned "gene" lpa?
@@taylorsonstrucking9118 Sorry for no reply until now. I don`t know my parents numbers since they have passed away and I have no access to their blood tests. I don`t think Lp(a) were tested, but they must at least have had the genes. My mother`s twin sister turned hundred years last january, by the way. She has been quite healthy, active and mentally well until last year. 50 years ago I heard from my mother that she was worried about my aunt's high cholesterol levels. Yet she made it to hundred walking on her legs. It seems to me like the whole cholesterol and Lp(a) debate/science are going down the wrong (blind) road.
Is anyone having more then 240 lpa since last 15 year's.
Pharma.....😂😂😂😂