All the students who have qualified either GPAT or GATE are eligible to appear for the NIPER JEE and this number changes every year. If possible I will upload the Cut Off of Last year, right now focus on study, I will upload videos related to NIPER very soon, share the videos with your junior also. thank you
Tomorrow is my son's first birthday, so I m not getting much time, my best wishes are always with you, be confident, victory will be yours. All the best.
You can use that formula also, in this video I have explained the basic way of solving the problem. Short cuts are useful but basic things are essential.
Calculate the percentage of ionized and unionized form of captopril with knowledge that captopril has to pka1 is 3.7 and pka2 is 9.8 . Calculate in blood plasma (ph is 7.4) And in stomach ph(1.9 ) as well as in intestine (ph is 7.4) . Discuss and make comparison between these media and which one is the best for captopril to be used as hypotension drug(estimate bioavailability and permeability of the these forms)? Can you solution this proplem please🌹.
Sir... questions no 8 is some what not uderstanding for me..as per table it's ryt...but see... pH -pka =-1 for weak base..%ionisation would be 90.9%..but antilog of 1=10..then how??? Please once see and tell me sir..
In question no. 8, pH-pKa= -1, that means -1 = log [B]/[BH+] Now take the antilog, Antilog of -1 is 0.1 (not 10 as you have mentioned) 0.1= [B]/[BH+] Which can be written as, 1/10 = [B]/[BH+] Total= ionized + unionized = 10 + 1 = 11 % ionization = Ionized upon / Total = (10/11)x100 = 90.90%
One presentation pH - pKa = 2 , concentration ratio for both acid & base for this value is 100/1 only..if there is -2 then concentration ratio for both acid & base will be 1/100..go through that table..Sorry sir for explaining it in place of you..By the way am I right ?
My dear friend there is slight correction, if pH - pKa = 2, for acid, Ratio of dissociated to undissociated value is 100/1 for base, Ratio of dissociated to undissociated value is 1/100 This happens because for Acids and bases, in Haderson Hasselbalch equation there is change in the ratio of ionized form and unionized form. So, the important things you have check in question are 1) Whether it is asked for Acid or Base and 2) Whether it is asked for Dissociated to undissociated OR undissociated to dissociated.
Sir, i want all problems related to ph and. Ionisation and other , which book should i prefer? And gpat , Niper do they provide logarithms book to calculate log and antilog of some figures? We have to muggup some values? Pls gimme some tips
Зто настолько убедительно..Фантастическое объяснение..deserves millions of views & subscribers..
Спасибо большое, дорогой
Very nicely explained thank u so much sir
Thank you, Sir! This helps me a ton!
sir its very helpful
but i have 1 doubt
how can we know- the given question which equation is used.either weak acid or weak base.. please explain sir
Thank you sir ..very helpful
Sir plz give an que related to juris prudents
Nice sir
Good explanation
Thanks dear, Share it with your friends also. Have a nice day.!!!!
Sir can u please explain this question .
Conjugate acid from of phenylpropanolamine has pka of 9.4 the pecent of ionization of the drugs at ph 7.4 is
Tqs sir u easily explained sir😊
sir can u please tell me how many students attempt in niper exam yearly?
what rank a candidate should get in exam for getting admission in niper?
All the students who have qualified either GPAT or GATE are eligible to appear for the NIPER JEE and this number changes every year. If possible I will upload the Cut Off of Last year, right now focus on study, I will upload videos related to NIPER very soon, share the videos with your junior also. thank you
Tq sir this is so helpful. Sir plz uplaod problems on freezing point depression and elevation in bp before gpat exam plz sir.
Tomorrow is my son's first birthday, so I m not getting much time, my best wishes are always with you, be confident, victory will be yours. All the best.
Sir question no.3 why is not directly put on formula of % ionization = 100/1+(pH-pKa) , ?????????
You can use that formula also, in this video I have explained the basic way of solving the problem. Short cuts are useful but basic things are essential.
Sir why does hendersen equation has Ka instead of Kb for bases?
Sir will you please explain the answer of 6 th question??🙏
Calculate the percentage of ionized and unionized form of captopril with knowledge that captopril has to pka1 is 3.7 and pka2 is 9.8 .
Calculate in blood plasma (ph is 7.4)
And in stomach ph(1.9 ) as well as in intestine (ph is 7.4) .
Discuss and make comparison between these media and which one is the best for captopril to be used as hypotension drug(estimate bioavailability and permeability of the these forms)? Can you solution this proplem please🌹.
ph 5 and morphine pka is 7 then how to calculate pro tonated and unprotonated ratio?
Thanks a lot sir😊
but calculators aren't allowed in GPAT, how are we supposed to take antilog without calculator?
Antilog X = 10x (Antilog of X is equal to to 10 raised to X)
Or simply remember the table and calculate accordingly. All the best
Thank you sir
Tysm sir👍
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Thanks Dear. Best regards.
Question no 4 correct answer is option c 90.9
Sir... questions no 8 is some what not uderstanding for me..as per table it's ryt...but see...
pH -pka =-1 for weak base..%ionisation would be 90.9%..but antilog of 1=10..then how??? Please once see and tell me sir..
In question no. 8, pH-pKa= -1, that means
-1 = log [B]/[BH+]
Now take the antilog, Antilog of -1 is 0.1 (not 10 as you have mentioned)
0.1= [B]/[BH+]
Which can be written as,
1/10 = [B]/[BH+]
Total= ionized + unionized = 10 + 1 = 11
% ionization = Ionized upon / Total = (10/11)x100
= 90.90%
I love you
Sir in Q. 9 if ibuprofen is a base.. Then how it comes 100:1 as it is dissociate : undissociate.. please explain.
One presentation pH - pKa = 2 , concentration ratio for both acid & base for this value is 100/1 only..if there is -2 then concentration ratio for both acid & base will be 1/100..go through that table..Sorry sir for explaining it in place of you..By the way am I right ?
ibuprofen is weak acid..
My dear friend there is slight correction, if pH - pKa = 2,
for acid, Ratio of dissociated to undissociated value is 100/1
for base, Ratio of dissociated to undissociated value is 1/100
This happens because for Acids and bases, in Haderson Hasselbalch equation there is change in the ratio of ionized form and unionized form.
So, the important things you have check in question are
1) Whether it is asked for Acid or Base and
2) Whether it is asked for Dissociated to undissociated OR undissociated to dissociated.
придать смысла , спасибо..
Helpful lecture and nice expkanation sir.... but what to do??? fed up with these frequent adss....... 😥😥
Sorry for the inconvenience, I want to share the knowledge and at the same time it must help to my family, its my one of the source of income.
@@RamPharmaAcademy i admit sir... sorry
Got the basics clear , was much useful , Thanks sir 🙌😀
thnx sir
Good
I didnt understood the last problem plz help
Question no 5 correct answer is option b -3
can you please upload a video based on calculation related to steady state concentration and one compartment model
Tomorrow is my son's first birthday, so I m not getting time, my best wishes are always with you, be confident, victory will be yours. All the best.
thank you sir and congratulations to you
Question no 3 correct answer is 0.99
This video mistake is ph-pka is not correct pka-ph is correct
Dear friends don't study is video whole video is wrong,correct ionisation table in book coop and guns 12th Edition page no 259
Sir, i want all problems related to ph and. Ionisation and other , which book should i prefer?
And gpat , Niper do they provide logarithms book to calculate log and antilog of some figures? We have to muggup some values?
Pls gimme some tips