6. Nucleic Acids
ฝัง
- เผยแพร่เมื่อ 11 พ.ค. 2020
- MIT 7.016 Introductory Biology, Fall 2018
Instructor: Barbara Imperiali
View the complete course: ocw.mit.edu/7-016F18
TH-cam Playlist: • MIT 7.016 Introductory...
In this final lecutre of the Biochemistry unit, Professor Imperiali covers nucleotides and nucleic acids, discussing their structures and their importance as fundamental units for information storage and information transfer.
License: Creative Commons BY-NC-SA
More information at ocw.mit.edu/terms
More courses at ocw.mit.edu
![ความรักไม่ได้น่ากลัวขนาดนั้น (TRUST ME) - LYKN [ OFFICIAL MV ]](http://i.ytimg.com/vi/9np-lAtCRpQ/mqdefault.jpg)
She’s the best. It’s no easy task to wrest clarity from a complex reality, but she does it here. More Imperiali videos, please!
what, in your opinion, makes her the best. Then you have had very poor lecturers. Her progression does not facilitate a beginner.
(On Sunday of January 29, 2023). In the Matter of Biochemistry of MIT Introductory Course of Biology; By PhD Barbara Imperiali; 1) Nucleic Acid in the Various Possible Molecular Structures (1 Encoding Information Function; 2) Energy Transfer (ATP); 3) Protein Biosynthesis (in the Functional Isomeric Form of RNA); Chemical Structure Therein in: 1) Purine (A Double Aromatic Ring Nucleobase); 2) Pyrimidine (A Heterochromic Ring Molecule); 3) Nucleobase Pairing (Adenine, Guanine [Purines]; Cytosine Thymidine [Pyrimidine]), A, Deoxyribose Monosaccharide (Pentose Sugar); And the Phosphate Backbone is the Primary (Non-Covalent Bonding; Hydrogen Bonds, Glycosidic Bones and Phosphodiester Bonding) Nucleotide Formation Chemistry; RNA Chemical Configuration Nevertheless Follows the Most Stabilizing Purine-Pyrimidine Complementarity Principle with The Exception Uridine Replaces Thymidine in RNA Synthesis Processes (mRNA, tRNA, rRNA [Ribosomal Related] and many other Formations; Conserved and Evolutionary Significance: 1) Perhaps only Covalently Bonded Carbohydrates are the only oldest precursors in Biochemical Molecules while Nucleic Acids are known to Travel through the Universe in Comets and Other Celestial Momenta (RNA theorized herein as The Oldest of Nucleic Acid); 2) Most Significant Biomolecule in Biological Evolution (Inheritance [Memory in Chemical Form] and Energy Biosynthesis; PhD Barbara Imperiali, es sehr gut zu wiederlernen und tiefich denken Mit ihnen uber Biochemie. Heil!
I don't know the name of the Professor but she is simply outstanding both in her teaching method and energy and I am sure she will be the favorite of all students
Barbara Imperiali, it's in the video description
Hats off to your efforts Madam! Great energy and outstanding teaching! Supreme command of the subject!
You're the best.
Watched from Zambia 🇿🇲🇿🇲
Well simplified. Amazing work Prof. ❤
Important note:
1. Why is DNA anti parallel (5'-3'), why not the opposite?
Ans: Because of thermodynamics Stability & Good H bond
2. Which strand is more stable?
Ans: Strand that has max (G triple bond C) and max H bond.
3. Other than H bond what are the other forces that contribute on making a DNA structure stable?
Ans: Hydrophobic forces at each step can make a stable DNA structure ; proven by research.
The A-T double bond is more favored than the G-C given the triple bond is much harder to break correct?
Thank u MIT, you upload this awsome learning video, the lecture is so active and i very amazed with her teaching.
I didn't know that there is professors like her are existed 🥺
Omg thank you so much ❤
Absolutely well done and definitely keep it up!!! 👍👍👍👍👍
I want actually thanks to this channel for providing such a great lacture . This lacture is really very help full for understanding
Great professor.Listing 2nd time.very useful.
These lectures are fantastic! A review for me but very well presented. Your students are lucky.
Thank you Ma'am! This was an interesting lecture.
Hi Madam! I am a great fan of your lectures! I love your accent and presentation skills! Thank you!
watching this makes my previous lessons on biology/biochemistry make SO MUCH more sense. my professor skipped a lot of steps/explanation so it was more memorization than logic, kind of frustrating :( but this is great! thanks!
Amazing presentation! THX!!!
THIS IS AMAZING THANKS SO MUCH, I LOVE THE ENTHUSIASM U PUT i wish my teachers were as good as you!
Excellent platform of professors
Excellent lecturer!
Been looking all over youtube for one part that's better here than anywhere else: How do base-pair H bonds arise? Thank you!
Amazing learning experience!
Thank you Ma'am!
Really inspired and "affected" by her energy.
amazing presentation madam!
Can someone explain to me the part of the complementary strand q
I couldn't understand how the prof answered it
She’s amazing
I'm grateful
thank you
Thank you
PROFESSOR Barbara Imperiali , what is the evolutionary advantage of thymine replaced by uracil in RNA molecule ? although they both have small structural change in functional group ?
has far has my knowledge goes the presence of thymine gives additional stability to DNA
神仙老师！！！
I've started to watch this playlist but I don't know what exactly this is; can someone please explain what part these whole lectures are of? Is it university beginning or something, maybe even repititions from what you learn in school? (At least here in Germany if you have physics and chemics you don't have biology from year 10-12) so I'm wondering. Still whatever is is it may be a little help for my future (hopefully I can start studying biology soon)
47:00
Looks like they had fun "playing" 🤔, maybe that compensates the boring parts of work if they had some 🤔
This course is MIT 7.016 Introductory Biology as taught in the Fall 2018. View the complete course materials at: ocw.mit.edu/7-016F18. This material is normally covered during the beginning of the undergraduate cycle.
@@mitocw Thanks!
Amazing!!
Make sense!
Might one of the purposes of non-coding DNA be simply the stability of the molecule? Obviously there's much more to it than that. But if DNA sequences are unstable if they are too short... then it might make sense to pad them. Could be completely off track here, of course.
Thank you mam.wonderful.
😢ki mm.
Thanks
Thanks so much for the lecture producer. Part of the knowledge has solved a perennial problem of mine, but please allow me to give an advice to the Photographer, would u please keep the len stable? The fast rotating picture dizzied me and I belive there is someone also has the same feeling with me.
Can u give me the notes of this topic
Not really, if you're really invested in her fantastic presentation you don't even notice the lens. I'm just really enjoying the information shes sharing with so much Clarity including her very clear notes on the board and slides
Wow, I really wish my crappy professors explained like this.
@17:26 - I guess if it's [S]tandalone (or [S]impler), it's a nucleoSide. But if it's [T]ied to phosphate(s), it's a nucleoTide.
😀
That ancient welsh Lord of the Rings fairy writing when she wrote 'Chargaff' was pretty nice.
Thanks mam 🤓 love from India
I like it
Writing the dna pair upside down I may use that for intro biochem if the prof asks that on a test
Nature is 🤔 interesting. Dang!!! This woman is smart and knowledgeable!!! This is just the Basics too. 😲😲😲😲 All of the Implications!!!!
31:30
Wish she is my teacher. 😊
use DNA for programing? ok, MIT creates a god just a matter of time.
How cell make nucleic acids? Or they came magically.no one explain this.
🌺🌺💖
Is the bottom of her hair purple or is it just my screen?
I had the same thought, and I think it's not, just an effect of the bright light reflecting off her shirt at some angles. Although it would be super cool for a professor to have coloured hair. even a streak or an ombre. shows some personality lol
You exagerate the importance of Franklin. It is now that you make an interpretation of the distances. At that time nobody saw it. It is by playing with card board that all became clear.
While I appreciate her knowledge, she makes little effort to impart intuitive knowledge. She is always in a rush to move on, whether she knows she made hour block become 45 mins is debatable .
Overall a pass
Pls I am a high school level life science instructor. What do you mean by imparting intuitive knowledge. I am asking for the benefit of my students just in case it is something I have been overlooking too. Thanks and eagerly awaiting your kind response.
Indian is best
No