Diabetes Mellitus | Clinical Medicine

Exclusive USMLE Step 2/PANCE Lecture… for FREE! Become a member on our website for more Premium Resources: ninjanerd.org/lectures/diabet...
Ninja Nerds!
In this lecture, Professor Zach Murphy will present on Diabetes Mellitus. We will discuss the pathophysiology, differentiating between Type 1 diabetes, characterized by autoimmune destruction of insulin-producing beta cells in the pancreas, and Type 2 diabetes, resulting from insulin resistance and relative insulin deficiency. The lecture will include a discussion on the clinical manifestations, such as polyuria, polydipsia, and unexplained weight loss. The digital presentation will begin with the diagnostic approach, highlighting the importance of fasting plasma glucose levels, the oral glucose tolerance test, and glycated hemoglobin (HbA1c) measurements. Finally, we will review management strategies for Diabetes Mellitus, emphasizing the role of dietary management, physical activity, blood glucose monitoring, insulin therapy for Type 1 diabetes, and oral hypoglycemic agents for Type 2 diabetes. Enjoy the lecture and support us below!
Table of Contents:
0:00 Lab
0:07 Diabetes Mellitus Introduction
0:18 Pathophysiology of Diabetes Mellitus
8:56 Complications/Issues with Diabetes Mellitus
21:40 Diagnostic Approach to Diabetes Mellitus
25:21 Treatment of Type I Diabetes Mellitus
30:07 Treatment of Type II Diabetes Mellitus
35:23 Treatment of Diabetes Mellitus Complications
44:35 Comment, Like, SUBSCRIBE!
Retired Ninja Nerd Lectures:
• Diabetes Mellitus | Ty...
• Diabetes Mellitus | Ty...
• Diabetic Ketoacidosis ...
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#ninjanerd #endocrine #diabetesmellitus

[@mark46]

That's millions of times better than the board; the information is more organized here, and you're more at ease. Still, we have no complaints, as it's free.

[@dm9392]

Pleaae bring back the white board!

[@hehehhe5461]

this is soo good, described everything from pathology to how it impacts everyday clinical scenarios. thank you a bunch

[@idontspeekgeek72]

Hey! i would love to see a DKA vs HHS video please! I am studying for my PCCN. i love watching your videos because i can actually understand the "why" behind things. thanks for all your time put into these videos!

[@michelleguthery6514]

I absolutely love your videos. You aid me in actually understanding the foundation to things.

[@rumaisashahid]

Thanks a lot for breaking it into digestible chunks!!

[@ayezawaseem3634]

Thankyou for these! You surely are a life saver. I love how easily these summary charts in your videos help me correlate it to a real life patient

[@sanjith1179]

I'm pratheesh from India (Tamil Nadu).big fan of you sir.say one hii sir..

[@ok6109]

Why are you every where bro ?😂

[@omoooooo4275]

Look what I found! A fresh video! Thank you for your efforts!

[@b.a.m3165]

Zach if u don’t mind …
I want to enter your brain to see how he made any topic easy & digestible to be understood
Thanks 👏🏻

[@jamesm3671]

This clinical medicine lectures are Awesome,keep them coming,,Thank you

[@marwaelg6323]

This really came at the right time ! Thank youuuu

[@queteimporta7049]

This is an awesome video. Very helpful and understandable. I just want to say that I prefer the board videos where you explain more detailly. But you are the best ❤

[@sarahsandy2204]

Honestly AMAZING!! LOVING this new series - thank you so so much :))

[@Kittyslay-ox4tk]

Thanks. The content and your clear presenting skills are brilliant. Also appreciate the modern, digital diagrams. Much more easier to absorb the complex info.

[@ShowBoySagar]

Thanks for uploading 3 dyas before my exam

[@valviv]

Great video, thanks Ninja Nerd!

[@vincentcyrilliansantoso9858]

ZACH, please make more of the "study case" playlist!
IT'S UNDERSTANDABLE AND MAKE SENSE A LOT!
i'm looking forward to see more of the playlist!
Keep it up, God bless you!

[@consideration8881]

Oh just realized Zach renewed the diabetes video. That's cool!

[@DeVergam]

Make a playlist with all the clinical videos please

[@surfergirl22330]

The best always! Thank you!

[@nasiruddinnabil8922]

Can anyone please give me pdf of this class!?

[@mariamaboutouk8849]

Thank youuu🎉 I like the clinical med videos so much

[@user-nq7ie8od4f]

Thank you so much

[@clementmasai7487]

Where is the dka vs hhs video? Once watched but not seeing it anymore

[@charmondkingren2105]

Very helpful. Thank you

[@hala._bee]

Thankyou sir❤
New method is superb ❤

[@gabrielasion]

Thank you very much!

[@sumaya2690]

Im from kurdistan and i want to say thank you sooo much for your detail information ,Im in dental collage 🦷 and needed your information to understand .✨✨🙌🏼

[@shahiramohammadi7284]

Like always great

[@caitlynkay5066]

This is a great video! Please consider doing a DKA and HHNS video! This would be extremely helpful as a new endocrine APN

[@love2shop1996]

Will there be notes posted soon for this?

[@mawunyokukah6611]

Great work ❤

[@singletrak1]

In DKA even if the AG is closed don't you want to continue the ins gtt until the BG's are stable for 24hrs or ar least 3 BG's

[@XayatiAbdifatah]

thanks ninja 😊

[@vLion]

Thanks

[@user-dm6ib6kc7h]

Look who comes back💥💥❤

[@Anarchers]

I love the squeaky whiteboard pens! :)

[@j0425]

I can't see clinical medicine playlist? Sir

[@olyashepova5988]

Thanks!

[@Mac61202]

What about later stages of T2 diabetes where insulin production by the body is greatly decreased (or completely gone) and insensitivity is increased. For instance, what if someone came to the ER due to dizzy spells and an inability to walk short distances without fainting but previous to that hadent seen a doctor for over a decade. Would their T2 diabetes have progressed far enough to warrant lipolysis and ketone bodies in the blood since glucose wouldent be a viable source of energy anymore. Would we then see symptoms of DKA in T2 diabetics similarly to T1 diabetics? My thought process is that there would be protein and glucose loss through glomerular damage which would pull water from the system. Patient becomes dehydrated and begins exhibiting orthostatic tachycardia and only visits the ER when the issues become prevalent enough.

[@deborahopabola7202]

God bless you

[@MudasirKhan-cb3fp]

thanks

[@grumpyinbrooklyn6347]

You should add other types of diabetes in the future, particularly MODY and 3c. I suspect MODY is grossly underdiagnosed and thrown into the T2D or T1D types way too much!

[@aryasree8471]

Great ❤...

[@mfonufot1328]

The fonts on the presentation are so tiny and not clear, I prefer the white board

[@wangari.t]

Also the levels of sorbitol increase due to a dysfunction of the enzyme SORBITOL DEHYDROGENASE, which converts sorbitol to fructose.

[@allthingsecho]

Please revert back to the original whiteboard Easy to get bored with thus this format.

[@ronaldnthwana476]

Yes please

[@jennykimat1954]

I agree

[@user-mg1qp5jk7x]

PLEASE 🙏

[@naveedkhannk2325]

Pls sir

[@samphonnetgamgee5625]

No! This format is clearer, only that it should be larger, as we don't see anything.

[@vastv2024]

Legend

[@swadud1937]

7:57 - Why can glucose not be utilised in diabetes? Surely the high glucose content in the blood doesnt require insulin to enter cells via facilitated diffusion using GLUT1 receptors? What is meant here by not being able to utilise carbohydrates?

[@francescopaolofabozzi1592]

I think that GLUT1 alone cannot provide enough glucose for some tissues to use, for example muscular tissue. That's why insulin reduction determines metabolic switch to lipolysis.

[@craciunandrei9755]

Because the insuline resistance , the receptor cannot be acctivated properly and GLUT molecules cannot go into the membrane

[@mertgundogdu211]

YOOU ARE LİFE SAVIOR

[@khayrkafaafi8779]

Please let’s reverse back to the use of our white board learning module this would give us the real classroom room learning experience, something that really marked different than any other learning platforms( if so less) 😢 .

[@nancyrajyaguru]

Sir,You didn't include 1.5KPD and 1.5 LADA

[@rafikijustin7903]

Love

[@subayyalkhan5814]

Sir this method isn’t working like your previous method on white board sir please revert back to whiteboard plzzzzzzzzzz

[@ahmedluay5366]

Where is Old DKA video 👀💔

[@abhaysudhi7485]

How many views does it have now?

[@abhaysudhi7485]

1.2k

[@nakkarahul6118]

12k

[@jewelsaju5168]

❤❤

[@MudasirKhan-cb3fp]

love u

[@sumedhahaha]

8:51

[@MEDICO5912]

❤❤❤❤

[@user-ti8uo9ku5i]

I am Ayushi from India

[@ece4038]

Süper

[@elina4ka47]

thats cool but ... we want the board back :(( #oldschool

[@user-zz9iw5ti2b]

White board was better brother!

[@shammshtiwe8159]

Please pleeeaassseeee revert ti the whiteboard that is what make ur identity 🥺🥺🥺🥺🥺💔💔

[@ShemMwangi-no8nz]

Please turn to whiteboard,this format is boring

[@charmondkingren2105]

Please be appreciative for the time, effort and costs of a thoughtful and generous teaching presentation.

[@nutansharma4369]

Chalk and talk is better not this

[@drzz2]

Best ninja 🥷

[@saxgirlhornboy6458]

A1c must be > 6.5 to establish diabetes? 🤔
How many eyes, feet, kidneys, etc., would be put at risk by this high bar?

[@saraQasim-dn2vh]

marry me🥹🤎

[@iHATEbigots666]

it can take wayyyy to long to find out you have type 1 diabetes