Thank you. At 1:25 , the small round dark nuclei...aren't they small lymphocytes? they look smaller than the other lymphos in the background...can the follicular epithelial cells have such small nuclei esp when you compare with the size of the Hurthle cell nuclei? and why would the follic epithelial cells appear as bare nuclei ? Similar looking small and dark nuclei at 6:11 are part of a spectrum of a polymorphic populaton of lymphoid cells..Thanks in advance.
Hi, it is not uncommon to see bare thyroid follicular nuclei, as the cytoplasm can be quite delicate. Look for them in your FNAs! The size of non-Hurthle cell nuclei is smaller than that of Hurthle cell nuclei. Hence the very round nuclei that are bare are likely to be follicular cell nuclei, while lymphocyte nuclei are slightly more irregular and usually (though not always) retain a thin rim of cytoplasm. I hope this helps!
Excellent mam, it helped me a lot!🌹
Thank you. At 1:25 , the small round dark nuclei...aren't they small lymphocytes? they look smaller than the other lymphos in the background...can the follicular epithelial cells have such small nuclei esp when you compare with the size of the Hurthle cell nuclei? and why would the follic epithelial cells appear as bare nuclei ? Similar looking small and dark nuclei at 6:11 are part of a spectrum of a polymorphic populaton of lymphoid cells..Thanks in advance.
Hi, it is not uncommon to see bare thyroid follicular nuclei, as the cytoplasm can be quite delicate. Look for them in your FNAs! The size of non-Hurthle cell nuclei is smaller than that of Hurthle cell nuclei. Hence the very round nuclei that are bare are likely to be follicular cell nuclei, while lymphocyte nuclei are slightly more irregular and usually (though not always) retain a thin rim of cytoplasm. I hope this helps!
Thank you for your teaching mam..
Nice thank you