Wolff - Kishner reduction / reaction of ketones and aldehydes | Complete mechanism with examples
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- เผยแพร่เมื่อ 12 ต.ค. 2024
- In this video complete mechanism of Wolff - Kishner reduction or Wolff - Kishner reaction is given. It proceeds via the formation of hydrazone or semicarbazone and liberation of nitrogen gas. Carbnion formation also takes place during the reaction. Sodium hydroxide or potassium hydroxide or sodium ethoxide or potassium ethoxide is taken as the base in high temperature. It is basically a deoxygenation reaction.
Books consulted:
1. Reductions in organic chemistry by Milos Hudlicky
2. Modern Methods of Organic Synthesis by W. Carruthers
3. Organic Chemistry by Jonathan Clayden, Nick Greeves, Stuart Warren
Thanks u so much, Great help
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