Immunology | Immune System: Overview

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  • เผยแพร่เมื่อ 30 มี.ค. 2017
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    Join Professor Zach Murphy for our overview lecture on the immune system. This lecture will include a summarized and high-yield explanation on the inflammatory process and adaptive immunity. We hope you enjoy this lecture and be sure to support us below!
    Inflammatory Response Video Series:
    Part 1: • Immunology | Inflammat...
    Part 2: • Immunology | Inflammat...
    Part 3: • Immunology | Inflammat...
    Part 4: • Immunology | Inflammat...
    References:
    ● Microbe Online MHC1 and 2 [Digital photo]. microbeonline.com/difference-...
    ● Lumen Microbiology Course [Digital image] courses.lumenlearning.com/mic...
    ● Soman N Abraham. ResearchGate [digital image] Retrieved from: www.researchgate.net/figure/L... 2011
    ● Microbe Notes. MHC function [Digital photo]. microbenotes.com/major-histoc...
    ● Bio LibreTexts. Types of chemicals signaling [Digital photo] bio.libretexts.org/Bookshelve...
    ● Assay Genie. Cytokines [Digital photo] www.assaygenie.com/cytokines-...
    ● Aun.edu. MCQ Quiz on Immunology [Quiz] www.aun.edu.eg/SECI/questions/...
    ● MCQ on Cytokines, Interferons & Interleukins 2021.c [Quiz] www.medicalbiochemist.com/201... Immunology:
    ● Oxfor University Press. 2016 Playfair & Bancroft: Infection and Immunity 4e [Quiz] global.oup.com/uk/orc/bioscie...
    ● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
    ● Marieb EN, Hoehn K. Anatomy & Physiology. Hoboken, NJ: Pearson; 2020.
    ● Boron WF, Boulpaep EL. Medical Physiology.; 2017.
    ● Urry LA, Cain ML, Wasserman SA, Minorsky PV, Orr RB, Campbell NA. Campbell Biology. New York, NY: Pearson; 2020.
    ● Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine. New York etc.: McGraw-Hill Education; 2018.
    ● lberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. New York, NY: Garland Science; 2002
    ● Murphy K, Weaver C. Janeway's Immunobiology. Garland Science; 2016
    ● Doan T, Melvold R, Viselli S, Waltenbaugh C. Immunology. Lippincott Williams & Wilkins; 2012
    ● Levinson W. Review of Medical Microbiology and Immunology. Lange; 2012
    Adaptive Immunity Lecture:
    • Immunology | Adaptive ...
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    #ninjanerd #ImmuneSystemOverview #Immunology

ความคิดเห็น • 204

  • @laluna5548
    @laluna5548 4 ปีที่แล้ว +866

    Is there a Nobel prize for teaching ? I have been watching your channel for over 2 years now. Cannot thank you enough!

    • @andreainzaghi7373
      @andreainzaghi7373 3 ปีที่แล้ว +8

      best biochiemistry teacher is this one, best math teacher is the italian professor Maurizio Schirinzi of EasyMath

    • @tapiwa8549
      @tapiwa8549 3 ปีที่แล้ว +3

      well said

    • @mrsamandabernier
      @mrsamandabernier 3 ปีที่แล้ว

      @@andreainzaghi7373 good to know!

    • @sujeetkumarmauryamscisemes9319
      @sujeetkumarmauryamscisemes9319 3 ปีที่แล้ว

      @@andreainzaghi7373 sir can you please suggest any BOTANY MASTER DEGREE TH-cam channel

    • @perio-implantadvisor1314
      @perio-implantadvisor1314 3 ปีที่แล้ว +1

      well said

  • @gimee0352
    @gimee0352 5 ปีที่แล้ว +277

    Today I passed my immunology exam after many tries, can't thank you enough for your immunology series, it allowed me to understand immunology as a whole, because ALL the topics are intrinsically related here, and I think it's something that doesn't occur in other disciplines where the topics are more independent (not sure if it makes sense for somebody else or it's just me xD) Thanks for making good quality videos, I'm sure it takes a lot of time but it's so much worth it. Thanks again, I really mean it, and keep up the good work, you're awesome.

  • @alissabarcelona479
    @alissabarcelona479 3 ปีที่แล้ว +82

    You are helping shape many awesome doctors out of this bunch of Ninja Nerds!!! You are exponentially saving sooooo many lives!!!! The world owes you BIG BIG THANK YOUUUUUs!!!

  • @connorestes9814
    @connorestes9814 2 ปีที่แล้ว +45

    I genuinely think that almost solely studying with all of the videos by Ninja Nerd could almost get you through med school. Of course, there is more stuff like certain types of physical examination, internships etc. that one has to learn/go through, but for the theoretical part of med school I’ve almost only studied with your guys‘ videos and passed every single exam (with really good grades, on a side note). Y‘all should genuinely just establish your own med school one day where Professors etc. are trained to teach like you, I‘m 100% sure you‘d have some of the highest graduation and overall passing rates on exams etc. 😂❤️
    I just can‘t thank you enough for the work you all put in to these videos and this channel, you are helping SO MANY people so unbelievably much. You guys are without a single doubt real heroes. Y‘all don’t get anywhere near enough recognition for the so important work that you do. Thank you, really, from the bottom of my heart. You‘re the best ❤️

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  2 ปีที่แล้ว +28

      Thanks so much for this incredibly thoughtful comment! Ninja Nerd University - We like the sound of that… 😎

  • @jenniferdugan581
    @jenniferdugan581 4 ปีที่แล้ว +20

    You're the only reason I've been able to digest the physiology content in my PT program, I would be wildly confused without your awesome videos. Thank you so much for your amazing teaching!

  • @silviagc6070
    @silviagc6070 4 ปีที่แล้ว +11

    You are absolutely AWESOME! I've been watching your videos for almost 3 years and I needed to thank you. Great job all the team. And you, Zach are the best teacher!

  • @pedrobastos2721
    @pedrobastos2721 2 ปีที่แล้ว +7

    I rarely comment on videos, but had to come back here to thank you deeply for your Immunology classes.
    I was barely able to attend any classes during last semester because of COVID complications and I was freaking out the night before my Immunology exam not knowing anything at all.
    Thanks to you I managed to pass. Thank you so much. Amazing videos.

  • @fredred476
    @fredred476 3 ปีที่แล้ว +10

    thanks for taking time to do the summary vid(s). they are really helpful at bringing complex topics together. another great set of lectures.

  • @hansini99
    @hansini99 3 ปีที่แล้ว +22

    We all can't thank you enough. I feel so much more confident for my med school exam tomorrow thanks to your videos.

  • @debbiedebsel
    @debbiedebsel หลายเดือนก่อน +1

    You are an amaziiiiing teacher!! Thank you so much for making these videos. You are truly talented !!!!
    I didn’t understand immunology at all at first just from the uni lessons, but these few videos made it so clear, THANK YOU!

  • @jmmanuelseale1203
    @jmmanuelseale1203 5 ปีที่แล้ว +22

    dude.....listen man...you blew my mind with vast knowledge you have mastered...keep up the great work and studies....you are truly a master

  • @christophermartinez6479
    @christophermartinez6479 4 ปีที่แล้ว +5

    Thank you!!! For all your videos (the rest of the team too, not sure who else works on these but you're also appreciated!)

  • @someone.F.e
    @someone.F.e 3 ปีที่แล้ว +8

    You made it in less than 20 minutes!!!!!!! Well done!!!!!! Make sure to get the prize!!!

  • @KCMDWannabe
    @KCMDWannabe 4 ปีที่แล้ว +4

    Incredible job with this video. Seriously amazing that you're able to provide all of this. It must help with reconciling your knowledge of the topics hey?

  • @bethanytowne2970
    @bethanytowne2970 5 ปีที่แล้ว +38

    dude. this is such an incredible video!

  • @phoenixmidekings9333
    @phoenixmidekings9333 8 หลายเดือนก่อน

    Over and over the best in the field so far, you're a well seasoned tutor

  • @palaksharma8025
    @palaksharma8025 3 ปีที่แล้ว +17

    Iam surviving in medical school ..... just because of this great man!! 🤴🏻 THE KINGG!! ❤️

  • @sarahabling3842
    @sarahabling3842 4 ปีที่แล้ว +18

    Intelligence attracts 😍that’s what happened to me ... thank you for making my ongoing pg preparations easy ...love from india 🇮🇳

  • @allykeathley
    @allykeathley 5 ปีที่แล้ว +1

    Absolutely love these videos. Thank you SO much.

  • @The_hustletown_PA-C
    @The_hustletown_PA-C 4 ปีที่แล้ว +4

    I was like dang this guy is either a damn good doctor or scientist....your intro video at PCOM
    popped up on my TH-cam to watch feed and I found out that your a fellow PA which makes me love your videos even more

  • @tangogog
    @tangogog 3 ปีที่แล้ว +6

    You guys are the masters of teaching! So sorry to find you so late :( Thank you for this beautiful lecture...

  • @yachiapatel
    @yachiapatel ปีที่แล้ว

    Can't be more of thankful to this guy for giving such detailed knowledge about immunology ❤❤❤

  • @silk.spectre6606
    @silk.spectre6606 5 ปีที่แล้ว +13

    Something I couldn't put together for days, you put into a beautiful story that now makes perfect sense! Thank you for your videos! Thanks to you I get straight As in all my exams! Keep doing it, please!

  • @asmamajeed7551
    @asmamajeed7551 5 ปีที่แล้ว +2

    Fastest way to cover whole immunology good work keep it up

  • @mussangolo8169
    @mussangolo8169 4 ปีที่แล้ว +4

    Men your incredible!!, God bless you these lectures helps me a lot

  • @AssafLavie
    @AssafLavie 3 ปีที่แล้ว +16

    I'm just here waiting patiently for the episode where he reviews all those back tattoos. Maybe season finale?

  • @siaali4057
    @siaali4057 2 ปีที่แล้ว

    How can someone be so good at teaching man. Please keep up the good work you're doing. 😭♥️♥️♥️

  • @bonvoyage3076
    @bonvoyage3076 5 ปีที่แล้ว +3

    Awesome. Good overview, need this for each subject.

  • @aparnavenugopalan6108
    @aparnavenugopalan6108 2 ปีที่แล้ว

    thank you for making the concepts crystal clear for me...

  • @tariqhassan7306
    @tariqhassan7306 3 ปีที่แล้ว

    I am made at myself why you are not hitting it to million subscribers!!
    No body can match your potential....!!
    Thank you sir,lot of love and respect for you...

  • @rwaidaalkhoury5885
    @rwaidaalkhoury5885 3 หลายเดือนก่อน

    TBH this immunology series cures depression, you describe the entire process with such enthusiasm and love to the matter that it made me appreciate how my very human body fights every second to protect itself :')

  • @rebeccarebecca8880
    @rebeccarebecca8880 8 หลายเดือนก่อน

    Your teaching style and explanations are amazing!! You get the point across with every video. You should make a video on how you prep and teach. Then you'd have mini-professor Zachs-- worldwide.

  • @tarekbarek4407
    @tarekbarek4407 3 ปีที่แล้ว +5

    I love your videos! Can you please make a video about the four types of hypersensitivity?

  • @popotrou
    @popotrou 2 ปีที่แล้ว

    Thank you very much! This is extremely helpful. A great summary

  • @wolfie5470
    @wolfie5470 4 ปีที่แล้ว +1

    Hope the prize was great!
    I've written it many many times but I will do it again - you are THE BEST ♕
    Thank you so much

  • @pluto4479
    @pluto4479 3 ปีที่แล้ว +1

    Thank you so much. Please complete the series please

  • @sirinesaleh5398
    @sirinesaleh5398 3 ปีที่แล้ว

    Hello ninja nerd, first thank you so much for your videos they saved my life.
    Can you make more immunology videos, because a vast subject, and i think many people, other than me need them ( cytokines and chemokines, Dendritic cells, MHC, B-cells development, immunological synapse).
    Thank you deserve so much more recognition.

  • @user-gd1qw2wc1j
    @user-gd1qw2wc1j 4 ปีที่แล้ว

    Very good video for reviewing all the things of inflammatory, Thanks a lot from Thailand

  • @Tiemsuplo
    @Tiemsuplo 2 ปีที่แล้ว

    He is a hero for my medical school journey

  • @charmmorningstar7530
    @charmmorningstar7530 11 หลายเดือนก่อน

    u saved me from passing all my bio classes. thank you❤❤❤

  • @nosotress4744
    @nosotress4744 6 ปีที่แล้ว +3

    Great Job- You win!

  • @wedabdullah3404
    @wedabdullah3404 ปีที่แล้ว +1

    Thankyou Doctor your vedioes helped me so much Im really preciatied.⚘⚘

  • @halisai5347
    @halisai5347 4 ปีที่แล้ว +1

    Fantastic lectures, excellent job dude~

  • @duhancigil8302
    @duhancigil8302 2 ปีที่แล้ว

    It was very helpful for me to understand this subject. Thank you

  • @phoebele7585
    @phoebele7585 ปีที่แล้ว

    Thanks for great videos! Would love a systemic lupus erythematosus review, please!

  • @tizitageleta1765
    @tizitageleta1765 4 หลายเดือนก่อน

    i appreciate your teaching style. and i think its better if your videos have subtitles.

  • @BirhaGebre
    @BirhaGebre 4 หลายเดือนก่อน

    Ninja...Thank you very much your way of teaching is interesting

  • @SFLARay
    @SFLARay 3 ปีที่แล้ว

    brilliant pedagogy!

  • @109nazrananazwali6
    @109nazrananazwali6 2 ปีที่แล้ว

    Your are the bestest teacher of the world...
    Stay blessed 💖

  • @anumtassadaq
    @anumtassadaq 3 ปีที่แล้ว +2

    thank you, i appreciate your effort

  • @aayushraj5654
    @aayushraj5654 2 ปีที่แล้ว

    Man u are a savoir for me becoz of u only I was able to write all the exams paper so smoothly and that to before a day of studying 😅 thanks a lot ❤

  • @muhammaddewanggaputralaksa7850
    @muhammaddewanggaputralaksa7850 3 ปีที่แล้ว

    thanks for zach and team, i love you guys

  • @brunaiglesias5542
    @brunaiglesias5542 7 หลายเดือนก่อน

    This has helped me so much! Thank you!!

  • @labrat7855
    @labrat7855 3 ปีที่แล้ว

    Here iam again 🖐😂 watching my review... whenever i have a school lecture reporting, i always come to you.. it helped me alot.. thanks... keep going bro! Godbless

  • @benkim2517
    @benkim2517 3 หลายเดือนก่อน

    Always love your detailed lecture videos! One thing I haven’t been able to fully understand…
    How do RBCs (anucleated) able to avoid aptosis by NK cells since they lack MHC I molecules?

  • @fatiahanda3613
    @fatiahanda3613 ปีที่แล้ว

    Ninja Nerd.. your videos are amazing and helpful.

  • @user-im1my5nh2x
    @user-im1my5nh2x 2 ปีที่แล้ว

    Its just like all all all in an only14 minuets
    that's amazing !

  • @kamyarshahsavani8596
    @kamyarshahsavani8596 2 ปีที่แล้ว

    Master of summarizing. 😁

  • @camilasousa5853
    @camilasousa5853 2 ปีที่แล้ว

    This is the best class everrrr!! Thank youThank youu thank youuuu

  • @sreemahalakshmilakshminara183
    @sreemahalakshmilakshminara183 7 หลายเดือนก่อน

    Thank you very much for your lectures sir. It is very helpful

  • @user-vk4dn1ku7o
    @user-vk4dn1ku7o 3 ปีที่แล้ว

    beautifully explained

  • @amyyypikaa
    @amyyypikaa 5 ปีที่แล้ว +5

    Just want to let you know, your the reason my semester at my med school has passing our classes :D

  • @danielva422
    @danielva422 2 ปีที่แล้ว

    I could not pass my test without your explanation. Tnx

  • @alsy1681
    @alsy1681 2 ปีที่แล้ว

    Give this man our tuition

  • @princetandukar9290
    @princetandukar9290 2 ปีที่แล้ว

    Good way to remember the inflammatory mediator chemicals are during this damage "HELP" is releases (Histamine, LEukatrine and Prostaglandins)

  • @alsy1681
    @alsy1681 2 ปีที่แล้ว

    Please give this man a Nobel prize

  • @nayelimeza6768
    @nayelimeza6768 3 หลายเดือนก่อน

    you are the reason why i get A's on all my anatomy exams

  • @marytembe4288
    @marytembe4288 4 ปีที่แล้ว

    Thank you sir!

  • @aribahbhatti8678
    @aribahbhatti8678 2 ปีที่แล้ว +1

    the effort that u put in these videos is just amazing. Thank u so much for teaching soooo good and making my life much more easier

  • @faribaabbasyoun1618
    @faribaabbasyoun1618 3 ปีที่แล้ว +1

    Amazing lecture 👌🏻👌🏻

  • @milenad.2645
    @milenad.2645 ปีที่แล้ว

    Thank you so much!

  • @diariodasofia
    @diariodasofia 2 ปีที่แล้ว

    So good as always, thank u

  • @aimsilaon7644
    @aimsilaon7644 4 ปีที่แล้ว

    This is literally the best

    • @aimsilaon7644
      @aimsilaon7644 4 ปีที่แล้ว

      Perfect amount of details

  • @phoenixkats
    @phoenixkats 3 ปีที่แล้ว +7

    Quicksilver : I am the fastest man alive
    Flash : Oh really? You don't run fast enough to leave light behind, do you ?
    Meanwhile Zack ( Immunology in 14 minutes stat) : Bring my marker! These noobs need some lessons!!

  • @madalinacebuc3844
    @madalinacebuc3844 5 ปีที่แล้ว +8

    May I ask a question:
    You said the MHC1 is present on all nucleated cells, as the erythrocytes aren't nucleated, how come the NKcells do not target them or did I get something wrong?

    • @malejacabezas9448
      @malejacabezas9448 5 ปีที่แล้ว +12

      Right. The erythrocytes doesn't have MHC-1 but they express CD47 in their surface (it does the same function).

    • @isidoratasic2058
      @isidoratasic2058 3 ปีที่แล้ว +4

      In order for NK cell to kill another cell it has to meet two criteria.
      1. Down regulation of MHC class I molecules
      2. Stress signals from the target cell to the NK which activates their cytotoxic activity.
      Erythrocytes meet the first criteria however they don’t send required stress signals to the NK cells (unless they want to be killed) thus not meeting the second criteria.
      Also they express CD47 marker as mentioned previously which inhibits NK activation.
      Hope this helps!

  • @stelwart170
    @stelwart170 ปีที่แล้ว

    Amazing review ❤️❤️❤️, thank you ninjaa

  • @rayanaall7971
    @rayanaall7971 2 ปีที่แล้ว

    I love your work, genius 😛

  • @user-lg4cw8oh9u
    @user-lg4cw8oh9u ปีที่แล้ว

    Thank you very much 😍

  • @happymweemba1260
    @happymweemba1260 ปีที่แล้ว +2

    this guy is great

  • @gattac900
    @gattac900 5 ปีที่แล้ว +2

    Holly shit that was awesome!!! Brian might explode if watched on typical 2x.

  • @user-ml5co8by4u
    @user-ml5co8by4u 3 หลายเดือนก่อน

    God-tier overview

  • @lalanto341
    @lalanto341 2 ปีที่แล้ว

    Zach the GOAT!

  • @krishnajagtap130
    @krishnajagtap130 3 ปีที่แล้ว +3

    Please make video on hypersensitivity reactions!!

  • @mujib4466
    @mujib4466 2 ปีที่แล้ว

    Thank you

  • @zhoisweet2740
    @zhoisweet2740 2 ปีที่แล้ว +2

    So did u get the prize ??

  • @SilenceInTheBliss
    @SilenceInTheBliss 3 ปีที่แล้ว

    What brilliance.

  • @doc.3li
    @doc.3li 3 ปีที่แล้ว

    That’s should make a lot of sense 👏🏻✨🥰

  • @user-oc6bn6sc5v
    @user-oc6bn6sc5v 10 หลายเดือนก่อน

    Thanks

  • @aayushbatra1147
    @aayushbatra1147 7 หลายเดือนก่อน

    U DESERVE A NOBEL PRIZE NOT ONLY A PRIZE❤

  • @meryem-bel
    @meryem-bel 13 วันที่ผ่านมา

    cannot thank youuuuu enouuuugh 😭🤍

  • @krijonsdulal9946
    @krijonsdulal9946 2 ปีที่แล้ว

    Thank you sir

  • @aliileleijuniortenari5091
    @aliileleijuniortenari5091 3 ปีที่แล้ว

    thank you

  • @Arendt-Foucault
    @Arendt-Foucault 4 ปีที่แล้ว +1

    I put all your videos on immune system at 2x, and it was crazy ! Amazing efficiency. I got the recap in one morning, holly shit, it was Great !

  • @brunaiglesias5542
    @brunaiglesias5542 7 หลายเดือนก่อน

    I think it would be interesting to include in an overview a couple comments on Th1 as well, just a suggestion

  • @Tsitsimpakos
    @Tsitsimpakos 4 ปีที่แล้ว +1

    Precious!

  • @goshjosh729
    @goshjosh729 5 ปีที่แล้ว

    Does the B cell not need direct T cell stimulation to become activated? Like TCR(T-cell)-MHC II(B-cell) activation?

  • @derscals4509
    @derscals4509 4 ปีที่แล้ว

    thanks from turkey

  • @AlohaUlises
    @AlohaUlises 6 ปีที่แล้ว

    Nice!!!!

  • @mo7eb720
    @mo7eb720 3 ปีที่แล้ว

    كفيت ووفيت 😮❤

  • @meryem-bel
    @meryem-bel 13 วันที่ผ่านมา

    cannot thank youuuuu enouuuuugh 😭