@@md8552 ashub19957@okiciciCould you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
My grandfather had Huntington's. I recall the day I was filling his cup of coffee and he said, "only half a cup". I thought it was because too much caffeine bothered him but he said no. He picks up his cup and it swings back and forth. He then said ,"if you pour me more than half a cup I still only get half a cup". It was weird to watch because it would stop swinging by the time he got the cup to his lips. He did not show signs until his late 60s and then he had a stroke at 76 and died at 78. He never seemed to be depressed or lacking cognition until maybe after his stroke. He did not seem to be deeply afflicted. I suppose I should get my DNA checked for the presence of the gene(s).
If your grand father has this disease then some body in your fathers generation maight have it. If your father is phenotypically ok ( then he might not inherited the faulty chromosome ) then you should be ok.
@@animatedbiologywitharpan Well it happens to be my mothers father, but it is autsomal so that makes no difference. She shows no sign of having it so far and is 75 years old. So maybe I don't carry that gene.
Hi, Arpan; lovely representation. I want to add some new lines. There is evidence that Huntington aggregates also affect muscle health. It is not restricted to neurons. Muscle Huntington aggregates can affect motor activity that's what evidence say (though these are looked poorly). Also, the aggregates are found in muscle cells. Muscle Huntington aggregates affect homeostatic synaptic plasticity. These can be rescued by expressing specific heat shock proteins. I have worked with various repeats and tested many chaperones, which I am not disclosing here as these are under communication. Major part of my postdoc work is understanding muscle Huntington disease.
Thanks for giving elaborate feed back . I agree to the points you have suggested. I am thinking of making a series of video were advanced concepts and open questions can be discussed. This video was for broad and general audiance.
Good evening sir I am Mahalekshmi a MBBS student from kottayam medical college I usually watch your videos for the reference and it helped me a lot.... Me and my friends also refer this channel during the revision of EXAMINATION times I am really says that ur classes are so well explained THANKS A LOT SIR FOR UR VIDEOS Our support will always with you sir I will share ur channel to the maximum..... And I am sure that ur channel will reach to big audience and it will reach to higher goals ........ ALL THE VERY BEST WISHES SIR🙏🙏🙏🙏
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.
Hi. My Mother in law was diagnosed with HD chorea eight years back. She suffered a lot and we lost her about a year back. My husband is now 36 years old. He recently found that he is facing focus issues in his work. So we thought of getting a genome test for the HD through MEDGENOME LABS, BENAGULU. sadly the result came positive it's been a couple of weeks since the result, still trying to cope up. We have an 8 year old daughter and we worry about her a lot. In India awareness about HD disease is null. Hope some work is done in the coming future.
I am so sorry to hear that. I agree Indian awareness is less. The risk of Huntington for your daughter is 50-50 as HT is autosomal dominant. This is sadly a high chance of having HT.
My dad had it. There is so less awareness regarding this in India yet so many are suffering. So many neurological doctors also dont know about this disease. It was heartbreaking to see father in so much pain and now i want to get genetic testing. But cant find any genuine lab which will do the testing. If any one knows kindly guide me. Thanks❤
Hi. My Mother in law was diagnosed with HD chorea eight years back. She suffered a lot and we lost her about a year back. My husband is now 36 years old. He recently found that he is facing focus issues in his work. So we thought of getting a genome test for the HD through MEDGENOME LABS, BENAGULU. sadly the result came positive it's been a couple of weeks since the result, still trying to cope up. We have an 8 year old daughter and we worry about her a lot. In India awareness about HD disease is null. Hope some work is done in the coming future.
My mother had it, and we are two sisters, now at the age of 26,and 28,and thinking about not to marry anyone, not want to spread this hd to our generation. Its very pathetic..
@@animatedbiologywitharpan this problem in DNA , meri nana koi bhi tha , phir 3 child of my nana effect , 2 death 1 alive she is my Massi, my mom not more now.& Mama
Thank you sooo much
@@md8552 ashub19957@okiciciCould you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
summarized and informative .thank you for your effort .
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
@@animatedbiologywitharpan I would be happy to do so . 🙏🏿🌹🫀
My grandfather had Huntington's. I recall the day I was filling his cup of coffee and he said, "only half a cup". I thought it was because too much caffeine bothered him but he said no. He picks up his cup and it swings back and forth. He then said ,"if you pour me more than half a cup I still only get half a cup". It was weird to watch because it would stop swinging by the time he got the cup to his lips. He did not show signs until his late 60s and then he had a stroke at 76 and died at 78. He never seemed to be depressed or lacking cognition until maybe after his stroke. He did not seem to be deeply afflicted. I suppose I should get my DNA checked for the presence of the gene(s).
If your grand father has this disease then some body in your fathers generation maight have it. If your father is phenotypically ok ( then he might not inherited the faulty chromosome ) then you should be ok.
@@animatedbiologywitharpan Well it happens to be my mothers father, but it is autsomal so that makes no difference. She shows no sign of having it so far and is 75 years old. So maybe I don't carry that gene.
@@shawnmulberry774 ya then most likely your mom didnot inherit the faulty chromosome . In that context you are out of risk.
Hi, Arpan; lovely representation. I want to add some new lines. There is evidence that Huntington aggregates also affect muscle health. It is not restricted to neurons. Muscle Huntington aggregates can affect motor activity that's what evidence say (though these are looked poorly). Also, the aggregates are found in muscle cells. Muscle Huntington aggregates affect homeostatic synaptic plasticity. These can be rescued by expressing specific heat shock proteins. I have worked with various repeats and tested many chaperones, which I am not disclosing here as these are under communication. Major part of my postdoc work is understanding muscle Huntington disease.
Thanks for giving elaborate feed back . I agree to the points you have suggested. I am thinking of making a series of video were advanced concepts and open questions can be discussed. This video was for broad and general audiance.
Chorea and it's Associated Conditions | Neurophysiology by Dr. Najeeb
th-cam.com/video/saDWYvbukQE/w-d-xo.html
Good evening sir
I am Mahalekshmi a MBBS student from kottayam medical college I usually watch your videos for the reference and it helped me a lot....
Me and my friends also refer this channel during the revision of EXAMINATION times
I am really says that ur classes are so well explained
THANKS A LOT SIR FOR UR VIDEOS
Our support will always with you sir
I will share ur channel to the maximum.....
And I am sure that ur channel will reach to big audience and it will reach to higher goals ........
ALL THE VERY BEST WISHES SIR🙏🙏🙏🙏
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
@@animatedbiologywitharpan sure sir
Chorea and it's Associated Conditions | Neurophysiology by Dr. Najeeb
th-cam.com/video/saDWYvbukQE/w-d-xo.html
Very beautiful and successful especially explaination on pictures
My favorite way 🙏
Please share my channel link with your friends and help me to reach big audiance.
Hi! Thank you for this video :) Could you please provide the sources for the information discussed?
www.nature.com/articles/nrdp20155
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
@@animatedbiologywitharpan yes of course !
Thank you very much
哈哈哈，讲得挺细致，收藏一个
In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.
Hi. My Mother in law was diagnosed with HD chorea eight years back. She suffered a lot and we lost her about a year back. My husband is now 36 years old. He recently found that he is facing focus issues in his work. So we thought of getting a genome test for the HD through MEDGENOME LABS, BENAGULU.
sadly the result came positive it's been a couple of weeks since the result, still trying to cope up. We have an 8 year old daughter and we worry about her a lot.
In India awareness about HD disease is null. Hope some work is done in the coming future.
I am so sorry to hear that. I agree Indian awareness is less. The risk of Huntington for your daughter is 50-50 as HT is autosomal dominant. This is sadly a high chance of having HT.
My dad had it. There is so less awareness regarding this in India yet so many are suffering. So many neurological doctors also dont know about this disease. It was heartbreaking to see father in so much pain and now i want to get genetic testing. But cant find any genuine lab which will do the testing. If any one knows kindly guide me. Thanks❤
I am so sorry to hear this. The sequencing can be quite costly. CDFD hyderabad can do it possibly
@@animatedbiologywitharpan thank you🙏
Hi. My Mother in law was diagnosed with HD chorea eight years back. She suffered a lot and we lost her about a year back. My husband is now 36 years old. He recently found that he is facing focus issues in his work. So we thought of getting a genome test for the HD through MEDGENOME LABS, BENAGULU.
sadly the result came positive it's been a couple of weeks since the result, still trying to cope up. We have an 8 year old daughter and we worry about her a lot.
In India awareness about HD disease is null. Hope some work is done in the coming future.
In my family fifth generation started huntingeon disease what to do stop this disease
Could you please contact me at arpanparichha1994@gmail.com. I will send my contact we can talk
My mother had it, and we are two sisters, now at the age of 26,and 28,and thinking about not to marry anyone, not want to spread this hd to our generation. Its very pathetic..
i am so sorry to hear that
I have my mom video , she have had chorea 24hrs 60 sec full body vibration , i don't want to upload that
So sorry to hear that
@@animatedbiologywitharpan this problem in DNA , meri nana koi bhi tha , phir 3 child of my nana effect , 2 death 1 alive she is my Massi, my mom not more now.& Mama
Chorea and it's Associated Conditions | Neurophysiology by Dr. Najeeb
th-cam.com/video/saDWYvbukQE/w-d-xo.html