What are some of the major causes of hemolytic anemia? Find out in this video. For more information, look at Robbins and Cotran: Pathological Basis of Disease, Chapter 14.
Thank you very much. I appreciate your presentation on the basic foundations of and detection parameters of AIHA/IMHA/HA conditions. I am a 34yo preparing for medical school and am giving a high level presentation on this class of disorder in an immunology study group. Thank you for making this presentation available for others to watch.
Just a note about G6PD deficiency, it's also known as Favism. Eating legumes especially fava beans increases oxidative stress on RBCs leading to hemolytic crisis in those with it. This seems "out there" but it came up in my second year med exams.
+Jordan iguess I did not know this. And the bean market tells you that beans are good for you. I do not overeat those fart generating suckers that much. I am going to look into this deeper. Fava beans are rediculously good though I will admit.
I thought the speed was good but only because pre-reading first and watched this as a summary. I can imagine that if this video is your first exposure to such material, it would be a difficult tutorial in terms of the speed. Great tutorial though! Thank you!!!!
My dog was sprayed by a skunk and got a rabies booster. A few weeks later she had to go to the emergency vet, and almost died due to this. The emergency vet was amazing. He said sometimes the booster causes the immune system goes haywire. Thankfully she made it through. She's back to being a young and strong pup. We supplemented her diet with Chlorophyllin, along with all the medications she received. She was green for weeks. After we started giving it to her, her health increased so much.
is it anti-rbc antigen or antibody? i understand it as anti-autoantibodies in coomb's reagent binding to the anti-rbc antibodies attached to the rbc surface.
Whenever we did a blood smear in anatomy, I struggled finding leukocytes. I had a blood test done and they concluded my erythrocyte count was low. They also said my iron levels were normal. Anyone know what's wrong with me?
Hi, as haemolytic anemia is considered the destruction of RBCs and thalassemia is considered the underproduction of RBCs as it limits globin production for haemoglobin, and does not destroy the RBCs, how is thalassemia considered haemolytic? Thanks.
Can you get rid of Hemolytic anemia? I been dealing with this Illness for the pass 20 years, the past last years I been getting a lot of blood clots lungs and brain. If feel like my doctor does not care any more or just not know what to do. Can some one help me, please!
I have a lot of question, because my 1 year old baby has hemolytic anemia. His hemoglobin dropped to 5.0. We just found out last december And stayed at the hospital for 9 days, and also he got blood transfusion once. We are still waiting for the other result to find out if is it severe or not. Im just worried. I am willing to ask in a private message. Thank you.
In thalassemia hemolytic anemia we have microcytic microchromic anemia because the delay of production in the chains (a or b) causes an extra-unnecessary cell division thus the smaller MCV/MCH of the red blood cells. The reticulocyte percent is higher because the bone marrow is not having any blood cell production issues. Erythropoiesis works fine but the produced RBC have an abnromal amount of chains in them and that causes them to be destroyed by the spleen.
I agree with Naji :( The videos are really helpful, but I have to pause and rewind a bit multiple times because you're going too fast. Nevertheless, thank you very much!
Just wonderful, I been tryin to find out about "beets thyroid" for a while now, and I think this has helped. Ever heard of - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some super things about it and my buddy got amazing results with it.
I have a question that is bit out of the topic: what makes the stored blood different than the fresh blood and why does the stored blood has higher hemolysis? Thank you very much.
The transfused blood is different from the blood of the person receiving the transfusion. Red blood cells (RBCs) have a number of molecules on their extracellular surface (these are called antigens). The kind of antigens present determine what blood type the person has - like the ABO system, or the Rh system (but there are lots of others). It is the sum of the different antigens present that makes a person's blood unique. In a blood transfusion, while the major blood type antigens can be matched from donor to recipient, it is likely that at least some of the antigens will not match. The recipient's body will recognize these antigens as foreign, and destroy those cells, which causes the hemolytic anemia. The amount of hemolysis itself is likely dependent on a number of factors - number and type of antigens matched and mismatched, strength of the immune system of the recipient, other drugs in the system, etc. It is a very complex system, and it is still being figured out. I hope that helps.
daf189 Oh yeah, and what about if the blood that was collected was stored is it likely to go under hemolysis and what causes it to if its not in the body? But the thing about antigens was clear. Thank you very much, it was really helpful.
Afra H Blood that is stored outside of the body will not last forever. In the US, blood must be used within 42 days. Hemolysis within the sample (while outside of the body) is possible outcome, but it is monitored for. If more than 1% of the cells are hemolyzed, the blood cannot be used. You can read more about it here: en.wikipedia.org/wiki/Blood_bank#RBC_storage_lesion.
+collerthanme the mosquito that causes malaria injects cells from its salivary glands into the blood stream, so essentially there are RBCs that are infected, hence hemolytic anaemia
After pregnancy, most women lose lots of blood that's the main reason anemia in women and its recover take most of the month but the help of Ayurveda Anemia Care Pack by Planet Ayurveda very helpful for those women and men whose face anemia.
this is a bit too ''advanced'' and i mean him using RBC instead of saying red blood cells, talking fast and not explaining words like ''hemoglobin'' and such (i know what it means but not everyone can understand these vids)
+Posh Twat Not at all if you are well studied on the foundations of biology. Most undergraduate biology level courses will prepare you to keep up with what he is talking about. I completely understood everything that he was talking about at the pace he was discussing it. Not because I am special but because I am well studied thus far in biology at the university level. I am 99% complete with my undergrad and preparing to enter medical school soon. Just keep reading, keep studying, keep your head up and all of this will start to come very easy for you.
Thank you very much. I appreciate your presentation on the basic foundations of and detection parameters of AIHA/IMHA/HA conditions. I am a 34yo preparing for medical school and am giving a high level presentation on this class of disorder in an immunology study group. Thank you for making this presentation available for others to watch.
Very good! This cleared up a lot of things for me. Thank you
wow, too much information in a little time, I adored this.
Cool video. It reminded me of school. i work at a hospital lab. We see this all the time
Very formative
Really thank you
I feel like god sent you to save my grades!! THANKSS!!!!
Just a note about G6PD deficiency, it's also known as Favism. Eating legumes especially fava beans increases oxidative stress on RBCs leading to hemolytic crisis in those with it. This seems "out there" but it came up in my second year med exams.
+Jordan iguess I did not know this. And the bean market tells you that beans are good for you. I do not overeat those fart generating suckers that much. I am going to look into this deeper. Fava beans are rediculously good though I will admit.
Thank you Mr. Godsend.
such an amazing video!
excellent video, thanks!
Thank you .. very informative
Brilliant video.
I thought the speed was good but only because pre-reading first and watched this as a summary. I can imagine that if this video is your first exposure to such material, it would be a difficult tutorial in terms of the speed. Great tutorial though! Thank you!!!!
Wow... excellent, very clear. #makingmedschooleasier
excellent presentation
Super good summary! An awesome, helpful video! XOXOXO
My dog was sprayed by a skunk and got a rabies booster. A few weeks later she had to go to the emergency vet, and almost died due to this. The emergency vet was amazing. He said sometimes the booster causes the immune system goes haywire. Thankfully she made it through. She's back to being a young and strong pup. We supplemented her diet with Chlorophyllin, along with all the medications she received. She was green for weeks. After we started giving it to her, her health increased so much.
excellent video
Thanks again brohther !!! :)
Wow, I wish you were my medtech professor!
What program are you using???? it's pretty cool!
Amazing ! :)
Part 1 missing for some reason? :(
is it anti-rbc antigen or antibody?
i understand it as anti-autoantibodies in coomb's reagent binding to the anti-rbc antibodies attached to the rbc surface.
Whenever we did a blood smear in anatomy, I struggled finding leukocytes. I had a blood test done and they concluded my erythrocyte count was low. They also said my iron levels were normal. Anyone know what's wrong with me?
Hi, as haemolytic anemia is considered the destruction of RBCs and thalassemia is considered the underproduction of RBCs as it limits globin production for haemoglobin, and does not destroy the RBCs, how is thalassemia considered haemolytic? Thanks.
Can you get rid of Hemolytic anemia?
I been dealing with this Illness for the pass 20 years, the past last years I been getting a lot of blood clots lungs and brain.
If feel like my doctor does not care any more or just not know what to do.
Can some one help me, please!
I would like to know how hemoglobin H is detected.
I have a lot of question, because my 1 year old baby has hemolytic anemia. His hemoglobin dropped to 5.0. We just found out last december And stayed at the hospital for 9 days, and also he got blood transfusion once. We are still waiting for the other result to find out if is it severe or not. Im just worried. I am willing to ask in a private message. Thank you.
Awesome video, would just slow down a little, especially to allow viewers to absorb what you just said and emphasise what is important.
really good! wich program did you use?
Victor OliveiraNice video but schistocytes is for malaria and schizocytes for red cells damage
Just question
How is thalassemia hemolytic anemia and microcytic microcytic anemia.
And so what is the reticulocyte percent in thalassemia
Thanks
I have exactly the same question to you. Did you find the answer, plz tell me?
Yes I have.
It's just classification
Tow kind of classification
The first one up to the reticulocyte count
And the second one up to RBCs size MCV
In thalassemia hemolytic anemia we have microcytic microchromic anemia because the delay of production in the chains (a or b) causes an extra-unnecessary cell division thus the smaller MCV/MCH of the red blood cells. The reticulocyte percent is higher because the bone marrow is not having any blood cell production issues. Erythropoiesis works fine but the produced RBC have an abnromal amount of chains in them and that causes them to be destroyed by the spleen.
I agree with Naji :( The videos are really helpful, but I have to pause and rewind a bit multiple times because you're going too fast.
Nevertheless, thank you very much!
Yasmine Mansouri hahhaa me too!
Just wonderful, I been tryin to find out about "beets thyroid" for a while now, and I think this has helped. Ever heard of - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some super things about it and my buddy got amazing results with it.
thankyou :)
I have a question that is bit out of the topic:
what makes the stored blood different than the fresh blood and why does the stored blood has higher hemolysis?
Thank you very much.
The transfused blood is different from the blood of the person receiving the transfusion. Red blood cells (RBCs) have a number of molecules on their extracellular surface (these are called antigens). The kind of antigens present determine what blood type the person has - like the ABO system, or the Rh system (but there are lots of others). It is the sum of the different antigens present that makes a person's blood unique. In a blood transfusion, while the major blood type antigens can be matched from donor to recipient, it is likely that at least some of the antigens will not match. The recipient's body will recognize these antigens as foreign, and destroy those cells, which causes the hemolytic anemia. The amount of hemolysis itself is likely dependent on a number of factors - number and type of antigens matched and mismatched, strength of the immune system of the recipient, other drugs in the system, etc. It is a very complex system, and it is still being figured out. I hope that helps.
daf189 Oh yeah, and what about if the blood that was collected was stored is it likely to go under hemolysis and what causes it to if its not in the body? But the thing about antigens was clear.
Thank you very much, it was really helpful.
Afra H Blood that is stored outside of the body will not last forever. In the US, blood must be used within 42 days. Hemolysis within the sample (while outside of the body) is possible outcome, but it is monitored for. If more than 1% of the cells are hemolyzed, the blood cannot be used. You can read more about it here: en.wikipedia.org/wiki/Blood_bank#RBC_storage_lesion.
daf189 I appreciate it, thank you
Tq🙏🙏
thanks a lot very clear and interesting....but don,t you think that you are talking too fast?!!!
plz help me
How malaria causes an haemolytic anaemia?
+collerthanme the mosquito that causes malaria injects cells from its salivary glands into the blood stream, so essentially there are RBCs that are infected, hence hemolytic anaemia
nice
ppl complaining about the speed. And here i am watching at 2x speed lol
Great video, thanx :)
After pregnancy, most women lose lots of blood that's the main reason anemia in women and its recover take most of the month but the help of Ayurveda Anemia Care Pack by Planet Ayurveda very helpful for those women and men whose face anemia.
are u reading news .???? soon fast not help ful
this is a bit too ''advanced'' and i mean him using RBC instead of saying red blood cells, talking fast and not explaining words like ''hemoglobin'' and such (i know what it means but not everyone can understand these vids)
+Marina Gontie In the previous videos, he already explained all of those terms.
Derek Brown i hadnt even watched, and didnt exactly have the time to lol i was watching this/learning for an exam a day later.
+Posh Twat Not at all if you are well studied on the foundations of biology. Most undergraduate biology level courses will prepare you to keep up with what he is talking about. I completely understood everything that he was talking about at the pace he was discussing it. Not because I am special but because I am well studied thus far in biology at the university level. I am 99% complete with my undergrad and preparing to enter medical school soon. Just keep reading, keep studying, keep your head up and all of this will start to come very easy for you.