2016 Roy Walford lecture: NAD, Sirtuins and Aging - Leonard P. Guarente, PhD

แชร์
ฝัง

ความคิดเห็น • 20

  • @Idahomie
    @Idahomie 3 ปีที่แล้ว +4

    Amazing what has evolve d in biochemistry in the 47 years since my first biology class. Modern scientific miracles' of hope in these otherwise dark days.

  • @scottwilliams2136
    @scottwilliams2136 4 ปีที่แล้ว +6

    For very different reasons, NAD+ has also attracted a wave of attention from cancer researchers. Recent studies suggest that cancer cells of many types depend on NAD+ to sustain their rapid growth and that cutting off the NAD+ supply could be an effective strategy for killing certain cancers. The data from these studies paint a more complicated picture of NAD+ and raise new questions about the diverse ways taking an NAD+-boosting supplement might influence health. “It might still slow down the aging part, but it might fuel the cancer part,” says Versha Banerji, a clinician-scientist at the University of Manitoba. “We just need to figure out more about the biology of both of those processes, to figure out how we can make people age well and also not get cancer.” This is just a fellow up to my previous post. Interesting that most sites are ignoring the possibilities of its effects on cancer.

    • @catman4471
      @catman4471 3 ปีที่แล้ว

      This has been covered elsewhere but the bottom line is that there has been no studies that suggest that NAD+ pre-cursors cause cancer, but they can accellerate existing cancer. th-cam.com/video/-04-1OX4RVM/w-d-xo.html

    • @marionharris5952
      @marionharris5952 ปีที่แล้ว

      Good point. Analogous to photobiomodulation.

  • @psiclops521
    @psiclops521 4 ปีที่แล้ว +13

    What I get from this is that, at this point in human history, mice must be healthier than ever in their existence due to the massive number of medical breakthroughs.

    • @markpatrick2735
      @markpatrick2735 4 ปีที่แล้ว +1

      sliced and diced is rarely healthy or any lifeform

    • @catman4471
      @catman4471 3 ปีที่แล้ว

      Yes, one day mice will rule the world.

  • @antMight
    @antMight ปีที่แล้ว

    Super, thank you for a video. I’m passionate about aging and supplements to do it possible 🙂

  • @fondrees
    @fondrees 3 ปีที่แล้ว +1

    What does this have to do with roy walford?

  • @abdullayt588
    @abdullayt588 2 ปีที่แล้ว +1

    wow

  • @rezarabbi7419
    @rezarabbi7419 2 ปีที่แล้ว +1

    Nice

  • @rui-9-cs315
    @rui-9-cs315 3 ปีที่แล้ว +1

    💕

  • @petercoderch589
    @petercoderch589 2 ปีที่แล้ว

    Audio so low couldn't understand anything.

  • @biogerontology7646
    @biogerontology7646 3 ปีที่แล้ว

    26:35 organoid colonies

  • @ganje3869
    @ganje3869 5 ปีที่แล้ว +1

    Looks like it works hand is hand with the endocannabanoid system.

  • @sheafisher3578
    @sheafisher3578 6 ปีที่แล้ว +2

    So now the whole pro-SIRT/anti-mTOR view is complicated by the intervening deacetylation of S6K1.

    • @fondrees
      @fondrees 3 ปีที่แล้ว

      Doris loh nade me aware of this connection. Brilliant woman.

    • @fondrees
      @fondrees 3 ปีที่แล้ว +1

      Why doesnt David sinclair mention this. Surely he is aware. Sometimes i think he is nothing but a snake oil salesman.1st the resveratrol fiasco, which was his first miracke cure. Now NAD. It certainky does make sense that NAD WOULD PROMOTE CANCER AS WELL AS YOUTH.