Translation (mRNA to protein) | Biomolecules | MCAT | Khan Academy
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- เผยแพร่เมื่อ 8 ก.พ. 2025
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A deep dive into how mRNA is translated into proteins with the help of ribosomes and tRNA.
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This is the most clearly explained video on translation I have watched. Simplifies the complex concept. Thank you Khan Academy and the tutor.
Sir your teaching is exceptional. I have been struggling to find a good and clear explanation of translation all over youtube but couldn't find one. But guess what. I stumbled upon your beautiful and super simple explanation of the same. Thank you so much.
I've always had this problem with these sites in ribosome, like what are they exactly and what are they for?- and now it's clear. Sal you are a blessing ♥
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This is so awesome and so clear!! You made this fascinating process come to life and this video wasn’t even animated!! Thank you sir for all you do!!
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Top Tier explanation. Thank you so much. My book messed up this explanation even if it is quite simple.
Guys, I am still puzzled with one question: So we have Chromosomes -> DNA in a nucleus of the cell. Then, we have Translation phase where we get Proteins, but where do Proteins live? Do they live inside the cell (cytoplasm) ? So each cell creates it's own Proteins or each cell creates different proteins and they leave the cell and work 'outside' the cell? And in this case, what is 'outside' the cell? Any material/video, explaining this are more then welcome!
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WOW... My professor took TOO LONG to explain this. I needed the visuals
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During and after translation, polypeptides may need to be modified before they are biologically active. Post-translational modifications include:
removal of translated signal sequences-short tails of amino acids that aid in directing a protein to a specific cellular compartment
proper “folding” of the polypeptide and association of multiple polypeptide subunits, often facilitated by chaperone proteins, into a distinct three-dimensional structure
proteolytic processing of an inactive polypeptide to release an active protein component, and
various chemical modifications (e.g., phosphorylation, methylation, or glycosylation) of individual amino acids.
20 fewer pages of my $150 textbook I will have to read tonight. Thank you good sir.
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Best explanation ever👏
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Awesome! Thank you
The explanation is just wow
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Super helpful I now fully understand
legendary biology teacher
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Thanks sir
I tried to learn Translation but failed…
But your video has cleared all my concepts about translation.😊
May God bless you
i think i missed a detail- does the ribosome float around and kind grab tRNA or are they drawn towards it? or what? how does the ribosome come in contact with tRNA?
crazy how in 15 minutes i learned more than from a 55 minute lecture
Than you SO MUCH for making this video!!! This helps a lot!!!
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Great video, explains tRNA and mRNA interactions so well. My mind can visualize it smoothly now. Also, super interesting fact about the antibiotics at the end!
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did you pass
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Saving my life yet again :)
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REALLY HELPFUL
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I just realized I am rewatching a video my teacher played for us yesterday. Lol. I didn't realize till the T and + confusion.
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This is wonderful. Thank you for a simplified version of translation. Sometimes i prefer watching these summarized videos than reading a book..But i got a question in relation to the 'E, P, A' sites how is it possible that we have an Exit on the 5' yet the mRNA is run thru the ribosome from 5' 3' direction ..Can you assist on that maybe i missed it
I think it is a mistake, the 5-3 direction should be opposite in that video to make sense. Evrything else seems to be okay.
its not a mistake. the E site is on 5' bc the ribosome is moving towards 3' but the codons are still at the same place. so the tRNA which is initially on p site shifts to the E site not bc it is moving towards 5' end but bc the ribosome is moving towards 3' end and the tRNA is still in its position.
this really help a lot thanks
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thank you!! finally get it
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Nice video. Some people may not know but proteins make up the majority of the biopharmaceutical market for use as a therapeutic