Transcription and mRNA processing | Biomolecules | MCAT | Khan Academy

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Introduction to transcription including the role of RNA polymerase, promoters, terminators, introns and exons.
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[@sophies8573]

This video is supposed to be for high school students and I'm a med student learning the exact same material 😂

[@leandro6285]

Same haha

[@adibsiddiki7409]

Sophie Van der Meer Well done on getting in, both of you. I'm hoping to.

[@muaazbutt9342]

And i thought i was alone xD

[@RS6y6]

I'm a med student too and I wish that this would be enough for the molecular cellbiology exam but it's not even close :'( Great video btw

[@cpard2d2]

I´m in a masters program and we´re learning this too. We go a bit deeper with the promoter sequences, transcription factors and the different polymerases but overall, it´s the same XD.

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this dude is so damn amazing.
His courses are free PLUS he hasn't any ads in his videos. Much Respect for this guy!

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Khan academy is a non profit that you can donate to

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Lol mines tc has all her vids in yt monetized 😂 doesn't even show up to class, just ask us to watch 15-18 vids per week

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the fact that you can digest all categories of subjects and then teach is mind boggling!

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I know right

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YYYEEESSS! Sal is a gift for all of us x

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Maybe he just reads from a script?

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@@jeromeyklein8838 Well, he did get a Bachelor of Science from MIT...

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[@unclelelax8341]

10 mins lecture > 5 hours lecture

[@aplus1080]

Naw, TikTok brain.

[@Devilsfannumber30]

if anyone wanted to know:
spliceosomes​ are what cut out sections from the RNA strand to remove the introns and leave the exons

[@schmidtythekidd]

Nerd

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thank you i needed it for my vocab !!

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@@schmidtythekidd i dont think he is a nerd tho, look at his pfp

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I have no idea how you taught me something I've been studying for two weeks in 10 minutes and I understood perfectly. I wish you were my professor! Keep it up for the pre-med students please!!!

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it's so weird how you always upload topics about exactly what i'm learning in class!

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advanced biology/ chemistry topics don't change often so it would make sense

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The AP bio and AP chem cuirculum dont really change or varry much school to school

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it makes sense he would change his upload topic schedule to coincide with what kids are learning in class.

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Anyone else feel the passion in his voice when he talks about these said topics?

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Thank you for this. This was extremely helpful!

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5:55-6:27 nothing you need to take notes on, but the reminder we all need! biology is amazing.

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This was so helpful for my university genetics class! thank you!

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I like how you don't just pass on the material but also pass on the passion

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This is amazing! I found it hard to understand in class because of how shallow it was, but with more details it makes perfect sense! Thanks a lot.

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same, this video is very clear o.O

[@clintluna6884]

Love the enthusiasm!! Awesome video! The Audio kept cutting out about every minute or so on my end, not sure if it's just me or anyone else??

[@Testimonyofabutterfly]

this was super helpful for learning this process! I am in awe of the creator God and his ability to make such a complex and beautiful process within such a small structure!!! Praise Jesus

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a whole lecture made ultra-clear in 10 minutes. thank you!!!

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6 years and this still save lives...

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This was really helpful for my last minute exam preparations ❤️❤️❤️ If it wasn't for youtube, I would've failed my uni exams.

[@djennings-DDS]

Great video - thank you. I liked the very clear explanation of Ribosomal RNA (that it doesn't need anything else to code, compared to the DNA where it needs Helicase, RNA Primers, Ligase, etc.) I also really enjoyed learning about the difference between the mRNA in prokaryotes vs. Eukaryotes. It's interesing that the Introns do not have a specific purpose, so the mRNA, is made up of what's left over after the splicing takes place (exons) of that "pre- mRNA".
Again - I greatly enjoyed this video, thank you!

[@aplus1080]

There is no dead weight in nature. I'm curious to see the mystery of introns resolved.

[@djennings-DDS]

@@aplus1080 I’ve pretty much forgotten everything about RNA and introns

[@fmsenga]

Thank you for this tutorial...harpers is quite tedious to understand...this helps a lot

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I wish this were around when I went to school. Thank you for the wonderful videos.

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RIP for Medved's exam, but this video made it much easier. Thanks and keep it up bro!

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Nice. This makes so much sense now

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This recap is just what i needed!

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I'm Korean university student. This explainment helps for Test. Thanks.

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you make mt life easy, stay blessed

[@marygonzalez864]

Does anyone know if there is a way to get a print out of the diagrams and pictures he shows. The way he explains all the processes with those visuals really help!

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you can always screenshot and crop into word doc instantly :)

[@fersiva1]

Hi Mr Khan, thanks for the explanantion but can you explain on the process on how the cap and tail is added and their purpose in conversion of pre mRNA to mRNA?

[@ilove0918]

you should upload more of DNA/RNA in depth processes!!

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I am so grateful for your videos! Thank you!

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Mr. Khan, you seem like an awesome human being to me. I really wish you could coach me in person. I got only 16 days left before my 12th grade final examinations start. Thanks a lot for doing what you're doing. That's really great work. Keep it up. I will donate when I am able to. ❤❤

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Me too as a fresh 12th grade student

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His cousins actually prefer him in videos than him in person, maybe it's the system that allows him to be as good as a teacher he is today :)

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You are very clear in your teaching Many thanks!

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Trust Khan Academy to provide more information than my government :D Thank you Sal, you're a real legend.

[@kuensedn1529]

2 yrs later i watch this once again! :))

[@TomDavis95]

Important to note that in eukaryotes the pre-mRNA processing occurs co-transcriptionally and not post-transcriptionally!

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thanks for helping on my Biology test!

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honestly as a hon bio student you save my life thank you

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You should always remember that Biology is amazing. Yeah man it really is!!

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This guy is awesome...

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This dude seriously has a video for everything

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God Is Great, May God Bless them all and you all and your families

[@sciencenerd7639]

turns out helicases are involved in transcription after all
still a great video, keep up the good work Khan Academy, thanks!

[@allysonperez5241]

I love how you get excited about the material. Makes us students much more engaged and excited too. Endless thank yous Sal!!

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Thank you soo much that was an 1.30 h lecture of nonsense that u just turned into the most interesting and understandable information in 10.24 mins

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You are the best teacher I have ever seen

[@abdidahirmohamud7353]

thanks for the video. it really helped me a lot understanding that

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Awesome video, in general awesome videos. I study Applied Biology and it's great to have your videos and from there read further into the subject. Thanks a lot! (also, this is great for getting an overview since I have no idea how to get all the biology stuff in my head I need to know in three days)

[@loisbeard8536]

Hi, thank you for your hard work, it’s an amazing lesson! But I don’t quite understand the way mRNA develops towards 3’ instead 5’? Thanks

[@momin665]

Amazing sir and
made my day God bless you

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You’re amazing thank you teaching us all😁

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Really thank you you helped me alot❤

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love that my professor for my 400 level biochem class assigned us to watch this video

[@chelsieb.593]

i don't know how many times throughout my biology career, I've had to rewatch this video

[@icaass2727]

thanks for the video, such a very good video :))
but just realized that all cromosome or nucleus or enzyme or even protein picture we see in our textbooks or internet just an animation, so it's must be very very complicated in the real life. yet that's all are fascinating things to know about

[@user-mv9lc6uf4t]

Thanks for the great explanation 🌹

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omg amazing Thanks from very bottom of my heart

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SUCH AN AMAZING VIDEO THANK YOU SO MUCH!!!!!

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I’m literally watching this before my exam please wish me luck

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what did you get?

[@alltup8347]

@@Star-pj8fz 34/50

[@Star-pj8fz]

I got a 75%. I hate biology 😂

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Thanks a lot that a amazing explain..

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so beautiful. great diagrams

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*Me: YAWNs
Biology: *am I a joke to you?

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Sal Khan came to my school a few years ago... it was cool. Except I'm dumb and can't understand anything.

[@ritikasrivastava3840]

thankyou soo much for the best explanation

[@moustafazain3833]

that is amazing ty very much

[@ElloBoppit]

It is mentioned in this video that the RNA Polymerase is more than enough to open the DNA and begin transcription. However, in my Kaplan biochem 2020 MCAT prep booklet it says that RNA Pol II is preceded by helicases & topoisomerases to address unwinding/supercoiling. So both work?

[@JorgeRamos-xw6dy]

I am in awe!!!

[@Goldielopss]

I needed this exact video a year ago :'C

[@020.bharathraj.s5]

Very Good lecture. Keep it up.

[@mdijkman9386]

Since this video has been uploaded one thing has been discovered. In termination, right after the hairpin is formed a bunch of Adenine's are present in the DNA, this makes it so that A lot Uracil's are transcribed. The bond between A en U (also T) is quite weak, with only 2 hydrogen bonds formed. So the pre-mRNA falls off.

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i learn more from sal than i do from my own professors

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i rememver watching this in high school and now im in my gap years. and im. still watching this

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M in 1st year medicine and m watching this coz it's very helpful 🤪😅🔥

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THANK YOU SO MUCH!!