I´m in a masters program and we´re learning this too. We go a bit deeper with the promoter sequences, transcription factors and the different polymerases but overall, it´s the same XD.
I have no idea how you taught me something I've been studying for two weeks in 10 minutes and I understood perfectly. I wish you were my professor! Keep it up for the pre-med students please!!!
Great video - thank you. I liked the very clear explanation of Ribosomal RNA (that it doesn't need anything else to code, compared to the DNA where it needs Helicase, RNA Primers, Ligase, etc.) I also really enjoyed learning about the difference between the mRNA in prokaryotes vs. Eukaryotes. It's interesing that the Introns do not have a specific purpose, so the mRNA, is made up of what's left over after the splicing takes place (exons) of that "pre- mRNA". Again - I greatly enjoyed this video, thank you!
this was super helpful for learning this process! I am in awe of the creator God and his ability to make such a complex and beautiful process within such a small structure!!! Praise Jesus
Wonderful! I'm getting my TH-cam degree. I navigate from MIT to Harvard to UC Berkeley etc...all for free lol. I wish this were around when I went to school. Thank you for the wonderful videos.
Mr. Khan, you seem like an awesome human being to me. I really wish you could coach me in person. I got only 16 days left before my 12th grade final examinations start. Thanks a lot for doing what you're doing. That's really great work. Keep it up. I will donate when I am able to. ❤❤
Thank you so much for this video!! You're the best! Your handwriting is nice and the way you explain it is so much more interesting. I always have more appreciation of what we're learning because of the way you teach it in these KA Videos.
Since this video has been uploaded one thing has been discovered. In termination, right after the hairpin is formed a bunch of Adenine's are present in the DNA, this makes it so that A lot Uracil's are transcribed. The bond between A en U (also T) is quite weak, with only 2 hydrogen bonds formed. So the pre-mRNA falls off.
Hi Mr Khan, thanks for the explanantion but can you explain on the process on how the cap and tail is added and their purpose in conversion of pre mRNA to mRNA?
It is mentioned in this video that the RNA Polymerase is more than enough to open the DNA and begin transcription. However, in my Kaplan biochem 2020 MCAT prep booklet it says that RNA Pol II is preceded by helicases & topoisomerases to address unwinding/supercoiling. So both work?
5:28 The RNA being transcripted has the same sequence as the coding strand (with the Uracil replacing Thymine), BUT they don't have "the same information". If the coding strand were being transcribed here, it'll give a different RNA sequence, therefore a different order of codons, which eventually gives different amino acids (different protein). So yeah, not the same information =)
Thanks.what is the primary,secondary,tertiary and quaternary structure of DNA??and how hydrogen bonds contributed in stability of DNA?l want answers please
Umm no , I guess you are talking about the anti codon end of tRNA , in all types of RNA the Thymine is replaced with Uracil not only in tRNA but also in mRNA.
Awesome video, in general awesome videos. I study Applied Biology and it's great to have your videos and from there read further into the subject. Thanks a lot! (also, this is great for getting an overview since I have no idea how to get all the biology stuff in my head I need to know in three days)
hi. just a question because i got confused. I am currently reading Harper's Medical Biochemistry. i usually watch your videos when i can't understand the book. According to Harper, the strand that is transcribed or copied into and RNA molecule is referred to as the template strand, and the other DNA strand, the non coding strand, is frequently referred to as the coding strand. I think you interchanged the terms in your video. Can you please clarify these things. Thank you so much!
thanks for the video, such a very good video :)) but just realized that all cromosome or nucleus or enzyme or even protein picture we see in our textbooks or internet just an animation, so it's must be very very complicated in the real life. yet that's all are fascinating things to know about
this dude is so damn amazing.
His courses are free PLUS he hasn't any ads in his videos. Much Respect for this guy!
Khan academy is a non profit that you can donate to
Lol mines tc has all her vids in yt monetized 😂 doesn't even show up to class, just ask us to watch 15-18 vids per week
This video is supposed to be for high school students and I'm a med student learning the exact same material 😂
Same haha
Sophie Van der Meer Well done on getting in, both of you. I'm hoping to.
And i thought i was alone xD
I'm a med student too and I wish that this would be enough for the molecular cellbiology exam but it's not even close :'( Great video btw
I´m in a masters program and we´re learning this too. We go a bit deeper with the promoter sequences, transcription factors and the different polymerases but overall, it´s the same XD.
the fact that you can digest all categories of subjects and then teach is mind boggling!
I know right
YYYEEESSS! Sal is a gift for all of us x
Maybe he just reads from a script?
@@jeromeyklein8838 Well, he did get a Bachelor of Science from MIT...
@@jeromeyklein8838 GFY
if anyone wanted to know:
spliceosomes are what cut out sections from the RNA strand to remove the introns and leave the exons
Nerd
thank you i needed it for my vocab !!
@@schmidtythekidd i dont think he is a nerd tho, look at his pfp
@@KanekiKen-vm7zq your comment 😂😂
I have no idea how you taught me something I've been studying for two weeks in 10 minutes and I understood perfectly. I wish you were my professor! Keep it up for the pre-med students please!!!
Anyone else feel the passion in his voice when he talks about these said topics?
it's so weird how you always upload topics about exactly what i'm learning in class!
advanced biology/ chemistry topics don't change often so it would make sense
The AP bio and AP chem cuirculum dont really change or varry much school to school
it makes sense he would change his upload topic schedule to coincide with what kids are learning in class.
10 mins lecture > 5 hours lecture
Naw, TikTok brain.
I never imagined that one day Khan Academy videos would become so nostalgic to me
I wish I would have found this while I was in microbiology, You explained in ten minutes what I couldn't even get from tutoring.
This is amazing! I found it hard to understand in class because of how shallow it was, but with more details it makes perfect sense! Thanks a lot.
same, this video is very clear o.O
This helped me a lot to understand the processes in the different cells. Thank you a lot!
Great video - thank you. I liked the very clear explanation of Ribosomal RNA (that it doesn't need anything else to code, compared to the DNA where it needs Helicase, RNA Primers, Ligase, etc.) I also really enjoyed learning about the difference between the mRNA in prokaryotes vs. Eukaryotes. It's interesing that the Introns do not have a specific purpose, so the mRNA, is made up of what's left over after the splicing takes place (exons) of that "pre- mRNA".
Again - I greatly enjoyed this video, thank you!
There is no dead weight in nature. I'm curious to see the mystery of introns resolved.
@@aplus1080 I’ve pretty much forgotten everything about RNA and introns
this was super helpful for learning this process! I am in awe of the creator God and his ability to make such a complex and beautiful process within such a small structure!!! Praise Jesus
This person has helped me better understand chemistry, trigonometry, calculus, and now biology. He is truly amazing. He should be the dean of MIT.
I like how you don't just pass on the material but also pass on the passion
6 years and this still save lives...
I wish everything good for you, you just saved my exam! Thank you!
Wonderful! I'm getting my TH-cam degree. I navigate from MIT to Harvard to UC Berkeley etc...all for free lol.
I wish this were around when I went to school. Thank you for the wonderful videos.
This was really helpful for my last minute exam preparations ❤️❤️❤️ If it wasn't for youtube, I would've failed my uni exams.
5:55-6:27 nothing you need to take notes on, but the reminder we all need! biology is amazing.
This was so helpful for my university genetics class! thank you!
Thank you for this. This was extremely helpful!
Mr. Khan, you seem like an awesome human being to me. I really wish you could coach me in person. I got only 16 days left before my 12th grade final examinations start. Thanks a lot for doing what you're doing. That's really great work. Keep it up. I will donate when I am able to. ❤❤
Me too as a fresh 12th grade student
His cousins actually prefer him in videos than him in person, maybe it's the system that allows him to be as good as a teacher he is today :)
I’m literally watching this before my exam please wish me luck
what did you get?
@@Star-pj8fz 34/50
I got a 75%. I hate biology 😂
God Is Great, May God Bless them all and you all and your families
Important to note that in eukaryotes the pre-mRNA processing occurs co-transcriptionally and not post-transcriptionally!
Thank you so much for this video!! You're the best! Your handwriting is nice and the way you explain it is so much more interesting. I always have more appreciation of what we're learning because of the way you teach it in these KA Videos.
Givee meee your handwriting 😻😻😻 and you actually have the capability of pinnng whatever you teach into my head!!
a whole lecture made ultra-clear in 10 minutes. thank you!!!
Thank you so much for the clear and "easy to understand" explanation.
This video is really helpful The way he teach is very understandable Thank you so much. It helped me a lot.
RIP for Medved's exam, but this video made it much easier. Thanks and keep it up bro!
Thank you for this tutorial...harpers is quite tedious to understand...this helps a lot
i don't know how many times throughout my biology career, I've had to rewatch this video
Thank you soo much that was an 1.30 h lecture of nonsense that u just turned into the most interesting and understandable information in 10.24 mins
This man is single-handedly carrying the US education system
Since this video has been uploaded one thing has been discovered. In termination, right after the hairpin is formed a bunch of Adenine's are present in the DNA, this makes it so that A lot Uracil's are transcribed. The bond between A en U (also T) is quite weak, with only 2 hydrogen bonds formed. So the pre-mRNA falls off.
2 yrs later i watch this once again! :))
Khan academy: You should be in AWE with this!!!
*Me: YAWNs
Biology: *am I a joke to you?
i rememver watching this in high school and now im in my gap years. and im. still watching this
I'm Korean university student. This explainment helps for Test. Thanks.
You should always remember that Biology is amazing. Yeah man it really is!!
thank you, khan academy, once again for saving my biology grade
love that my professor for my 400 level biochem class assigned us to watch this video
Hi Mr Khan, thanks for the explanantion but can you explain on the process on how the cap and tail is added and their purpose in conversion of pre mRNA to mRNA?
i learn more from sal than i do from my own professors
This is absolutely fascinating. Thanks for the great videos.
Allah who made this incredible staff..
honestly as a hon bio student you save my life thank you
This video is very well done. Thank you I understood everything. I'm 14 and you explained it very well. ❤
I love how you get excited about the material. Makes us students much more engaged and excited too. Endless thank yous Sal!!
sal always makes me feel safe lol
turns out helicases are involved in transcription after all
still a great video, keep up the good work Khan Academy, thanks!
With all these videos I don't think its necessary to go to school anymore
This dude seriously has a video for everything
you should upload more of DNA/RNA in depth processes!!
Love the enthusiasm!! Awesome video! The Audio kept cutting out about every minute or so on my end, not sure if it's just me or anyone else??
This recap is just what i needed!
You are very clear in your teaching Many thanks!
It is mentioned in this video that the RNA Polymerase is more than enough to open the DNA and begin transcription. However, in my Kaplan biochem 2020 MCAT prep booklet it says that RNA Pol II is preceded by helicases & topoisomerases to address unwinding/supercoiling. So both work?
I am so grateful for your videos! Thank you!
did you pre-draw all those shapes of ribosomes, DNA, and others?!?!?!?! that's insane
Thanks for the great explanation 🌹
Amazing sir and
made my day God bless you
You are the best teacher I have ever seen
''someone like me is going to give you these nice clean narrative'' is funny haha
wish you were my instructor... i love your facination for this.
I needed this exact video a year ago :'C
Hi, thank you for your hard work, it’s an amazing lesson! But I don’t quite understand the way mRNA develops towards 3’ instead 5’? Thanks
SUCH AN AMAZING VIDEO THANK YOU SO MUCH!!!!!
Thank you! That was super helpful and easy to digest!
So what's keep the Exons from floating away from each other once the introns are spliced?
5:28
The RNA being transcripted has the same sequence as the coding strand (with the Uracil replacing Thymine), BUT they don't have "the same information".
If the coding strand were being transcribed here, it'll give a different RNA sequence, therefore a different order of codons, which eventually gives different amino acids (different protein). So yeah, not the same information =)
thankyou soo much for the best explanation
Thanks.what is the primary,secondary,tertiary and quaternary structure of DNA??and how hydrogen bonds contributed in stability of DNA?l want answers please
at 5:19 why the T is replaced by U? I thought this happed in translation.
Umm no , I guess you are talking about the anti codon end of tRNA , in all types of RNA the Thymine is replaced with Uracil not only in tRNA but also in mRNA.
Nice. This makes so much sense now
Awesome video, in general awesome videos. I study Applied Biology and it's great to have your videos and from there read further into the subject. Thanks a lot! (also, this is great for getting an overview since I have no idea how to get all the biology stuff in my head I need to know in three days)
You’re amazing thank you teaching us all😁
THIS is what's helping me to keep up with my bio class 😂
Gona kill my bio final. Thanks for the videos bro they've helped me so much. Very confident I'm going to get the A I need in this course!
This guy is awesome...
Thanks ❤️
From 🇱🇰
thanks for helping on my Biology test!
hell yeah bro!
Thank you so much! I'm gonna shed a tear.
thanks for the video. it really helped me a lot understanding that
i have one question.. Is it the story about RNA polymerase(before story of introns and exons) for eucariotic cell and procariotic, or not?
you make mt life easy, stay blessed
thank you very much.it helped me a lot for my exam today
Sal Khan came to my school a few years ago... it was cool. Except I'm dumb and can't understand anything.
hi. just a question because i got confused. I am currently reading Harper's Medical Biochemistry. i usually watch your videos when i can't understand the book. According to Harper, the strand that is transcribed or copied into and RNA molecule is referred to as the template strand, and the other DNA strand, the non coding strand, is frequently referred to as the coding strand. I think you interchanged the terms in your video. Can you please clarify these things. Thank you so much!
That is exactly what he says in the video.
MAAAAAAAAAN love the way you teach!
Could you point out what MCAT stands for and what role it plays in this process?
M in 1st year medicine and m watching this coz it's very helpful 🤪😅🔥
Thanks a lot sir. It really helped me!
thanks for the video, such a very good video :))
but just realized that all cromosome or nucleus or enzyme or even protein picture we see in our textbooks or internet just an animation, so it's must be very very complicated in the real life. yet that's all are fascinating things to know about
Thanks a lot, that’s what I need ♥️♥️♥️♥️
Thanks khan on behalf of BD