Folate and Tetrahydrofolate Metabolism

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[@sharlasharla8701]

You saved my day, thanks! Just a question: I'm using Lehninger 7 ed. and at page 703, where there is a scheme of THF cycle like yours, I see that it say that the reaction N5-N10-Metylen-THF --> N5-N10-Methyl-THF needs NADPH and not NADH, so... I'am bit confused, can you help me?
thank you again!

[@adshehi99]

I think NADH is the right one!

[@Wolverchenus]

You saved me! Also you sound a bit like Korg from from Thor: Ragnarok but in a good way : )

[@wizardatmath]

Folate vs folinate?

[@Henipah]

Folinate is a synthetic analogue that mimics tetrahydrofolate i.e. the activated form and can bypass dihydrofolate reductase.