Hofmann Rearrangement and Curtius Reaction Mechanism - Primary Amides & Acid Chlorides to Amines

[@TheOrganicChemistryTutor]

Final Exams and Video Playlists: www.video-tutor.net/
Full-Length Math & Science Videos: www.patreon.com/mathsciencetutor/collections

[@alarcon9793]

so difficult to find a good explanation for the hoffman rearrangement, thank you so much!

[@salvadeng]

This man knows how to make things understandable. May God bless you!

[@ernestcheng1399]

You know these videos are great when you dont have sound and you still understand what is going on.

[@vnm5740]

26 minutes-totally worth it.tnx man.

[@amitdeshmukh1113]

26min 27 sec and a few Milli second which U tube doesn't cares about.

[@NikitkaDreamer]

i wanna cry
all this time i ignored Hoffman degradation and only thought about other ways to create primary amines, because of bromine
but if chlorine works too... damn

[@LordBrainz]

Actually, hypochlorite works as well

[@prof.husseinalhendawi6151]

It is really awesome. Thank you very much.

[@frodouardnambajimana4002]

That's extremely fascinating

[@michaelmiller8051]

I would really loved this more if it were in a playlist with all the other reactions

[@philipsoglo4143]

Great tutorial was really helpful thanks...

[@user-jd2lu1od6s]

thanks very much you are the best bro

[@neechan8348]

your lecture is very helpful for me ,thanks, sir

[@ayushanand5221]

Simp

[@user-pg3hw9qg8t]

so tricky! but you still nailed it!

[@leenImad]

And thank you so much but i deviced you to make it easier

[@efsunefsane1301]

Can you make a video about beckmann rearrangement to generate an epsilon-Caprolactam ? I wish you can read this message. 😊

[@neechan8348]

thanks .

[@ajithajith2314]

Very thanks bro.

[@monalisaarshnirvi2953]

Thank you sir. Your video was of great help to me.(:

[@Rudra-mm1qf]

thank you.

[@andreaxshadow4911]

Can NaOH give an hydrolysis resation with the amide, attacking the carbonyl group?

[@praharshinisai4944]

Thank u!!

[@ilimselyardm9698]

At the 21:53 why do we giving the partial positive oxygens hydrogen to another water molecule instead of partial negative oxygen (above the carbon) btw thank you sir for this good explanation Allah may bless you

[@iconicguy5717]

H2O generally attaches H to form H3O+ rather than attacking the partially negative oxygen to form the unstable products. Also, there will be repulsion between the oxygen of intermediate and oxygen's (of water) lone pairs.

[@sandy69402]

lmao u can't just randomly send a hydrogen atom through space like that except in cases like tautomerism or formation of zwitter ion

[@ilimselyardm9698]

@@sandy69402 Thank you

[@ilimselyardm9698]

@@iconicguy5717 Thank you

[@garrydhesi906]

Awesome

[@ajithajith2314]

Brother one doubt, please explain me difference between molecules and compounds.

[@saniyamulani3206]

When same atoms combined together it form molecules and when diff molecules comes together it form Compound

[@saniyamulani3206]

Same moles of atoms forms molecule

[@saniyamulani3206]

Diff molecule forms compound

[@shaikrafiq9498]

@@saniyamulani3206 yes

[@potumnn]

could hofmann rearrangement work also with secondary amines? to give us R-NH-R' ??

[@Yannickwhething]

No, it`s not simply not possible. Try the mechanism with a secondary amid, you should fail at the abstraction of the "second H-atom"/ the formation of the isocyante

[@Arjun-yz4sx]

why does alkyl rearrangement happens?

[@miroslavkaspar2246]

Its driven forward by CO2 formation, the CO2 leaves the reaction as a gas, thus forcing the reaction to competition.

[@ChemoSpecific]

If we treat N-methyl acetamide with Br2/NaOH, will we get N-Methyl methylamine

[@ChemoSpecific]

@Raj Kumar Answer is No

[@potumnn]

@@ChemoSpecific should we obtain dimethylamide?

[@lebogangmakhosi7637]

wow

[@hrishikeshdeore5340]

book name ?

[@ugh-ye3yc]

14:53

[@ajithajith2314]

Please reply me

[@leenImad]

But your videos are toooooooo long please make them shorter

[@philipsoglo4143]

Great tutorial was really helpful thanks...