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Well then say hello to Diabetes ..and hurting your liver ..and depleting methyl groups ..especially if you're an undermethylator. incredible to actually see someone recommend high dose niacin. wow ..what about the biomarker of your A1C ..and your Whole Blood Histamine ..from suppressing and almost turning off your methylation ..watch the video by Dr. Chris MasterJohn entitled ' Be careful with niacin
@@PrevMedHealth You mentioned in the video above you had other videos where you discussed your own Niacin selection in more detail. Would you provide a link or two?
I've been taking 500-1000 mg of niacin everyday for at least a decade, along with ester C, fish oil, ubiquinol, D3/K2 and magnesium. Despite the fact that cancer, heart disease and diabetes run deep in my family (both parents died at 73 from cancer and heart disease), I am in excellent health with zero signs of any chronic illness. I think niacin has a lot to do with it. I also do vigorous exercise at least 3 days per week, fast on a regular basis and I keep sugar/carbs to a minimum. I believe all of these things done together is the key to living a long healthy life.
@@judycrisenbery2982 The flush is mostly what is GOOD about it. I do nothing other than I bought a very low dose, 50mg. Still get some flush. I can increase from there. If you flush too much with 50, maybe cut it in half or thirds. I would not buy the 500mg they sell- no way. I think 50mg for me is fine- easy does things. It can be hard on liver I think if you go too high. Like most things- easy gets it done more safely.
Hello Dr Brewer, I am 52 years old I had a heart attack about 15 years ago I have three stents I do not take aspirin I do not take any statin drugs, and my cholesterol was extremely high about 2 years ago, as I started watching your channel I start taking niacin I take 2,000 mg in the morning 2,000 mg in the evening and within one year my cholesterol was as good as a teenager, without any change in diet. Thanks to your videos about niacin, so I'm a firm believer niacin works., I'm also a chef and as all cooks say when there's too many cooks in the kitchen, things never come out good, too many different medication too many different drugs will not get you the right result or at least a good result, that's what I think
Dr. Brewer. What a great video! You are taking healthcare and it’s management of to a higher ground. That Niacin study, they were right to cancel, based on not having a lifestyle contingent. I am learning so much from you in the management of my own 70% left carotid blockage. No smoking gun for me and at 54yrs I was as surprised as you to hear of my situation. Thank you, thank you for all your help. Keep those outstanding videos coming.
I have a problem with insulin resistance. I was doing pretty good with diet. My LDL was a little high so I started taking Niacin 500mg. LDL went way down. My glucose levels started going up. I didn't connect the dots until I saw a report that Niacin can cause insulin resistance to increase. I stopped Niacin and now glucose is very good again.
I love the flush!!! I was prescribed niacin for low HDL years ago......it worked!! A couple of years ago I quit because I went from High risk to low risk in regards to my cholesterol because.............I was consuming so many omega 3's...........as well as a healthy low carb diet with a few root beer floats intermittently! So mu,ch for the NIH, FDA, USDA, ADA, AHA, and all the rest of the establishment!!! I think I will resume taking niacin because I miss the flush!!! It made me feel alive and kicking!!!
If your doc said your Cholesterol marker was high risk, I think you need to change doctor.. What matters is your Triglyceride levels, you want these to be somewhat in the low end.
I also use niacin. I'm 71, take about a gram a day and it warms my skin. From what I've read and heard it help. A few years a go there was a doctor who was 95 at the time. I cant remember if he studied niacin or if he took it for a long time. Forgot his name. But that was when I started taking it on and off. I take no drugs and never have. I try to cure the cause instead of taking a drug to comer the cause. I believe exercise helps improve health.
I've been on 1500-2000 MG for at least 3 years. I was getting rashes whenever I went from 1500 to 2000 but I guess ive adjusted. My cardiologist recommended I not take it but it's inexpensive and doesn't appear to be harming me so I'll continue to take it.
Have you tested your homocysteine? According to articles and studies I read on NIH site, Niacin causes hyperhomocysteineaemia. I was taking 1g/day and the last time I tested my homocysteine it was high and it made me very disappointed.
@@jerseyjim9092 mine was 40 when I was taking 1g of Niacin per day. I reduced the dose to 500mg/day and it went down to 14. I was also taking B complex and methylfolate at times since it said it can help lower it quickly. I'm not sure if it did but reducing Niacin dose had a considerable effect on homocysteine.
I am like most people can't Tolerate niacin at the therapeutic doses. I can name many other things like Aged garlic extract that has reduced coronary plaque and heart attack and stroke. It also helps with cancer. Tocotrienols and Gilsodin also have impressive results. I do agree simply eat better is vital. The people living in Italy, and some other countries, have shown us how to eat, and how to live for longevity.
I use it for Triglycerides and LP (a) but after watching Dr. Brad Stanfields video on the proof how it increases NAD+ levels and research papers, I am convinced to not drop it.
Been taking atleast 500 mg niacin (full flush) and 500 vitamin C for more than 10 years. 66 years old at this time, credit niacin for ideal bloodwork, blood pressure, receding gumline reversed and other benefits. I avoid taking niacin together with other meds as a matter of caution.
Dr. Brewer, thank you for all your valuable information. My doctor is insisting that I take cholesterol medication. My trig 97/hdl 70 ratio is 1.38. I will have labs redone in 3 months but in the meantime I have started taking niacin. I eat a very low carb diet. Anyway, thank you for all your wonderful, educational videos.
@dereksdiatribe I went to my primary care physician in October 2022 because I have Hashimotos and hypothyroidism. She told me to find another doctor because I still refused to take statins. She also did not send an Rx for my thyroid. I do not have a primary care physician now.
Note the new mega interest over NMN, and or NR. Niacin increases NAD+, and they have yet to do a niacin vs NMN or NR (both metabolites of niacin...), likley because niacin is FAR less $. Much of the benefits from niacin likley its impact on NAD+.
Current NICE guidelines in the UK explicitly say NOT to offer Niacin B3 to patients with low HDL. Primary health care Doctors (GPs) are being instructed by the NHS “best practice” guidelines. What is more interesting no supporting evidence is provided with this apart from the standard “no good evidence” However those same practitioners remain keen to prescribe statins without testing lipid levels. The NICE guidelines instructions are to lower “X LDL” by 40%. No optimum numbers are provided or supporting references. Statin doses should be increased until frank signs of damage become apparent or that “40% reduction” has been achieved.
Niacin was one of the first treatments prescribed to lower LDL or “bad” cholesterol. However, eventually niacin showed to be less effective than other cholesterol-lowering drugs and was associated with other negative effects and higher mortality rates in previous research.
Taking Niacin for skin conditions I look forward too skin flushing to transport cinnamon plant oils to into my skin low dose works great dose is 200 mg daily. It also keeps blood levels perfect.
I just got it. Staring off at only 50 seems comfortable to me. I might increase over time. I can still feel some flush but it is not bothersome. If THEY tell you not to take it, it is often good for you.
Excellent , thanks so much for your expert opinion . The WEBINAR looks like what we have been looking for ! Our GP doesn't have a clue . When we ask for more detailed blood work or Calcium scans he says just take the statins . Thanks again for the cutting edge information . Max
I live on the road and A LOT of places do not even test for the advanced lipid panel with the particulate count. Very frustrating, I had to demand the GP give me a referral for the test and I’m still in the process of finding a place and scheduling it.
Harvard study was refined carbs, not whole grains and complex carbs. Please clarify that in your video. It was seen at 7:10 on your video "a diet high in refined carbohydrates (white bread, sugars, etc).....That is not the Harvard School of Public Health Healthy Eating food plate of 2011. Always avoid refined carbs, as in bagels, donut, cereals. Ezekiel bread and whole wheat pasta, bring it on.
Dr . Kahn, isn’t the issue any processed food in general? The standard American diet should be put on trial for murder! There ain’t nothing healthy about consuming dessert all day! You can’t separate refined carbs from whole grains and complex carbs in today’s world. It’s all adulterated and detrimental to our health . We are told to follow the food pyramid and we’ve blindly done it. Now heart disease, hypertension,diabetes & obesity plaque or nation. We blame it on salt. We all know it’s sugar, all 61 hidden names for it, from maltodextrin to sucralose.The food pyramid has us comfortably eating sugar all day and the medical field hands out a pill to circumvent that. No I don’t think he should clarify, he was quite clear, if you purchase food out of a box it should not be labeled food. It has no nutritional value. Save for fresh vegetables there is no safe carbohydrate. If I am missing the mark please break it down in layman’s terms.
I'm been taking Niacin When I Had Chest pain Are high Blood Pressure. Clear my eyes 2020 vision, no more glasses. No more Dizziness No more, hi, cholestero. I believe if someone had a stroke, they can take it unblock the smallest veins in your head, eyes face
I don’t take statins anymore, my HDL got up to 77 12 months ago. But for some reason my labs I just had my HDL fell to 55. In addition I thought Niacin was bad for your liver so I stopped taking it 2 years ago
@@boomerang0101 any supplement that is described as slow, sustained, extended, delayed or whatever other synonym are slowing the absorption of that nutrient which lengthens the time that the liver is exposed to such a high dose. That is what creates the potential for issues. Look up Dr. Andrew Saul for a good source of info for niacin supplementation.
Thanks doctor. I am 55, on a statin and BP medication (lisinopryl and amlodipine). Obese. My blood pressure is well under control. Just stated taking "real" niacin that causes flushing. I kinda like the feeling. However, I am wondering if I should lower the statin? I feel great, sleep great, but too many carbs ("American diet" as my physician calls it). Started lifting again, steam room, lots of water and sunshine. Trying to lose belly/butt fat.
Are we talking process carbs or any carbs? Because it’s my understanding that whole plant carbs are not harmful. I eat lots. Tons of energy, kept 65 pounds off for seven years now and exercise like a Tyrannosaurus rex.
Does nicotinamide riboside have similar lipid benefits to nictonic acid? Your PrevMed site is wonderful! Do you have a keto cookbook? I'll look again, but I recall a sardine breakfast recipe that sounds delicious! I wonder if it would be as good with mackerel?
Thank you for posting this video. i have been taking 1500mg niacin for over 10 years now. Read Niacin: The Real Story and done lots of research. If i hadn't done that I would have been conviced by the meta analysis you find when you google niacin research and not taken it. But I knew better and was shocked by the "research". Then found your video and it cleared everything up immediately. I greatly appreciate what you are doing!
I asked my doc about niacin when he was recording "the patient refused medical intervention for high cholesterol ". He said we no longer recommend it. No straight answer as to why.😊
My Doctor basically said the same thing. He told me that all the exercise and natural supplements would not do anything for my heart disease. High cholesterol, and other high lipid tests. He said he would not be monitoring me because I refused ”Western medicine”
How bad are the hot flushes? I get enough from menopause, I’m a bit cautious in taking niacin because of that? Any ladies out there that have been through this & can address this?
Thank you. I been taking niacin over a decade. I take it for Lpa, cholesterol. I buy it in bulk because the prepackaged niacin has too much filler. Taking it for so long don't really notice flush anymore. It really works. But should monitor ast/alt and that can be done by going to Quest lab. Don't need a prescription to self monitor. 🙏🤗
@@marcrabbat yes. I noticed that after starting treatment my Quest Diagnostic test showed 18! Previously it was significantly lower. Now within past year it went lower to @ 12 or 14. I would make appointment but my new car has not arrived. I been waiting for my car approximately 4months. Have not had problem with homocystine when taking niacin.
Enduricin was also my choice of "traditional" niacin. Thank you! Is there any downside, other than cost, that you're aware of to nicotinamide rhiboside? Again, thank you!
My triglyceride level is too high 1133 😢 ordered vitamin b3 500mg, as usual as I used it last time I became red spots on my skin as I googled which normal, cinnamon helps me a lot.
I have been taking Niacin for 2 years and it works for my HDL/LDL/TRIG. My doctor put me on statins, that didn't work to lower my levels and I heard about Niacin, so I gave it a try and am so glad I did. I have a question. I love grapefruit and am wondering is it ok to eat them while taking Niacin?
depecheddurand I’ve done that before as well and still get an awful flush. Even 30mgs makes me feel like I’m about to set ablaze and have a heart attack.
Take an asprin or ibuprofen about 20 minutes prior to taking the niacin. The flush will be very reduced. Then you can lower the dose of the NSAID and slowly increase the niacin dose. I'm speaking from my own experiences. Check with doctor first.
If Niacin increase HDL and reduces Triglycerides, what is its effect on insulin resistance? I have seen in a video Niacin improving Metabolism in the Mitochondria. Any research?
I took 500mg niacin B3 and gave it to my husband. Oh LORD!! I thought we need to go to ER… It was like sunburn on steroids! It was even hard to breathe… Plus dizziness…After doing quick research and realizing what’s happening, we just waited for about 2 hours and it gradually went away. I’m afraid to take it again. What’s your suggestion? Take 100mg to start with and gradually increase or what? Thanks
Be careful with that, it is a different formulation. I was educated about that at the vitamin dept at a small local organic grocer. I totally trust those vitamin dudes.
@@bradbennett8716 thanks for the tip. What I initially read at consumerlabs.com made it sound like a good alternative. Quote: "inositol hexanicotinate may provide the best of both worlds in that it may reduce cholesterol levels and cause less flushing". I will look into this further.
Thank you for clarifying. I love this video. My wife and I are stopping per our doctor statins and we are switching to the extended release 500 mg pharmaceutical niacin. My question to you doctor since you take niacin have you ever experienced high blood sugar levels
Dr Brewer thank you for your wonderfully educational videos. I have CVD on 80mg statin. What dosage do you recommend Niacin.I am trying to reduce my LDL number of particles. Thank you Laird
Thanks. The standard dose of niacin is 2 grams. But when you use CV inflammation testing, you get a different picture. Also, until you fully understand your carb metabolism through OGTT, Kraft & CGM - you really don’t understand your risk factors. .
@@PrevMedHealth I am grateful your replied thank you. I dont want to over do my turn but please just this one last f/u question My Primary wants me on 500mg Niavase My LDL is 55 Triglicerides 77 but have 1239 small LDL particles and high Lipoprotien. Is this a death sentence or should I be worried. if I am Eating whole base plant diet, exercising the whole healthy routine, no smoking 3 wines a week and I let the women chase me ha
@@contemporaryclassicalguita8355get off the plant based diet... You need the fats especially animal fats as they help reigate everything, we have been lied to about saturated fats and coronary heart disease new studies prove this what I'm saying is correct
Tom dayspring on Peter attia’s podcast mentioned that sure niacin improves all those markers but at the end of the day it does not “work” because it actually worsens all cause mortality slightly. So his conclusion is that it must be doing something “bad” that we don’t understand. So it works for the markers but isn’t working….
Will or can Niacin raise your blood sugar? My not so scientific test “seems” like my fasting blood sugar is up slightly on my insulin resistance self when taking Niacin. I “was” pre-diabetic before a low carb diet and losing 30 lbs (20 more lbs to go) and my fasting blood sugar unfortunately still hovers around 95-100 (which I am working on with fasting/intermittent fasting currently) so when my last fasting sugar was solidly past 100 with the “only” known change in diet was Niacin made me ask the question? Any one else experience this? Thanks in advance.
Yes. This effect tends to decrease over a few months. For those who take statins, they can as well. But with statins, it’s permanent. Pitavastatin is the exception.
I took 2 g per day for 5+ years and recently stopped due to causing LPB and insulin resistance. I don't know if I resume and stay at lower dosage, there would be any benefits or not. Not much research info since there is NO profitable market for it.
Hi , ive been taking Niacin for over 10 years 3 grams a day , I'm thinking of including Crestor 2.5 mg 3 times a week , any thoughts on this ? I also take K2 Mk7 , D3 and a fish oil supplement.
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My doctor took me off niacin because of the AIm-High report. I would like to go back on niacin ,what should I say to my doctor or should I just take OTC niacin???
Hi Doctor .delighted to come across your vid on you tube .I didn’t know there was still this interest in Niacin . Am I ok using Niacinamide instead ? To avoid the flush . Age 74 , overweight .
Please do a web search on this paper, "New Perspectives on the Use of Niacin in the Treatment of Lipid Disorders" published in 2014. In the paper, Figure 1 has the dosing info. Table 2 has the recommendations on how to reduce flushing.
The Aim High trial was a bust study. Niaspan (b3)was one of the best products on the market . Post AH trial, many cards and endos walked away from it. What an absolute sad story.
Hey doc I currently take flush free niacin I am confused should I continue this or go straight to the niacin and start with low levels of niacin and work my way up thank you
@@lindaedvardsson4218 Try this book, cheap via Kindle, very detailed: www.amazon.com/Niacin-Story-Wonderful-Healing-Properties/dp/1591202752 Helped me a lot do decide which and how much to take.
acjitsu Has eaten it before but.. If he had a approx. dosage to take this daily.. for Lyme.. espec. Bartonella.. Do you know?!..🥺💚.. Thank you for answering❣️.. I have to look up all my self due to living in sweden.. I has no doctor that could check me every sec week or so..😣.. 💚❣️
High dose niacin is hard on the liver. It also robs the body of methyl groups. I won't use amounts that are far out of line with the RDA I have very low Lp(a) without niacin.
Thank you for your video, but I have one question. I take Non-flush Niacin, isn't that just as good as Niacin that causes flush? Thank you for your reply.
I have just started taking niacin 500mg the flush is severe at the moment but my body will get used to it I intend increasing my dose I am taking it for tiredness and my skin.
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Took niacin, don't smoke, don't drink, was on a low carb diet, went to the gym fairly regularly. One day, I went to the gym, pushed the sled across the floor about 6 times, had a heart attack. I know that my inflammation is high, but I can't get the doctors to treat that, they just want to push the statins. I had a bad reaction to statins, injuries weren't healing, aches pains, brain fog, depression... Now they have me on ezetimibe, I guess we'll see how this goes. I need to know what the protocol is. Is it a gram twice a day, or once, or can I split a gram between morning and night?
weird, do you take k2 to get the calcium out of your bloodvessels and into your bones? NMN or NR can be a better alternative to Niacin, though more expensive, they are much more effective
![Niacin (Vitamin B3): Flushing Away Heart Disease. [4 Studies]](/img/n.gif)
What brand type and dosage should I being looking at
Enduracin or Rugby. Start at 250. Ramp up until you get improvement in cv inflammation & other biomarkers.
Well then say hello to Diabetes ..and hurting your liver ..and depleting methyl groups ..especially if you're an undermethylator. incredible to actually see someone recommend high dose niacin. wow ..what about the biomarker of your A1C ..and your Whole Blood Histamine ..from suppressing and almost turning off your methylation ..watch the video by Dr. Chris MasterJohn entitled ' Be careful with niacin
@@PrevMedHealth You mentioned in the video above you had other videos where you discussed your own Niacin selection in more detail. Would you provide a link or two?
I've been taking 500-1000 mg of niacin everyday for at least a decade, along with ester C, fish oil, ubiquinol, D3/K2 and magnesium. Despite the fact that cancer, heart disease and diabetes run deep in my family (both parents died at 73 from cancer and heart disease), I am in excellent health with zero signs of any chronic illness. I think niacin has a lot to do with it. I also do vigorous exercise at least 3 days per week, fast on a regular basis and I keep sugar/carbs to a minimum. I believe all of these things done together is the key to living a long healthy life.
Good job!
What do you do to prevent flushing?
@@judycrisenbery2982 The flush is mostly what is GOOD about it. I do nothing other than I bought a very low dose, 50mg. Still get some flush. I can increase from there. If you flush too much with 50, maybe cut it in half or thirds. I would not buy the 500mg they sell- no way. I think 50mg for me is fine- easy does things. It can be hard on liver I think if you go too high. Like most things- easy gets it done more safely.
@@MOAB-UT thank you for your help:-))
@@judycrisenbery2982 You are very welcome my friend Judy.
Yours- in health- Namaste.
I started taking a mere 100mg niacin 2 times times daily and this small dose has ended my binge eating. This has been a miracle for me.
How?
Did you have the flushing with 100mg… kinda scary reading about the flushing aspect? 🤷🏼♀️
@@mountaingirl1797 I love the flushing. Whats wrong with it, other than being Red and tingly?
There is no danger, it is normal. With 100mg, I doupt it. @@mountaingirl1797
Hello Dr Brewer, I am 52 years old I had a heart attack about 15 years ago I have three stents I do not take aspirin I do not take any statin drugs, and my cholesterol was extremely high about 2 years ago, as I started watching your channel I start taking niacin I take 2,000 mg in the morning 2,000 mg in the evening and within one year my cholesterol was as good as a teenager, without any change in diet. Thanks to your videos about niacin, so I'm a firm believer niacin works., I'm also a chef and as all cooks say when there's too many cooks in the kitchen, things never come out good, too many different medication too many different drugs will not get you the right result or at least a good result, that's what I think
Do you take the regular niacin that flushes
Thank you
Thanks for sharing
Yes I do take regular niacin and I used to have flushes the first two weeks but nothing after that
@@sdbrickoven You are _'Niacin Man ' ..!_ 😉´´
Hello, Mr. Ali torabi
can you please write about your blood sugar, is it okay?
Niacin causes namly diabetes?
Thank you
Ive been on good diet , exercise daily, no alcohol, no smoking, sleep 7+ hrs,D3+K2, fish oil etc and my HDL jumped from
Dr. Brewer. What a great video! You are taking healthcare and it’s management of to a higher ground. That Niacin study, they were right to cancel, based on not having a lifestyle contingent. I am learning so much from you in the management of my own 70% left carotid blockage. No smoking gun for me and at 54yrs I was as surprised as you to hear of my situation. Thank you, thank you for all your help. Keep those outstanding videos coming.
Thank you very much!!
Can u give us an update?
I have a problem with insulin resistance. I was doing pretty good with diet. My LDL was a little high so I started taking Niacin 500mg. LDL went way down. My glucose levels started going up. I didn't connect the dots until I saw a report that Niacin can cause insulin resistance to increase. I stopped Niacin and now glucose is very good again.
I love the flush!!! I was prescribed niacin for low HDL years ago......it worked!! A couple of years ago I quit because I went from High risk to low risk in regards to my cholesterol because.............I was consuming so many omega 3's...........as well as a healthy low carb diet with a few root beer floats intermittently! So mu,ch for the NIH, FDA, USDA, ADA, AHA, and all the rest of the establishment!!!
I think I will resume taking niacin because I miss the flush!!! It made me feel alive and kicking!!!
Thanks for sharing
Fair play to you . As another old geezer the flush scared the bejaysus out of me . . I now take Niacinamide 2000-3000 a day
They say niacinide doesn't have the health benefits that niacin does
@@davidmurphy4676 the flush is healthy for you, not dangerous at all.. Niacinamide is bad for your liver, go back to Nicotinic Acid.
If your doc said your Cholesterol marker was high risk, I think you need to change doctor.. What matters is your Triglyceride levels, you want these to be somewhat in the low end.
I also use niacin. I'm 71, take about a gram a day and it warms my skin. From what I've read and heard it help. A few years a go there was a doctor who was 95 at the time. I cant remember if he studied niacin or if he took it for a long time. Forgot his name. But that was when I started taking it on and off. I take no drugs and never have. I try to cure the cause instead of taking a drug to comer the cause. I believe exercise helps improve health.
Routine fasting is also a great way to boost overall health and longevity.
Abram Hofffer
Dr. Brewer, Thank you for UNTANGLING the conflicting information as you many times do for us.
I've been on 1500-2000 MG for at least 3 years. I was getting rashes whenever I went from 1500 to 2000 but I guess ive adjusted. My cardiologist recommended I not take it but it's inexpensive and doesn't appear to be harming me so I'll continue to take it.
Are you still taking it? I took 2 g per day for 5+ years and I stopped recently due to fear of insulin resistance warnings.
@@nextime3927 Yes, 1500mg with no issues. As I recall from another video, Dr Brewer indicated any increase in blood glucose is temporary.
Have you tested your homocysteine? According to articles and studies I read on NIH site, Niacin causes hyperhomocysteineaemia. I was taking 1g/day and the last time I tested my homocysteine it was high and it made me very disappointed.
@@marcrabbat I had it checked in Aug of 2019 and it was 9 which they said was optimal. But at that time I was only taking 500mg of Niacin.
@@jerseyjim9092 mine was 40 when I was taking 1g of Niacin per day. I reduced the dose to 500mg/day and it went down to 14. I was also taking B complex and methylfolate at times since it said it can help lower it quickly. I'm not sure if it did but reducing Niacin dose had a considerable effect on homocysteine.
I am like most people can't Tolerate niacin at the therapeutic doses. I can name many other things like Aged garlic extract that has reduced coronary plaque and heart attack and stroke. It also helps with cancer. Tocotrienols and Gilsodin also have impressive results. I do agree simply eat better is vital. The people living in Italy, and some other countries, have shown us how to eat, and how to live for longevity.
I use it for Triglycerides and LP (a) but after watching Dr. Brad Stanfields video on the proof how it increases NAD+ levels and research papers, I am convinced to not drop it.
Can I ask how much you use and the impact it had on lp (a) ?
On a later video, Dr. Stanfield recommends taking TMG to fix the methylation issues caused by niacin.
@@papias133 cuz the homocysteine levels raise,and along with cardiovascular issues risk.
Been taking atleast 500 mg niacin (full flush) and 500 vitamin C for more than 10 years. 66 years old at this time, credit niacin for ideal bloodwork, blood pressure, receding gumline reversed and other benefits. I avoid taking niacin together with other meds as a matter of caution.
Dr. Brewer, thank you for all your valuable information. My doctor is insisting that I take cholesterol medication. My trig 97/hdl 70 ratio is 1.38. I will have labs redone in 3 months but in the meantime I have started taking niacin. I eat a very low carb diet. Anyway, thank you for all your wonderful, educational videos.
You are very welcome.
@dereksdiatribe I went to my primary care physician in October 2022 because I have Hashimotos and hypothyroidism. She told me to find another doctor because I still refused to take statins. She also did not send an Rx for my thyroid. I do not have a primary care physician now.
@dereksdiatribe I haven't had it checked again.
Note the new mega interest over NMN, and or NR. Niacin increases NAD+, and they have yet to do a niacin vs NMN or NR (both metabolites of niacin...), likley because niacin is FAR less $. Much of the benefits from niacin likley its impact on NAD+.
Thanks much for this video, Sadly those who talk negatively about it didn't analyze the studies like you did.
Thank you very much!
Current NICE guidelines in the UK explicitly say NOT to offer Niacin B3 to patients with low HDL. Primary health care Doctors (GPs) are being instructed by the NHS “best practice” guidelines. What is more interesting no supporting evidence is provided with this apart from the standard “no good evidence” However those same practitioners remain keen to prescribe statins without testing lipid levels. The NICE guidelines instructions are to lower “X LDL” by 40%. No optimum numbers are provided or supporting references. Statin doses should be increased until frank signs of damage become apparent or that “40% reduction” has been achieved.
Thanks for sharing.
Niacin was one of the first treatments prescribed to lower LDL or “bad” cholesterol. However, eventually niacin showed to be less effective than other cholesterol-lowering drugs and was associated with other negative effects and higher mortality rates in previous research.
Taking Niacin for skin conditions I look forward too skin flushing to transport cinnamon plant oils to into my skin low dose works great dose is 200 mg daily. It also keeps blood levels perfect.
I just got it. Staring off at only 50 seems comfortable to me. I might increase over time. I can still feel some flush but it is not bothersome. If THEY tell you not to take it, it is often good for you.
Try am extended release! Designs for health makes a 500mg CRT
Doctor wanted me on a statin drug....FORGET THAT!!!
I TAKE 2000 MG NIACIN.....
LOVE THE FLUSH!!!
Nice job Brewer. I use Niacin widely and it is crucial for many as you know. I try not to use it with statins.
if someone is on a Monday Wednesday Friday statin schedule, can you factor in niacin on those off days?
Thanks, Dr K. Good to hear from you.
Excellent , thanks so much for your expert opinion . The WEBINAR looks like what we have been looking for ! Our GP doesn't have a clue . When we ask for more detailed blood work or
Calcium scans he says just take the statins . Thanks again for the cutting edge information .
Max
Thanks.
Time to get a new GP…
thank you for sharing this information Dr. 🙂
Thanks
Ron Krauss MD states “ the perfect patient for niacin: a person with high lp (a) and high small ldl particle counts.”
Those are 2 very common indications for it.
I live on the road and A LOT of places do not even test for the advanced lipid panel with the particulate count. Very frustrating, I had to demand the GP give me a referral for the test and I’m still in the process of finding a place and scheduling it.
Thanks for the reinforcement Doc
Thanks
Harvard study was refined carbs, not whole grains and complex carbs. Please clarify that in your video. It was seen at 7:10 on your video "a diet high in refined carbohydrates (white bread, sugars, etc).....That is not the Harvard School of Public Health Healthy Eating food plate of 2011. Always avoid refined carbs, as in bagels, donut, cereals. Ezekiel bread and whole wheat pasta, bring it on.
Dr . Kahn, isn’t the issue any processed food in general? The standard American diet should be put on trial for murder! There ain’t nothing healthy about consuming dessert all day! You can’t separate refined carbs from whole grains and complex carbs in today’s world. It’s all adulterated and detrimental to our health . We are told to follow the food pyramid and we’ve blindly done it. Now heart disease, hypertension,diabetes & obesity plaque or nation. We blame it on salt. We all know it’s sugar, all 61 hidden names for it, from maltodextrin to sucralose.The food pyramid has us comfortably eating sugar all day and the medical field hands out a pill to circumvent that. No I don’t think he should clarify, he was quite clear, if you purchase food out of a box it should not be labeled food. It has no nutritional value. Save for fresh vegetables there is no safe carbohydrate. If I am missing the mark please break it down in layman’s terms.
@@umayaswellcallmejesus1489 - Absolutely true. Thanks for spelling it all out.
I'm been taking Niacin When I Had Chest pain Are high Blood Pressure. Clear my eyes 2020 vision, no more glasses. No more Dizziness No more, hi, cholestero. I believe if someone had a stroke, they can take it unblock the smallest veins in your head, eyes face
I don’t take statins anymore, my HDL got up to 77 12 months ago. But for some reason my labs I just had my HDL fell to 55. In addition I thought Niacin was bad for your liver so I stopped taking it 2 years ago
Only the "slow" or "sustained" release types are bad for the liver. Niacin in the form of nicotinic acid is just fine.
@@theeternalonecorrect. But what about the extended release types?
@@boomerang0101 same thing, just a different description.
@@theeternalone what do u mean
@@boomerang0101 any supplement that is described as slow, sustained, extended, delayed or whatever other synonym are slowing the absorption of that nutrient which lengthens the time that the liver is exposed to such a high dose. That is what creates the potential for issues. Look up Dr. Andrew Saul for a good source of info for niacin supplementation.
Nice video Doc, keep up the great work you are doing.
Thanks
Thanks doctor. I am 55, on a statin and BP medication (lisinopryl and amlodipine). Obese. My blood pressure is well under control. Just stated taking "real" niacin that causes flushing. I kinda like the feeling. However, I am wondering if I should lower the statin? I feel great, sleep great, but too many carbs ("American diet" as my physician calls it). Started lifting again, steam room, lots of water and sunshine. Trying to lose belly/butt fat.
Thank you very much for the wonderful and helpful videos
Thanks.
Are we talking process carbs or any carbs? Because it’s my understanding that whole plant carbs are not harmful. I eat lots. Tons of energy, kept 65 pounds off for seven years now and exercise like a Tyrannosaurus rex.
My HDL is 72, my triglycerides are 97, and VLDL is 14, why is my doctor recommding that I take a statin. Please help. I'm very keto.
Doc what about niacin raising blood sugar leading to diabetes?
Does nicotinamide riboside have similar lipid benefits to nictonic acid? Your PrevMed site is wonderful! Do you have a keto cookbook? I'll look again, but I recall a sardine breakfast recipe that sounds delicious! I wonder if it would be as good with mackerel?
Thank you for posting this video. i have been taking 1500mg niacin for over 10 years now. Read Niacin: The Real Story and done lots of research. If i hadn't done that I would have been conviced by the meta analysis you find when you google niacin research and not taken it. But I knew better and was shocked by the "research". Then found your video and it cleared everything up immediately. I greatly appreciate what you are doing!
I've heard high doses can cause liver damage. Seems that's not true??
What about niacin for skin cancer ? Will it raise blood glucose ?
I asked my doc about niacin when he was recording "the patient refused medical intervention for high cholesterol ". He said we no longer recommend it. No straight answer as to why.😊
My Doctor basically said the same thing. He told me that all the exercise and natural supplements would not do anything for my heart disease. High cholesterol, and other high lipid tests. He said he would not be monitoring me because I refused ”Western medicine”
@@SilverLady61 I'm lucky. I can't be kicked out of VA med care.
@@curiouskitten if you have other conditions such as diabetes you should not take niacin.
How bad are the hot flushes? I get enough from menopause, I’m a bit cautious in taking niacin because of that?
Any ladies out there that have been through this & can address this?
That's why I dont take niacin, but I read that 35 mg theres no flushing
6:00 i agree. its too high dose. i was wondering before if a lower dose will reduce the flushing.
They say no more than 35 mg & tgere should be no flushing
Excellent...!!!
Thank you. I been taking niacin over a decade. I take it for Lpa, cholesterol. I buy it in bulk because the prepackaged niacin has too much filler. Taking it for so long don't really notice flush anymore. It really works. But should monitor ast/alt and that can be done by going to Quest lab. Don't need a prescription to self monitor. 🙏🤗
Thanks
Have you ever tested your homocysteine? According to studies, it causes hyperhomocysteineaemia.
@@marcrabbat yes. I noticed that after starting treatment my Quest Diagnostic test showed 18! Previously it was significantly lower. Now within past year it went lower to @ 12 or 14. I would make appointment but my new car has not arrived. I been waiting for my car approximately 4months. Have not had problem with homocystine when taking niacin.
@@debstayblessed9549 u can do phone appts these days...can i ask ...where do u get your bulk niacin
Enduricin was also my choice of "traditional" niacin. Thank you! Is there any downside, other than cost, that you're aware of to nicotinamide rhiboside? Again, thank you!
This is a good update, but still 3 years old now. www.ncbi.nlm.nih.gov/pmc/articles/PMC7352172/
My triglyceride level is too high 1133 😢 ordered vitamin b3 500mg, as usual as I used it last time I became red spots on my skin as I googled which normal, cinnamon helps me a lot.
I started _SloNiacin_ twice a day. Wish me luck 👍
Thanks
Niacin is awesome.
Thanks
I have been taking Niacin for 2 years and it works for my HDL/LDL/TRIG. My doctor put me on statins, that didn't work to lower my levels and I heard about Niacin, so I gave it a try and am so glad I did. I have a question. I love grapefruit and am wondering is it ok to eat them while taking Niacin?
Good question, I wonder the same. Wish Dr. B would clarify that for us.
Statins require more medical "services" and appointments.
Good point.
I can’t even use the smallest amount of niacin without a horrific flush. It’s so bad it’s painful.
take after eating full diet not on empty stomach i went through hell and next day i ate it after lunch and i was fine.
depecheddurand I’ve done that before as well and still get an awful flush. Even 30mgs makes me feel like I’m about to set ablaze and have a heart attack.
Take an asprin or ibuprofen about 20 minutes prior to taking the niacin. The flush will be very reduced. Then you can lower the dose of the NSAID and slowly increase the niacin dose. I'm speaking from my own experiences. Check with doctor first.
If Niacin increase HDL and reduces Triglycerides, what is its effect on insulin resistance? I have seen in a video Niacin improving Metabolism in the Mitochondria. Any research?
How much Niacin do you recommend or take
I took 500mg niacin B3 and gave it to my husband. Oh LORD!! I thought we need to go to ER… It was like sunburn on steroids! It was even hard to breathe… Plus dizziness…After doing quick research and realizing what’s happening, we just waited for about 2 hours and it gradually went away.
I’m afraid to take it again.
What’s your suggestion? Take 100mg to start with and gradually increase or what? Thanks
Thanks. Take much lower doses as trials. Also take slow-down versions, such as Rugby or Enduracin. Most of our patients tolerate Enduracin better.
It's all about the money. I purchased no flush Niacin. Another example is hydroxychloriquine vs remdesiver. Cheap vs extremely expensive.
Be careful with that, it is a different formulation. I was educated about that at the vitamin dept at a small local organic grocer. I totally trust those vitamin dudes.
@@bradbennett8716 thanks for the tip. What I initially read at consumerlabs.com made it sound like a good alternative. Quote: "inositol hexanicotinate may provide the best of both worlds in that it may reduce cholesterol levels and cause less flushing". I will look into this further.
@@bradbennett8716 The "no flush" "slow release" type of niacin has the potential to cause liver issues. Just stick with straight nicotinic acid.
Thank you for clarifying. I love this video. My wife and I are stopping per our doctor statins and we are switching to the extended release 500 mg pharmaceutical niacin. My question to you doctor since you take niacin have you ever experienced high blood sugar levels
Timed release doesn't work as well. 500mg flush niacin three times a day
niacin gives me an irregular heartbeat
This is an old video. He is not taking niacin no longer. That he has said in another video.
Dr Brewer thank you for your wonderfully educational videos. I have CVD on 80mg statin. What dosage do you recommend Niacin.I am trying to reduce my LDL number of particles. Thank you Laird
Thanks. The standard dose of niacin is 2 grams. But when you use CV inflammation testing, you get a different picture. Also, until you fully understand your carb metabolism through OGTT, Kraft & CGM - you really don’t understand your risk factors. .
@@PrevMedHealth I am grateful your replied thank you. I dont want to over do my turn but please just this one last f/u question My Primary wants me on 500mg Niavase My LDL is 55 Triglicerides 77 but have 1239 small LDL particles and high Lipoprotien. Is this a death sentence or should I be worried. if I am Eating whole base plant diet, exercising the whole healthy routine, no smoking 3 wines a week and I let the women chase me ha
@@contemporaryclassicalguita8355 I don't believe one should take both statins and niacin at the time.
@@contemporaryclassicalguita8355get off the plant based diet... You need the fats especially animal fats as they help reigate everything, we have been lied to about saturated fats and coronary heart disease new studies prove this what I'm saying is correct
Should a person consume flushing niacin or non-flushing?
Do you have a video on berberine ? What is your opinion?
Brilliant Amerikan Medical Doctor ♥️♥️🇷🇺🇷🇺🇷🇺🇷🇺
Tom dayspring on Peter attia’s podcast mentioned that sure niacin improves all those markers but at the end of the day it does not “work” because it actually worsens all cause mortality slightly. So his conclusion is that it must be doing something “bad” that we don’t understand. So it works for the markers but isn’t working….
May have negative effects on pancreas
Will or can Niacin raise your blood sugar? My not so scientific test “seems” like my fasting blood sugar is up slightly on my insulin resistance self when taking Niacin. I “was” pre-diabetic before a low carb diet and losing 30 lbs (20 more lbs to go) and my fasting blood sugar unfortunately still hovers around 95-100 (which I am working on with fasting/intermittent fasting currently) so when my last fasting sugar was solidly past 100 with the “only” known change in diet was Niacin made me ask the question? Any one else experience this? Thanks in advance.
It definitely can. It does raise mine.
Yes. This effect tends to decrease over a few months. For those who take statins, they can as well. But with statins, it’s permanent. Pitavastatin is the exception.
I took 2 g per day for 5+ years and recently stopped due to causing LPB and insulin resistance. I don't know if I resume and stay at lower dosage, there would be any benefits or not. Not much research info since there is NO profitable market for it.
Good video, thanks for sharing.
Thanks!
Hi , ive been taking Niacin for over 10 years 3 grams a day , I'm thinking of including Crestor 2.5 mg 3 times a week , any thoughts on this ?
I also take K2 Mk7 , D3 and a fish oil supplement.
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Many do the same.
How much Induricine please?
What about the E D connection to statins
Thank you. What dose of Niacin please
What is Niacin made of?
My doctor took me off niacin because of the AIm-High report. I would like to go back on niacin ,what should I say to my doctor or should I just take OTC niacin???
Great question.
Hi Doctor .delighted to come across your vid on you tube .I didn’t know there was still this interest in Niacin . Am I ok using Niacinamide instead ? To avoid the flush . Age 74 , overweight .
No. Niacin only in the form of nicotinic acid can lower ldl, triglycerides.
Please do a web search on this paper, "New Perspectives on the Use of Niacin in the Treatment of Lipid Disorders" published in 2014.
In the paper, Figure 1 has the dosing info. Table 2 has the recommendations on how to reduce flushing.
All friends of mine who smocks a lot never had high cholesterol and who never smocked have high cholesterol.Maybe you should think more.
Niacin stops my Leg pain~!
Hmm. That’s interesting. Thanks for sharing that.
The Aim High trial was a bust study. Niaspan (b3)was one of the best products on the market . Post AH trial, many cards and endos walked away from it. What an absolute sad story.
Why?
Hey doc I currently take flush free niacin I am confused should I continue this or go straight to the niacin and start with low levels of niacin and work my way up thank you
Don't use flush free, use (Nicotinic Acid) I use SLO NIACIN. no flush is no good
OH SLO NIACIN is the brand name it makes you flush and thats what you want
OH is not part of the brand name just SLO NIACIN distributed by MainPoint Pharmaceuticals
anniekate1914 thank you for responding should I start out at low levels work my way up I really hate that flush!
anniekate1914 what about for depression and anxiety though? The non flush? Or the normal?
What do you recommend as dosage level for Niacin?
Nancy Ulrich Im actually just wonder this too..🥺.. was thinking of start a niacin course but now I dont know how much I dare to take.. 🥺💚
@@lindaedvardsson4218 Try this book, cheap via Kindle, very detailed: www.amazon.com/Niacin-Story-Wonderful-Healing-Properties/dp/1591202752 Helped me a lot do decide which and how much to take.
@@lindaedvardsson4218 Start VERY low dose and work yourself up to higher doses...VERY slowly. Over weeks and months.
acjitsu Has eaten it before but.. If he had a approx. dosage to take this daily.. for Lyme.. espec. Bartonella.. Do you know?!..🥺💚.. Thank you for answering❣️.. I have to look up all my self due to living in sweden.. I has no doctor that could check me every sec week or so..😣.. 💚❣️
acjitsu which brand do you recommend for mental health? And what dose
I eat a lot of vegetables so I'm not worried about Niacin. And getting one gram out of my half pound bag is not easy.
High dose niacin is hard on the liver. It also robs the body of methyl groups. I won't use amounts that are far out of line with the RDA I have very low Lp(a) without niacin.
LP(a) is primarily genetically driven...
Thanks. I take TMG for the methyl group replenishment.
@@PrevMedHealth how much TMG is required? Also do you have a video explaining the methylation issue when taking niacin?
Would halving my 2 gram niacin morning and night be ok?
Most docs that use niacin think it has to be 2 grams/day. But I have seen improvements with lower doses. The trick is measuring the impact.
Night
Thank you for your video, but I have one question. I take Non-flush Niacin, isn't that just as good as Niacin that causes flush? Thank you for your reply.
Apparently not.
Non flush is pretty much useless
Why is it useless??
@@mik19mazz , the flush is what makes this work to clean arteries. Non flush does not do it.
@@joycemclean9661 thank you
Is niacin hard on the kidneys?
hi Doc, hypothyroid people do not flush when they take immediate release niacin, what's the reason?
Are you sure about that? Have you got any article references?
@@PrevMedHealth I'm hypothyroid....and I flush. That is incorrect information.
avoid grains carbs seed oils then you dont have to worry about statins and cholesterol pr tatins
If I pay for my internet connection why should I have to listen to commercials!
some1forced u at gunpoint to click on this then listen, and then read thru the comments did they,.....dh
I use B3 no flush. Does this work?
Niacinamide work just as good? Or do you need to flush
I don't like to take vitamin supplements so, what foods should I eat that would provide Niacin the best?
Nutritional yeast has all the B vitamins
@@andrewrivera4029 ok cool thanks. Nutritional yeast is found in what food? Bread?
@@hankramos8663 no, there’s stuff called nutritional yeast. Go to the grocery store and ask a clerk.
Does niacin cause diabetes?
But we all know the insulin resistance and high insulin will cause inflammation and subsequently what you just described cholesterol issues
I have just started taking niacin 500mg the flush is severe at the moment but my body will get used to it I intend increasing my dose I am taking it for tiredness and my skin.
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Great video Dr. Brewer
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@@PrevMedHealth Thanks. That's sounds like something I would enjoy.
Took niacin, don't smoke, don't drink, was on a low carb diet, went to the gym fairly regularly. One day, I went to the gym, pushed the sled across the floor about 6 times, had a heart attack. I know that my inflammation is high, but I can't get the doctors to treat that, they just want to push the statins. I had a bad reaction to statins, injuries weren't healing, aches pains, brain fog, depression... Now they have me on ezetimibe, I guess we'll see how this goes. I need to know what the protocol is. Is it a gram twice a day, or once, or can I split a gram between morning and night?
weird, do you take k2 to get the calcium out of your bloodvessels and into your bones?
NMN or NR can be a better alternative to Niacin, though more expensive, they are much more effective
Does niacin raise blood pressure?
Devotional it lowers it for me.
It's side effects is to lower BP
Thank you Dr.
So what is a good dosage for niacin. 500mg? 1 gram per day?
Ditto. How much to take?
The recommend dose is 2 gr./day. Rugby or Enduracin time release, 500mg.
I had a dr. Said 2,000 is good
That’s gm
I'd say it probably depends on whether or not you take a statin and what that dosage is. They both can tax the liver. Just my .02 cents worth.
Hello Doctor, what is the safe dose of niacin for a type 2 diabetic?
❓Maybe LDL is more important than HDL .. .
I get unbearable flush with just 500 mg.
Try sustained release _SloNiacin_ 👌
There is a flush free version of niacin. Is it as effective as regular niacin?
A couple of them : Enduracin and Rugby.