Antibody affinity maturation

This short video describes how the binding strength of antibodies are increased. This process is called affinity maturation of the antibody response and occurs in B cells within the germinal center. This process is regulated by the enzyme activation-induced cytidine deaminase (AID). B cells, which are part of the immune system, play critical roles in the clearance of pathogens from our bodies.
Video by Julian Kirk-Elleker. Brought to you by the Department of Immunology and Biomedical Communications at the University of Toronto.

[@TheChocotiger]

This is amazing, so much respect for the scientists that discovered all this!

[@Tionenji]

So much respect indeed 🙏

[@VedantBhardwaj-n4o]

Honestly God bless you, whoever made this video! I am a medical student at KCL, and this is the best video out there to explain this topic, which I was quite confused with! Thankssssss!!!!

[@johnarnold3757]

This video rules so hard

[@RyanFranzese]

These complex processes cooked up by evolution are wild

[@XENOS1010]

Wow this is supreme

[@Sarah41416]

This is a GREAT WORK

[@mrniceguy4277]

2:18 but this antigen is first processed and presented as peptide on MHC-2 and then the B Cell interacts with the T Cell, right?
T cell receptors recognise peptides bound to MHC, B Cell Receptor (=which essentially is the antibody) recognise the native antigen

[@nadiaporter6758]

Very nice video for a very complicated process!

[@dsavkay]

420 çalışanlar like

[@arielrafie]

Just incredible! Thank you