LNP | PATfix LNP Switcher Feature Demonstration

The PATfix LNP Switcher offers a unique characterization approach to LNP formulations, addressing the limitations of traditional assays that often require multiple time-consuming steps. Utilizing an innovative 2D chromatographic method with two different separation stages, the PATfix Switcher determines crucial LNP quality attributes in a single run without any sample preparation. Unlike other assays, it allows for simultaneous quantification of both encapsulated and naked nucleic acid cargo, including co-encapsulated species, and provides estimates of mRNA fragmentation and LNP